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Cited by 126Cardiovascular Syncope and Autonomic DisordersCardiac electrophysiology and arrhythmiasVestibular and auditory disorders

Diagnostic and prognostic implicatioins of recurrences in patients with syncope

Kapoor, Wishwa N., Peterson, Jacqueline, Wieand, Harry S., Karpf, Michael·1987·The American Journal of Medicine
DOI 10.1016/0002-9343(87)90901-6
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Abstract

The incidence and the diagnostic and prognostic implications of recurrences in 433 patients enrolled in a prospective syncope study are reported. Over a mean follow-up of 30 months, 146 patients had recurrent syncope. Patients with an initial diagnosis of a cardiovascular cause of syncope had a recurrence rate of 31 percent, patients with a noncardiovascular cause had a recurrence rate of 36 percent, and patients with syncope of unknown origin had a recurrence rate of 43 percent at three years (these differences were not significant; the minimum for any two-way comparison was p greater than or equal to 0.11). In eight of the 191 patients in whom a cause of syncope could not be found on initial evaluation, a diagnosis was assigned in follow-up after recurrent syncope. Recurrences led to major morbidity in eight of 146 patients (5 percent) and minor trauma in 10 patients (7 percent). Using recurrence as a time-dependent variable in the Cox models, it was found that this variable was not a significant predictor of overall mortality or sudden death. It is concluded that recurrences are common in patients with syncope, but new diagnosis are rarely established on the basis of evaluation of recurrences. Recurrences are not predictors of mortality or sudden death.

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Crossref · 10.1016/0002-9343(87)90901-6

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  • Clinical decision rules can predict poor outcomes, but most syncope deaths and many poor outcomes are associated with underlying illness rather than syncope per se, particularly in the long term.

    “Clinical decision rules can predict poor outcomes, but most syncope deaths and many poor outcomes are associated with underlying illness rather than syncope per se , 58 particularly in the long term. 56”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [58]

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Authors
Kapoor, W. N., Peterson, J., Wieand, H. S., & Karpf, M.
Affiliations
University of Pittsburgh (US)
Corresponding author
Kapoor, Wishwa N.
Venue
The American Journal of Medicine
Publisher
Elsevier BV
Published
1987-10
Volume
83
Issue
4
Pages
700-708
ISSN
0002-9343 (ISSN-L)
DOI
10.1016/0002-9343(87)90901-6
OpenAlex
W1964652496
Cited by
126
References
60
Citations by year
2024: 1 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 1 · 2019: 2 · 2018: 3 · 2017: 4 · 2016: 1 · 2015: 1 · 2014: 3 · 2013: 6 · 2012: 5
FWCI
4.09
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • The American Journal of Medicine (publishedVersion)
  • PubMed (publishedVersion)
Funders
U.S. Public Health Service (1K04L 01899-01A1)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
Keywords
syncope, recurrent syncope, cardiovascular syncope, syncope of unknown origin, syncope diagnosis, mortality, sudden death, morbidity
MeSH terms
Cardiovascular Diseases, Death, Sudden, Female, Follow-Up Studies, Humans, Male, Middle Aged, Models, Theoretical, Prognosis, Prospective Studies, Recurrence, Risk Factors, Syncope, Time Factors

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