CoChat
Sign Up
Cited by 134

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

Common signals control low density lipoprotein receptor sorting in endosomes and the Golgi complex of MDCK cells

Matter, Karl, Whitney, J.Andrew, Yamamoto, Ellen M., Mellman, Ira·1993·Cell
DOI 10.1016/0092-8674(93)90727-8
Open this paper in CoChat — free account

Abstract

The cytoplasmic domain of the LDL receptor bears two tyrosine-containing determinants that can independently target receptors from the Golgi to the basolateral plasma membrane of MDCK cells. We found that these determinants, localized to the membrane-proximal and -distal regions of the receptor's cytoplasmic domain, also control polarized sorting in endosomes. Inactivation of the distal determinant reduced receptors' ability to return to the basolateral domain following endocytosis, resulting instead in receptor transcytosis from basolateral endosomes to the apical plasma membrane. Similarly, receptors internalized from the apical surface were transported from apical endosomes to the basolateral surface, owing to the proximal basolateral targeting determinant. Thus, receptor recycling in endosomes is directed by the same signals as polarized sorting in the Golgi, indicating that sorting on the endocytic and biosynthetic pathways involves similar mechanisms. The observation that brefeldin A interfered with sorting but not transport in both endosomes and the Golgi further supports this.

Overview

Integrity signals

Registry

Crossref · 10.1016/0092-8674(93)90727-8

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 2 references

Research works printed but not linked: 49

  1. Barties, 1987, Biogenesis of the rat hepatocyte plasma membrane in vivo: comparison of the pathways taken by apical and basolateral proteins using subcellular fractionation, J. Cell Biol., 105, 1241, 10.1083/jcb.105.3.1241 · DOI
  2. Bomsel, 1989, Endocytosis in filter-grown Madin-Darby canine kidney cells, J. Cell Biol., 109, 3243, 10.1083/jcb.109.6.3243 · DOI
  3. Breitfeld, 1989, Postendocytic sorting of the ligand for the polymeric immunoglobulin receptor in Madin-Darby canine kidney cells, J. Cell Biol., 109, 475, 10.1083/jcb.109.2.475 · DOI
  4. Breitfeld, 1990, Effect of nocodazole on vesicular traffic to the apical and basolateral surfaces of polarized MDCK cells, J. Cell Biol., 111, 2365, 10.1083/jcb.111.6.2365 · DOI
  5. Brewer, 1991, A single amino acid change in the cytoplasmic domain alters the polarized delivery of influenza virus hemagglutinin, J. Cell Biol., 114, 413, 10.1083/jcb.114.3.413 · DOI
  6. Brown, 1989, Mechanism of membrane anchoring affects polarized expression of two proteins in MDCK cells, Science, 245, 1499, 10.1126/science.2571189 · DOI
  7. Cameron, 1991, Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis, J. Cell Biol., 115, 151, 10.1083/jcb.115.1.151 · DOI
  8. Casanova, 1990, Phosphorylation of the polymeric immunoglobulin receptor required for its efficient transcytosis, Science, 248, 742, 10.1126/science.2110383 · DOI
  9. Casanova, 1991, An autonomous signal for basolateral sorting in the cytoplasmic domain of the polymeric immunoglobulin receptor, Cell, 66, 65, 10.1016/0092-8674(91)90139-P · DOI
  10. Casanova, 1991, Direct apical sorting of rat liver dipeptidylpeptidase IV expressed in MDCK cells, J. Biol. Chem., 266, 24428, 10.1016/S0021-9258(18)54246-0 · DOI
  11. Davis, 1987, The low density lipoprotein receptor: identification of amino acids in cytoplasmic domain required for rapid endocytosis, J. Biol. Chem., 262, 4075, 10.1016/S0021-9258(18)61313-4 · DOI · Paper page
  12. Donaldson, 1991, Binding of ARF and β-COP to Golgi membranes: possible regulation by a trimeric G protein, Science, 254, 1197, 10.1126/science.1957170 · DOI
  13. Felder, 1990, Kinase activity controls the sorting of the epidermal growth factor receptor within the multivesicular body, Cell, 61, 623, 10.1016/0092-8674(90)90474-S · DOI
  14. Geuze, 1987, Membranes of sorting organelles display lateral heterogeneity in receptor distribution, J. Cell Biol., 104, 1715, 10.1083/jcb.104.6.1715 · DOI
  15. Hammerton, 1991, Mechanism for regulating cell surface distribution of Na+, K+-ATPase in polarized epithelial cells, Science, 254, 847, 10.1126/science.1658934 · DOI
  16. Harter, 1992, Transport of the lysosomal membrane glycoprotein Igp120 (Igp-A) to lysosomes does not require appearance on the plasma membrane, J. Cell Biol., 117, 311, 10.1083/jcb.117.2.311 · DOI
  17. Helenius, 1983, Endosomes, Trends Biochem. Sci., 8, 245, 10.1016/0968-0004(83)90350-X · DOI
  18. Hirt, 1993, Transcytosis of the polymeric Ig receptor requires phosphorylation of serine 664 in the absence but not the presence of dimeric IgA, Cell, 74, 245, 10.1016/0092-8674(93)90416-N · DOI
  19. Hunziker, 1989, Expression of macrophage-lymphocyte Fc receptors in MDCK cells: polarity and transcytosis differ for isoforms with or without coated pit localization domains, J. Cell Biol., 109, 3291, 10.1083/jcb.109.6.3291 · DOI
  20. Hunziker, 1991, Relationships between sorting in the exocytic and endocytic pathways, Sem. Cell Biol., 2, 397
  21. Hunziker, 1990, Differential microtubule requirements for transcytosis in MDCK cells, EMBO J., 9, 3515, 10.1002/j.1460-2075.1990.tb07560.x · DOI
  22. Hunziker, 1991, Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant, Cell, 66, 907, 10.1016/0092-8674(91)90437-4 · DOI
  23. Hunziker, 1991, Selective inhibition of transcytosis by brefeldin A in MDCK cells, Cell, 67, 617, 10.1016/0092-8674(91)90535-7 · DOI
  24. Le Bivic, 1990, Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line, J. Cell Biol., 111, 1351, 10.1083/jcb.111.4.1351 · DOI
  25. Le Bivic, 1991, An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells, J. Cell Biol., 115, 607, 10.1083/jcb.115.3.607 · DOI
  26. Lewis, 1985, Glycoproteins of the lysosomal membrane, J. Cell Biol., 100, 1839, 10.1083/jcb.100.6.1839 · DOI
  27. Linstedt, 1991, Synaptophysin is sorted from endocytic markers in neuroendocrine PC12 cells but not transfected fibroblasts, Neuron, 7, 309, 10.1016/0896-6273(91)90269-6 · DOI
  28. Lisanti, 1989, A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells, J. Cell Biol., 109, 2145, 10.1083/jcb.109.5.2145 · DOI
  29. Low, 1992, Selective inhibition of protein targeting to the apical domain of MDCK cells by brefeldin A, J. Cell Biol., 118, 51, 10.1083/jcb.118.1.51 · DOI
  30. Matter, 1990, Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2), Cell, 60, 429, 10.1016/0092-8674(90)90594-5 · DOI
  31. Matter, 1990, Endocytosis, recycling, and lysosomal delivery of brush border hydrolases in cultured human intestinal epithelial cells (Caco-2), J. Biol. Chem., 265, 3503, 10.1016/S0021-9258(19)39797-2 · DOI
  32. Matter, 1992, Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants, Cell, 71, 741, 10.1016/0092-8674(92)90551-M · DOI · Paper page
  33. Mayor, 1993, Sorting of membrane components from endosomes and subsequent recycling to the cell surface occurs by a bulk flow process, J. Cell Biol., 121, 1257, 10.1083/jcb.121.6.1257 · DOI · Paper page
  34. Mellman, 1984, Internalization and rapid recycling of macrophage Fc receptors tagged with monovalent antireceptor antibody: possible role of a prelysosomal compartment, J. Cell Biol., 98, 1163, 10.1083/jcb.98.4.1163 · DOI
  35. Nelson, 1992, Regulation of cell surface polarity from bacteria to mammals, Science, 258, 948, 10.1126/science.1439806 · DOI
  36. Nelson, 1990, Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin), ankyrin, and fodrin in MDCK epithelial cells, J. Cell Biol., 110, 349, 10.1083/jcb.110.2.349 · DOI
  37. Orci, 1991, Brefeldin A, a drug that blocks secretion, prevents the assembly of non-clathrin-coated buds on Golgi cisternae, Cell, 64, 1183, 10.1016/0092-8674(91)90273-2 · DOI
  38. Orci, 1993, Budding from Golgi membranes requires the coatomer complex on non-clathrin coat proteins, Nature, 362, 648, 10.1038/362648a0 · DOI
  39. Parton, 1989, 109, 3259
  40. Podbilewicz, 1990, ATP and cytosol requirements for transferrin recycling in intact and disrupted MDCK cells, EMBO J., 9, 3477, 10.1002/j.1460-2075.1990.tb07556.x · DOI
  41. Prydz, 1992, Effects of brefeldin A on endocytosis, transcytosis and transport to the Golgi complex in polarized MDCK cells, J. Cell Biol., 119, 259, 10.1083/jcb.119.2.259 · DOI
  42. Robinson, 1992, Insulin-regulated sorting of glucose transporters in 3T3-L1 adipocytes, Am. J. Physiol., 263, E383
  43. Robinson, 1992, Recruitment of coat proteins onto Golgi membranes in intact and permeabilized cells: effects of brefeldin A and G protein activators, Cell, 69, 129, 10.1016/0092-8674(92)90124-U · DOI
  44. Rodriguez-Boulan, 1992, Polarity of epithelial and neuronal cells, Annu. Rev. Cell Biol., 8, 395, 10.1146/annurev.cb.08.110192.002143 · DOI
  45. Slot, 1991, Immuno-localization of the insulin regulatable glucose transporter in brown adipose tissue of the rat, J. Cell Biol., 113, 123, 10.1083/jcb.113.1.123 · DOI
  46. Sztul, 1985, Biogenesis of the polymeric IgA receptor in rat hepatocytes. II. Localization of its intracellular forms by cell fractionation studies, J. Cell Biol., 100, 1255, 10.1083/jcb.100.4.1255 · DOI
  47. Unkeless, 1979, Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors, J. Exp. Med., 150, 580, 10.1084/jem.150.3.580 · DOI
  48. Wan, 1992, Brefeldin A enhances receptor-mediated transcytosis of transferrin in filter-grown MDCK cells, J. Biol. Chem., 267, 13446, 10.1016/S0021-9258(18)42231-4 · DOI
  49. Wessels, 1990, Aminopeptidase N is directly sorted to the apical domain in MDCK cells, J. Cell Biol., 111, 2923, 10.1083/jcb.111.6.2923 · DOI

Cited by

Sorted by citations

See all 134

Metadata

Authors
Matter, K., Whitney, J. A., Yamamoto, E. M., & Mellman, I.
Venue
Cell
Publisher
Elsevier BV
Published
1993-09
Volume
74
Issue
6
Pages
1053-1064
ISSN
0092-8674
DOI
10.1016/0092-8674(93)90727-8
Cited by
134
References
2
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review