Studies in prebiotic synthesis

Mechanism of ε15 conversion studied with bacteriophage mutants

Bray, D., & Robbins, P. W. (1967) · Journal of Molecular Biology · doi:10.1016/s0022-2836(67)80037-8 · Cited by 280

Cyanoacetylene in Prebiotic Synthesis

Sanchez, R. A., Ferris, J. P., & Orgel, L. E. (1966) · Science · doi:10.1126/science.154.3750.784 · Cited by 270

Prebiotic Synthesis of Polypeptides by Heterogeneous Polycondensation of Amino-acid Adenylates

Paecht‐Horowitz, M., BERGER, J., & Katchalsky, A. (1970) · Nature · doi:10.1038/228636a0 · Cited by 266

Studies in prebiotic synthesis

Ferris, J. P., Sanchez, R. A., & Orgel, L. E. (1968) · Journal of Molecular Biology · doi:10.1016/0022-2836(68)90314-8 · Cited by 253

Studies in prebiotic synthesis

Sanchez, R. A., & Orgel, L. E. (1970) · Journal of Molecular Biology · doi:10.1016/0022-2836(70)90320-7 · Cited by 250

Urea-Inorganic Phosphate Mixtures as Prebiotic Phosphorylating Agents

Lohrmann, R., & Orgel, L. E. (1971) · Science · doi:10.1126/science.171.3970.490 · Cited by 245

Untitled work

Kimball (1962) · doi:10.1016/0003-9861(62)90412-5 · Cited by 230

Synthesis of Complex Organic Compounds from Simple Precursors: Formation of Amino-Acids, Amino-Acid Polymers, Fatty Acids and Purines from Ammonium Cyanide

LOWE, C. U., REES, M. W., & MARKHAM, R. (1963) · Nature · doi:10.1038/199219a0 · Cited by 208

Synthesis of Adenosine Triphosphate Under Possible Primitive Earth Conditions

Ponnamperuma, C., Sagan, C., & Mariner, R. (1963) · Nature · doi:10.1038/199222a0 · Cited by 172

An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide1

Ferris, J. P., & Orgel, L. E. (1966) · Journal of the American Chemical Society · doi:10.1021/ja00957a050 · Cited by 160

Application of the Mars Organic Analyzer to Nucleobase and Amine Biomarker Detection

Skelley, A., Cleaves, H., Jayarajah, C. N., Bada, J. L., & Mathies, R. (2006) · Astrobiology · doi:10.1089/ast.2006.6.824 · Cited by 33

One Among Millions: The Chemical Space of Nucleic Acid-Like Molecules

Cleaves, H. J., Butch, C. J., Burger, P. B., Goodwin, J. T., & Meringer, M. (2019) · Journal of Chemical Information and Modeling · doi:10.1021/acs.jcim.9b00632 · Cited by 39

Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA

Housh, K., Jha, J. S., Haldar, T., Amin, S. B. M., Islam, T., Wallace, A., Gomina, A., Guo, X., Nel, C., Wyatt, J. W., et al. (2020) · DNA repair · doi:10.1016/j.dnarep.2020.103029 · Cited by 38

Synthesis of Adenine from HCN Tetramer and Ammonium Formate

Hill, A. R., & Orgel, L. E. (2002) · Origins of Life and Evolution of Biospheres · doi:10.1023/a:1016070723772 · Cited by 38

Prebiotic syntheses of vitamin coenzymes: II. Pantoic acid, pantothenic acid, and the composition of coenzyme A

Miller, S., & Schlesinger, G. (1993) · Journal of Molecular Evolution · doi:10.1007/bf00182178 · Cited by 33

Conversion of Biosynthetic Precursors of RNA to Those of DNA by Photoredox Chemistry

Ritson, D. J., & Sutherland, J. D. (2014) · Journal of Molecular Evolution · doi:10.1007/s00239-014-9617-0 · Cited by 34

The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine

Michaelian, K. (2021) · Entropy · doi:10.3390/e23020217 · Cited by 32

Synthesis of RNA Nucleotides in Plausible Prebiotic Conditions from ab Initio Computer Simulations

Pérez-Villa, A., Saitta, A. M., Georgelin, T., Lambert, J., Guyot, F., Maurel, M., & Pietrucci, F. (2018) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.8b02077 · Cited by 33

Photosynthesis and Photo-Stability of Nucleic Acids in Prebiotic Extraterrestrial Environments

Sandford, S. A., Bera, P. P., Lee, T. J., Materese, C. K., & Nuevo, M. (2014) · Topics in current chemistry · doi:10.1007/128_2013_499 · Cited by 33

CH4/N2/H2 spark hydrophilic tholins: A systematic approach to the characterization of tholins

Ruiz‐Bermejo, M., Menor-Salván, C. A., Mateo‐Martí, E., Osuna‐Esteban, S., Martín-Gago, J. Á., & Veintemillas-Verdaguer, S. (2008) · Icarus · doi:10.1016/j.icarus.2008.07.008 · Cited by 33

Synthesis of information-carrying polymers of mixed sequences from double stranded short deoxynucleotides

Taran, O., Thoennessen, O., Achilles, K., & von Kiedrowski, G. (2010) · Journal of Systems Chemistry · doi:10.1186/1759-2208-1-9 · Cited by 31

A ribonucleopeptide world at the origin of life

Saad, N. Y. (2017) · Journal of Systematics and Evolution · doi:10.1111/jse.12287 · Cited by 33

Prebiotic Routes to Nucleosides: A Quantum Chemical Insight into the Energetics of the Multistep Reaction Pathways

Šponer, J. E., Šponer, J., & Fuentes‐Cabrera, M. (2010) · Chemistry - A European Journal · doi:10.1002/chem.201002057 · Cited by 32

Deposition of Aminomalononitrile-Based Films: Kinetics, Chemistry, and Morphology

Toh, R. J., Evans, R. A., Thissen, H. W., Voelcker, N. H., d’Ischia, M., & Ball, V. (2019) · Langmuir · doi:10.1021/acs.langmuir.9b01497 · Cited by 30

Chemical structure of a prebiotic analog of adenosine

Maurel, M., & Convert, O. (1990) · Origins of Life and Evolution of Biospheres · doi:10.1007/bf01808058 · Cited by 30

Tidal chain reaction and the origin of replicating biopolymers

Lathe, R. (2005) · International Journal of Astrobiology · doi:10.1017/s1473550405002314 · Cited by 32

Structural Phylogenomics Reveals Gradual Evolutionary Replacement of Abiotic Chemistries by Protein Enzymes in Purine Metabolism

Caetano-Anollés, K., & Caetano‐Anollés, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059300 · Cited by 28

The Proteinoid Theory of the Origin of Life and Competing Ideas

Fox, S. W. (1974) · The American Biology Teacher · doi:10.2307/4444705 · Cited by 28

Activation of glycine by ATP, a divalent cation, and proteinoid microspheres

Ryan, J. W., & Fox, S. W. (1973) · Biosystems · doi:10.1016/0303-2647(73)90002-6 · Cited by 28

Origin of life: Consideration of alternatives to proteins and nucleic acids

Nelsestuen, G. L. (1980) · Journal of Molecular Evolution · doi:10.1007/bf01732583 · Cited by 28

Synthesis of barbituric acid containing nucleotides and their implications for the origin of primitive informational polymers

Mungi, C. V., Singh, S. K., Chugh, J., & Rajamani, S. (2016) · Physical Chemistry Chemical Physics · doi:10.1039/c6cp00686h · Cited by 27

Quantitative polyphosphate-induced “prebiotic” peptide formation in H2O by addition of certain azoles and ions

Rabinowitz, J., & Hampai, A. (1985) · Journal of Molecular Evolution · doi:10.1007/bf02100094 · Cited by 26

RNA in evolution: a review

Maurel, M. (1992) · Journal of Evolutionary Biology · doi:10.1046/j.1420-9101.1992.5020173.x · Cited by 26

Genetic Pathways Regulating Glutamate Levels in Retinal Müller Cells

Jablonski, M. M., Freeman-Anderson, N. E., Orr, W. E., Templeton, J. P., Lu, L., Williams, R. W., & Geisert, E. E. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0277-1 · Cited by 25

Synthesis, Structure, Spectroscopic Properties, and Electrochemistry of Rare Earth Sandwich Compounds with Mixed 2,3-Naphthalocyaninato and Octaethylporphyrinato Ligands

Jiang, J., Bian, Y., Furuya, F., Liu, W., Choi, M. T. M., Kobayashi, N., Li, H., Yang, Q., Mak, T. C. W., & Ng, D. K. P. (2001) · Chemistry - A European Journal · doi:10.1002/1521-3765(20011203)7:23 · Cited by 106

Ribonucleotide reduction and the possible role of cobalamin in evolution

Dickman, S. R. (1977) · Journal of Molecular Evolution · doi:10.1007/bf01764600 · Cited by 24

Direct Prebiotic Pathway to DNA Nucleosides

Teichert, J. S., Kruse, F. M., & Trapp, O. (2019) · Angewandte Chemie · doi:10.1002/ange.201903400 · Cited by 25

Modeling the interactions between peptide functions and Sr2+: formamide–Sr2+ reactions in the gas phase

Eizaguirre, A., Mó, O., Yáñez, M., & Salpin, J. (2011) · Physical Chemistry Chemical Physics · doi:10.1039/c1cp21578g · Cited by 22

RNA Catalysis, Thermodynamics and the Origin of Life

Scott, W., Szöke, A., Blaustein, J., O’Rourke, S. M., & Robertson, M. P. (2014) · Life · doi:10.3390/life4020131 · Cited by 21

Comments on `Concentration by Evaporation and the Prebiotic Synthesis of Cytosine'

Shapiro, R. (2002) · Origins of Life and Evolution of Biospheres · doi:10.1023/a:1016582308525 · Cited by 23

Possible Ribose Synthesis in Carbonaceous Planetesimals

Paschek, K., Kohler, K., Pearce, B. K. D., Lange, K., Henning, T. K., Trapp, O., Pudritz, R. E., & Semenov, D. A. (2022) · Life · doi:10.3390/life12030404 · Cited by 24

A Chemical Engineering Perspective on the Origins of Life

Grover, M. A., He, C., Hsieh, M.-C., & Yu, S. (2015) · Processes · doi:10.3390/pr3020309 · Cited by 22

Role of Ferrocyanides in the Prebiotic Synthesis of α-Amino Acids

Ruiz‐Bermejo, M., Osuna‐Esteban, S., & Zorzano, M. (2013) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-013-9336-3 · Cited by 20

Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments

Janicki, M. J., Roberts, S. J., Šponer, J., Powner, M. W., Góra, R. W., & Szabla, R. (2018) · Chemical Communications · doi:10.1039/c8cc07343k · Cited by 20

Was RNA the First Genetic Polymer?

Orgel, L. E. (1989) · Springer eBooks · doi:10.1007/978-1-4684-5664-6_20 · Cited by 20

Prebiotic Chemistry: The Role of Trimetaphosphate in Prebiotic Chemical Evolution

Gan, D., Ying, J.-X., & Zhao, Y. (2022) · Frontiers in Chemistry · doi:10.3389/fchem.2022.941228 · Cited by 18

Synthesis and catalytic activity of adenine containing polyamines

Décout, J., Vergne, J., & Maurel, M. (1995) · Macromolecular Chemistry and Physics · doi:10.1002/macp.1995.021960814 · Cited by 19

Chapter 4: A Geological and Chemical Context for the Origins of Life on Early Earth

Rodriguez, L. E., Altair, T., Hermis, N. Y., Jia, T. Z., Roche, T. P., Steller, L. H., & Weber, J. M. (2024) · Astrobiology · doi:10.1089/ast.2021.0139 · Cited by 20

The Reactions of Nitrogen Heterocycles with Acrolein: Scope and Prebiotic Significance

Cleaves, H. J. (2002) · Astrobiology · doi:10.1089/153110702762470509 · Cited by 18

5. Prebiotic Chemistry – Biochemistry – Emergence of Life (4.4–2 Ga)

Pascal, R., Boiteau, L., Forterre, P., Gargaud, M., Lazcano, A., López‐García, P., Maurel, M., Moreira, D., Peretó, J. G., Prieur, D., et al. (2006) · Earth Moon and Planets · doi:10.1007/s11038-006-9089-3 · Cited by 20

Chemical Evolution of Antivirals Against Enterovirus D68 through Protein‐Templated Knoevenagel Reactions

Tauber, C., Wamser, R., Arkona, C., Tügend, M., Aziz, U. B. A., Pach, S., Schulz, R., Jochmans, D., Wolber, G., Neyts, J. H., et al. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202102074 · Cited by 17

Phosphoribosyl Pyrophosphate: A Molecular Vestige of the Origin of Life on Minerals

Akouche, M., Jaber, M., Maurel, M., Lambert, J., & Georgelin, T. (2017) · Angewandte Chemie · doi:10.1002/ange.201702633 · Cited by 17

A Plausible Prebiotic Path to Nucleosides: Ribosides and Related Aldosides Generated from Ribulose, Fructose, and Similar Abiotic Precursors

Roche, T. P., Fialho, D. M., Menor-Salván, C. A., Krishnamurthy, R., Schuster, G. B., & Hud, N. V. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202203036 · Cited by 17

Drawbacks of the ancient RNA-based life-like system under primitive earth conditions

Kawamura, K. (2012) · Biochimie · doi:10.1016/j.biochi.2012.02.017 · Cited by 18

227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?

Cleaves, H. J., Meringer, M., & Goodwin, J. T. (2015) · Astrobiology · doi:10.1089/ast.2014.1213 · Cited by 17

Searching for Possible Ancestors of RNA: The Self-Assembly Hypothesis for the Origin of Proto-RNA

Cafferty, B. J., Fialho, D. M., & Hud, N. V. (2018) · Nucleic acids and molecular biology · doi:10.1007/978-3-319-93584-3_5 · Cited by 18

Uric Acid: Chemistry and Synthesis

Hitchings, G. H. (1978) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-66867-8_1 · Cited by 17

Studies of nucleic acid-like polymers as catalysts

Maurel, M., & D�cout, J.-L. (1992) · Journal of Molecular Evolution · doi:10.1007/bf00178594 · Cited by 17

Lipid-Assisted Polymerization of Nucleotides

Olasagasti, F., & Rajamani, S. (2019) · Life · doi:10.3390/life9040083 · Cited by 15

Electron impact rotationally elastic total cross section for formamide

Vinodkumar, M., Limbachiya, C. G., Desai, H., & Vinodkumar, P. C. (2014) · Journal of Applied Physics · doi:10.1063/1.4896485 · Cited by 16

Possible prebiotic catalysts formed from adenine and aldehyde

Vergne, J., Dumas, L., Décout, J., & Maurel, M. (2000) · Planetary and Space Science · doi:10.1016/s0032-0633(00)00087-8 · Cited by 17

Can an Imidazole Be Formed from an Alanyl-Seryl-Glycine Tripeptide under Possible Prebiotic Conditions?

Vázquez-Salazar, A., Tan, G. K., Stockton, A. M., Fani, R., Becerra, A., & Lazcano, A. (2016) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-016-9525-y · Cited by 16

PHOTOCHEMICAL SYNTHESIS OF ATP: PROTOMEMBRANES AND PROTOMETABOLISM**Aided by the Robert Sterling Clark Foundation, Mr. David Rose, and Grant NGR 10-007-008 of the National Aeronautics and Space Administration. Contribution No. 320 of the Institute for Molecular and Cellular Evolution.

Fox, S. W., Adachi, T., Stillwell, W. H., Ishima, Y., & Baumann, G. (1978) · Elsevier eBooks · doi:10.1016/b978-0-12-207650-3.50007-x · Cited by 16

Theoretical studies of the mechanism of 2-aminooxazole formation under prebiotically plausible conditions

Szabla, R., Šponer, J. E., Šponer, J., & Góra, R. W. (2013) · Physical Chemistry Chemical Physics · doi:10.1039/c3cp50320h · Cited by 15

Purine Biosynthetic Intermediate-Containing Ribose-Phosphate Polymers as Evolutionary Precursors to RNA

Bernhardt, H. S., & Sandwick, R. K. (2014) · Journal of Molecular Evolution · doi:10.1007/s00239-014-9640-1 · Cited by 14

Cavitation as a plausible driving force for the prebiotic formation of N9 purine nucleosides

Patehebieke, Y., Zhao, Z.-R., Wang, S., Xu, H.-X., Chen, Q.-Q., & Wang, X. (2021) · Cell Reports Physical Science · doi:10.1016/j.xcrp.2021.100375 · Cited by 15

The Prebiotic Synthesis of Organic Compounds on the Early Earth

Miller, S. L. (1993) · Topics in geobiology · doi:10.1007/978-1-4615-2890-6_30 · Cited by 15

Prebiotic Glycosylation of Uracil with Electron-Donating Substituents

Kim, H., & Benner, S. A. (2015) · Astrobiology · doi:10.1089/ast.2014.1264 · Cited by 14

Novel and unusual nucleosides as drugs

Kolb, V. M. (1997) · Birkhäuser Basel eBooks · doi:10.1007/978-3-0348-8861-5_8 · Cited by 14

Abiogenic synthesis of nucleotides on the surface of small space bodies with high energy particles

Simakov, M. B., Kuzicheva, E. A., Antropov, A. E., & Dodonova, N. Y. (2002) · Advances in Space Research · doi:10.1016/s0273-1177(02)00510-0 · Cited by 13

Coacervate Droplets, Proteinoid Microspheres, and the Genetic Apparatus

Fox, S. W. (1974) · Springer eBooks · doi:10.1007/978-1-4684-2115-6_13 · Cited by 13

The Prebiotic Synthesis of Organic Molecules and Polymers

Miller, S. L. (1994) · Advances in chemical physics · doi:10.1002/9780470142790.ch7 · Cited by 13

A ribonucleotide Origin for Life – Fluctuation and Near-ideal Reactions

Yarus, M. (2013) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-013-9325-6 · Cited by 13

Walking over 4 Gya: Chemical Evolution from Photochemistry to Mineral and Organic Chemistries Leading to an RNA World

Kawamura, K., & Maurel, M. (2017) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-017-9537-2 · Cited by 14

Could Purines Be Formed from Cyanamide and Cyanoacetylene in a Prebiotic Earth Environment?

Kaur, S., Ohri, A., & Sharma, P. (2019) · ACS Omega · doi:10.1021/acsomega.9b01169 · Cited by 13

An experimental study of the thermolysis of hydrogen cyanide: the role of hydrothermal systems in chemical evolution

Villafañe-Barajas, S. A., Colín-García, M., Negrón-Mendoza, A., & Ruiz‐Bermejo, M. (2020) · International Journal of Astrobiology · doi:10.1017/s1473550420000142 · Cited by 13

Magnesium pyrophosphates in enzyme mimics of nucleotide synthases and kinases and in their prebiotic chemistry

Gopinath, P., Ramalingam, V., & Breslow, R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1516239112 · Cited by 12

N6-substituted adenine derivatives and RNA primitive catalysts

Décout, J., & Maurel, M. (1993) · Origins of Life and Evolution of Biospheres · doi:10.1007/bf01582080 · Cited by 13

Prebiotic Synthesis of ATP: A Terrestrial Volcanism-Dependent Pathway

Chu, X., & Zhang, H. (2023) · Life · doi:10.3390/life13030731 · Cited by 11

Nicht‐kanonische RNA‐Nukleoside als molekulare Fossilien einer frühen Erde – Generierung durch präbiotische Methylierungen und Carbamoylierungen

Schneider, C., Becker, S. M., Okamura, H., Crisp, A. L., Amatov, T., Stadlmeier, M., & Carell, T. (2018) · Angewandte Chemie · doi:10.1002/ange.201801919 · Cited by 11

Meteorite-catalyzed intermolecular trans -glycosylation produces nucleosides under proton beam irradiation

Bizzarri, B. M., Fanelli, A., Kapralov, M. I., Krasavin, E. A., & Saladino, R. (2021) · RSC Advances · doi:10.1039/d1ra02379a · Cited by 11

The Prebiotic Chemistry of Alternative Nucleic Acids

Cleaves, H. J., & Bada, J. L. (2012) · Cellular origin and life in extreme habitats · doi:10.1007/978-94-007-2941-4_1 · Cited by 12

Question 5: On the Chemical Reality of the RNA World

Lucrezia, D. D., Anella, F., & Chiarabelli, C. (2007) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-007-9098-x · Cited by 11

Abiotic Ribonucleoside Formation in Aqueous Microdroplets: Mechanistic Exploration, Acidity, and Electric Field Effects

Piejko, M., Ramos, J. E. A., Moran, J., & Stuyver, T. (2025) · ChemistryEurope · doi:10.1002/ceur.202400093 · Cited by 10

An approach to the generation of simple analogues of the antitumour agent spicamycinThis is one of a number of contributions from the current members of the Dyson Perrins Laboratory to mark the end of almost 90 years of organic chemistry research in that building, as all its current academic staff move across South Parks Road to a new purpose-built laboratory.

Mons, S., & Fleet, G. W. J. (2003) · Organic & Biomolecular Chemistry · doi:10.1039/b307795k · Cited by 10

Origin of life: A hypothesis for the origin of adaptor-mediated ordered synthesis of proteins and an explanation for the choice of terminating codons in the genetic code

Balasubramanian, R. (1982) · Biosystems · doi:10.1016/0303-2647(82)90023-5 · Cited by 10

Origin of Life: RNA World Versus Autocatalytic Anabolist

Wächtershäuser, G. (2013) · Springer eBooks · doi:10.1007/978-3-642-30194-0_12 · Cited by 9

An Approach to Prebiotic Synthesis of α-Oligoribonucleotides and Description of Their Properties: Selective Advantage of β-RNA over α-RNA

Sawai, H., Itoh, T., Kokaji, K., & Shinozuka, K. (1997) · Journal of Molecular Evolution · doi:10.1007/pl00006222 · Cited by 9

The RNA World: Hypotheses, Facts and Experimental Results

Maurel, M., & Haenni, A. (2005) · Advances in astrobiology and biogeophysics · doi:10.1007/10913406_17 · Cited by 8

The prebiotic chemistry of nucleotides

Ferris, J. P., Yanagawa, H., & Hagan, W. J. (1984) · Origins of Life and Evolution of Biospheres · doi:10.1007/bf00933645 · Cited by 8

The Use of Ascorbate as an Oxidation Inhibitor in Prebiotic Amino Acid Synthesis: A Cautionary Note

Kuwahara, H., Eto, M., Kawamoto, Y., Kurihara, H., Kaneko, T., Obayashi, Y., & Kobayashi, K. (2012) · Origins of Life and Evolution of Biospheres · doi:10.1007/s11084-012-9296-z · Cited by 10

CHEMICAL EVOLUTION: AN APPROACH FROM RADIATION CHEMISTRY

Negrón-Mendoza, A., Ramos-Bernal, S., Colín-García, M., & Heredia, A. (2016) · RAD Association Journal · doi:10.21175/radj.2016.03.030 · Cited by 8

Prebiotic Synthesis of Bioorganic Compounds by Simulation Experiments

Kobayashi, K. (2019) · Springer eBooks · doi:10.1007/978-981-13-3639-3_4 · Cited by 9

Polymer phosphorylases: clues to the emergence of non-replicative and replicative polymers

Freire, M. Á. (2011) · Theory in Biosciences · doi:10.1007/s12064-011-0131-2 · Cited by 8

Chemical Evolution in the Early Earth

Negrón-Mendoza, A., & Ramos-Bernal, S. (2000) · Springer eBooks · doi:10.1007/978-94-011-4313-4_6 · Cited by 8

The Possible Role of Cyclic Pentacoordinate Phosphorus Intermediates in the Origin and Evolution of Life. are Phosphoric Anhydride and Trimetaphosphates Prebiotic Reagents?

Baccolini, G. (2015) · Phosphorus, sulfur, and silicon and the related elements · doi:10.1080/10426507.2015.1083569 · Cited by 8

Formation of adenosine from adenine and ribose under conditions of repeated wetting and drying in the presence of clay minerals

Hashizume, H., Theng, B. K. G., van der Gaast, S., & Fujii, K. (2019) · Geochimica et Cosmochimica Acta · doi:10.1016/j.gca.2019.06.040 · Cited by 7

H-Bond activated glycosylation of nucleobases: implications for prebiotic nucleoside synthesis

Singh, P., Singh, A., Kaur, J., & Hölzer, W. (2013) · RSC Advances · doi:10.1039/c3ra44776f · Cited by 8

A Prebiotic Ribosylation of Pyrimidine Nucleobases Enabled by Metal Cations and Clay Minerals

Chen, Q.-Q., Zhao, Z.-R., & Wang, X. (2021) · Life · doi:10.3390/life11121381 · Cited by 7

Precipitation of polynucleotides from acidic solutions. Effects of base composition and ionic strength

Zimmerman, S. B. (1973) · Biochemistry · doi:10.1021/bi00739a023 · Cited by 7

Errors and Alternatives in Prebiotic Replication and Catalysis

Ninio, J. (2007) · Chemistry & Biodiversity · doi:10.1002/cbdv.200790054 · Cited by 6

A Missing Prebiotic Link: Discovery of a Plausible Synthesis of Pyrimidine Nucleotides

Switzer, C. (2009) · ChemBioChem · doi:10.1002/cbic.200900516 · Cited by 6

Looking Beyond the RNA Structural Neighborhood for Potentially Primordial Genetic Systems

Sutherland, J. D. (2007) · Angewandte Chemie International Edition · doi:10.1002/anie.200604374 · Cited by 6

Prebiotic Chemistry — Biochemistry — Emergence of Life (4.4-2 Ga)

Pascal, R., Boiteau, L., Forterre, P., Gargaud, M., Lazcano, A., López‐García, P., Moreira, D., Maurel, M., Peretó, J. G., Prieur, D., et al. (2007) · Springer eBooks · doi:10.1007/978-0-387-45083-4_5 · Cited by 7

A Novel Synthesis of Biomolecular Precursors

Saladino, R., Crestini, C., Ciciriello, F., Costanzo, G., Negri, R., & Mauro, E. D. (2004) · Springer eBooks · doi:10.1007/1-4020-2305-7_16 · Cited by 6

Distribution of extraterrestrial nucleobases, other N-heterocycles, and their precursors in a sample from asteroid Bennu

Oba, Y., Koga, T., Takano, Y., Naraoka, H., Hirakawa, Y., SUNAMI, S., Furukawa, Y., Yamazaki, T., Tomaru, T., Dworkin, J. P., et al. (2026) · Communications Chemistry · doi:10.1038/s42004-026-01966-z · Cited by 6

Regioselective ribonucleoside synthesis through Ti-catalysed ribosylation of nucleobases

Chen, Q.-Q., Zhao, Z.-R., Patehebieke, Y., & Wang, X. (2023) · Nature Synthesis · doi:10.1038/s44160-022-00206-1 · Cited by 6

Distinguishing Biotic vs. Abiotic Origins of ‘Bio’signatures: Clues from Messy Prebiotic Chemistry for Detection of Life in the Universe

Bapat, N. V., & Rajamani, S. (2023) · Life · doi:10.3390/life13030766 · Cited by 6

A new and potentially prebiotic α-cytidine derivative

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