Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor.
Open accessAbstract
Mutation frequency decline (MFD) is the rapid decrease in the frequency of certain induced nonsense suppressor mutations occurring when protein synthesis is transiently inhibited immediately after irradiation. MFD is abolished by mutations in the uvrA, -B, or -C genes, which prevent excision repair, or by a mfd mutation, which reduces the rate of excision but does not affect survival. Using an in vitro repair synthesis assay we found that although wild-type cells repair the transcribed (template) strand preferentially, mfd- cells are incapable of strand-specific repair. The deficiency in strand-selective repair of mfd- cell extract was corrected by adding highly purified "transcription-repair coupling factor" to the reaction mixture. We conclude that mfd is, most likely, the gene encoding the transcription-repair coupling factor.
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Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli
Witkin, E. M. (1976) · Bacteriological Reviews · doi:10.1128/br.40.4.869-907.1976 · Cited by 1,862 · see citing works
Self-citationMELLON, I. (1987) · Cell · doi:10.1016/0092-8674(87)90151-6 · Cited by 1,228 · see citing works
Sancar, A., & Rupp, W. D. (1983) · Cell · doi:10.1016/0092-8674(83)90354-9 · Cited by 627 · see citing works
Self-citationMellon, I., & Hanawalt, P. C. (1989) · Nature · doi:10.1038/342095a0 · Cited by 573 · see citing works
Venema, J., Mullenders, L. H. F., Natarajan, A. T., van Zeeland, A. A., & Mayne, L. V. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.12.4707 · Cited by 552 · see citing works
Methyl-directed repair of DNA base-pair mismatches in vitro.
Lu, A.-L., Clark, S., & Modrich, P. L. (1983) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.80.15.4639 · Cited by 340 · see citing works
ULTRAVIOLET-INDUCED MUTATION AND DNA REPAIR
Witkin, E. M. (1969) · Annual Review of Microbiology · doi:10.1146/annurev.mi.23.100169.002415 · Cited by 340 · see citing works
Self-citationRadiation-Induced Mutations and Their Repair
Witkin, E. M. (1966) · Science · doi:10.1126/science.152.3727.1345 · Cited by 331 · see citing works
Self-citationTime, Temperature, and Protein Synthesis: A Study of Ultraviolet-Induced Mutation in BacteriaPreprint
Witkin, E. M. (1956) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1956.021.01.011 · Cited by 308 · see citing works
Self-citationMatson, S. W. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67506-4 · Cited by 213 · see citing works
Bridges, B. A., Dennis, R. E., & Munson, R. J. (1967) · Genetics · doi:10.1093/genetics/57.4.897 · Cited by 189 · see citing works
Selby, C. P., & Sancar, A. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)45364-6 · Cited by 171 · see citing works
Self-citationDNA Strand Specificity for UV-Induced Mutations in Mammalian Cells
Vrieling, H., Rooijen, M. L. V., Groen, N. A., Zdzienicka, M. Z., Simons, J. W. I. M., Lohman, P. H. M., & van Zeeland, A. A. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.1277 · Cited by 171 · see citing works
Mechanisms of ultraviolet-induced mutation
Schaaper, R. M., Dunn, R. L., & Glickman, B. W. (1987) · Journal of Molecular Biology · doi:10.1016/0022-2836(87)90305-6 · Cited by 132 · see citing works
Chen, R., Maher, V. M., & McCormick, J. J. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.21.8680 · Cited by 125 · see citing works
Amplification and purification of UvrA, UvrB, and UvrC proteins of Escherichia coli.
Thomas, D. C., Levy, M. S., & Sancar, A. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39318-3 · Cited by 122 · see citing works
Self-citationSelby, C. P., & Sancar, A. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.18.8232 · Cited by 113 · see citing works
Self-citationLeadon, S. A., & Lawrence, D. A. (1991) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(91)90019-l · Cited by 108 · see citing works
Organization and structure of an E. coli tRNA operon containing seven tRNA genes
Nakajima, N., Ozeki, H., & Shimura, Y. (1981) · Cell · doi:10.1016/0092-8674(81)90288-9 · Cited by 85 · see citing works
Differential repair of premutational UV-lesions at tRNA genes in E. coli
Bockrath, R. C., & Palmer, J. E. (1977) · Molecular and General Genetics MGG · doi:10.1007/bf00283485 · Cited by 83 · see citing works
Site and strand specificity of UVB mutagenesis in the SUP4-o gene of yeast.
Armstrong, J. D., & Kunz, B. A. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.22.9005 · Cited by 80 · see citing works
Mutation and the Repair of Radiation Damage in Bacteria
Witkin, E. M. (1966) · Radiation Research Supplement · doi:10.2307/3583550 · Cited by 75 · see citing works
Self-citationOsborn, M., & Person, S. (1967) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(67)90013-9 · Cited by 69 · see citing works
Bridges, B. A., & Mottershead, R. (1971) · Mutation Research · doi:10.1016/0027-5107(71)90120-5 · Cited by 67 · see citing works
Vos, J. H., & Wauthier, E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.4.2245 · Cited by 66 · see citing works
Nishioka, H., & Doudney, C. O. (1970) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(70)90017-5 · Cited by 64 · see citing works
Doudney, C. O., & Haas, F. L. (1960) · Genetics · doi:10.1093/genetics/45.11.1481 · Cited by 50 · see citing works
Slow excision repair in an mfd mutant of Escherichia coli B/r
George, D., & Witkin, E. (2004) · Molecular and General Genetics MGG · doi:10.1007/bf00332704 · Cited by 42 · see citing works
Self-citationDNA Strand Specificity for UV-Induced Mutations in Mammalian Cells
Vrieling, H., Rooijen, M. L. V., Groen, N. A., et al. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.3.1277-1283.1989 · Cited by 42 · see citing works
Koehler, D. R., Awadallah, S. S., & Glickman, B. W. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99023-x · Cited by 34 · see citing works
George, D. L., & Witkin, E. M. (1975) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(75)90229-8 · Cited by 34 · see citing works
Self-citationConcepts and models for DNA repair: FromEscherichia coli to mammalian cells
Hanawalt, P. C. (1989) · Environmental and Molecular Mutagenesis · doi:10.1002/em.2850140617 · Cited by 30 · see citing works
Mutation frequency decline in Escherichia coli B/r after mutagenesis with ethyl methanesulfonate
Bockrath, R. C., Barlow, A., & Engstrom, J. (1987) · Mutation Research/DNA Repair Reports · doi:10.1016/0167-8817(87)90006-x · Cited by 29 · see citing works
Engstrom, J., Larsen, S. H., Rogers, S., & Bockrath, R. C. (1984) · Mutation Research/DNA Repair Reports · doi:10.1016/0167-8817(84)90032-4 · Cited by 27 · see citing works
The role of nutrient broth supplementation in UV mutagenesis of E. coli
Bockrath, R. C., & Cheung, M. K. (1973) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(73)90109-7 · Cited by 22 · see citing works
Carothers, A. M., Urlaub, G., Mucha, J., Harvey, R. G., Chasin, L. A., & Grünberger, D. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5464 · Cited by 17 · see citing works
Vos, J. H., & Wauthier, E. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.4.2245-2252.1991 · Cited by 12 · see citing works
Garvey, N., Witkin, E. M., & Brash, D. E. (1989) · Molecular and General Genetics MGG · doi:10.1007/bf00259607 · Cited by 10 · see citing works
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Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
Sancar, A., Lindsey-Boltz, L. A., Ünsal-Kaçmaz, K., & Linn, S. (2004) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.73.011303.073723 · Cited by 3,317 · see citing works
Self-citationWu, M., Sun, L. V., Vamathevan, J., Riegler, M., Deboy, R., Brownlie, J. C., McGraw, E. A., Martin, W., Esser, C., Ahmadinejad, N., et al. (2004) · PLoS Biology · doi:10.1371/journal.pbio.0020069 · Cited by 851 · see citing works
“The only noteworthy DNA repair gene absent from w Mel and present in the more slowly evolving Rickettsia is mfd, which is involved in targeting DNA repair to the transcribed strand of actively transcribing genes in other species (Selby et al. 1991).”
Troelstra, C., van Gool, A., de Wit, J., Vermeulen, W., Bootsma, D., & Hoeijmakers, J. H. J. (1992) · Cell · doi:10.1016/0092-8674(92)90390-x · Cited by 729 · see citing works
Evolution of the SNF2 family of proteins: subfamilies with distinct sequences and functions
Eisen, J. A., Sweder, K., & Hanawalt, P. C. (1995) · Nucleic Acids Research · doi:10.1093/nar/23.14.2715 · Cited by 712 · see citing works
Molecular Mechanism of Transcription-Repair Coupling
Selby, C. P., & Sancar, A. (1993) · Science · doi:10.1126/science.8465200 · Cited by 656 · see citing works
Self-citationFousteri, M., & Mullenders, L. H. (2008) · Cell Research · doi:10.1038/cr.2008.6 · Cited by 487 · see citing works
Functions of the gene products of Escherichia coli
Riley, M. A. (1993) · Microbiological Reviews · doi:10.1128/mr.57.4.862-952.1993 · Cited by 367 · see citing works
Reardon, J. T., & Sancar, A. (2005) · Progress in Nucleic Acid Research and Molecular Biology · doi:10.1016/s0079-6603(04)79004-2 · Cited by 350 · see citing works
Self-citationDNA REPAIR GENES AND PROTEINS OF SACCHAROMYCES CEREVISIAE
Prakash, S., Sung, P., & Prakash, L. (1993) · Annual Review of Genetics · doi:10.1146/annurev.ge.27.120193.000341 · Cited by 303 · see citing works
Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells
van Hoffen, A., Natarajan, A. T., Mayne, L. V., van Zeeland, A. A., Mullenders, L. H. F., & Venema, J. (1993) · Nucleic Acids Research · doi:10.1093/nar/21.25.5890 · Cited by 291 · see citing works
Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes
Mellon, I., Rajpal, D. K., Koi, M., Boland, C. R., & Champe, G. N. (1996) · Science · doi:10.1126/science.272.5261.557 · Cited by 284 · see citing works
Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture)
Sancar, A. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201601524 · Cited by 273 · see citing works
Self-citationAflatoxin B1-induced DNA damage and its repair
Bedard, L. L., & Massey, T. E. (2006) · Cancer Letters · doi:10.1016/j.canlet.2005.11.018 · Cited by 264 · see citing works
ADAPTIVE MUTATION: The Uses of Adversity
Foster, P. L. (1993) · Annual Review of Microbiology · doi:10.1146/annurev.mi.47.100193.002343 · Cited by 262 · see citing works
Sancar, A., & Tang, M. (1993) · Photochemistry and Photobiology · doi:10.1111/j.1751-1097.1993.tb09233.x · Cited by 256 · see citing works
Self-citationRAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.
van Gool, A. J., Verhage, R., Swagemakers, S. M., van de Putte, P., Brouwer, J., Troelstra, C., Bootsma, D., & Hoeijmakers, J. H. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06871.x · Cited by 246 · see citing works
Effect of DNA lesions on transcription elongation
Tornaletti, S., & Hanawalt, P. C. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80046-7 · Cited by 235 · see citing works
Linkage Map ofEscherichia coliK-12, Edition 10: The Traditional Map
Berlyn, M. K. B. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.3.814-984.1998 · Cited by 216 · see citing works
Leadon, S. A., & Cooper, P. K. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.22.10499 · Cited by 215 · see citing works
Structural Basis for Bacterial Transcription-Coupled DNA Repair
Deaconescu, A. M., Chambers, A. L., Smith, A. J., Nickels, B. E., Hochschild, A., Savery, N. J., & Darst, S. A. (2006) · Cell · doi:10.1016/j.cell.2005.11.045 · Cited by 197 · see citing works
Verhage, R. A., Zeeman, A., de Groot, N., Gleig, F., Bang, D. D., van de Putte, P., & Brouwer, J. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.6135 · Cited by 199 · see citing works
RNA polymerase II stalled at a thymine dimer: footprint and effect on excision repair
Selby, C. P., Drapkin, R., Reinberg, D., & Sancar, A. (1997) · Nucleic Acids Research · doi:10.1093/nar/25.4.787 · Cited by 186 · see citing works
Self-citationSaxowsky, T. T., & Doetsch, P. W. (2006) · Chemical Reviews · doi:10.1021/cr040466q · Cited by 176 · see citing works
Sweder, K., & Hanawalt, P. C. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.10696 · Cited by 175 · see citing works
Mellon, I., & Champe, G. N. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.3.1292 · Cited by 173 · see citing works
Structure and Function of Transcription-Repair Coupling Factor
Selby, C. P., & Sancar, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4882 · Cited by 157 · see citing works
Self-citationThe Regulatory Networks That Control Clostridium difficile Toxin Synthesis
Martin‐Verstraete, I., Johann, P., & Dupuy, B. (2016) · Toxins · doi:10.3390/toxins8050153 · Cited by 149 · see citing works
Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases.
Zhou, W., & Doetsch, P. W. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.14.6601 · Cited by 145 · see citing works
Mechanisms of transcription-repair coupling and mutation frequency decline
Selby, C. P., & Sancar, A. (1994) · Microbiological Reviews · doi:10.1128/mr.58.3.317-329.1994 · Cited by 139 · see citing works
Self-citationDNA Repair Rates Mapped Along the Human PGK1 Gene at Nucleotide Resolution
Gao, S., Drouin, R., & Holmquist, G. P. (1994) · Science · doi:10.1126/science.8128226 · Cited by 135 · see citing works
Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells.
Sage, É., Lamolet, B., Brulay, E., Moustacchi, E., Chteauneuf, A., & Drobetsky, E. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.1.176 · Cited by 121 · see citing works
Replication of Damaged DNA and the Molecular Mechanism of Ultraviolet Light Mutagenesis
Livneh, Z., Cohen‐Fix, O., Skaliter, R., & Paz-Elizur, T. (1993) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409239309085136 · Cited by 120 · see citing works
Structure and Function of Transcription-Repair Coupling Factor
Selby, C. P., & Sancar, A. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.9.4890 · Cited by 118 · see citing works
Self-citationDNA repair in differentiated cells: Some new answers to old questions
Nouspikel, T. P. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.07.006 · Cited by 107 · see citing works
Model for XPC-independent Transcription-coupled Repair of Pyrimidine Dimers in Humans
Mu, D., & Sancar, A. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.12.7570 · Cited by 106 · see citing works
Self-citationMolecular cloning of RAD16, a gene involved in differential repair inSaccharomyces cerevisiae
Bang, D. D., Verhage, R. A., Goosen, N., Brouwer, J., & van de Putte, P. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.15.3925 · Cited by 106 · see citing works
Morita, R., Nakane, S., Shimada, A., Inoue, M., Iino, H., Wakamatsu, T., Fukui, K., Nakagawa, N., Masui, R., & Kuramitsu, S. (2010) · Journal of Nucleic Acids · doi:10.4061/2010/179594 · Cited by 107 · see citing works
Hanawalt, P. C., & Mellon, I. (1993) · Current Biology · doi:10.1016/0960-9822(93)90156-i · Cited by 102 · see citing works
Nucleotide Excision Repair in E. Coli and Man
Sancar, A., & Reardon, J. T. (2004) · Advances in protein chemistry · doi:10.1016/s0065-3233(04)69002-4 · Cited by 99 · see citing works
Self-citationCockayne syndrome – a primary defect in DNA repair, transcription, both or neither?
Friedberg, E. C. (1996) · BioEssays · doi:10.1002/bies.950180908 · Cited by 100 · see citing works
Mfd, the bacterial transcription repair coupling factor: translocation, repair and termination
Roberts, J., & Park, J. (2004) · Current Opinion in Microbiology · doi:10.1016/j.mib.2004.02.014 · Cited by 99 · see citing works
Verhage, R. A., Van Gool, A. J., Groot, N. D., Hoeijmakers, J. H. J., Putte, P. V. D., & Brouwer, J. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.2.496 · Cited by 98 · see citing works
Crowley, D. J., & Hanawalt, P. C. (1998) · Journal of Bacteriology · doi:10.1128/jb.180.13.3345-3352.1998 · Cited by 96 · see citing works
Cohen, S., Lewis, C. A., Mooney, R. A., Kohanski, M. A., Collins, J. J., Landick, R. C., & Walker, G. C. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005203107 · Cited by 94 · see citing works
Mechanism of action of the Escherichia coli UvrABC nuclease: Clues to the damage recognition problem
Houten, B. V., & Snowden, A. (1993) · BioEssays · doi:10.1002/bies.950150108 · Cited by 94 · see citing works
(A)BC excinuclease: the Escherichia coli nucleotide excision repair enzyme
Lin, J., & Sancar, A. (1992) · Molecular Microbiology · doi:10.1111/j.1365-2958.1992.tb01398.x · Cited by 94 · see citing works
Self-citationGenetic analysis of twenty-two patients with Cockayne syndrome
Stefanini, M., Fawcett, H., Botta, E., Nardò, T., & Lehmann, A. R. (1996) · Human Genetics · doi:10.1007/bf02267059 · Cited by 89 · see citing works
Lack of transcription-coupled repair in mammalian ribosomal RNA genes
Christians, F. C., & Hanawalt, P. C. (1993) · Biochemistry · doi:10.1021/bi00090a030 · Cited by 89 · see citing works
Oller, A. R., Fijałkowska, I. J., Dunn, R. L., & Schaaper, R. M. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.11036 · Cited by 84 · see citing works
Molecular mechanisms and genomic maps of DNA excision repair in Escherichia coli and humans
Hu, J., Selby, C. P., Adar, S., Adebali, O., & Sancar, A. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.r117.807453 · Cited by 81 · see citing works
Self-citationAvoiding and resolving conflicts between DNA replication and transcription
Rudolph, C. J., Dhillon, P., Moore, T., & LLOYD, R. (2007) · DNA repair · doi:10.1016/j.dnarep.2007.02.017 · Cited by 78 · see citing works
Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase
Adebalı, O., Chiou, Y., Hu, J., Sancar, A., & Selby, C. P. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1700230114 · Cited by 78 · see citing works
Self-citationTherefore, what are recombination proteins there for?
Courcelle, J., Ganesan, A. K., & Hanawalt, P. C. (2001) · BioEssays · doi:10.1002/bies.1065 · Cited by 76 · see citing works
Novel Role of mfd : Effects on Stationary-Phase Mutagenesis in Bacillus subtilis
Ross, C. A., Pybus, C. A., Pedraza‐Reyes, M., Sung, H., Yasbin, R. E., & Robleto, E. A. (2006) · Journal of Bacteriology · doi:10.1128/jb.00980-06 · Cited by 75 · see citing works
Hanawalt, P. C. (1995) · Mutation Research/DNA Repair · doi:10.1016/0921-8777(94)00061-a · Cited by 73 · see citing works
Kunala, S., & Brash, D. E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.22.11031 · Cited by 70 · see citing works
Molecular Mechanisms of Transcription-Coupled Repair
Selby, C. P., Lindsey‐Boltz, L. A., Li, W., & Sancar, A. (2023) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-041522-034232 · Cited by 67 · see citing works
Self-citationDr. NO and Mr. Toxic – the versatile role of nitric oxide
Porrini, C., Ramarao, N., & Tran, S. (2019) · Biological Chemistry · doi:10.1515/hsz-2019-0368 · Cited by 70 · see citing works
Transcription-repair coupling and mutation frequency decline
Selby, C. P., & Sancar, A. (1993) · Journal of Bacteriology · doi:10.1128/jb.175.23.7509-7514.1993 · Cited by 68 · see citing works
Self-citationStructural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction
Westblade, L. F., Campbell, E. A., Pukhrambam, C., Padovan, J. C., Nickels, B. E., Lamour, V., & Darst, S. A. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq692 · Cited by 67 · see citing works
Transcription-coupled repair: An update
Spivak, G. (2016) · Archives of Toxicology · doi:10.1007/s00204-016-1820-x · Cited by 65 · see citing works
Tijsterman, M., Verhage, R. A., van de Putte, P., Jong, J. G. T.-D., & Brouwer, J. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.15.8027 · Cited by 63 · see citing works
Richardson, M. (1999) · doi:10.1002/(sici)1521-1878(199907)21:7
Mfd Protein and Transcription–Repair Coupling in Escherichia coli
Selby, C. P. (2016) · Photochemistry and Photobiology · doi:10.1111/php.12675 · Cited by 62 · see citing works
Self-citationTranscription factor IIH: A key player in the cellular response to DNA damage
Frit, P., Bergmann, E., & Egly, J. (1999) · Biochimie · doi:10.1016/s0300-9084(99)80035-2 · Cited by 59 · see citing works
Formation and Recognition of UV-Induced DNA Damage within Genome Complexity
Berens, P. J. T., & Molinier, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186689 · Cited by 59 · see citing works
Defects in the Flagellar Motor Increase Synthesis of Poly-γ-Glutamate in Bacillus subtilis
Chan, J. M., Guttenplan, S. B., & Kearns, D. B. (2013) · Journal of Bacteriology · doi:10.1128/jb.01217-13 · Cited by 57 · see citing works
Verhage, R. A., Zeeman, A., de Groot, N., Gleig, F., Bang, D. D., van de Putte, P., & Brouwer, J. (1994) · Molecular and Cellular Biology · doi:10.1128/mcb.14.9.6135-6142.1994 · Cited by 56 · see citing works
Mammalian nucleotide excision repair
Ma, L., Hoeijmakers, J. H. J., & van der Eb, A. J. (1995) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/0304-419x(95)00008-4 · Cited by 56 · see citing works
Robleto, E. A., Yasbin, R. E., Ross, C. A., & Pedraza‐Reyes, M. (2007) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230701597717 · Cited by 55 · see citing works
Transcription-Coupled DNA Repair in Prokaryotes
Ganesan, A. K., Spivak, G., & Hanawalt, P. C. (2012) · Progress in molecular biology and translational science · doi:10.1016/b978-0-12-387665-2.00002-x · Cited by 52 · see citing works
A Structural Model for the Damage-sensing Complex in Bacterial Nucleotide Excision Repair
Pakotiprapha, D., Liu, Y., Verdine, G. L., & Jeruzalmi, D. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m900571200 · Cited by 51 · see citing works
The complex choreography of transcription-coupled repair
Spivak, G., & Ganesan, A. K. (2014) · DNA Repair · doi:10.1016/j.dnarep.2014.03.025 · Cited by 51 · see citing works
Transcription-Coupled DNA Repair
Sweder, K., & Hanawalt, P. C. (1993) · Science · doi:10.1126/science.8211165 · Cited by 48 · see citing works
RNA Polymerase Bypass at Sites of Dihydrouracil: Implications for Transcriptional Mutagenesis
Liu, J., Zhou, W., & Doetsch, P. W. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.12.6729 · Cited by 47 · see citing works
Structural basis for transcription complex disruption by the Mfd translocase
Kang, J. Y., Llewellyn, E., Chen, J., Olinares, P. D. B., Brewer, J. J., Chait, B. T., Campbell, E. A., & Darst, S. A. (2021) · eLife · doi:10.7554/elife.62117 · Cited by 46 · see citing works
Roots: Mutation frequency decline revisited
Witkin, E. M. (1994) · BioEssays · doi:10.1002/bies.950160613 · Cited by 46 · see citing works
Self-citationMechanisms of Genome Maintenance in Plants: Playing It Safe With Breaks and Bumps
Raina, A., Sahu, P. K., Laskar, R. A., Rajora, N., Sao, R., Khan, S., & Ganai, R. A. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.675686 · Cited by 44 · see citing works
Duan, M., Selvam, K., Wyrick, J. J., & Mao, P. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2003868117 · Cited by 45 · see citing works
Mfd translocase is necessary and sufficient for transcription-coupled repair in Escherichia coli
Adebalı, O., Sancar, A., & Selby, C. P. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.c117.818807 · Cited by 44 · see citing works
Self-citationSweder, K., Verhage, R. A., Crowley, D. J., Crouse, G. F., Brouwer, J., & Hanawalt, P. C. (1996) · Genetics · doi:10.1093/genetics/143.3.1127 · Cited by 44 · see citing works
Rethinking transcription coupled DNA repair
Kamarthapu, V., & Nudler, E. (2015) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.12.005 · Cited by 42 · see citing works
Deaconescu, A. M., Sevostyanova, A., Artsimovitch, I., & Grigorieff, N. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115105109 · Cited by 43 · see citing works
Factor-dependent archaeal transcription termination
Walker, J. E., Luyties, O., & Santangelo, T. J. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704028114 · Cited by 42 · see citing works
Niche-specificity factors of a marine oil-degrading bacteriumAlcanivorax borkumensisSK2
Sabirova, J. S., Chernikova, T. N., Timmis, K. N., & Golyshin, P. N. (2008) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2008.01222.x · Cited by 39 · see citing works
Morita, R., Nakagawa, N., Kuramitsu, S., & Masui, R. (2008) · The Journal of Biochemistry · doi:10.1093/jb/mvn065 · Cited by 39 · see citing works
Liu, J., & Doetsch, P. W. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.7.1707 · Cited by 39 · see citing works
Baharoglu, Z., Babosan, A., & Mazel, D. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1259 · Cited by 38 · see citing works
Dorazi, R., Götz, D., Munro, S., Bernander, R., & White, M. F. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05516.x · Cited by 37 · see citing works
Ghodke, H. B., Ho, H. N., & van Oijen, A. M. (2020) · Nature Communications · doi:10.1038/s41467-020-15179-y · Cited by 36 · see citing works
Chakraborty, A., Tapryal, N., Islam, A., MITRA, S. P., & Hazra, T. K. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103204 · Cited by 36 · see citing works
Pruteanu, M., & Baker, T. A. (2008) · Molecular Microbiology · doi:10.1111/j.1365-2958.2008.06574.x · Cited by 33 · see citing works
Schalow, B. J., Courcelle, C. T., & Courcelle, J. (2012) · Journal of Bacteriology · doi:10.1128/jb.06725-11 · Cited by 36 · see citing works
The bacterial transcription repair coupling factor
Deaconescu, A. M., Savery, N. J., & Darst, S. A. (2007) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2007.01.005 · Cited by 36 · see citing works
Islas, Á. L., Baker, F. J., & Hanawalt, P. C. (1994) · Biochemistry · doi:10.1021/bi00201a029 · Cited by 36 · see citing works
Role of DNA Excision Repair Gene Defects in the Etiology of Cancer
Ford, J. M., & Hanawalt, P. C. (1997) · Current topics in microbiology and immunology · doi:10.1007/978-3-642-60505-5_5 · Cited by 35 · see citing works
A Peek Inside the Machines of Bacterial Nucleotide Excision Repair
Kraithong, T., Hartley, S., Jeruzalmi, D., & Pakotiprapha, D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22020952 · Cited by 32 · see citing works
Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM
Olinares, P. D. B., Kang, J. Y., Llewellyn, E., Chiu, C., Chen, J., Malone, B., Saecker, R. M., Campbell, E. A., Darst, S. A., & Chait, B. T. (2020) · Structure · doi:10.1016/j.str.2020.11.001 · Cited by 32 · see citing works
Pervasive Transcription-coupled DNA repair in E. coli
Martinez, B., Bharati, B. K., Epshtein, V., & Nudler, E. (2022) · Nature Communications · doi:10.1038/s41467-022-28871-y · Cited by 32 · see citing works
Friedberg, E. C., Bardwell, A. J., Bardwell, L., Wang, Z., & Dianov, G. L. (1994) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(94)90272-0 · Cited by 32 · see citing works
- Authors
- Selby, C. P., Witkin, E. M., & Sancar, A.
- Affiliations
- Rutgers, The State University of New Jersey (US)
- University of North Carolina at Chapel Hill (US)
- ORCID
- Venue
- Proceedings of the National Academy of Sciences
- Publisher
- National Academy of Sciences
- Published
- 1991-12-15
- Volume
- 88
- Issue
- 24
- Pages
- 11574-11578
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- PMC
- PMC53178
- OpenAlex
- W2153139649
- Cited by
- 215
- References
- 37
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 2 · 2023: 7 · 2022: 4 · 2021: 10 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 5 · 2016: 8 · 2015: 3 · 2014: 6 · 2013: 7 · 2012: 4
- FWCI
- 6.09
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Proceedings of the National Academy of Sciences (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of General Medical Sciences (R01GM032833, GM32833)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA Repair Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Bacterial Genetics and Biotechnology
- Health Sciences › Medicine › Pathology and Forensic Medicine › Genetic factors in colorectal cancer
- Keywords
- strand-specific repair, excision repair, DNA repair, Escherichia coli
- MeSH terms
- Alleles, Bacterial Proteins, Cell-Free System, DNA Repair, Escherichia coli, Genes, Bacterial, Genetic Complementation Test, Mutation, Phenotype, Plasmids, SOS Response, Genetics, Transcription Factors, Transcription, Genetic, Ultraviolet Rays, Genes, Suppressor, Mutagenesis
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