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The Clinical Trials Gap for Adolescents and Young Adults with Cancer: Recent Progress and Conceptual Framework for Continued Research

Freyer, David R., Seibel, Nita L.·2015·Current Pediatrics Reports
DOI 10.1007/s40124-015-0075-yPMC PMC6319956
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Research works printed but not linked: 40

  1. Centers for Disease Control and Prevention. Cancer survivors—United States, 2007. MMWE Morb Mortal Wkly Rep. 2011;60(9):269–72.
  2. Bleyer WA, Tejeda H, Murphy SB, et al. National cancer clinical trials: children have equal access; adolescents do not. J Adol Health. 1997;21(6):366–73. · DOI
  3. Albritton K, Bleyer WA. The management of cancer in the older adolescent. Eur J Cancer. 2003;39(18):2584–99. · DOI
  4. Bleyer A, Montello M, Budd T, Saxman S. National survival trends of young adults with sarcoma: lack of progress is associated with lack of clinical trial participation. Cancer. 2005;103(9):1891–7. · DOI
  5. Adolescent and Young Adult Progress Review Group: National Cancer Institute and LiveStrong Young Adult Alliance. Closing the gap: research and care imperatives for adolescents and young adults with cancer. Bethesda: National Institutes of Health; 2006. NIH Publication 06-6067.
  6. Bleyer A. Young adult oncology: the patients and their survival challenges. CA Cancer J Clin. 2007;57(4):242–55. · DOI
  7. Tricoli JV, Seibel NL, Blair DG, et al. Unique characteristics of adolescent and young adult acute lymphoblastic leukemia, breast cancer, and colon cancer. J Natl Cancer Inst. 2011;103(8):628–35. · DOI
  8. Perez-Andreu V, Roberts KG, Xu H, et al. A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults. Blood. 2014;. doi: 10.1182/blood-2014-09-595744 . · DOI
  9. • Canner J, Alonzo TA, Franklin J et al. Differences in outcomes of newly diagnosed acute myeloid leukemia for adolescent/young adult and younger patients: a report from the Children’s Oncology Group. Cancer. 2013;119(23):4162–9. This paper reports significantly greater treatment-related mortality for older adolescents treated for acute myeloid leukemia. · DOI
  10. Veal GJ, Hartford CM, Stewart CF. Clinical pharmacology in the adolescent oncology patient. J Clin Oncol. 2010;28(32):4790–9. · DOI
  11. • Bhatia S, Landier W, Shanqquan M et al. Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the Children’s Oncology Group. J Clin Oncol. 2012;30(17):2094–101. This study determined that adolescents undergoing treatment for ALL were significantly less likely to be adherent taking oral chemotherapy and more likely to experience leukemic relapse compared with younger children. · DOI
  12. Martin S, Ulrich C, Munsell M, et al. Delays in cancer diagnosis in underinsured young adults and older adolescents. Oncologist. 2007;12(7):816–24. · DOI
  13. Pollock BH, Krischer JP, Vietti TJ. Interval between symptom onset and diagnosis of pediatric solid tumors. J Pediatr. 1991;119(5):725–32. · DOI
  14. Parsons HM, Schmidt S, Harlan LC, et al. Young and uninsured: insurance patterns of recently diagnosed adolescent and young adult cancer survivors in the AYA HOPE study. Cancer. 2014;120(15):2352–60. · DOI
  15. Krailo M, Bernstein L, Sullivan-Halley J, Hammond GD. Patterns of enrollment on cooperative group studies: an analysis of trends from the Los Angeles County Cancer Surveillance Program. Cancer. 1993;71(10 Suppl):3325–30. · DOI
  16. Liu L, Krailo M, Reaman GH, et al. Childhood cancer patients’ access to cooperative group cancer programs: a population-based study. Cancer. 2003;97(5):1339–45. · DOI
  17. Fern LA, Whelan J. Recruitment of adolescents and young adults to cancer clinical trials—international comparisons, barriers, and implications. Semin Oncol. 2010;37(2):e1–8. · DOI
  18. Shaw PH, Ritchey AK. Different rates of clinical trial enrollment between adolescents and young adults aged 15-22 years old and children under 15 years old with cancer at a children’s hospital. J Pediatr Hematol Oncol. 2007;29(12):811–4. · DOI
  19. Downs-Canner S, Shaw PH. A comparison of clinical trial enrollment between adolescent and young adult (AYA) oncology patients treated at affiliated adult and pediatric oncology centers. J Pediatr Hematol Oncol. 2009;31(12):927–9. · DOI
  20. Parsons HM, Harlan LC, Seibel NL, et al. Clinical trial participation and time to treatment among adolescents and young adults with cancer: does age at diagnosis make a difference? J Clin Oncol. 2011;29(30):4045–53. · DOI
  21. Collins C, Freyer DR. Deficits in clinical trial enrollment among adolescents and young adults with cancer treated at an academic medical center. Pediatr Blood Cancer. 2014;61(S2):S344.
  22. Bleyer A, Ulrich C, Martin S. Young adults, cancer, health insurance, socioeconomic status, and the patient protection and affordable care act. Cancer. 2012;118(24):6018–21. · DOI
  23. Ferrari A, Montello M, Budd T, Bleyer A. The challenges of clinical trials for adolescents and young adults with cancer. Pediatr Blood Cancer. 2008;50(5 Suppl):1101–4. · DOI
  24. Albritton KH, Wiggins CH, Nelson HE, Weeks JC. Site of oncologic specialty care for older adolescents in Utah. J Clin Oncol. 2007;25(29):4616–21. · DOI
  25. Yeager ND, Hoshaw-Woodard S, Ruymann FB, Termuhlen A. Patterns of care among adolescents with malignancy in Ohio. J Pediatr Hematol Oncol. 2006;28(1):17–22.
  26. • Wolfson J, Sun CL, Tongiun K et al. Impact of treatment site in adolescents and young adult with central nervous system tumors. J Natl Cancer Inst. 2014;106(8). doi: 10.1093/jnci/dju166 . This study found that AYAs with CNS tumors fare better when treated at NCI-designated Comprehensive Cancer Centers but are less likely to receive care at those sites due to identified referral barriers. · DOI
  27. • Buchanan ND, Block R, Smith AW, Tai E. Psychosocial barriers and facilitators to clinical trial enrollment and adherence for adolescents with cancer. Pediatr. 2014;133(S3):S123–30. This is a lucid, comprehensive review of current research about psychosocial factors influencing cancer clinical trial participation by older adolescents. · DOI
  28. •• Fern LA, Lewandowski JA, Coxon KM, Whelan J. Available, accessible, aware, appropriate, and acceptable: a strategy to improve participation of teenagers and young adults in cancer trials. Lancet Oncol. 2014;15(8):e341–50. This paper provides data indicating positive impact of a national-level strategy to overcome age as a barrier in clinical trial development and recruitment in the UK. · DOI
  29. Institute of Medicine. Implementing a national cancer clinical trials system for the 21st century: workshop summary. Washington: The National Academies Press; 2011.
  30. National Cancer Institute. NCI Central Institutional Review Board Initiative. Available at: https://ncicirb.org (accessed January 17, 2015).
  31. Gupta AA, Indelicato DJ. Increasing the number of clinical trials available to adolescents diagnosed with cancer. Pediatr. 2014;133(S3):S114–8. · DOI
  32. Seibel NL, Hunsberger S, O’Mara AM et al. Adolescent and young adult oncology patient enrollments onto National Cancer Institute-supported trials from 2000–2010. J Clin Oncol. 2014;32(5S):Suppl (Abstract 10058). · DOI
  33. Albritton KH, Coccia P. Influencing referral of adolescents and young adults with cancer to sites with higher rates of trial enrollment. Pediatrics. 2014;133(S3):S104–8. · DOI
  34. Felgenhauer J, Hooke MC. Regulatory barriers to clinical trial enrollment of adolescent and young adult oncology patients. Pediatrics. 2014;133(S3):S119–22. · DOI
  35. Kaplan CP, Nápoles AM, Dohan D, et al. Clinical trial discussion, referral, and recruitment: physician, patient, and system factors. Cancer Causes Control. 2013;24(5):979–88. · DOI
  36. Siminoff LA, Zhang A, Colabianchi N, et al. Factors that predict the referral of breast cancer patients onto clinical trials by their surgeons and medical oncologists. J Clin Oncol. 2000;18(6):1203–11. · DOI
  37. •• Shaw PH, Boyiadzis M, Tawbi H et al. Improved clinical trial enrollment in adolescent and young adult (AYA) oncology patients after the establishment of an AYA oncology program uniting pediatric and medical oncology divisions. Cancer. 2012;118(14):3614–7. This study reports data demonstrating how establishing an AYA program may be an effective means for improving clinical trial enrollment of young adults in an academic medical center. · DOI
  38. Shaw PH, Hayes-Lattin B, Johnson R, Bleyer A. Improving enrollment in clinical trials for adolescents with cancer. Pediatrics. 2014;133(S3):S109–13. · DOI · Paper page
  39. Read K, Fernandez CV, Gao J, et al. Decision-making by adolescents and parents of children with cancer regarding health research participation. Pediatrics. 2009;124(3):959–65. · DOI
  40. Freyer DR, Felgenhauer J, Perentesis J. Children’s Oncology Group’s 2013 blueprint for research: adolescent and young adult oncology. Pediatr Blood Cancer. 2013;60(6):1055–8. · DOI

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Metadata

Authors
Freyer, D. R., & Seibel, N. L.
Venue
Current Pediatrics Reports
Publisher
Springer Science and Business Media LLC
Published
2015-02-18
Volume
3
Issue
2
Pages
137-145
ISSN
2167-4841
DOI
10.1007/s40124-015-0075-y
PMC
PMC6319956
Cited by
65
References
2
Language
en
Licence
www.springer.com/tdm (tdm)

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