Identification of the vasopressin producing and of the oxytocin producing neurons in the hypothalamic magnocellular neurosecretory system of the rat
Abstract
Immuno-enzyme histochemical investigations showed that, in the magnocellular hypothalamo-hypophysial neurosecretory system of the rat, vasopressin and oxytocin are synthetized in separate neurons. Both the vasopressin neurons and the oxytocin neurons are present in both the supraoptic and the paraventricular nuclei in about the same number. Preferential location of the two kinds of rat neurosecretory neurons is not as obvious as in the bovine hypothalamus. Their perikarya do not show distinct morphological differences. The two kinds of neurosecretory perikarya are the origin of separate vasopressin-containing and oxytocin-containing axons respectively. In the neural lobe, the distribution of the two different types of axons is described.
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Opioids directly inhibit oxytocin secretion in mammals through action in the posterior pituitary and the hypothalamus.
“Opioids directly inhibit OT secretion in mammals through action in the posterior pituitary and the hypothalamus (21, 22).”
From Oxytocin under opioid antagonism leads to supralinear enhancement of social attention (2017) · cites this paper as [21]
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- Authors
- Vandesande, F., & Dierickx, K.
- Affiliations
- Ghent University (BE)
- Venue
- Cell and Tissue Research
- Published
- 1975-12
- Volume
- 164
- Issue
- 2
- Pages
- 153-62
- ISSN
- 0302-766X (ISSN-L)
- 1432-0878
- OpenAlex
- W2055208335
- Cited by
- 496
- References
- 10
- Citations by year
- 2026: 4 · 2025: 2 · 2024: 1 · 2023: 2 · 2022: 5 · 2021: 4 · 2020: 3 · 2019: 4 · 2018: 7 · 2017: 8 · 2016: 2 · 2015: 4 · 2014: 9 · 2013: 2 · 2012: 8
- FWCI
- 56.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Cell and Tissue Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- vasopressin, oxytocin, magnocellular neurons, hypothalamo-hypophysial system, supraoptic nucleus, paraventricular nucleus, neurosecretory cells, axon distribution, neural lobe, rats
- MeSH terms
- Animals, Female, Fluorescent Antibody Technique, Histocytochemistry, Hypothalamo-Hypophyseal System, Male, Neurons, Oxytocin, Paraventricular Hypothalamic Nucleus, Staining and Labeling, Supraoptic Nucleus, Vasopressins, Rats
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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