On the origin of RNA splicing and introns

Sharp, Phillip A.·1985·Cell

DOI 10.1016/0092-8674(85)90092-3

Open this paper in CoChat — free account

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/0092-8674(85)90092-3

Cites

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Origin of life: The RNA world
Gilbert, W. (1986) · Nature · doi:10.1038/319618a0 · Cited by 2,721
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
Licatalosi, D. D., Mele, A., Fak, J. J., Ule, J., Kayikci, M., Chi, S. W., Clark, T. A., Schweitzer, A. C., Blume, J. E., Wang, X., et al. (2008) · Nature · doi:10.1038/nature07488 · Cited by 1,352
RNA-catalyzed RNA polymerization: Accurate and general RNA-templated primer extension.
Johnston, W. K., Unrau, P. J., Lawrence, M. S., Glasner, M. E., & Bartel, D. P. (2001) · Science · doi:10.1126/science.1060786 · Cited by 768
RNA evolution and the origins of life
Joyce, G. F. (1989) · Nature · doi:10.1038/338217a0 · Cited by 658
Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene.
Higashi, Y., Yoshioka, H., Yamane, M., Gotoh, O., & Fujii-Kuriyama, Y. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.9.2841 · Cited by 555
The origins of the RNA world
Robertson, M. P., & Joyce, G. F. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003608 · Cited by 556
Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs
Kambach, C., Walke, S., Young, R., Avis, J. M., de la Fortelle, E., Raker, V. A., Lührmann, R., Li, J., & Nagai, K. (1999) · Cell · doi:10.1016/s0092-8674(00)80550-4 · Cited by 387
Rates of decomposition of ribose and other sugars - implications for chemical evolution
Larralde, R., Robertson, M. P., & Miller, S. L. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.18.8158 · Cited by 344
Prebiotic Ribose Synthesis: A Critical Analysis
Shapiro, R. (1988) · Origins of life and evolution of the biosphere · doi:10.1007/bf01808782 · Cited by 276
The Path from the RNA World
Poole, A. M., Jeffares, D. C., & Penny, D. (1998) · Journal of Molecular Evolution · doi:10.1007/pl00006275 · Cited by 274
RNA-catalysed RNA polymerization using nucleoside triphosphates
Ekland, E. H., & Bartel, D. P. (1996) · Nature · doi:10.1038/382373a0 · Cited by 250
Circular RNAs: relics of precellular evolution?
Diener, T. O. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.23.9370 · Cited by 201
A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis
Doudna, J. A., Couture, S., & Szostak, J. W. (1991) · Science · doi:10.1126/science.1707185 · Cited by 117
Multilevel Selection in Models of Prebiotic Evolution II: A Direct Comparison of Compartmentalization and Spatial Self-Organization
Takeuchi, N., & Hogeweg, P. (2009) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1000542 · Cited by 104
Comparative Analysis of Teleost Genome Sequences Reveals an Ancient Intron Size Expansion in the Zebrafish Lineage
Moss, S. P., Joyce, D. A., Humphries, S., Tindall, K. J., & Lunt, D. H. (2011) · Genome Biology and Evolution · doi:10.1093/gbe/evr090 · Cited by 28
MISF2 Encodes an Essential Mitochondrial Splicing Cofactor Required for nad2 mRNA Processing and Embryo Development in Arabidopsis thaliana
Nguyen, T.-T., Best, C., Shevtsov, S., Zmudjak, M., Quadrado, M., Mizrahi, R., Zer, H., Mireau, H., & Ostersetzer-Biran, O. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052670 · Cited by 11

Authors: Sharp, P. A.
Venue: Cell
Publisher: Elsevier BV
Published: 1985-09
Volume: 42
Issue: 2
Pages: 397-400
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/0092-8674(85)90092-3
OpenAlex: W2006628267
Cited by: 485
References: 0
FWCI: 11.82
Type: journal article
Language: en
Open access: closed

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review