Toxicity of Light-Exposed HEPES media

Analysis of the cytotoxic effects of light-exposed hepes-containing culture medium

Zigler, J. S., Lepe-Zuniga, J. L., Vistica, B. P., & Gery, I. (1985) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/bf02620943 · Cited by 149 · see citing works

Phototoxicity of N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid-buffered culture media for human leukemic cell lines.

Spierenburg, G. T., Oerlemans, F. T. J. J., van Laarhoven, J. P. R. M., & Bruyn, C. H. M. M. D. (1984) · PubMed · Cited by 43 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H., Radbruch, A., Acs, A., Adam, D., Adam‐Klages, S., Agace, W. W., Aghaeepour, N., Akdiş, M., Allez, M., et al. (2019) · European Journal of Immunology · doi:10.1002/eji.201970107 · Cited by 982 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies *

Cossarizza, A., Chang, H., Radbruch, A., Akdiş, M., Andrä, I., Annunziato, F., Bächer, P., Barnaba, V., Battistini, L., Bauer, W. M., et al. (2017) · European Journal of Immunology · doi:10.1002/eji.201646632 · Cited by 572 · see citing works

A new approach to neural cell culture for long-term studies

Potter, S. M., & DeMarse, T. B. (2001) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(01)00412-5 · Cited by 491 · see citing works

Dependence of the Cyanobacterium Prochlorococcus on Hydrogen Peroxide Scavenging Microbes for Growth at the Ocean's Surface

Morris, J., Johnson, Z. I., Szul, M. J., Keller, M., & Zinser, E. R. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016805 · Cited by 325 · see citing works

Design and Fabrication of Tubular Scaffolds via Direct Writing in a Melt Electrospinning Mode

Brown, T. D., Slotosch, A., Thibaudeau, L., Taubenberger, A. V., Loessner, D., Vaquette, C., Dalton, P. D., & Hutmacher, D. W. (2012) · Biointerphases · doi:10.1007/s13758-011-0013-7 · Cited by 299 · see citing works

Evidence-based Guidelines for Controlling pH in Mammalian Live-Cell Culture Systems

Michl, J., Park, K. C., & Swietach, P. (2019) · Communications Biology · doi:10.1038/s42003-019-0393-7 · Cited by 267 · see citing works

Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems

Müller, D. J., Dumitru, A. C., Giudice, C. L., Gaub, H. E., Hinterdorfer, P., Hummer, G., Yoreo, J. J. D., Dufrêne, Y. F., & Alsteens, D. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00617 · Cited by 263 · see citing works

Comparative stability studies of poly(2-methyl-2-oxazoline) and poly(ethylene glycol) brush coatings

Pidhatika, B., Rodenstein, M., Chen, Y., Rakhmatullina, E., Mühlebach, A., Acikgöz, C., Textor, M., & Konradi, R. (2012) · Biointerphases · doi:10.1007/s13758-011-0001-y · Cited by 251 · see citing works

A global view of protein expression in human cells, tissues, and organs

Pontén, F., Gry, M., Fagerberg, L., Lundberg, E., Asplund, A., Berglund, L., Oksvold, P., Björling, E., Hober, S., Kampf, C., et al. (2009) · Molecular Systems Biology · doi:10.1038/msb.2009.93 · Cited by 222 · see citing works

Optimizing the culture environment in the IVF laboratory: impact of pH and buffer capacity on gamete and embryo quality

Swain, J. E. (2010) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2010.03.012 · Cited by 140 · see citing works

Inertial picobalance reveals fast mass fluctuations in mammalian cells

Martínez-Martín, D., Fläschner, G., Gaub, B. M., Martin, S., Newton, R., Beerli, C., Mercer, J., Gerber, C., & Müller, D. J. (2017) · Nature · doi:10.1038/nature24288 · Cited by 119 · see citing works

Biological pH buffers in IVF: help or hindrance to success

Will, M. A., Clark, N. A., & Swain, J. E. (2011) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-011-9582-0 · Cited by 112 · see citing works

Confocal Microscopy of Living Cells

Dailey, M. E., Manders, E. M. M., Soll, D. R., & Terasaki, M. (2006) · Springer eBooks · doi:10.1007/978-0-387-45524-2_19 · Cited by 86 · see citing works

Chapter 10 Improved methodology for cell culture of human and monkey retinal pigment epithelium

Pfeffer, B. A. (1991) · Progress in Retinal Research · doi:10.1016/0278-4327(91)90015-t · Cited by 85 · see citing works

Polyoxazoline biointerfaces by surface grafting

Morgese, G., & Benetti, E. M. (2016) · European Polymer Journal · doi:10.1016/j.eurpolymj.2016.11.003 · Cited by 83 · see citing works

New pH-buffering system for media utilized during gamete and embryo manipulations for assisted reproduction

Swain, J. E., & Pool, T. B. (2009) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60029-6 · Cited by 75 · see citing works

Mn(II) Oxidation by the Multicopper Oxidase Complex Mnx: A Binuclear Activation Mechanism

Soldatova, A. V., Tao, L., Romano, C. A., Stich, T. A., Casey, W. H., Britt, R. D., Tebo, B. M., & Spiro, T. G. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b02771 · Cited by 70 · see citing works

Combining confocal and atomic force microscopy to quantify single-virus binding to mammalian cell surfaces

Newton, R., Delguste, M., Koehler, M., Dumitru, A. C., Laskowski, P., Müller, D. J., & Alsteens, D. (2017) · Nature Protocols · doi:10.1038/nprot.2017.112 · Cited by 68 · see citing works

Effect of Sodium Bicarbonate on Extracellular pH, Matrix Accumulation, and Morphology of Cultured Articular Chondrocytes

Waldman, S. D., Couto, D. C., Omelon, S. J., & Kandel, R. A. (2004) · Tissue Engineering · doi:10.1089/ten.2004.10.1633 · Cited by 57 · see citing works

Blue Light Increases Neuronal Activity-Regulated Gene Expression in the Absence of Optogenetic Proteins

Tyssowski, K. M., & Gray, J. M. (2019) · eNeuro · doi:10.1523/eneuro.0085-19.2019 · Cited by 56 · see citing works

Plasma‐Driven in Situ Production of Hydrogen Peroxide for Biocatalysis

Yayci, A., Baraibar, Á. G., Krewing, M., Fernández‐Fueyo, E., Hollmann, F., Alcalde, M., Kourist, R., & Bandow, J. E. (2020) · ChemSusChem · doi:10.1002/cssc.201903438 · Cited by 53 · see citing works

Production of hydrogen peroxide in formulated beverages is associated with the presence of ascorbic acid combined with selected redox-active functional ingredients

Bopitiya, D., Christensen, D., Martin, M., Zhang, J., & Bennett, L. E. (2020) · Food Chemistry · doi:10.1016/j.foodchem.2020.127947 · Cited by 52 · see citing works

CO2-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

Forsberg, D., Horn, Z., Tserga, E., Smedler, E., Silberberg, G., Shvarev, Y., Kaila, K., Uhlén, P., & Herlenius, E. (2016) · eLife · doi:10.7554/elife.14170 · Cited by 43 · see citing works

The Glucocorticoid Receptor Is a Critical Regulator of HIV Latency in Human Microglial Cells

Alvarez-Carbonell, D., Ye, F., Ramanath, N., Dobrowolski, C. N., & Karn, J. (2018) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-018-9798-1 · Cited by 39 · see citing works

Light-activated deoxyguanosine: photochemical regulation of peroxidase activity

Lusic, H., Lively, M. O., & Deiters, A. (2008) · Molecular BioSystems · doi:10.1039/b800166a · Cited by 40 · see citing works

Severe disruption of the cytoskeleton and immunologically relevant surface molecules in a human macrophageal cell line in microgravity—Results of an in vitro experiment on board of the Shenzhou-8 space mission

Paulsen, K., Tauber, S., Goelz, N., Simmet, D. M., Engeli, S., Birlem, M., Dumrese, C., Karer, A., Hunziker, S., Biskup, J., et al. (2013) · Acta Astronautica · doi:10.1016/j.actaastro.2013.06.007 · Cited by 39 · see citing works

Continuous hydrogen peroxide production by organic buffers in phytoplankton culture media

Morris, J., & Zinser, E. R. (2013) · Journal of Phycology · doi:10.1111/jpy.12123 · Cited by 37 · see citing works

Superoxide Dismutase 1 Nanoparticles (Nano-SOD1) as a Potential Drug for the Treatment of Inflammatory Eye Diseases

Vaneev, A. N., Kost, O. A., Eremeev, N. L., Валерьевна, Б. О., Alova, A. V., Gorelkin, P. V., Erofeev, A. S., Chesnokova, N. B., Kabanov, A. V., & Klyachko, N. L. (2021) · Biomedicines · doi:10.3390/biomedicines9040396 · Cited by 35 · see citing works

ph drift of “physiological buffers” and culture media used for cell incubation during in vitro studies

Lelong-Rebel, I. H., & Rebel, G. (1998) · Journal of Pharmacological and Toxicological Methods · doi:10.1016/s1056-8719(98)00019-7 · Cited by 34 · see citing works

Incubator-independent cell-culture perfusion platform for continuous long-term microelectrode array electrophysiology and time-lapse imaging

Saalfrank, D., Konduri, A. K., Latifi, S., Habibey, R., Golabchi, A., Martiniuc, A. V., Knoll, A., Ingebrandt, S., & Blau, A. W. (2015) · Royal Society Open Science · doi:10.1098/rsos.150031 · Cited by 31 · see citing works

Experimental and theoretical study of biodirected green synthesis of gold nanoflowers

Jakhmola, A., Vecchione, R., Gentile, F., Profeta, M., Manikas, A. C., Battista, E., Celentano, M., Onesto, V., & Netti, P. A. (2019) · Materials Today Chemistry · doi:10.1016/j.mtchem.2019.100203 · Cited by 28 · see citing works

Zwitterionic buffers preserve ram semen quality more efficiently than TRIS during storage at 15°C

Yániz, J. L., Mateos, J. A., & Santolaria, P. (2010) · Small Ruminant Research · doi:10.1016/j.smallrumres.2010.08.006 · Cited by 27 · see citing works

Cell culture chamber with gas supply for prolonged recording of human neuronal cells on microelectrode array

Kreutzer, J., Ylä‐Outinen, L., Mäki, A.-J., Ristola, M., Narkilahti, S., & Kallio, P. J. (2017) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2017.01.019 · Cited by 25 · see citing works

Toward Best Practices for Controlling Mammalian Cell Culture Environments

Klein, S. G., Steckbauer, A., Alsolami, S. M., Arossa, S., Parry, A. J., Li, M., & Duarte, C. M. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.788808 · Cited by 23 · see citing works

Flow Cytometric Methods for Sperm Assessment

Robles, V., & Martínez‐Pastor, F. (2012) · Methods in molecular biology · doi:10.1007/978-1-62703-038-0_16 · Cited by 22 · see citing works

Case Studies Exemplifying the Transition to Animal Component-free Cell Culture

Weber, T., Wiest, J., Oredsson, S., & Bieback, K. (2022) · Alternatives to Laboratory Animals · doi:10.1177/02611929221117999 · Cited by 21 · see citing works

Effect of Biopsy Location and Size on Proliferative Capacity of Ex Vivo Expanded Conjunctival Tissue

Eidet, J. R., Fostad, I. G., Shatos, M. A., Utheim, T. P., Utheim, Ø. A., Ræder, S., & Dartt, D. A. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.11-8269 · Cited by 15 · see citing works

The determination of oxidation rates and quantum yields during the photocatalytic oxidation of As(III) over TiO2

Heiba, H. F., Bullen, J. C., Kafizas, A., Petit, C., Skinner, S. J., & Weiss, D. J. (2021) · Journal of Photochemistry and Photobiology A Chemistry · doi:10.1016/j.jphotochem.2021.113628 · Cited by 14 · see citing works

Probing Residue-Specific Interactions in the Stabilization of Proteins Using High-Resolution NMR: A Study of Disulfide Bond Compensation

Skinner, A. L., & Laurence, J. S. (2010) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.22055 · Cited by 14 · see citing works

Subcellular Min Oscillations as a Single-Cell Reporter of the Action of Polycations, Protamine, and Gentamicin on Escherichia coli

Downing, B. P. B., Rutenberg, A. D., Touhami, A., & Jericho, M. H. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007285 · Cited by 13 · see citing works

New Buffers to Improve the Quantitative Real-Time Polymerase Chain Reaction

Ahmad, A. I., & Ghasemi, J. B. (2007) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.70164 · Cited by 11 · see citing works

Cyanobacteria cultivation on human urine for nutrients recovery

Canizales, S., Chen, P.-H., Temmink, H., Wijffels, R. H., & Janssen, M. G. J. (2023) · Algal Research · doi:10.1016/j.algal.2023.103064 · Cited by 10 · see citing works

Novel bench-top perfusion system improves functional performance of bioengineered heart muscle

Hecker, L., Khait, L., Radnoti, D., & Birla, R. K. (2009) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2008.09.019 · Cited by 10 · see citing works

Inferences of Carbon Dioxide in Present-Day Cell Culture Systems: An Unacknowledged Problem and Perspectives

Dubey, A. K., Lavanya, L. C., Sadananda, D., Gouthami, K., Elfansu, K., Singh, A., Singh, A. K., & Ak, S. (2021) · Austin Therapeutics · doi:10.26420/austintherapeutics.2021.1033 · Cited by 10 · see citing works

Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteinsPreprint

Tyssowski, K. M., & Gray, J. M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/572370 · Cited by 10 · see citing works

Relevance of Excitable Media Theory and Retinal Spreading Depression Experiments in Preclinical Pharmacological Research

de Lima, V. M. F., & Hanke, W. R. L. (2014) · Current Neuropharmacology · doi:10.2174/1570159x12666140630190800 · Cited by 8 · see citing works

Selective comparison of gelling agents as neural cell culture matrices for long-term microelectrode array electrophysiology

Wilk, N., Habibey, R., Golabchi, A., Latifi, S., Ingebrandt, S., & Blau, A. W. (2016) · OCL · doi:10.1051/ocl/2015068 · Cited by 7 · see citing works

Isolation and in vitro culture of primary cell populations derived from ovarian tissues of the rockfish, Sebastes schlegeli

Ryu, J. H., Kim, H. J., Bae, S. S., Jung, C.-G., & Gong, S. P. (2016) · Fisheries and aquatic sciences · doi:10.1186/s41240-016-0009-9 · Cited by 7 · see citing works

Studies on Culture and Osteogenic Induction of Human Mesenchymal Stem Cells under CO 2 -Independent Conditions

Chen, J., Zhang, C., Feng, Y., Zong, C., Chen, J., Tang, Z., Jia, B., Tong, X., Zheng, Q., & Wang, J. (2013) · Astrobiology · doi:10.1089/ast.2012.0922 · Cited by 7 · see citing works

In Situ Single-Cell Bacterial Imaging Provides Mechanistic Insight into the Photodynamic Action of Photosensitizer-Loaded Hydrogels

Ortega, I. V., Raman, T. Ş., Schulze, A., & Flors, C. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.3c17916 · Cited by 6 · see citing works

Motility flow and growth-cone navigation analysis during in vitro neuronal development by long-term bright-field imaging

Shalev, M. A., Pesce, M., Tilve, S. M., Chieregatti, E., Zalevsky, Z., & Difato, F. (2013) · Journal of Biomedical Optics · doi:10.1117/1.jbo.18.11.111415 · Cited by 6 · see citing works

Hypoxic Cell Death is Reduced by pH Buffering in a Model of Engineered Heart Tissue

Brown, D. A., MacLellan, W. R., Dunn, J., Wu, B. M., & Beygui, R. E. (2008) · Artificial Cells Blood Substitutes and Biotechnology · doi:10.1080/10731190801932090 · Cited by 6 · see citing works

Culture Media in IVF: Decisions for the Laboratory

Swain, J. E., & Pool, T. B. (2012) · Springer eBooks · doi:10.1007/978-1-4419-1780-5_11 · Cited by 4 · see citing works

Min oscillations in bacteria as real-time reporter of environmental challenges at the single-cell level

Ortega, I. V., Viela, F., & Flors, C. (2023) · Open Biology · doi:10.1098/rsob.230020 · Cited by 4 · see citing works

Structural Effects on the Reaction of Singlet Oxygen with Tertiary Amines in Aqueous Solution

Sliwinski, G., Lessard, E. E., & Landino, L. M. (2025) · Oxygen · doi:10.3390/oxygen5040022 · Cited by 3 · see citing works

Probing Peroxisome Dynamics and Biogenesis by Fluorescence Imaging

Jauregui, M., & Kim, P. K. (2014) · Current Protocols in Cell Biology · doi:10.1002/0471143030.cb2109s62 · Cited by 3 · see citing works

Statistical Methodology for the Detection of Small Changes in Distances by EXAFS: Application to the Antimalarial Ruthenoquine

Curis, E., Dubar, F., Nicolis, I., Bénazeth, S., & Biot, C. (2012) · The Journal of Physical Chemistry A · doi:10.1021/jp301811r · Cited by 3 · see citing works

An integrated 3D fluidic device with bubble guidance mechanism for long-term primary and secondary cell recordings on multi-electrode array platform

Konduri, A. K., Deepak, C. P., Purohit, S., & Narayan, K. S. (2020) · Biofabrication · doi:10.1088/1758-5090/aba500 · Cited by 3 · see citing works

Effect of Cell Culture Medium on the Proliferation and Stemness of CD24-/CD44+ Human Breast Cancer Stem Cells

Nadia, Y. F., Syahrani, R. A., Arumsari, S., Sadikin, M., & Wanandi, S. I. (2021) · The Indonesian Biomedical Journal · doi:10.18585/inabj.v13i4.1674 · Cited by 3 · see citing works

Modeling of Diseases of Retinal Ischemia in vitro: Possible Participation of Autocrine Vascular Endothelial Growth Factor Signaling

Yan, Y., He, T., Shen, Y., Chen, X., Diao, B., Li, Z., Zhou, F., & Xing, Y.-Q. (2012) · Ophthalmic Research · doi:10.1159/000343254 · Cited by 2 · see citing works

Structure–Activity Relationships for Tumor-Targeting Gold Nanoparticles

Dreaden, E. C., El‐Sayed, I. H., & El‐Sayed, M. A. (2014) · Frontiers in nanobiomedical research · doi:10.1142/9789814520652_0014 · Cited by 2 · see citing works

Macroscopic Self-Organized Electrochemical Patterns in Excitable Tissue and Irreversible Thermodynamics

de Lima, V. M. F., & Hanke, W. R. L. (2016) · Open Journal of Biophysics · doi:10.4236/ojbiphy.2016.64011 · Cited by 2 · see citing works

CO 2 -Enriched Atmosphere on the Microscope Stage

Diaz, G., Isola, R., Falchi, A. M., & Diana, A. (1999) · BioTechniques · doi:10.2144/99272bm17 · Cited by 2 · see citing works

Optimization of the Acidic–Alkaline Composition of the Incubation Medium for Long-Term and Reversible Cryopreservation of Brain Slices of Nonhibernating Animals

Mokrushin, A. A. (2021) · BIOPHYSICS · doi:10.1134/s0006350921050134 · Cited by 2 · see citing works

Alterations of purine metabolism in mononuclear cells of individuals at risk of developing type I (insulin-dependent) diabetes mellitus

Schäfer, J. H., Jira, T. B., Michaelis, D., & Rjasanowski, I. M. (1989) · Clinica Chimica Acta · doi:10.1016/0009-8981(89)90368-9 · Cited by 2 · see citing works

Development of Serum-Free MediaOptimization of Nutrient Composition and Delivery Format

Jayme, D. W., & Gruber, D. F. (2006) · Elsevier eBooks · doi:10.1016/b978-012164730-8/50006-x · Cited by 2 · see citing works

Surface Functionalization of Biomaterials by Poly(2‐oxazoline)s

Morgese, G., & Benetti, E. M. (2017) · doi:10.1002/9781118967904.ch15 · Cited by 2 · see citing works

Culture Media in IVF: Decisions for the Laboratory

Swain, J. E. (2019) · Springer eBooks · doi:10.1007/978-3-319-43011-9_12 · Cited by 1 · see citing works

Culture Media in IVF: Decisions for the Laboratory

Swain, J. E., & Pool, T. B. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8376-2_5 · Cited by 1 · see citing works

Biological Specimen Preparation

Sanderson, J. (2019) · doi:10.1002/9781118696736.ch28 · Cited by 1 · see citing works

The effects of UV-A light in indirect irradiation on cultures of bovine lens epithelium

Mayer, U. M., Klinge, H., & Radlmeier, M. (1998) · Documenta ophthalmologica. Proceedings series · doi:10.1007/978-94-011-5137-5_12

Towards harmonization of solutions used for cystic fibrosis diagnosis by nasal potential difference measurements: A formulation approach with CHESS® software

Yayé, H. S., Caudron, É., Sermet‐Gaudelus, I., Nicolis, I., Prognon, P., & Pradeau, D. (2021) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2021.05.002

Evaluation of Cell Lysis Techniques for Direct Amplification of Sexual Assault Samples

Schellhammer, S. K. (2021) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/1gvw-rb27

Further Reading

Hibbs, A. R. (2004) · Springer eBooks · doi:10.1007/978-0-306-48565-7_15

ICSI media buffers: is there room for improvement?

Campos, G., & Nel‐Themaat, L. (2026) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-026-03994-z

Analysis of the cytotoxic effects of light-exposed hepes-containing culture medium

Zigler, J. S., Lepe-Zuniga, J. L., Vistica, B. P., & Gery, I. (1985) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/bf02620943 · Cited by 149 · see citing works

Cells in Culture in Toxicity Testing: A Review

Rees, K. (1980) · Journal of the Royal Society of Medicine · doi:10.1177/014107688007300409 · Cited by 20 · see citing works

"Let there be light". A study of phototoxicity.

Goldberg, R. E., & Magargal, L. E. (1985) · PubMed

Toxicity of Pyelographic Media

&NA; (1920) · The American Journal of the Medical Sciences · doi:10.1097/00000441-192008000-00045

Phototoxicity of N-2-hydroxyethylpiperazine-N'-2-ethanesulfonic acid-buffered culture media for human leukemic cell lines.

Spierenburg, G. T., Oerlemans, F. T. J. J., van Laarhoven, J. P. R. M., & Bruyn, C. H. M. M. D. (1984) · PubMed · Cited by 43 · see citing works