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Do the poly(A) tail and 3’ untranslated region control mRNA translation?
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“Retroviruses use the host transcriptional machinery to transcribe, cap [add a methyl guanosine (G) group at the 5′ end], and polyadenylate viral mRNAs at the 3′ end, including gRNA.”
From Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication (2026) · cites this paper as Jackson and Standart 1990
In the citing paper
“In a eukaryotic cell, all these steps are obligatorily required for nuclear export of the RNAs and their subsequent translation (Jackson and Standart 1990, Eckner et al. 1991, Sachs 1993).”
From Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication (2026) · cites this paper as Jackson and Standart 1990
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Research works printed but not linked: 63
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Metadata
- Authors
- Jackson, R. J., & Standart, N.
- Affiliations
- University of Cambridge (GB)
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 1990-07
- Volume
- 62
- Issue
- 1
- Pages
- 15-24
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2054694895
- Cited by
- 590
- References
- 0
- Citations by year
- 2025: 6 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 3 · 2017: 3 · 2015: 5 · 2014: 2 · 2013: 2 · 2012: 6
- FWCI
- 7.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA Research and Splicing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › PI3K/AKT/mTOR signaling in cancer
- Keywords
- poly(A) tail, 3' untranslated region, mRNA translation, translational regulation, mRNA stability, polyadenylation
- MeSH terms
- Animals, Base Sequence, Carrier Proteins, Molecular Sequence Data, Poly A, RNA, Messenger, Protein Biosynthesis, Poly(A)-Binding Proteins
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