The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Physical frailty predicts future cognitive decline — A four-year prospective study in 2737 cognitively normal older adults
Open accessAbstract
OBJECTIVE: To examine the association between baseline frailty measurements and cognitive function 4 years later. DESIGN: Prospective observational study. SETTING: Community. PARTICIPANTS: Two thousand seven hundred and thirty seven cognitively normal older adults. MEASUREMENT: The appendicular muscle mass (ASM), hand grip strength, timed chair-stand test, walking speed and step length were measured at baseline. The Mini-mental state examination (MMSE) was administered at baseline and 4 years later. RESULTS: In men, all baseline frailty measurements, namely, being underweight, lower ASM, weaker grip strength, slower chair-stand test, shorter step length, slower timed walk were significantly associated with a lower MMSE score 4 years afterwards. After adjustment for age, years of education and baseline MMSE score, ASM and timed walk became insignificant. In women, all frailty measurements except underweight and low ASM were significantly associated with MMSE score 4 years later. Moreover, only weaker grip strength persisted to be significant after adjustment for age, years of education and baseline MMSE score. CONCLUSION: Physical frailty, as represented by being underweight, weaker grip strength, slower chair-stand test, shorter step-length in men and weaker grip strength in women, was associated with cognitive decline over a four year period.
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Frailty in Older Adults: Evidence for a Phenotype
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Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly
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Cited by
Cognitive frailty: Rational and definition from an (I.A.N.A./I.A.G.G.) International Consensus Group
Kelaiditi, E., Cesari, M., Canevelli, M., Abellan van Kan, G., Ousset, P.-J., Gillette-Guyonnet, S., Ritz, P., Duveau, F., Soto, M. E., Provencher, V., et al. (2013) · The Journal of nutrition, health and aging · doi:10.1007/s12603-013-0367-2 · Cited by 1,084
Theou, O., Brothers, T. D., Mitnitski, A., & Rockwood, K. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12420 · Cited by 665
Cognitive frailty, a novel target for the prevention of elderly dependency
Ruan, Q., Yu, Z., Chen, M., Bao, Z., Li, J., & He, W. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2014.12.004 · Cited by 379
Rijk, J. M., Roos, P. R., Deckx, L., van den Akker, M., & Buntinx, F. (2016) · Geriatrics & Gerontology International · doi:10.1111/ggi.12508 · Cited by 376
Transitions in Frailty States Among Community-Living Older Adults and Their Associated Factors
Lee, J. S. W., Auyeung, T.-W., Leung, J., Kwok, T., & Woo, J. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.12.002 · Cited by 324
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Metadata
- Authors
- Auyeung, T. W., Lee, J. S. W., Kwok, T., & Woo, J.
- Venue
- The Journal of nutrition, health and aging
- Publisher
- Elsevier BV
- Published
- 2011-10
- Volume
- 15
- Issue
- 8
- Pages
- 690-694
- ISSN
- 1279-7707 (ISSN-L)
- OpenAlex
- W2024087673
- Cited by
- 248
- References
- 12
- FWCI
- 5.70
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Auyeung, T. W., Lee, J. S. W., Kwok, T., & Woo, J. (2011). Physical frailty predicts future cognitive decline — A four-year prospective study in 2737 cognitively normal older adults. The Journal of nutrition, health and aging. https://doi.org/10.1007/s12603-011-0110-9
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