The p53 proto-oncogene can act as a suppressor of transformation

A new technique for the assay of infectivity of human adenovirus 5 DNA

Graham, F. L., & van der Eb, A. J. (1973) · Virology · doi:10.1016/0042-6822(73)90341-3 · Cited by 9,302

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

Friend, S. H., Bernards, R., Rogelj, S., Weinberg, R. A., Rapaport, J. M., Albert, D. M., & Dryja, T. P. (1986) · Nature · doi:10.1038/323643a0 · Cited by 2,948

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Land, H., Parada, L. F., & Weinberg, R. A. (1983) · Nature · doi:10.1038/304596a0 · Cited by 2,804

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

Southern, P. J., & Berg, P. R. (1982) · PubMed · Cited by 2,740

T antigen is bound to a host protein in SY40-transformed cells

Lane, D. P., & Crawford, L. V. (1979) · Nature · doi:10.1038/278261a0 · Cited by 2,456

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

Linzer, D. I. H., & Levine, A. J. (1979) · Cell · doi:10.1016/0092-8674(79)90293-9 · Cited by 1,814

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

DeCaprio, J. A., Ludlow, J. W., Figge, J., Shew, J.-Y., Huang, C.-M., Lee, W.-H., Marsilio, E., Paucha, E., & Livingston, D. M. (1988) · Cell · doi:10.1016/0092-8674(88)90559-4 · Cited by 1,459

Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence

Lee, W., Bookstein, R., Hong, F., Young, L.-J., Shew, J., & Lee, E. Y.-H. P. (1987) · Science · doi:10.1126/science.3823889 · Cited by 1,417

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

Whyte, P., Buchkovich, K. J., Horowitz, J. M., Friend, S. H., Raybuck, M., Weinberg, R. A., & Harlow, E. (1988) · Nature · doi:10.1038/334124a0 · Cited by 1,403

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

Ruley, H. E. (1983) · Nature · doi:10.1038/304602a0 · Cited by 1,248

Immortalization of primary cells by DNA tumor viruses

Linder, S., & Marshall, H. M. (1990) · Experimental Cell Research · doi:10.1016/0014-4827(90)90027-8 · Cited by 44

Expression of the novel tumour suppressor p33ING1 is independent of p53

Cheung, K. J., Bush, J., Jia, W. W.-G., & Li, G. (2000) · British Journal of Cancer · doi:10.1054/bjoc.2000.1464 · Cited by 44

Low prevalence of expression of p53 oncoprotein in oral carcinomas from Sri Lanka associated with betel and tobacco chewing

Ranasinghe, A. W., Warnakulasuriya, S., & Johnson, N. W. (1993) · European Journal of Cancer Part B Oral Oncology · doi:10.1016/0964-1955(93)90038-g · Cited by 44

Evidence for and possible mechanisms of non-genotoxic carcinogenesis in the rodent thyroid

Thomas, G. A., & Williams, E. D. (1991) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(91)90068-y · Cited by 44

Simian virus 40 large T antigen and p53 are microtubule-associated proteins in transformed cells.

Maxwell, S. A., Ames, S. K., Sawai, E. T., Decker, G. L., Cook, R. G., & Butel, J. S. (1991) · PubMed · Cited by 44

p53 and Human Malignancies

Rotter, V., & Prokocimer, M. (1991) · Advances in cancer research · doi:10.1016/s0065-230x(08)61001-5 · Cited by 44

Alterations of the p53 gene in Epstein-Barr virus-associated immunodeficiency-related lymphomas

Edwards, R. H., & Raab‐Traub, N. (1994) · Journal of Virology · doi:10.1128/jvi.68.3.1309-1315.1994 · Cited by 44

Expression of the p53 protein in a spectrum of astrocytic tumours

Ellison, D. W., Gatter, K. C., Steart, P. V., Lane, D. P., & Weller, R. O. (1992) · The Journal of Pathology · doi:10.1002/path.1711680408 · Cited by 44

Cystatin C as a p53‐inducible apoptotic mediator that regulates cathepsin L activity

Mori, J., Tanikawa, C., Funauchi, Y., Lo, P. H. Y., Nakamura, Y., & Matsuda, K. (2016) · Cancer Science · doi:10.1111/cas.12881 · Cited by 45

Molecular Epidemiology of Human Cancer

Hussain, S. P., & Harris, C. C. (1998) · Recent results in cancer research/Recent Results in Cancer Research · doi:10.1007/978-3-642-46870-4_2 · Cited by 44

Prognostic Factors in Papillary and Follicular Thyroid Carcinomas

Godballe, C., Asschenfeldt, P., Jørgensen, K. E., Bastholt, L., CLAUSEN, P. P., Hansen, T. P., Hansen, O., & Bentzen, S. M. (1998) · The Laryngoscope · doi:10.1097/00005537-199802000-00016 · Cited by 43

Diet, Helicobacter pylori, and p53 mutations in gastric cancer: a molecular epidemiology study in Italy.

Palli, D., Caporaso, N. E., Shiao, Y., Saieva, C., Amorosi, A., Masala, G., Rice, J. M., & Fraumeni, J. F. (1997) · PubMed · Cited by 43

Flow cytometric measurement of p53 protein expression and DNA content in paraffin‐embedded tissue from bronchial carcinomas

Mørkve, O., & Lærum, O. D. (1991) · Cytometry · doi:10.1002/cyto.990120509 · Cited by 43

Immunohistological analysis of P53 expression in human skin tumors

Urano, Y., Oura, H., Sakaki, A., Nagae, H., Matsumoto, K., Fukuhara, K., Nagae, T., Arase, S., Ninomiya, Y., Nakanishi, H., et al. (1992) · Journal of Dermatological Science · doi:10.1016/0923-1811(92)90061-f · Cited by 43

p53 expression in lymphatic malignancies.

Soini, Y., Pääkkö, P. K., Alavaikko, M. J., & Vähäkangas, K. (1992) · Journal of Clinical Pathology · doi:10.1136/jcp.45.11.1011 · Cited by 43

No point mutation of ha‐ras or p53 genes expressed in preneoplastic‐to‐neoplastic progression as modeled in mouse JB6 cell variants

Sun, Y., Nakamura, K., Hegamyer, G. A., Dong, Z., & Colburn, N. H. (1993) · Molecular Carcinogenesis · doi:10.1002/mc.2940080111 · Cited by 43

Ironing out how p53 regulates ferroptosis

Murphy, M. E. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1615159113 · Cited by 42

Targeting P53 as a Future Strategy to Overcome Gemcitabine Resistance in Biliary Tract Cancers

Wu, C., Pan, Y., Yeh, C., & Lunec, J. (2020) · Biomolecules · doi:10.3390/biom10111474 · Cited by 44

The H19 gene is expressed within both epithelial and stromal components of human invasive adenocarcinomas

Dugimont, T., Curgy, J., Wernert, N., Delobelle, A., Raes, M., Joubel, A., Stéhelin, D., & Coll, J. (1995) · Biology of the Cell · doi:10.1016/0248-4900(96)85272-5 · Cited by 42

Hepatocellular proliferation and development of hepatocellular carcinoma: A case-control study in chronic hepatitis C

Dutta, U., Kench, J. G., Byth, K., Khan, M. H., Lin, R., Liddle, C., & Farrell, G. C. (1998) · Human Pathology · doi:10.1016/s0046-8177(98)90257-x · Cited by 42

Phosphorylation Studies on Rat p53 Using the Baculovirus Expression System

Fuchs, B., Hecker, D., & Scheidtmann, K. H. (1995) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1995.0625m.x · Cited by 42

The Significance of p53 Mutations as an Indicator of the Biological Behavior of Recurrent Hepatocellular Carcinomas

Sugo, H., Takamori, S., Kojima, K., Beppu, T., & Futagawa, S. (1999) · Surgery Today · doi:10.1007/bf02482774 · Cited by 42

Postatrophic hyperplasia of the prostate in Japan: Histologic and immunohistochemical features and p53 gene mutation analysis

Tsujimoto, Y., Takayama, H., Nonomura, N., Okuyama, Ä., & Aozasa, K. (2002) · The Prostate · doi:10.1002/pros.10116 · Cited by 42

Infrequent Involvement of P53 Mutations and Loss of Heterozygosity of 17p in the Tumorigenesis of Renal Cell Carcinoma

Uchida, Τ., Wada, C., Shitara, T., Egawa, S., Mashimo, S., & Koshiba, K. (1993) · The Journal of Urology · doi:10.1016/s0022-5347(17)35764-6 · Cited by 42

Mutations of the p53 tumour suppressor gene in haematologic neoplasms

Mori, N., Wada, M., Yokota, J., Terada, M., Okada, M., Teramura, M., Masuda, M., Hoshino, S., Motoji, T., Oshimi, K., et al. (1992) · British Journal of Haematology · doi:10.1111/j.1365-2141.1992.tb08213.x · Cited by 42

Photoprotective Effects of Dendrobium nobile Lindl. Polysaccharides against UVB-Induced Oxidative Stress and Apoptosis in HaCaT Cells

Long, Y., Wang, W., Zhang, Y., Du, F., Zhang, S., Li, Z., Deng, J., & Li, J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076120 · Cited by 42

Chilean pilot study on the risk of lung cancer associated with codon 72 polymorphism in the gene of protein p53

Irarrázabal, C. E. (2003) · Toxicology Letters · doi:10.1016/s0378-4274(02)00336-3 · Cited by 41

Downregulation of GFAP, TSP‐1, and p53 in human glioblastoma cell line, U373MG, by IE1 protein from human cytomegalovirus

Lee, K., Jeon, K., Kim, S., Kim, V. N., Choi, D. H., Kim, S. U., & Kim, S. (2005) · Glia · doi:10.1002/glia.20179 · Cited by 41

p53 and breast cancer

Ziyaie, D., Hupp, T. R., & Thompson, A. M. (2000) · The Breast · doi:10.1054/brst.2000.0199 · Cited by 41

Prognostic value of overexpression of p53 in human ovarian carcinoma patients receiving cisplatin

Nakayama, K., Takebayashi, Y., Nakayama, S., Hata, K., Fujiwaki, R., Fukumoto, M., & Miyazaki, K. (2003) · Cancer Letters · doi:10.1016/s0304-3835(02)00686-9 · Cited by 41

Expression of p53 protein has no independent prognostic value in breast cancer

Pietiläinen, T., Lipponen, P., Aaltomaa, S. H., Eskelinen, M. J., Kosma, V., & Syrjänen, K. J. (1995) · The Journal of Pathology · doi:10.1002/path.1711770303 · Cited by 41

Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology

Sirover, M. A. (1997) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(19970801)66:2 · Cited by 245

Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53

Scheidtmann, K. H., & Haber, A. (1990) · Journal of Virology · doi:10.1128/jvi.64.2.672-679.1990 · Cited by 41

The involvement of "tumor suppressor" p53 in normal and chronic myelogenous leukemia hemopoiesis.

Bi, S., Lanza, F., & Goldman, J. M. (1994) · PubMed · Cited by 41

p53 immunoreactivity in astrocytomas and its relationship to survival

Al‐Sarraj, S., & Bridges, L. (1995) · British Journal of Neurosurgery · doi:10.1080/02688699550041476 · Cited by 41

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress

Saijo, H., Hirohashi, Y., Torigoe, T., Horibe, R., Takaya, A., Murai, A., Kubo, T., Kajiwara, T., Tanaka, T., Shionoya, Y., et al. (2016) · Oncotarget · doi:10.18632/oncotarget.10571 · Cited by 40

p53: more research and more questions

Braithwaite, A. W., & Prives, C. L. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401938 · Cited by 40

Expression of Bcl‐2 and p53 protein in resectable invasive ductal carcinoma of the pancreas: Effects on clinical outcome and efficacy of adjuvant chemotherapy

Nio, Y., Dong, M., Iguchi, C., Yamasawa, K., Toga, T., Itakura, M., & Tamura, K. (2001) · Journal of Surgical Oncology · doi:10.1002/jso.1033 · Cited by 40

Alterations of oncogenes and tumor suppressor genes in esophageal cancer in China

Lu, S. (2000) · Mutation Research/Reviews in Mutation Research · doi:10.1016/s1383-5742(00)00023-5 · Cited by 40

Lessons from our children

Donaldson, S. S. (1993) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(93)90487-g · Cited by 40

Oncogenes and anti-oncogenes

Cooper, J. A. (1990) · Current Opinion in Cell Biology · doi:10.1016/0955-0674(90)90021-6 · Cited by 40

Growth factors and oncogenes in breast cancer

Gullick, W. J. (1990) · Progress in Growth Factor Research · doi:10.1016/0955-2235(90)90006-6 · Cited by 40

Role of p53 in Regulating Radiation Responses

Okazaki, R. (2022) · Life · doi:10.3390/life12071099 · Cited by 40

Anti-p53 antibodies in serum: relationship to tumor biology and prognosis of breast cancer patients

Kulić, A., Sirotković-Skerlev, M., Ćosić, S. J., Herceg, D., Kovač, Z., & Vrbanec, D. (2009) · Medical Oncology · doi:10.1007/s12032-009-9301-1 · Cited by 39

Restoration of Wild‐Type p53 Function in Human Tumors: Strategies for Efficient Cancer Therapy

Wiman, K. G. (2007) · Advances in cancer research · doi:10.1016/s0065-230x(06)97014-6 · Cited by 40

Expression of bcl‐2, p53 and Ki‐67 in arsenical skin cancers

Chang, C., Tsai, R., Chen, G., Yu, H., & Chai, C. (1998) · Journal of Cutaneous Pathology · doi:10.1111/j.1600-0560.1998.tb01775.x · Cited by 39

Expression of the p53 Gene and Apoptosis in Gestational Trophoblastic Disease

Halperin, R., PELLER, S., Sandbank, J., Bukovsky, I., & Schneider, D. (2000) · Placenta · doi:10.1053/plac.1999.0442 · Cited by 39

Oncogenes and Antioncogenes in Lung Tumorigenesis

Giaccone, G. (1996) · CHEST Journal · doi:10.1378/chest.109.5_supplement.130s · Cited by 39

A splicing mutation accounts for the lack of p53 gene expression in a CML blast crisis cell line: a novel mechanism of p53 gene inactivation

Foti, A., Bar‐Eli, M., Ahuja, H., & Cline, M. J. (1990) · British Journal of Haematology · doi:10.1111/j.1365-2141.1990.tb07849.x · Cited by 39

p53 expression in anaplastic carcinomas arising from thyroid papillary carcinomas.

Matías‐Guiu, X., Cuatrecasas, M., Musulén, E., & Prat, J. (1994) · Journal of Clinical Pathology · doi:10.1136/jcp.47.4.337 · Cited by 39

Cellular oncogenes and suppressor genes as prognostic markers in cancer

Duffy, M. J. (1993) · Clinical Biochemistry · doi:10.1016/0009-9120(93)80007-h · Cited by 39

Function and Sequence Analyses of Tumor Suppressor Gene p53 of CHO.K1 Cells

Tzang, B., Lai, Y., Hsu, M., Chang, H., Chang, C., Huang, P. C., & Liu, Y.-C. (1999) · DNA and Cell Biology · doi:10.1089/104454999315376 · Cited by 39

Targeting p53 for adoptive T-cell immunotherapy.

McCarty, T. M., Liu, X., Sun, J., Peralta, E. A., Diamond, D. J., & Ellenhorn, J. D. I. (1998) · PubMed · Cited by 39

Detection of p53 Gene Mutations in Human Ovarian and Endometrial Cancers by Polymerase Chain Reaction‐Single Strand Conformation Polymorphism Analysis

Naito, M. F., Satake, M., Sakai, E., Hirano, Y., Tsuchida, N., Kanzaki, H., Ito, Y., & Mori, T. (1992) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1992.tb02717.x · Cited by 39

Binding of p53 and p105-RB is not sufficient for oncogenic transformation by a hybrid polyomavirus-simian virus 40 large T antigen

Manfredi, J. J., & Prives, C. L. (1990) · Journal of Virology · doi:10.1128/jvi.64.11.5250-5259.1990 · Cited by 39

p53 in the anticancer mechanism of vitamin E

SCHWARTZ, J. L., Shklar, G., & Trickler, D. P. (1993) · European Journal of Cancer Part B Oral Oncology · doi:10.1016/0964-1955(93)90055-j · Cited by 39

Chemoprevention of digestive organs carcinogenesis by natural product protocatechuic acid

Tanaka, T., Kojima, T., Kawamori, T., & Mori, H. (1995) · Cancer · doi:10.1002/1097-0142(19950315)75:6+ · Cited by 79

Markers of the metastatic phenotype in prostate cancer

Foster, C. S., McLoughlin, J., Bashir, I., & Abel, P. D. (1992) · Human Pathology · doi:10.1016/0046-8177(92)90084-g · Cited by 39

p53 protein in low-grade astrocytomas: a study with long-term follow-up

Iuzzolino, P., Ghimenton, C., Nicolato, A., Giorgiutti, F., Fina, P., Doglioni, C., & Barbareschi, M. (1994) · British Journal of Cancer · doi:10.1038/bjc.1994.107 · Cited by 39

Protein synthesis—dependent cytoplasmic translocation of p53 protein after serum stimulation of growth‐arrested MCF‐7 cells

Takahashi, K., Sumimoto, H., Suzuki, K., & Ono, T. (1993) · Molecular Carcinogenesis · doi:10.1002/mc.2940080112 · Cited by 39

Prognostic factors in NSCLC. Recent experiences

van Zandwijk, N., Mooi, W. J., & Rodenhuis, S. (1995) · Lung Cancer · doi:10.1016/0169-5002(95)00418-z · Cited by 38

ARF Tumor Suppressor Induces Mitochondria-dependent Apoptosis by Modulation of Mitochondrial Bcl-2 Family Proteins

Nakazawa, Y., Kamijo, T., Koike, K., & Noda, T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m300510200 · Cited by 38

Disruption of Oncogene/Tumor Suppressor Networks During Human Carcinogenesis

Münger, K. (2002) · Cancer Investigation · doi:10.1081/cnv-120000369 · Cited by 38

Complete association of loss of heterozygosity of chromosomes 13 and 17 in osteosarcoma

Scheffer, H., Kruize, Y. C. M., Osinga, J. A. J., Kuiken, G., Oosterhuis, J. W., Leeuw, J. A., Koops, H. S., & Buys, C. H. C. M. (1991) · Cancer Genetics and Cytogenetics · doi:10.1016/0165-4608(91)90113-9 · Cited by 38

Preferential killing of p53-deficient cancer cells by reversine

Jèmaà, M., Galluzzi, L., Kepp, O., Boilève, A., Lissa, D., Senovilla, L., Harper, F., Pierron, G., Berardinelli, F., Antoccia, A., et al. (2012) · Cell Cycle · doi:10.4161/cc.20621 · Cited by 38

Clinicopathologic characteristics and prognostic significance of EGFR and p53 mutations in surgically resected lung adenocarcinomas ≤2 cm in maximal dimension

Lin, M., Wu, C., Shih, J., Chang, Y., & Yang, P. (2014) · Journal of Surgical Oncology · doi:10.1002/jso.23628 · Cited by 37

Epidermodysplasia Verruciformis as a Model of Human Papillomavirus-lnduced Genetic Cancers: The Role of Local Immunosurveillance

Majewski, S., & Jabłońska, S. (1992) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199209000-00006 · Cited by 37

RNA polymerase III transcription can be derepressed by oncogenes or mutations that compromise p53 function in tumours and Li-Fraumeni syndrome

Stein, T., Crighton, D., Boyle, J. M., Varley, J. M., & White, R. J. (2002) · Oncogene · doi:10.1038/sj.onc.1205372 · Cited by 37

p53: functions, mutations and sarcomas

Hung, J. Y., & Anderson, R. L. (1997) · Acta Orthopaedica Scandinavica · doi:10.1080/17453674.1997.11744705 · Cited by 37

The p53 tumor suppressor gene

Soussi, T. (1995) · Advances in genome biology · doi:10.1016/s1067-5701(06)80005-7 · Cited by 37

Large E1B proteins of adenovirus types 5 and 12 have different effects on p53 and distinct roles in cell transformation

van den Heuvel, S., van Laar, T., The, I., & van der Eb, A. J. (1993) · Journal of Virology · doi:10.1128/jvi.67.9.5226-5234.1993 · Cited by 37

Proliferating cell nuclear antigen and p53 expression as prognostic factors in T1‐2MO prostatic adenocarcinoma

Vesalainen, S., Lipponen, P., Talja, M. T., Alhava, E. M., & Syrjänen, K. J. (1994) · International Journal of Cancer · doi:10.1002/ijc.2910580226 · Cited by 37

Low incidence of p53 mutations in European hepatocellular carcinomas with heterogeneous mutation as a rare event

Kubicka, S., Trautwein, C., Schrem, H., Tillmann, H. L., & Manns, M. P. (1995) · Journal of Hepatology · doi:10.1016/0168-8278(95)80199-5 · Cited by 37

Biomarkers in upper aerodigestive tract tumorigenesis: a review.

Shin, D. M., Hittelman, W. N., & Hong, W. K. (1994) · PubMed · Cited by 37

E2F-1 induces the stabilization of p53 but blocks p53-mediated transactivation

Nip, J., Strom, D. K., Eischen, C. M., Cleveland, J. L., Zambetti, G. P., & Hiebert, S. W. (2001) · Oncogene · doi:10.1038/sj.onc.1204171 · Cited by 37

Allelic losses at chromosome 17p in human renal cell carcinoma are inversely related to allelic losses at chromosome 3p.

Ogawa, O., Habuchi, T., Kakehi, Y., Koshiba, M., Sugiyama, T., & Yoshida, O. (1992) · PubMed · Cited by 37

Isolation and Characterization of DNA Sequences That Are Specifically Bound by Wild-Type p53 Protein

Foord, O., Navot, N., & Rotter, V. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.3.1378 · Cited by 37

Negative auto-regulators trap p53 in their web

Zhou, X. Y., Cao, B., & Lu, H. (2017) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjx001 · Cited by 37

Silibinin Enhances Ultraviolet B-Induced Apoptosis in MCF-7 Human Breast Cancer Cells

Noh, E.-M., Yi, M. S., Youn, H. J., Lee, B. K., Lee, Y.-R., Han, J.-H., Yu, H., Kim, J., & Jung, S. H. (2011) · Journal of Breast Cancer · doi:10.4048/jbc.2011.14.1.8 · Cited by 36

Symptom reporting in cancer patients: The role of negative affect and experienced social stigma

Koller, M. T., Kussman, J., Lorenz, W., Jenkins, M., Voß, M., Arens, E. R., Richter, E., & Rothmund, Μ. (1996) · Cancer · doi:10.1002/(sici)1097-0142(19960301)77:5 · Cited by 147

Tumor Necrosis Factor-α Induces p53-dependent Apoptosis in Rat Glioma Cells

Yin, D., Kondo, S., Barnett, G. H., Morimura, T., & Takeuchi, J. (1995) · Neurosurgery · doi:10.1227/00006123-199510000-00021 · Cited by 36

Significance of p53 overexpression in urinary bladder transitional cell carcinoma in situ before and after bacillus Calmette-Guérin treatment

Ick, K., Schultz, M., Stout, P., & Fan, K. (1997) · Urology · doi:10.1016/s0090-4295(96)00624-3 · Cited by 36

Frequent loss of 11p13 and 11p15 loci in male germ cell tumours

Lothe, R. A., Hastie, N. D., Heimdal, K., Fosså, S. D., Stenwig, A. E., & Børresen‐Dale, A. (1993) · Genes Chromosomes and Cancer · doi:10.1002/gcc.2870070206 · Cited by 36

The emerging picture of p53

Selter, H., & Montenarh, M. (1994) · International Journal of Biochemistry · doi:10.1016/0020-711x(94)90139-2 · Cited by 36

Coexpression of HER-2/neu and p53 is associated with a shorter disease-free survival in node-positive breast cancer patients

Wiltschke, C., Kindås-Mügge, I., Steininger, A., Reiner, A., Reiner, G. C. A., & Preis, P. (1994) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf01194273 · Cited by 36

p53 quantitative immunocytochemical analysis in breast carcinomas*1

Charpin, C. (1995) · Human Pathology · doi:10.1016/0046-8177(95)90032-2 · Cited by 36

p53 protein expression in cutaneous T-cell lymphomas

Lauritzen, A. F., Vejlsgaard, G. L., HOU-JENSEN, K., & Ralfkiaer, E. M. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1995.tb02488.x · Cited by 36

p53 domains: suppression, transformation, and transactivation.

Reed, M. J., Wang, Y., Mayr, G. A., Me, A., Schwedes, J. F., & Tegtmeyer, P. (1993) · Europe PMC (PubMed Central) · Cited by 36

Disruption of the function of tumor-suppressor gene p53 by the hepatitis B virus X protein and hepatocarcinogenesis

Takada, S., Tsuchida, N., Kobayashi, M., & Koike, K. (1995) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/bf01197776 · Cited by 36

p53: Its Mutations and Their Impact on Transcription

Vaughan, C. A., Pearsall, I., Yeudall, W. A., Deb, S. P., & Deb, S. (2014) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-017-9211-0_4 · Cited by 37

Functional and gene network analyses of transcriptional signatures characterizing pre-weaned bovine mammary parenchyma or fat pad uncovered novel inter-tissue signaling networks during development

Piantoni, P., Bionaz, M., Graugnard, D. E., Daniels, K. M., Everts, R. E., Rodriguez‐Zas, S. L., Lewin, H. A., Hurley, H. L., Akers, M. R., & Loor, J. J. (2010) · BMC Genomics · doi:10.1186/1471-2164-11-331 · Cited by 36

The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants.

Miller, M., Shirole, N. H., Tian, R., Pal, D., & Sordella, R. (2016) · PubMed · Cited by 35

Is p53 gene mutation an indicatior of the biological behaviors of recurrence of hepatocellular carcinoma?

Sheen, I. (2003) · World Journal of Gastroenterology · doi:10.3748/wjg.v9.i6.1202 · Cited by 35

The reovirus cell attachment protein possesses two independently active trimerization domains: Basis of dominant negative effects

Leone, G. W., Maybaum, L., & Lee, P. W. K. (1992) · Cell · doi:10.1016/0092-8674(92)90516-f · Cited by 35

Immunohistochemical and mutational analysis of p53 tumor suppressor gene in gestational trophoblastic disease: correlation with mdm2, proliferation index, and clinicopathologic parameters

Cheung, A., Shen, Khoo, U., CHIU, TIN, Chung, & Ngan, H. (1999) · International Journal of Gynecological Cancer · doi:10.1046/j.1525-1438.1999.09904.x · Cited by 35

p53, c-myc p62 and proliferating cell nuclear antigen (PCNA) expression in non-Hodgkin's lymphomas.

Korkolopoulou, P., Oates, J., Kittas, C. N., & Crocker, J. (1994) · Journal of Clinical Pathology · doi:10.1136/jcp.47.1.9 · Cited by 35

Analysis of p53 gene mutations in acute myeloid leukemia

Trecca, D., Longo, L., Biondi, A., Cro, L., Calori, R., Grignani, F., Maiolo, A. T., Pelicci, P. G., & Neri, A. (1994) · American Journal of Hematology · doi:10.1002/ajh.2830460409 · Cited by 35

Neoangiogenesis and Relationship to Nuclear p53 Accumulation and Vascular Endothelial Growth Factor Expression in Advanced Gastric Carcinoma

Saito, H., Tujitani, S., Ikeguchi, M., Maeta, M., & Kaibara, N. (1999) · Oncology · doi:10.1159/000012025 · Cited by 35

p53 Gene Mutations in Esophageal Cancer Detected by Polymerase Chain Reaction Single‐strand Conformation Polymorphism Analysis

Tamura, G., Maesawa, C., Suzuki, Y. A., Satodate, R., Ishida, K., & Saito, K. (1992) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1992.tb00125.x · Cited by 35

Delineation of human papillomavirus type 18 enhancer binding proteins: the intracellular distribution of a novel octamer binding protein p92 is cell cycle regulated

Royer, H. D., Freyaldenhoven, M. P., Napierski, I., Spitkovsky, D. D., Bauknecht, T., & Dathan, N. A. (1991) · Nucleic Acids Research · doi:10.1093/nar/19.9.2363 · Cited by 35

The properties of p53 proteins selected for the loss of suppression of transformation.

Olson, D., & Levine, A. J. (1994) · PubMed · Cited by 23

Wild-type p53 can inhibit oncogene-mediated focus formation.

Eliyahu, D., Michalovitz, D., Eliyahu, S., Pinhasi-Kimhi, O., & Oren, M. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.22.8763 · Cited by 687

The p53 tumor suppressor gene and gene product.

Levine, A. J. (1989) · PubMed · Cited by 57

Transcriptional Activation by Wild-Type but Not Transforming Mutants of the p53 Anti-Oncogene

Raycroft, L., Wu, H., & Lozano, G. (1990) · Science · doi:10.1126/science.2144364 · Cited by 620

Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation

Hinds, P. W., Finlay, C. A., & Levine, A. J. (1989) · Journal of Virology · doi:10.1128/jvi.63.2.739-746.1989 · Cited by 595