The DOI matches its Crossref record; 179 of the 179 references it cites were found in a registry or an index.
Mapping the epigenetic modifications of DNA and RNA
Open accessAbstract
Over 17 and 160 types of chemical modifications have been identified in DNA and RNA, respectively. The interest in understanding the various biological functions of DNA and RNA modifications has lead to the cutting-edged fields of epigenomics and epitranscriptomics. Developing chemical and biological tools to detect specific modifications in the genome or transcriptome has greatly facilitated their study. Here, we review the recent technological advances in this rapidly evolving field. We focus on high-throughput detection methods and biological findings for these modifications, and discuss questions to be addressed as well. We also summarize third-generation sequencing methods, which enable long-read and single-molecule sequencing of DNA and RNA modification.
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Cites
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Self-citationALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
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Cited by
Exploring Epigenomic Datasets by ChIPseeker
Wang, Q., Li, M., Wu, T., Zhan, L., Li, L., Chen, M., Xie, W., Xie, Z., Hu, E., Xu, S., et al. (2022) · Current Protocols · doi:10.1002/cpz1.585 · Cited by 415
The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
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Mapping epigenetic modifications by sequencing technologies
Chen, X., Xu, H., Shu, X., & Song, C.-X. (2025) · Cell Death & Differentiation · doi:10.1038/s41418-023-01213-1 · Cited by 105
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Metadata
- Authors
- Zhao, L.-Y., Song, J., Liu, Y., Song, C.-X., & Yi, C.
- Venue
- Protein & Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 2020-05-22
- Volume
- 11
- Issue
- 11
- Pages
- 792-808
- ISSN
- 1674-800X (ISSN-L)
- 1674-8018
- OpenAlex
- W3027531807
- Cited by
- 361
- References
- 179
- FWCI
- 11.96
- Type
- journal article
- Language
- en
- Open access
- gold
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