A controlled family study of anorexia nervosa
Abstract
A family study of eating disorders in first and second-degree relatives of anorexia nervosa and nonanorexic psychiatrically ill control probands found increased rates of anorexia-nervosa, bulimia nervosa, and subclinical anorexia nervosa in relatives of anorexic probands. The pattern of familial clustering suggests that these disorders may represent variable expressions of a common underlying psychopathology, although restricter and bulimic subforms of eating disorder may segregate within families. Implications of these findings for understanding factors important to the pathogenesis and subclassification of eating disorders are discussed.
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Eating disorders, such as anorexia nervosa, have a significant genetic component.
“Eating disorders, such as anorexia nervosa (AN), have a significant genetic component.”
From Evidence for a Susceptibility Gene for Anorexia Nervosa on Chromosome 1 (2002) · cites this paper as Strober et al. 1985
Family studies have shown significantly increased prevalence of eating disorders in relatives of probands with anorexia nervosa compared to relatives of control probands.
“Family studies have shown significantly increased prevalence of eating disorders in relatives of probands with AN, compared to relatives of control probands (Gershon et al. 1983; Strober et al. 1985; Hudson et al. 1987; Lilenfeld et al. 1998), thereby providing evidence for the familiality of eating disorders.”
From Evidence for a Susceptibility Gene for Anorexia Nervosa on Chromosome 1 (2002) · cites this paper as Strober et al. 1985
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Symptom fluctuation in eating disorders: correlates of diagnostic crossover
Tozzi, F., Thornton, L. M., Klump, K. L., Fichter, M. M., Halmi, K. A., Kaplan, A. S., Strober, M., Woodside, D. B., Crow, S., Mitchell, J., et al. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.4.732 · Cited by 317 · see citing works
Self-citationHeritability of binge-eating and broadly defined bulimia nervosa
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Evidence for a Susceptibility Gene for Anorexia Nervosa on Chromosome 1
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A controlled family history study of bulimia
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A search for susceptibility loci for anorexia nervosa: methods and sample description
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Self-citation
- Authors
- Strober, M., Morrell, W., Burroughs, J., Salkin, B., & Jacobs, C.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Strober, Michael
- Venue
- Journal of Psychiatric Research
- Publisher
- Elsevier BV
- Published
- 1985
- Volume
- 19
- Issue
- 2-3
- Pages
- 239-246
- ISSN
- 0022-3956 (ISSN-L)
- OpenAlex
- W2056095150
- Cited by
- 134
- References
- 15
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 3 · 2014: 3 · 2013: 1 · 2012: 1
- FWCI
- 6.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychiatric Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- anorexia nervosa, bulimia nervosa, eating disorders, familial aggregation, first-degree relatives, second-degree relatives, genetic susceptibility, pathogenesis
- MeSH terms
- Adolescent, Anorexia Nervosa, Family, Female, Humans, Hyperphagia, Risk, Social Environment
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