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Cited by 279Cardiac electrophysiology and arrhythmiasIon channel regulation and functionCardiac Arrhythmias and Treatments

Analysis of the effects of changes in rate and rhythm upon electrical activity in the heart

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Boyet, M.R., Jewell, B.R.·1981·Progress in Biophysics and Molecular Biology
DOI 10.1016/0079-6107(81)90003-1
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  • As pacing frequency increased, APD50 and conduction velocity decreased in hvCOC, indicating rate-adaptation.

    “As the pacing frequency was increased (Fig. 5c) (i.e., shorter basic cycle length, BCL), the AP duration at 50% amplitude (APD50) (Fig. 5d) and the conduction velocity (CV) (Fig. 5e) decreased, indicating the ability of hvCOC to rate-adapt, another key physiological feature of native cardiac cells and tissues [40,41].”

    From Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells (2018) · cites this paper as [41]

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2 of the 201 references couldn’t be matched to a known paper.

Research works printed but not linked: 9

  1. ALLEN, D. G. (1975) The variations in contractility of cardiac muscle. Ph.D. thesis, University of London.
  2. ALT~IAN, P. L. and DITTOS, D. S. (1974) Biolooy Data Book, Vol. 3, Federation of American Societies for Experimental Biology. Bethesda, Maryland.
  3. BOVETT, M. R. (1977) Factors influencing the duration of the cardiac action potential. Ph.D. thesis, University of London.
  4. COLATSKY, T. J. (1977) The effects of rate and calcium on repolarisation in dog Purkinje fibers. Ph.D. thesis, State University of New York at Buffalo.
  5. Hno, oKA, M. and SANO, T. (1977) Mechanism for prolonged action potentials in premature excitations of ventricular muscle fibres. Proc. Int. Un. Physiol. Sci. 13, 324.
  6. HOF~t~, B. F. and Cs.~e~w.a.D, P. F. (1960) Eiectrophysiol~y of th~ Hmrt. McGraw-Hit, New York.
  7. K~rovcm, S. and Y^M~ZAKI, R. (1970) Proc. Jap. Acad. 46, 387-392.
  8. NIEDE~GEgr,~, R., O~D~N, D. C. and PAGe, S. (1976) Contractile activation and calcium movements in heart cells. In Calcium in Biolooical Systems, Symposium of the Society for Experimental Biology. University Press, Cambridge.
  9. SPECTOR, W. S. (1956) Handbook of Bioloyy Data. W. B. Saunders & Co., Philadelphia and London.

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Authors
Boyet, M. R., & Jewell, B. R.
Affiliations
University of Leeds (GB)
Venue
Progress in Biophysics and Molecular Biology
Publisher
Elsevier BV
Published
1981
Volume
36
Issue
1
Pages
1-52
ISSN
0079-6107 (ISSN-L)
DOI
10.1016/0079-6107(81)90003-1
OpenAlex
W1985547906
Cited by
279
References
201
Citations by year
2026: 1 · 2024: 2 · 2023: 2 · 2022: 4 · 2021: 1 · 2020: 3 · 2019: 3 · 2018: 3 · 2017: 2 · 2016: 2 · 2015: 1 · 2013: 1 · 2012: 4
FWCI
13.33
Type
journal article
Language
en
Open access
Licence
Locations
  • Progress in Biophysics and Molecular Biology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Ion channel regulation and function
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords
heart rate, cardiac rhythm, cardiac electrical activity, sodium current, atrial muscle, Purkinje fibers, ventricular myocardium, temperature effects, cardiac electrophysiology
MeSH terms
Action Potentials, Animals, Calcium, Heart Atria, Heart Conduction System, Heart Rate, Heart Ventricles, Membrane Potentials, Potassium, Purkinje Fibers, Sodium

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