The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Tumor necrosis factor provokes superoxide anion generation from neutrophils
Open accessAbstract
We report that tumor necrosis factor (TNF) provokes superoxide anion generation from human neutrophils. Superoxide anion generation was provoked at TNF concentration of 1 X 10(-11) M and maximal generation was attained at TNF concentration of 1 X 10(-9) M. We also show that movements of intracellular calcium may mediate the TNF-stimulated superoxide anion generation because 8-(diethylamino) octyl 3,4,5-trimethoxybenzoate hydrochloride--but not extracellular EGTA--inhibited the generation of superoxide anion. These results suggest that TNF may mediate some mechanisms of host defense by provoking superoxide anion generation from neutrophils.
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Cites
Isolation of mononuclear cells and granulocytes from human blood.
Bøyum, A. (1968) · Scandinavian Journal of Clinical and Laboratory Investigation · Cited by 9,585
Bertolini, D. R., Nedwin, G. E., Bringman, T. S., Smith, D. D., & Mundy, G. R. (1986) · Nature · doi:10.1038/319516a0 · Cited by 1,434
Dayer, J. M., Beutler, B., & Cerami, A. (1985) · The Journal of experimental medicine · doi:10.1084/jem.162.6.2163 · Cited by 1,216
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
Beutler, B., Greenwald, D., Hulmes, J. D., Chang, M., Pan, Y.-C. E., Mathison, J., Ulevitch, R., & Cerami, A. (1985) · Nature · doi:10.1038/316552a0 · Cited by 1,131
Shalaby, M. R., Aggarwal, B. B., Rinderknecht, E., Svedersky, L. P., Finkle, B. S., & Palladino, M. A. (1985) · The Journal of Immunology · doi:10.4049/jimmunol.135.3.2069 · Cited by 913
Oxidants from phagocytes: agents of defense and destruction
Babior, B. (1984) · Blood · doi:10.1182/blood.v64.5.959.959 · Cited by 807
Pober, J. S., Bevilacqua, M. P., Mendrick, D. L., Lapierre, L. A., Fiers, W., & Gimbrone, M. A. (1986) · The Journal of Immunology · doi:10.4049/jimmunol.136.5.1680 · Cited by 736
Wacker, W. E. C., Ulmer, D. D., & Vallee, B. L. (1956) · New England Journal of Medicine · doi:10.1056/nejm195609062551001 · Cited by 655
Vilcek, J., Palombella, V. J., Henriksen-DeStefano, D., Swenson, C., Feinman, R., Hirai, M., & Tsujimoto, M. (1986) · The Journal of experimental medicine · doi:10.1084/jem.163.3.632 · Cited by 640
Self-citationA Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
Torti, F. M., Dieckmann, B., Beutler, B., Cerami, A., & Ringold, G. M. (1985) · Science · doi:10.1126/science.3839597 · Cited by 518
Cited by
Secretory products of macrophages.
Nathan, C. F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112815 · Cited by 2,615
Induction of manganous superoxide dismutase by tumor necrosis factor: possible protective mechanism
Wong, G. H. W., & Goeddel, D. V. (1988) · Science · doi:10.1126/science.3263703 · Cited by 914
Bozkurt, B., Kribbs, S. B., Clubb, F. J., Michael, L. H., Didenko, V. V., Hornsby, P. J., Seta, Y., Oral, H., Spinale, F. G., & Mann, D. L. (1998) · Circulation · doi:10.1161/01.cir.97.14.1382 · Cited by 821
Cell Death Mechanisms and the Immune System
Golstein, P., Ojcius, D. M., & Young, J. D. (1991) · Immunological Reviews · doi:10.1111/j.1600-065x.1991.tb00822.x · Cited by 447
Kapadia, S., Lee, J., Torre-Amione, G., Birdsall, H. H., Ma, T. S., & Mann, D. L. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118090 · Cited by 437
Metadata
- Authors
- Tsujimoto, M., Yokota, S., Vilček, J., & Weissmann, G.
- Venue
- Biochemical and Biophysical Research Communications
- Publisher
- Elsevier BV
- Published
- 1986-06
- Volume
- 137
- Issue
- 3
- Pages
- 1094-1100
- ISSN
- 0006-291X (ISSN-L)
- OpenAlex
- W2025098696
- Cited by
- 301
- References
- 17
- FWCI
- 9.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Tsujimoto, M., Yokota, S., Vilček, J., & Weissmann, G. (1986). Tumor necrosis factor provokes superoxide anion generation from neutrophils. Biochemical and Biophysical Research Communications. https://doi.org/10.1016/0006-291x(86)90337-2
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
