The DOI matches its Crossref record; 30 of the 31 references it cites were found in a registry or an index.
The dopaminergic innervation of the supraoptic and paraventricular nucleus. A light and electron microscopical study
Open accessAbstract
An antiserum that has been raised against glutaraldehyde-conjugated dopamine was used to demonstrate specifically dopamine in the rat hypothalamus. This dopamine antiserum permitted an optimal fixation with glutaraldehyde and therefore enabled the simultaneous light and electron microscopic immunocytochemical localization of dopamine. It was demonstrated that the paraventricular and supraoptic nuclei of the hypothalamus were innervated by thin dopaminergic fibers, in contrast to the suprachiasmatic nucleus, which hardly received any dopaminergic input. Ultrastructural observations revealed that the dopamine fibers terminated synaptically on the magnocellular neurons and their processes. It is concluded that the present results may explain the effect of centrally injected dopamine on vasopressin and oxytocin release. In the dopamine-containing terminals the reaction product was frequently observed in 90 nm dense core vesicles and around clear vesicles.
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“Additionally, the PVN and the SON express DA receptors and receive dopaminergic innervations, possibly from the VTA (Buijs et al., 1984; Decavel et al., 1987; He et al., 2021; Rivkees and Lachowicz, 1997).”
From Convergence of oxytocin and dopamine signalling in neuronal circuits: Insights into the neurobiology of social interactions across species (2024) · cites this paper as Buijs et al., 1984
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“In addition, the VTA, NAc, and AMY express both OXTR and DA receptors (Baskerville et al., 2009; Buijs et al., 1984; Roeling et al., 1993).”
From Convergence of oxytocin and dopamine signalling in neuronal circuits: Insights into the neurobiology of social interactions across species (2024) · cites this paper as Buijs et al., 1984
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Frontiers in Neuroendocrinology, 1969.
(1970) · Annals of Internal Medicine · doi:10.7326/0003-4819-72-1-153_3 · Cited by 1,119
Sawchenko, P. E., & Swanson, L. W. (1981) · Science · doi:10.1126/science.7292008 · Cited by 588
Björklund, A., Moore, R. Y., Nobin, A., & Stenevi, U. (1973) · Brain Research · doi:10.1016/0006-8993(73)90371-5 · Cited by 514
Vandesande, F., & Dierickx, K. (1975) · Cell and Tissue Research · doi:10.1007/bf00218970 · Cited by 496
Norepinephrine and dopamine content of hypothalamic nuclei of the rat
Palkovits, M., Brownstein, M., Saavedra, J. M., & Axelrod, J. (1974) · Brain Research · doi:10.1016/0006-8993(74)90810-5 · Cited by 457
Swanson, L. W., Sawchenko, P. E., Bérod, A., Hartman, B. K., Helle, K. B., & VanOrden, D. E. (1981) · The Journal of Comparative Neurology · doi:10.1002/cne.901960207 · Cited by 376
The descending afferent connections of the paraventricular nucleus of the hypothalamus (PVN)
Silverman, A., Hoffman, D. L., & Zimmerman, E. A. (1981) · Brain Research Bulletin · doi:10.1016/s0361-9230(81)80068-8 · Cited by 326
Immunofluorescence of vasopressin and oxytocin in the rat hypothalamo-neurohypophyseal system
Swaab, D. F., Pool, C. W., & Nijveldt, F. (1975) · Journal of Neural Transmission · doi:10.1007/bf01253126 · Cited by 323
Self-citationFirst demonstration of highly specific and sensitive antibodies against dopamine
Geffard, M., Buijs, R. M., Séguéla, P., Pool, C. W., & Moal, M. L. (1984) · Brain Research · doi:10.1016/0006-8993(84)91323-4 · Cited by 250
Self-citationTribollet, E., & Dreifuss, J. J. (1981) · Neuroscience · doi:10.1016/0306-4522(81)90190-1 · Cited by 203
Cited by
Sorted by citations
Items 201–226 of 226
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Tasker, J. G., Boudaba, C., Poulain, D. A., & Theodosis, D. T. (2002) · Elsevier eBooks · doi:10.1016/b978-012532104-4/50061-5 · Cited by 2
Neuronal-Glial and Synaptic Plasticity in the Adult Oxytocinergic System
Theodosis, D. T., Poulain, D. A., Montagnese, C. M., & Vincent, J. D. (1988) · Springer eBooks · doi:10.1007/978-1-4684-5502-1_18 · Cited by 2
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Budniok, S., Callaerts‐Vegh, Z., Bakermans‐Kranenburg, M. J., Bosmans, G., & D’Hooge, R. (2026) · Scientific Reports · doi:10.1038/s41598-026-38976-9 · Cited by 1
Taranukhin, A. G., Yamova, L. A., & Chernigovskaya, E. V. (2006) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093006020141 · Cited by 1
Teruyama, R., & Govar, A. A. (2024) · Peptides · doi:10.1016/j.peptides.2024.171283 · Cited by 1
Alonso, G., Brun, O., Ridet, J., Geffard, M., & Chauvet, N. (1995) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(95)00081-x · Cited by 1
Self-citationWegner, I. C., Teuchert, G., & Dawirs, R. R. (1996) · Life Sciences · doi:10.1016/0024-3205(96)00468-7 · Cited by 1
Taranukhin, A. G., Chernigovskaya, E. V., Glazova, M. V., Evteeva, S. E., Yamova, L. A., & Oganesyan, G. A. (2003) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1023/b:joey.0000023493.43210.ff · Cited by 1
Hoyda, T. D. (2010) · QSpace (Queen's University Library) · Cited by 1
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ASSENMACHER, I., & Alonso, G. (1987) · Springer eBooks · doi:10.1007/978-3-642-72886-0_3 · Cited by 1
Los Receptores Dopaminérgicos y la acción renal de la administración central de adrenomedulina
Díaz, E., & Israel, A. L. (2003) · Archivos Venezolanos de Farmacología y Terapéutica
Shioda, S., MUROI, M., & Nakai, Y. (1992) · The Showa University Journal of Medical Sciences · doi:10.15369/sujms1989.4.71
Chernigovskaya, E. V., Taranukhin, A. G., Yamova, L. A., Komissarov, A. B., & Glazova, M. V. (2006) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093006010133
Ochiai, H., & Nakai, Y. (1995) · The Showa University Journal of Medical Sciences · doi:10.15369/sujms1989.7.183
Interaction of the Dopaminergic and Vasopressinergic Systems in Sleep Deprivation in Rats
Oganesyan, G. A., Romanova, I. V., Михрина, А. Л., Paskarenko, N. M., & Kuzik, V. V. (2014) · Neuroscience and Behavioral Physiology · doi:10.1007/s11055-014-9970-x
The Cell Biology of Oxytocin and Vasopressin Cells
Theodosis, D. T., Voisin, D. L., Poulain, D. A., & Tasker, J. G. (2009) · Elsevier eBooks · doi:10.1016/b978-008088783-8.00050-4
Morales, L., Desfilis, E., & Medina, L. M. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.09.632163
Catecholaminergic Brain Stem Regulatory Systems
Björklund, A., & Lindvall, O. (1986) · Comprehensive physiology · doi:10.1002/j.2040-4603.1986.tb00901.x
Govar, A. A., Ghimire, B., Nishimori, K., & Teruyama, R. (2025) · Journal of Neuroendocrinology · doi:10.1111/jne.70124
Ocytocine versus dopamine : l’équilibre délicat entre lien social et addiction
Rappeneau, V., & Díaz, F. C. (2025) · Biologie Aujourd hui · doi:10.1051/jbio/2025012
Circuits neuronaux sous-tendant la régulation émotionnelle par le système ocytocinergique
Goyon, S. (2018) · theses.fr (ABES) · doi:10.70675/c8c9bec0z7b79z4826z862az93b128e1ada6
Hypothalamic supraoptic and paraventricular nuclei
Krabichler, Q., & Grinevich, V. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-24078-2.00012-7
Intrinsic and Synaptic Factors Regulating Mammalian Magnocellular Neurosecretory Neuron Activity
Renaud, L. P. (1988) · Springer eBooks · doi:10.1007/978-1-4684-5502-1_24
Andersen (2000) · doi:10.1002/1098-2396(200008)37:2
Metadata
- Authors
- Buijs, R. M., Geffard, M., Pool, C. W., & Hoorneman, E. M. D.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Buijs, R.M.
- Venue
- Brain Research
- Publisher
- Elsevier BV
- Published
- 1984-12
- Volume
- 323
- Issue
- 1
- Pages
- 65-72
- ISSN
- 0006-8993 (ISSN-L)
- OpenAlex
- W2126473406
- Cited by
- 226
- References
- 31
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 4 · 2023: 2 · 2022: 5 · 2021: 2 · 2018: 4 · 2017: 3 · 2016: 3 · 2015: 1 · 2014: 3 · 2013: 2 · 2012: 4
- FWCI
- 20.68
- Type
- journal article
- Language
- en
- Open access
- green
- pure.knaw.nl
- Locations
- Brain Research (publishedVersion)
- PubMed (publishedVersion)
- KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- dopaminergic innervation, supraoptic nucleus, paraventricular nucleus, hypothalamus, magnocellular neurons, vasopressin release, oxytocin release, suprachiasmatic nucleus, synaptic terminals, dense core vesicles, clear vesicles, ultrastructure
- MeSH terms
- Animals, Dopamine, Immunoenzyme Techniques, Male, Microscopy, Electron, Oxytocin, Paraventricular Hypothalamic Nucleus, Rats, Inbred Strains, Supraoptic Nucleus, Vasopressins, Rats
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