The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Chomczynski, P., & Sacchi, N. (1987) · Analytical Biochemistry · doi:10.1006/abio.1987.9999 · Cited by 65,515

A simple and very efficient method for generating cDNA libraries

Gubler, U., & Hoffman, B. J. (1983) · Gene · doi:10.1016/0378-1119(83)90230-5 · Cited by 4,461

Rapid detection of octamer binding proteins with ‘mini extracts’, prepared from a small number of cells

Schreiber, E. H., Matthias, P., Müller, M. M., & Schaffner, W. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.15.6419 · Cited by 4,179

A rapid boiling method for the preparation of bacterial plasmids

Holmes, D. S., & Quigley, M. E. (1981) · Analytical Biochemistry · doi:10.1016/0003-2697(81)90473-5 · Cited by 3,198

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

Sundström, C., & Nilsson, K. (1976) · International Journal of Cancer · doi:10.1002/ijc.2910170504 · Cited by 2,409

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

Bradley, T., & Metcalf, D. (1966) · Immunology and Cell Biology · doi:10.1038/icb.1966.28 · Cited by 1,938

The Human Hematopoietic Colony-Stimulating Factors

Clark, S., & Kamen, R. (1987) · Science · doi:10.1126/science.3296190 · Cited by 1,630

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

Collins, S. J., Ruscetti, F. W., Gallagher, R. E., & Gallo, R. C. (1978) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.75.5.2458 · Cited by 1,594

A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization

Sukhatme, V. P., Cao, X., Chang, L. C., Tsai‐Morris, C., Stamenkovich, D., Ferreira, P. C. P., Cohén, D., Edwards, S. A., Shows, T. B., Curran, T., et al. (1988) · Cell · doi:10.1016/0092-8674(88)90485-0 · Cited by 1,249

A Nerve Growth Factor-Induced Gene Encodes a Possible Transcriptional Regulatory Factor

Milbrandt, J. (1987) · Science · doi:10.1126/science.3672127 · Cited by 1,202

Functional characterization of the promoter for the gene encoding human eosinophil peroxidase.

Yamaguchi, Y., Zhang, D., Sun, Z., Albee, E., Nagata, S., Tenen, D. G., & Ackerman, S. J. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32184-1 · Cited by 37

From Apoptosis to Autoimmunity: Insights from the Signaling Pathways Leading to Proliferation or to Programmed Cell Death

Baixerás, E., Boscá, L., Stauber, C., González-Garcı́a, A., Carrera, A. C., Gonzalo, J. A., & Martínez‐A, C. (1994) · Immunological Reviews · doi:10.1111/j.1600-065x.1994.tb00883.x · Cited by 37

TRANSLOCATION OF THE RARα LOCUS TO THE PML OR PLZF GENE IN ACUTE PROMYELOCYTIC LEUKAEMIA

Zelent, A. (1994) · British Journal of Haematology · doi:10.1111/j.1365-2141.1994.tb04773.x · Cited by 37

Constitutive c- ets 2 Expression in M1D+ Myeloblast Leukemic Cells Induces Their Differentiation to Macrophages

Aperlo, C., Pognonec, P., Stanley, E. R., & Boulukos, K. E. (1996) · Molecular and Cellular Biology · doi:10.1128/mcb.16.12.6851 · Cited by 36

Allele-selective RUNX1 binding regulates P1 blood group status by transcriptional control of A4GALT

Westman, J. S., Stenfelt, L., Vidovic, K., Möller, M., Hellberg, Å., Kjellström, S., & Olsson, M. L. (2018) · Blood · doi:10.1182/blood-2017-08-803080 · Cited by 35

let-7 coordinates the transition to adulthood through a single primary and four secondary targets

Aeschimann, F., Neagu, A., Rausch, M., & Großhans, H. (2019) · Life Science Alliance · doi:10.26508/lsa.201900335 · Cited by 35

Myeloblastic leukemia cells conditionally blocked by myc-estrogen receptor chimeric transgenes for terminal differentiation coupled to growth arrest and apoptosis

Selvakumaran, M., Liebermann, D. A., & Hoffman‐Liebermann, B. (1993) · Blood · doi:10.1182/blood.v81.9.2257.2257 · Cited by 35

Egr-1 abrogates the block imparted by c-Myc on terminal M1 myeloid differentiation

Shafarenko, M., Liebermann, D. A., & Hoffman‐Liebermann, B. (2005) · Blood · doi:10.1182/blood-2004-08-3056 · Cited by 34

The human zinc finger protein EGR-4 acts as autoregulatory transcriptional repressor

Zipfel, P. F., Decker, E. L., Holst, C., & Skerka, C. (1997) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(97)00084-5 · Cited by 34

Monocytic differentiation of HL-60 promyelocytic leukemia cells correlates with the induction of Bcl-xL.

Chatterjee, D., Han, Z., Mendoza, J., Goodglick, L., Hendrickson, E. A., Pantazis, P., & Wyche, J. H. (1997) · PubMed · Cited by 34

Regulation of macrophage gene expression by T-cell-derived lymphokines.

Ohmori, Y., & Hamilton, T. A. (1994) · Pharmacology and Therapeutics · doi:10.1016/0163-7258(94)90026-4 · Cited by 46

Growth arrest and terminal differentiation of leukemic myelomonocytic cells induced through ligation of surface CD23 antigen

Ouaaz, F., Sola, B., Issaly, F., Kolb, J., Davi, F., Mentz, F., Arock, M., Paul‐Eugène, N., Körner, M., & Dugas, B. (1994) · Blood · doi:10.1182/blood.v84.9.3095.3095 · Cited by 34

TGF-β1 stimulates cultured human fibroblasts to proliferate and produce tissue-like fibroplasia: A fibronectin matrix-dependent event

Clark, R. A. F., McCoy, G. A., Folkvord, J. M., & McPherson, J. M. (1997) · Journal of Cellular Physiology · doi:10.1002/(sici)1097-4652(199701)170:1 · Cited by 212

Wilms' Tumor Gene Product WT1 Arrests Macrophage Differentiation of HL-60 Cells Through Its Zinc-Finger Domain

Deuel, T. F., Guan, L., & Wang, Z. (1999) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9896 · Cited by 33

Resistance to phorbol ester-induced differentiation of a U-937 myeloid leukemia cell variant with a signaling defect upstream to Raf-1 kinase.

Hass, R., Hirano, T., Kharbanda, S. M., Rubin, E. H., Meinhardt, G., & Kufe, D. W. (1993) · PubMed · Cited by 33

Characterization of cis-Acting Sequences and trans-Acting Signals Regulating Early Growth Response 1 and c-fos Promoters Through the Granulocyte-Macrophage Colony-Stimulating Factor Receptor in BA/F3 Cells

Watanabe, S., Kubota, H., Sakamoto, K. M., & Arai, K. (1997) · Blood · doi:10.1182/blood.v89.4.1197 · Cited by 33

Chromosomal Deletions in Myelodysplasia

Boultwood, J., & Fidler, C. (1995) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428199509051705 · Cited by 33

The Zebrafish egr1 Gene Encodes a Highly Conserved, Zinc-Finger Transcriptional Regulator

Drummond, I. A. S., Rohwer-Nutter, P., & Sukhatme, V. P. (1994) · DNA and Cell Biology · doi:10.1089/dna.1994.13.1047 · Cited by 32

Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis

Carl, M., Akagi, Y., Weidner, S., Isaka, Y., Imai, E., & Rupprecht, H. (2003) · Kidney International · doi:10.1046/j.1523-1755.2003.00865.x · Cited by 32

Nerve growth factor induces expression of immediate-early genes NGFI-A (Egr-1) and NGFI-B (nur 77) in adult rat dorsal root ganglion neurons

Kendall, G. S., Ensor, E. A., Brar-Rai, A., Winter, J., & Latchman, D. S. (1994) · Molecular Brain Research · doi:10.1016/0169-328x(94)90280-1 · Cited by 32

EZH2 overexpression dampens tumor-suppressive signals via an EGR1 silencer to drive breast tumorigenesis

Guan, X., Deng, H., Choi, U. L., Li, Z., Yang, Y., Zeng, J., Liu, Y., Zhang, X., & Li, G. (2020) · Oncogene · doi:10.1038/s41388-020-01484-9 · Cited by 32

Down-regulation of Hox A7 is required for cell adhesion and migration on fibronectin during early HL-60 monocytic differentiation

Leroy, P., Berto, F., Bourget, I., & Rossi, B. (2004) · Journal of Leukocyte Biology · doi:10.1189/jlb.0503246 · Cited by 31

Comprehensive Integration of Single-Cell Transcriptional Profiling Reveals the Heterogeneities of Non-cardiomyocytes in Healthy and Ischemic Hearts

Zhuang, L., Lu, L., Zhang, R., Chen, K., & Yan, X. (2020) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2020.615161 · Cited by 29

Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

Young, D. J., Stoddart, A., Nakitandwe, J., Chen, S.-C., Qian, Z. Y., Downing, J. R., & Beau, M. M. L. (2014) · Haematologica · doi:10.3324/haematol.2013.098657 · Cited by 30

Role of early growth response 1 in arteriogenesis: Impact on vascular cell proliferation and leukocyte recruitment in vivo

Ziegelhoeffer, T., Heil, M., Fischer, S., Fernández, B., Schaper, W. K. A., Preissner, K. T., Deindl, E., & Pagel, J.-I. (2012) · Thrombosis and Haemostasis · doi:10.1160/th11-07-0490 · Cited by 30

CAL72: a human osteosarcoma cell line with unique effects on hematopoietic cells

Rochet, N., Leroy, P., Far, D. F., Ollier, L., Loubat, A., & Rossi, B. (2003) · European Journal Of Haematology · doi:10.1034/j.1600-0609.2003.02766.x · Cited by 30

Lipopolysaccharide Induction of THP-1 Cells Activates Binding of c-Jun, Ets, and Egr-1 to the Tissue Factor Promoter

Groupp, E. R., & Donovan-Peluso, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.21.12423 · Cited by 30

Early growth response transcription factor EGR‐1 regulates Gαq gene in megakaryocytic cells

Jalagadugula, G. S., Dhanasekaran, D. N., KIM, S., Kunapuli, S. P., & Rao, A. K. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.02229.x · Cited by 29

Regulation of expression of the early growth response gene-1 (EGR-1) in malignant and benign cells of the prostate

Mora, G. R., Olivier, K. R., Mitchell, R. F., Jenkins, R. B., & Tindall, D. J. (2004) · The Prostate · doi:10.1002/pros.20153 · Cited by 29

WT1/EGR1-mediated control of STIM1 expression and function in cancer cells

Michael, F. R. (2011) · Frontiers in bioscience · doi:10.2741/3862 · Cited by 29

Expression of the zinc finger Egr1 gene during zebrafish embryonic development

Close, R., Toro, S., MARTIAL, J. A., & Müller, M. (2002) · Mechanisms of Development · doi:10.1016/s0925-4773(02)00283-6 · Cited by 28

The Wilms' tumor suppressor, WT1, inhibits 12-O-tetradecanoylphorbol-13-acetate activation of the multidrug resistance-1 promoter.

McCoy, C., McGee, S. B., & Cornwell, M. M. (1999) · PubMed · Cited by 28

Paroxysmal nocturnal hemoglobinuria

Lyakisheva, A., Felda, O., Ganser, A., Schmidt, R. E., & Schubert, J. E. A. (2002) · Experimental Hematology · doi:10.1016/s0301-472x(01)00763-9 · Cited by 28

Involvement of the NGFI‐A gene in the differentiation of neuroblastoma cells

Pignatelli, M., Cortés‐Canteli, M., Santos, Á., & Pérez‐Castillo, A. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)01420-9 · Cited by 28

Single-cell analysis reveals immune cell abnormalities underlying the clinical heterogeneity of patients with systemic sclerosis

Shimagami, H., Nishimura, K., Matsushita, H., Metsugi, S., Kato, Y., Kawasaki, T., Tsujimoto, K., Edahiro, R., Itotagawa, E., Naito, M., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-60034-7 · Cited by 30

Goldfish (Carassius auratus L.) as a model system to study the growth factors, receptors and transcription factors that govern myelopoiesis in fish

Katzenback, B. A., Katakura, F., & Belosevic, M. (2015) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2015.10.024 · Cited by 28

A cryptic deletion in 5q31.2 provides further evidence for a minimally deleted region in myelodysplastic syndromes

MacKinnon, R. N., Kannourakis, G., Wall, M., & Campbell, L. J. (2011) · Cancer Genetics · doi:10.1016/j.cancergen.2011.02.001 · Cited by 27

ZK7, a novel zinc finger gene, is induced by vascular endothelial growth factor and inhibits apoptotic death in hematopoietic cells.

Kuramoto, K., Uesaka, T., Kimura, A., Kobayashi, M., Watanabe, H., & Katoh, O. (2000) · PubMed · Cited by 27

Expression of the transcriptional regulator Egr-1 in experimental glomerulonephritis: Requirement for mesangial cell proliferation

Rupprecht, H., Höfer, G., de Heer, E., Sterzel, R. B., Faller, G., & Schoechklmann, H. O. (1997) · Kidney International · doi:10.1038/ki.1997.100 · Cited by 27

Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation

Coccia, E. M., Stellacci, E., Valtieri, M., Masella, B., Feccia, T., Marziali, G., Hiscott, J. B., Testa, U., Peschle, C., & Battistini, A. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3600285 · Cited by 27

A cardiotonic steroid bufalin-induced differentiation of THP-1 cells

Numazawa, S., Inoue, N., Nakura, H., Sugiyama, T.-I., Fujino, E., Shinoki, M.-A., Yoshida, T., & Kuroiwa, Y. (1996) · Biochemical Pharmacology · doi:10.1016/0006-2952(96)00210-9 · Cited by 27

The proto-oncogene c-myc blocks myeloid differentiation independently of its target gene ornithine decarboxylase

Selvakumaran, M., Liebermann, D. A., & Hoffman‐Liebermann, B. (1996) · Blood · doi:10.1182/blood.v88.4.1248.bloodjournal8841248 · Cited by 27

Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice

Tamura, A., Hirai, H., Yokota, A., Sato, A., Shoji, T., Kashiwagi, T., Iwasa, M., Fujishiro, A., Miura, Y., & Maekawa, T. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.07.045 · Cited by 26

The Early Growth Response Factor-1 Is Involved in Stem Cell Factor (SCF)-induced Interleukin 13 Production by Mast Cells, but Is Dispensable for SCF-dependent Mast Cell Growth

Li, B., Berman, J. N., Tang, J., & Lin, T. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610859200 · Cited by 25

Silencing of OSBP-related protein 8 (ORP8) modifies the macrophage transcriptome, nucleoporin p62 distribution, and migration capacity

Béaslas, O., Vihervaara, T., Li, J., Laurila, P., Yan, D., & Olkkonen, V. M. (2012) · Experimental Cell Research · doi:10.1016/j.yexcr.2012.05.026 · Cited by 25

Inflammation-Induced Epithelial-to-Mesenchymal Transition and GM-CSF Treatment Stimulate Mesenteric Mesothelial Cells to Transdifferentiate into Macrophages

Katz, S., Zsiros, V., Dóczi, N., & Kiss, A. L. (2018) · Inflammation · doi:10.1007/s10753-018-0825-4 · Cited by 25

Transcriptional regulation of human survivin by early growth response (Egr)‐1 transcription factor

Wagner, M., Schmelz, K., Dörken, B., & Tamm, I. (2007) · International Journal of Cancer · doi:10.1002/ijc.23183 · Cited by 25

Characterization of inherited scavenger receptor overexpression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas.

Giry, C., Giroux, L.-M., Roy, M., Davignon, J., & Minnich, A. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)39127-6 · Cited by 25

cDNA cloning and expression analysis of mouse zf9, a Krüppel-like transcription factor gene that is induced by adipogenic hormonal stimulation in 3T3-L1 cells

Inuzuka, H., Wakao, H., Masuho, Y., Muramatsu, M.-A., Tojo, H., & Nanbu-Wakao, R. (1999) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression · doi:10.1016/s0167-4781(99)00161-x · Cited by 24

Post‐transcriptional effects of phorbol 12‐myristate 13‐acetate on transcriptome of U937 cells

Kitamura, H., Nakagawa, T., Takayama, M., Kimura, Y., Hijika, A., & Ohara, O. (2004) · FEBS Letters · doi:10.1016/j.febslet.2004.11.008 · Cited by 24

Repression of the HSV-1 latency-associated transcript (LAT) promoter by the early growth response (EGR) proteins: Involvement of a binding site immediately downstream of the TATA box

Tatarowicz, W. A., Martin, C. E., Pekosz, A. S., Madden, S. L., Rauscher, F. J., Chiang, S.-Y., Beerman, T. A., & Fraser, N. W. (1997) · Journal of NeuroVirology · doi:10.3109/13550289709018296 · Cited by 24

Growth of LLC-PK1 renal cells is mediated by EGR-1 up-regulation of G protein alpha i-2 protooncogene transcription.

Kinane, T. B., Finder, J. D., Kawashima, A., Brown, D., Abbate, M., Shang, C., Fredericks, W. J., Rauscher, F. J., Sukhatme, V. P., & Ercolani, L. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47013-5 · Cited by 24

Automatic identification of informative regions with epigenomic changes associated to hematopoiesis

Pau, E. C. D. S., Juan, D., Pancaldi, V., Were, F., Martín-Subero, J. I., Rico, D., & Valencia, A. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx618 · Cited by 24

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα

Ramberger, E., Sapozhnikova, V., Kowenz‐Leutz, E., Zimmermann, K., Nicot, N., Nazarov, P. V., Pérez-Hernández, D., Reimer, U., Mertins, P., Dittmar, G., et al. (2021) · iScience · doi:10.1016/j.isci.2021.102686 · Cited by 24

Copper-induced apoptosis and immediate early gene expression in macrophages

Pang, J. S., & Chau, L. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(99)00126-4 · Cited by 23

Suppression of transcription factor early growth response 1 reduces herpes simplex virus lethality in mice

Chen, S., Yao, H.-W., Chen, I.-T., Shieh, B., Li, C. L., & Chen, S. (2008) · Journal of Clinical Investigation · doi:10.1172/jci35114 · Cited by 23

Induction of Early Growth Response-1 Mediates Microglia Activation In Vitro But is Dispensable In Vivo

Langmann, T., Ebert, S., Walczak, Y., Weigelt, K., Ehrengruber, M. U., Stiewe, T., & Weber, B. H. F. (2009) · NeuroMolecular Medicine · doi:10.1007/s12017-009-8061-6 · Cited by 22

Distribution and expression analysis of transcription factors in tissues and progenitor cell populations of the goldfish (Carassius auratus L.) in response to growth factors and pathogens

Katzenback, B. A., Karpman, M., & Belosevic, M. (2011) · Molecular Immunology · doi:10.1016/j.molimm.2011.03.007 · Cited by 23

Leukemia suppressor function of Egr-1 is dependent on transforming oncogene

Gibbs, J. D., Liebermann, D. A., & Hoffman‐Liebermann, B. (2008) · Leukemia · doi:10.1038/leu.2008.189 · Cited by 22

Macrophage precursor cells produce perforin and perform Yac-1 lytic activity in response to stimulation with interleukin-2

Li, H., Pohler, U., Strehlow, I., Hertig, S., Baccarini, M., Emmendörffer, A., Tschopp, J., & Lohmann‐Matthes, M. (1994) · Journal of Leukocyte Biology · doi:10.1002/jlb.56.2.117 · Cited by 22

Early Growth Response Factor 1 in Aging Hematopoietic Stem Cells and Leukemia

Kulkarni, R. S. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.925761 · Cited by 21

SP500263, a novel SERM, blocks osteoclastogenesis in a human bone cell model: role of IL-6 and GM-CSF

Sutherland, M. K. (2003) · Cytokine · doi:10.1016/s1043-4666(03)00179-0 · Cited by 20

Opposite effects of inhibitors of mitogen-activated protein kinase pathways on the egr-1 and β-globin expression in erythropoietin-responsive murine erythroleukemia cells

Schaefer, A., Kósa, F., Bittorf, T., Magócsi, M., Rosche, A., Chávez, Y. R., Marotzki, S., & Marquardt, H. (2003) · Cellular Signalling · doi:10.1016/j.cellsig.2003.07.001 · Cited by 20

Recent status of the antisense oligonucleotide approaches in oncology

Ma, L., & Calvo, F. M. (1996) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.1996.tb00153.x · Cited by 20

Protein partners of C/EBPε

Chih, D. Y., Park, D. J., Gross, M. E., Idos, G., Vuong, P. T., Hirama, T., Chumakov, A. M., SAID, J. W., & Koeffler, H. P. (2004) · Experimental Hematology · doi:10.1016/j.exphem.2004.08.014 · Cited by 19

Identification of transcriptional regulatory cascades in retinoic acid-induced growth arrest of HepG2 cells

Nakanishi, M., Tomaru, Y., Miura, H., Hayashizaki, Y., & Suzuki, M. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn066 · Cited by 19

TheNab2andStat6Genes Share a Common Transcription Termination Region

Svaren, J. P., Apel, E. D., Simburger, K. S., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., & Milbrandt, J. (1997) · Genomics · doi:10.1006/geno.1997.4609 · Cited by 19

Involvement of serum response element in okadaic acid-induced EGR-1 transcription in human T-cells.

Chauhan, D., Kharbanda, S. M., Uchiyama, H., Sukhatme, V. P., Kufe, D. W., & Anderson, K. C. (1994) · PubMed · Cited by 19

Expression analysis of an Arabidopsis C2H2 zinc finger protein gene

Tague, B. W., Gallant, P., & Goodman, H. M. (1996) · Plant Molecular Biology · doi:10.1007/bf00020477 · Cited by 18

Transcriptional regulation of myeloid differentiation primary response (MyD) genes during myeloid differentiation is mediated by nuclear factor Y

Sjin, R. M. T. T., Krishnaraju, K., Hoffman‐Liebermann, B., & Liebermann, D. A. (2002) · Blood · doi:10.1182/blood.v100.1.80 · Cited by 18

Differentiation of Myeloid Cells and 1, 25-Dihydroxyvitamin D3

Takahashi, T., Nakamura, K., & Iho, S. (1997) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428199709068268 · Cited by 17

Augmented expression of P-gp/multi-drug resistance gene by all-trans retinoic acid in monocytic leukemic cells

Tokura, Y., Shikami, M., Miwa, H., Watarai, M., Sugamura, K., Wakabayashi, M., Satoh, A., Imamura, A., Mihara, H., Katoh, Y., et al. (2002) · Leukemia Research · doi:10.1016/s0145-2126(01)00094-7 · Cited by 17

The analysis of novel distal Cebpa enhancers and silencers using a transcriptional model reveals the complex regulatory logic of hematopoietic lineage specification

Bertolino, E., Reinitz, J., & Manu (2016) · Developmental Biology · doi:10.1016/j.ydbio.2016.02.030 · Cited by 18

Characterization of retinoic acid- and cell-dependent sequences which regulate zif268 gene expression in osteoblastic cells

Suva, L. J., Towler, D. A., Harada, S., Gaub, M. P., & Rodan, G. A. (1994) · Molecular Endocrinology · doi:10.1210/me.8.11.1507 · Cited by 17

Overexpression of murine WT1+/+ and −/− isoforms has no effect on chemoresistance but delays differentiation in the K562 leukemia cell line

Carrington, D. P., & Algar, E. M. (2000) · Leukemia Research · doi:10.1016/s0145-2126(00)00064-3 · Cited by 17

Frontline Science: Cxxc5 expression alters cell cycle and myeloid differentiation of mouse hematopoietic stem and progenitor cells

Joshi, H. R., Hill, H. R., Zhou, Z., He, X., Voelkerding, K. V., & Kumánovics, A. (2020) · Journal of Leukocyte Biology · doi:10.1002/jlb.1hi0120-169r · Cited by 14

Regulation of Teleost Macrophage and Neutrophil Cell Development by Growth Factors and Transcription Factors

Barbara, A., Katakura, F., & Belosevic, M. (2012) · InTech eBooks · doi:10.5772/53589 · Cited by 16

Global analysis of in vivo EGR1‐binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing

Tang, C., Shi, X., Wang, W., Zhou, D., Tu, J., Xie, X., Ge, Q., Xiao, P., Sun, X. S., & Lu, Z. (2010) · Electrophoresis · doi:10.1002/elps.201000094 · Cited by 16

MAP kinase-dependent autophagy controls phorbol myristate acetate-induced macrophage differentiation of HL-60 leukemia cells

Mandić, M., Misirkic-Marjanovic, M., Vucicevic, L. M., Jovanović, M., Bošnjak, M., Perović, V., Ristic, B. Z., Ćirić, D., Harhaji-Trajkovic, L. M., & Trajković, V. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120481 · Cited by 15

CD8 T Cell Responses to Lymphocytic Choriomeningitis Virus in Early Growth Response Gene 1-Deficient Mice

Singh, A., Svaren, J. P., Grayson, J. M., & Suresh, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.6.3855 · Cited by 16

Ischemic postconditioning downregulates Egr-1 expression and attenuates postischemic pulmonary inflammatory cytokine release and tissue injury in rats

Wu, H., Lei, S., Jiang, Y., Liu, X., Zhang, D., Gu, X., Zhang, L., & Xia, Z. (2012) · Journal of Surgical Research · doi:10.1016/j.jss.2012.07.031 · Cited by 16

The EGR1 Protein Contains a Discrete Transcriptional Regulatory Domain Whose Deletion Results in a Truncated Protein That Blocks EGR1-Induced Transcription

Carman, J., & Monroe, J. G. (1995) · DNA and Cell Biology · doi:10.1089/dna.1995.14.581 · Cited by 16

How Do Stem Cells Decide What To Do?

Cross, M. A., Heyworth, C. M., & Dexter, T. M. (2007) · Novartis Foundation symposium · doi:10.1002/9780470515280.ch2 · Cited by 16

Activation of early growth response 1 gene transcription and pp90rsk during induction of monocytic differentiation.

Kharbanda, S. M., Saleem, A., Hirano, T., Emoto, Y., Sukhatme, V. P., Blenis, J., & Kufe, D. W. (1994) · PubMed · Cited by 16

Under inflammatory stimuli mesenteric mesothelial cells transdifferentiate into macrophages and produce pro-inflammatory cytokine IL-6

Katz, S., Zsiros, V., & Kiss, A. L. (2019) · Inflammation Research · doi:10.1007/s00011-019-01247-7 · Cited by 15

New Insights in AML Biology From Genomic Analysis

Perry, A. M., & Attar, E. C. (2014) · Seminars in Hematology · doi:10.1053/j.seminhematol.2014.08.005 · Cited by 15

Cytokines in the Differentiation Therapy of Leukemia: From Laboratory Investigations to Clinical Applications

Leung, K. N., Mak, N. K., & Fung, M. C. (2005) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408360500295154 · Cited by 16

Models of lineage switching in hematopoietic development: a new myeloid-committed eosinophil cell line (YJ) demonstrates trilineage potential

Yamaguchi, Y., Nishio, H., Kasahara, T., Ackerman, S. J., Koyanagi, H., & Suda, T. (1998) · Leukemia · doi:10.1038/sj.leu.2401115 · Cited by 15

Characterization of the Human elk-1Promoter

Lehmann, U., Brocke, P., Dittmer, J., & Nordheim, A. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.3.1736 · Cited by 14

Multifaceted regulatory mechanisms of the EGR family in tumours and prospects for therapeutic applications (Review)

Guo, R., Wang, R., Zhang, W., Li, Y., Wang, Y., Wang, H., Li, X., & Song, J. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5554 · Cited by 14

Selection of down‐regulated sequences along the monocytic differentiation of leukemic HL60 cells

Herblot, S., Vekris, A., Rouzaut, A., Najeme, F., de Miguel, C., Bezian, J. H., & Bonnet, J. (1997) · FEBS Letters · doi:10.1016/s0014-5793(97)00967-8 · Cited by 14

Serotonergic 5-HT2A receptor stimulation induces steroid 5α-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1

Morita, K., Arimochi, H., & Her, S. (2005) · Molecular Brain Research · doi:10.1016/j.molbrainres.2005.05.013 · Cited by 13

B cell early response gene expression coupled to B cell receptor, CD40 and interleukin‐4 receptor co‐stimulation: evidence for a role of the egr‐2/krox20 transcription factor in B cell proliferation

Newton, J. S., Li, J., Ning, Z., Schoendorf, D., Norton, J. D., & Murphy, J. J. (1996) · European Journal of Immunology · doi:10.1002/eji.1830260413 · Cited by 13

A Role for Serine Proteases in Mediating Phorbol Ester-Induced Differentiation of HL-60 Cells

Bestilny, L. J., & Riabowol, K. T. (2000) · Experimental Cell Research · doi:10.1006/excr.2000.4821 · Cited by 13

V‐sis induces Egr‐1 expression by a pathway mediated by c‐Ha‐ras

Huang, R., Ngo, L., Okamura, D. M., Tucker, M., & Adamson, E. D. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240560407 · Cited by 13

Enhanced expression in seminoma of human zinc finger genes located on chromosome 19

Ogawa, T., Poncelet, D. A., 木下, 裕., Noce, T., Takeda, M., Kawamoto, K., Udagawa, K., Lecocq, P. J., Marine, J., MARTIAL, J. A., et al. (1998) · Cancer Genetics and Cytogenetics · doi:10.1016/s0165-4608(97)00004-6 · Cited by 12

Regulation of Osteoclastogenesis by Antisense Oligodeoxynucleotides Specific to Zinc Finger Nuclear Transcription Factors Egr-1 and WT1 in Rat Bone Marrow Culture System1

Kukita, T., Kukita, A., Harada, H., & Iijima, T. (1997) · Endocrinology · doi:10.1210/endo.138.10.5466 · Cited by 12

Prostaglandin E2 induces Egr-1 mRNA in MC3T3-E1 osteoblastic cells by a protein kinase C-dependent pathway

Fang, M. A., Noguchi, G. M., & McDougall, S. (1996) · Prostaglandins Leukotrienes and Essential Fatty Acids · doi:10.1016/s0952-3278(96)90067-8 · Cited by 12

A "Stealth" Approach to Inhibition of Lymphocyte Activation by Oligonucleotide Complementary to the Putative G 0 /G 1 Switch Regulatory Gene G0S30/EGR1/NGFI-A

Cristillo, A. D., Heximer, S. P., & Forsdyke, D. R. (1996) · DNA and Cell Biology · doi:10.1089/dna.1996.15.561 · Cited by 11

A hematopoietic organ-specific 49-kD nuclear antigen: predominance in immature normal and tumor granulocytes and detection in hematopoietic precursor cells

Lee, B., Shav‐Tal, Y., Peled, A., Gothelf, Y., Jiang, W., Toledo, J., Ploemacher, R., Haran‐Ghera, N., & Zipori, D. (1996) · Blood · doi:10.1182/blood.v87.6.2283.bloodjournal8762283 · Cited by 11

The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage. Cell 72:197–209

Krishnaraju, K., Nguyen, H. Q., Liebermann, D. A., Hoffman‐Liebermann, B., Biol, M. C., Krishnaraju, K., Nguyen, H. Q., & Liebermann, D. A. (1993)

The Zinc Finger Transcription Factor Egr-1 Activates Macrophage Differentiation in M1 Myeloblastic Leukemia Cells

Krishnaraju, K., Hoffman‐Liebermann, B., & Liebermann, D. A. (1998) · Blood · doi:10.1182/blood.v92.6.1957 · Cited by 88

The Zinc Finger Transcription Factor Egr-1 Potentiates Macrophage Differentiation of Hematopoietic Cells

Krishnaraju, K., Nguyen, H. Q., Liebermann, D. A., & Hoffman‐Liebermann, B. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.10.5499 · Cited by 122

Early Growth Response Transcriptional Regulators Are Dispensable for Macrophage Differentiation

Carter, J. H., & Tourtellotte, W. G. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.5.3038 · Cited by 56

Early growth response gene 1 stimulates development of hematopoietic progenitor cells along the macrophage lineage at the expense of the granulocyte and erythroid lineages

Krishnaraju, K., Hoffman‐Liebermann, B., & Liebermann, D. A. (2001) · Blood · doi:10.1182/blood.v97.5.1298 · Cited by 108