Role of Nuclear Receptor on Regulation of BDNF and Neuroinflammation in Hippocampus of β-Amyloid Animal Model of Alzheimer’s Disease

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 315,771 · see citing works

A new and rapid colorimetric determination of acetylcholinesterase activity

Ellman, G. L., Courtney, K. D., Andres, V., & Featherstone, R. M. (1961) · Biochemical Pharmacology · doi:10.1016/0006-2952(61)90145-9 · Cited by 27,221 · see citing works

Tissue sulfhydryl groups

Ellman, G. L. (1959) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(59)90090-6 · Cited by 26,383 · see citing works

Methods of Enzymatic Analysis

(1975) · Journal of AOAC INTERNATIONAL · doi:10.1093/jaoac/58.5.1085 · Cited by 20,078 · see citing works

DETERMINATION OF SERUM PROTEINS BY MEANS OF THE BIURET REACTION

Gornall, A. G., Bardawill, C. J., & David, M. M. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)57021-6 · Cited by 16,164 · see citing works

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

Green, L. C., Wagner, D. A., Glogowski, J. A., Skipper, P. L., Wishnok, J. S., & Tannenbaum, S. R. (1982) · Analytical Biochemistry · doi:10.1016/0003-2697(82)90118-x · Cited by 12,089 · see citing works

AN ELECTRON-TRANSPORT SYSTEM ASSOCIATED WITH THE OUTER MEMBRANE OF LIVER MITOCHONDRIA

Sottocasa, G. L., Kuylenstierna, B., Ernster, L., & Bergstrand, A. (1967) · The Journal of Cell Biology · doi:10.1083/jcb.32.2.415 · Cited by 2,316 · see citing works

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

Tanzi, R. E., & Bertram, L. (2005) · Cell · doi:10.1016/j.cell.2005.02.008 · Cited by 1,849 · see citing works

Generation of superoxide radical during autoxidation of hydroxylamine and an assay for superoxide dismutase

Kono, Y. (1978) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(78)90479-4 · Cited by 1,787 · see citing works

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

Laurén, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W., & Strittmatter, S. M. (2009) · Nature · doi:10.1038/nature07761 · Cited by 1,560 · see citing works

Mechanisms of lipid peroxide formation in animal tissues

Wills, E. D. (1966) · Biochemical Journal · doi:10.1042/bj0990667 · Cited by 1,348 · see citing works

Methods of Enzymatic Analysis

Matthews, R. (1987) · Journal of Clinical Pathology · doi:10.1136/jcp.40.8.934-a · Cited by 1,187 · see citing works

Mechanism of Cellular 3‐(4,5‐Dimethylthiazol‐2‐yl)‐2,5‐Diphenyltetrazolium Bromide (MTT) Reduction

Liu, Y., Peterson, D. A., Kimura, H., & Schubert, D. A. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69020581.x · Cited by 1,037 · see citing works

Emerging roles of PPARS in inflammation and immunity

Daynes, R. A., & Jones, D. C. (2002) · Nature reviews. Immunology · doi:10.1038/nri912 · Cited by 922 · see citing works

Brain-derived neurotrophic factor is reduced in Alzheimer's disease

Connor, B., Young, D., Yan, Q., Faull, R. L. M., Synek, B., & Dragunow, M. (1997) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00125-3 · Cited by 581 · see citing works

Acute treatment with the PPARγ agonist pioglitazone and ibuprofen reduces glial inflammation and Aβ1–42 levels in APPV717I transgenic mice

Heneka, M. T., Sastre, M., Dumitrescu-Ozimek, L., Hanke, A., Dewachter, I., Kuiperi, C., O'Banion, K., Klockgether, T., Van Leuven, F., & Landreth, G. E. (2005) · Brain · doi:10.1093/brain/awh452 · Cited by 565 · see citing works

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

Mark, R. J., Hensley, K., Butterfield, D. A., & Mattson, M. P. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-09-06239.1995 · Cited by 553 · see citing works

[58] Preparation of succinate dehydrogenase and reconstitution of succinate oxidase

King, T. E. (1967) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(67)10061-x · Cited by 533 · see citing works

Amnesia induced in mice by centrally administered β-amyloid peptides involves cholinergic dysfunction

Maurice, T., Lockhart, B. P., & Privat, A. (1996) · Brain Research · doi:10.1016/0006-8993(95)01032-7 · Cited by 524 · see citing works

Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation of β-Secretase

Sastre, M., Dewachter, I., Landreth, G. E., Willson, T. M., Klockgether, T., LEUVEN, F. V., & Heneka, M. T. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-30-09796.2003 · Cited by 359 · see citing works

Mitochondria, calcium and cell death: A deadly triad in neurodegeneration

Celsi, F., Pizzo, P., Brini, M., Leo, S., Fotino, C., Pinton, P., & Rizzuto, R. (2009) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2009.02.021 · Cited by 321 · see citing works

[52] Preparations and properties of soluble NADH dehydrogenases from cardiac muscle

King, T. E., & Howard, R. L. (1967) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(67)10055-4 · Cited by 292 · see citing works

PPARγ Agonists as Therapeutics for the Treatment of Alzheimer's Disease

Landreth, G. E., Jiang, Q., Mandrekar, S., & Heneka, M. T. (2008) · Neurotherapeutics · doi:10.1016/j.nurt.2008.05.003 · Cited by 277 · see citing works

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo

Umeda, T., Tomiyama, T., Sakama, N., Tanaka, S., Lambert, M. P., Klein, W. L., & Mori, H. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22640 · Cited by 264 · see citing works

Stress increases brain-derived neurotropic factor messenger ribonucleic acid in the hypothalamus and pituitary

Smith, M. A., Makino, S., Kim, S. Y., & Květňanský, R. (1995) · Endocrinology · doi:10.1210/endo.136.9.7649080 · Cited by 226 · see citing works

Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by d-galactose in mice

Kumar, A., Prakash, A. K., & Dogra, S. (2009) · Food and Chemical Toxicology · doi:10.1016/j.fct.2009.11.043 · Cited by 192 · see citing works

Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: Implications for multiple sclerosis

Storer, P. D., Xu, J., Chavis, J. A., & Drew, P. D. (2005) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.12.015 · Cited by 183 · see citing works

Mild cognitive impairment in prediagnosed Huntington disease

Duff, K., Paulsen, J. S., Mills, J. A., Beglinger, L. J., Moser, D. J., Smith, M. M., Langbehn, D. R., Stout, J. C., Queller, S., & Harrington, D. L. (2010) · Neurology · doi:10.1212/wnl.0b013e3181eccfa2 · Cited by 179 · see citing works

Peroxisome Proliferator-Activated Receptor γ Induces a Clearance Mechanism for the Amyloid-β Peptide

Espuny-Camacho, I., Serneels, L., Spittaels, K., Merchiers, P., Dominguez, D. I., & Strooper, B. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3987-04.2004 · Cited by 169 · see citing works

Cognition and beta-amyloid in preclinical Alzheimer's disease: data from the AIBL study.

Pike, K., Ellis, K., Villemagne, V., Good, N. M., Chételat, G., Ames, D., Szoeke, C., Laws, S., Verdile, G., Martins, R., et al. (2011) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2011.04.012 · Cited by 167 · see citing works

Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat

Ferrer, I., Krupinski, J., Goutan, E., Martí, E., Ambrosio, S., & Arenas, E. (2001) · Acta Neuropathologica · doi:10.1007/s004010000268 · Cited by 153 · see citing works

Alzheimer's disease: Effects of β-amyloid on mitochondria

Tillement, L., Lecanu, L., & Papadopoulos, V. (2010) · Mitochondrion · doi:10.1016/j.mito.2010.08.009 · Cited by 145 · see citing works

Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF

Diógenes, M., Costenla, A. R., Lopes, L. V., Jerónimo-Santos, A., Sousa, V., Fontinha, B., Ribeiro, J., & Sebastião, A. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.64 · Cited by 144 · see citing works

PPARγ stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss

Miglio, G., Rosa, A. C., Rattazzi, L., Collino, M., Lombardi, G., & Fantozzi, R. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.05.001 · Cited by 131 · see citing works

Impact and Therapeutic Potential of PPARs in Alzheimers Disease

Heneka, M. T., Reyes-Irisarri, E., Hull, M. J., & Kummer, M. P. (2011) · Current Neuropharmacology · doi:10.2174/157015911798376325 · Cited by 124 · see citing works

Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation

Bishop‐Bailey, D., & Byström, J. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.06.011 · Cited by 120 · see citing works

New Insights in the Amyloid-Beta Interaction with Mitochondria

Spuch, C., Ortolano, S., & Fernández-Balbuena, C. N. (2012) · Journal of Aging Research · doi:10.1155/2012/324968 · Cited by 117 · see citing works

Role of PPAR-γ Ligands In Neuroprotection against Glutamate-Induced Cytotoxicity in Retinal Ganglion Cells

Aoun, P., Simpkins, J. W., & Agarwal, N. A. (2003) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.02-1060 · Cited by 115 · see citing works

PPARγ as a therapeutic target in central nervous system diseases

Sundararajan, S. S., Jiang, Q., Heneka, M. T., & Landreth, G. E. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.03.020 · Cited by 107 · see citing works

Role of aggregation conditions in structure, stability, and toxicity of intermediates in the Aβ fibril formation pathway

Lee, S., Fernández, E., & Good, T. A. (2007) · Protein Science · doi:10.1110/ps.062514807 · Cited by 104 · see citing works

Environmental Enrichment Influences BDNF and NR1 Levels in the Hippocampus and Restores Cognitive Impairment in Chronic Cerebral Hypoperfused Rats

Sun, H., Zhang, J., Zhang, L., Liu, H., Zhu, H., & Yang, Y. (2010) · Current Neurovascular Research · doi:10.2174/156720210793180819 · Cited by 83 · see citing works

Role of peroxisome proliferator-activated receptor γ in amyloid precursor protein processing and amyloid β-mediated cell death

d’Abramo, C., Massone, S., Zingg, J.-M., Pizzuti, A., Marambaud, P., Piccola, B. D., Azzi, A., Marinari, U. M., Pronzato, M. A., & Ricciarelli, R. (2005) · Biochemical Journal · doi:10.1042/bj20050560 · Cited by 81 · see citing works

Puerarin protects PC12 cells against β‐amyloid‐induced cell injury

Zhang, H., Liu, Y., Wang, H., Xu, J., & Hu, H. (2008) · Cell Biology International · doi:10.1016/j.cellbi.2008.07.006 · Cited by 81 · see citing works

Effect of N‐Acetyl Cysteine against Aluminium‐induced Cognitive Dysfunction and Oxidative Damage in Rats

Prakash, A. K., & Kumar, A. (2009) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2009.00404.x · Cited by 80 · see citing works

Appearance of amyloid β-like substances and delayed-type apoptosis in rat hippocampus CA1 region through aging and oxidative stress

Fukui, K., Takatsu, H., Shinkai, T., et al. (2005) · Journal of Alzheimer s Disease · doi:10.3233/jad-2005-8309 · Cited by 79 · see citing works

Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models

Reddy, P. H., & McWeeney, S. K. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.04.014 · Cited by 73 · see citing works

ICV STZ induced impairment in memory and neuronal mitochondrial function: A protective role of nicotinic receptor

Saxena, G., Patro, I. K., & Nath, C. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.04.039 · Cited by 73 · see citing works

Amyloid and Alzheimer's Disease: Inside and Out

Tam, J. H. K., & Pasternak, S. (2012) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/s0317167100013408 · Cited by 64 · see citing works

The nuclear receptor PPARγ as a therapeutic target for cerebrovascular and brain dysfunction in Alzheimer's disease

Nicolakakis, N. (2010) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2010.00021 · Cited by 60 · see citing works

A case for a non‐transgenic animal model of Alzheimer's disease

Stéphan, A., & Phillips, A. G. (2005) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2004.00113.x · Cited by 58 · see citing works

Suppression of nitric oxide synthesis by L-NAME reverses the beneficial effects of pioglitazone on scopolamine-induced memory impairment in mice

Allami, N., Paydar, M. J., Rayatnia, F., Sehhat, K., Rahimian, R., Norouzi, A., & Dehpour, A. R. (2010) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.10.007 · Cited by 56 · see citing works

Pioglitazone alleviates the mitochondrial apoptotic pathway and mito‐oxidative damage in the d ‐galactose‐induced mouse model

Prakash, A. K., & Kumar, A. (2013) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/1440-1681.12144 · Cited by 42 · see citing works

Exploring mechanism of pioglitazone‐induced memory restorative effect in experimental dementia

Kaur, B., Singh, N., & Jaggi, A. S. (2009) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2009.00708.x · Cited by 39 · see citing works

Why Alzheimer's Disease Starts with a Memory Impairment: Neurophysiological Insight

Arshavsky, Y. I. (2010) · Journal of Alzheimer s Disease · doi:10.3233/jad-2010-1339 · Cited by 29 · see citing works

Overexpression of cellular prion protein (PrPC) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ1–40) administration in mice

Rial, D., Piermartiri, T., Duarte, F. S., Tasca, C. I., Walz, R., & Prediger, R. D. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.04.034 · Cited by 25 · see citing works

Effects of trans-2,4-dimethoxystibene against the neurotoxicity induced by Aβ25–35 both in vitro and in vivo

Ruan, C., Zhang, L., Chen, D., et al. (2010) · Neuroscience Research · doi:10.1016/j.neures.2010.03.009 · Cited by 19 · see citing works

Neuroinflammation and Common Mechanism in Alzheimer’s Disease and Prion Amyloidosis: Amyloid-Associated Proteins, Neuroinflammation and Neurofibrillary Degeneration

Rozemüller, A. J. M., Jansen, C., Carrano, A., et al. (2012) · Neurodegenerative Diseases · doi:10.1159/000335380 · Cited by 18 · see citing works

Designing clinical trials for early (pre-dementia) Alzheimer's disease: Determining the appropriate population for treatment

Siemers, E. (2011) · The journal of nutrition health & aging · doi:10.1007/s12603-011-0008-6 · Cited by 12 · see citing works

Brain-Derived Neurotrophic Factor in Brain Disorders: Focus on Neuroinflammation

Lima Giacobbo, B., Doorduin, J., Klein, H. C., Dierckx, R. A. J. O., Bromberg, E., & de Vries, E. F. J. (2019) · Molecular Neurobiology · doi:10.1007/s12035-018-1283-6 · Cited by 750 · see citing works

The neuroprotective effects of glucagon-like peptide 1 in Alzheimer’s and Parkinson’s disease: An in-depth review

Reich, N., & Hölscher, C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.970925 · Cited by 248 · see citing works

Molecular mechanisms of brain-derived neurotrophic factor in neuro-protection: Recent developments

Zhao, H., Alam, A., San, C.-Y., Eguchi, S., Chen, Q., Lian, Q., & Ma, D. (2017) · Brain Research · doi:10.1016/j.brainres.2017.03.029 · Cited by 122 · see citing works

Monitoring 5HT Metabolism in the Brain of the Freely Moving Rat

Hutson, P. H., Sarna, G. S., Sahakian, B. J., Dourish, C. T., & Curzon, G. (1986) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1986.tb23626.x · Cited by 15 · see citing works

Nerve growth factor‐induced changes in neural cell adhesion molecule (N‐CAM) in PC12 cells.

Prentice, H. M., Moore, S. E. H., Dickson, J. G., et al. (1987) · The EMBO Journal · doi:10.1002/j.1460-2075.1987.tb02444.x · Cited by 88 · see citing works

Sections on Neurochemistry and Child Neurology

(1968) · Neurology · doi:10.1212/wnl.18.3.297 · Cited by 1 · see citing works

An association between migraine and cutaneous allodynia

Burstein, R., Yarnitsky, D., Goor‐Aryeh, I., Ransil, B. J., & Bajwa, Z. H. (2000) · Annals of Neurology · doi:10.1002/1531-8249(200005)47:5 · Cited by 1,013 · see citing works

STUDIES ON THE METABOLIC EFFECTS OF A SUBSTANCE FOUND IN PERIPHERAL NERVE

Heller, I. H., Wolfe, L. S., & Hesse, S. (1962) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1962.tb09472.x · Cited by 5 · see citing works