Cited by 1,001Olfactory and Sensory Function StudiesIon Channels and ReceptorsBiochemical Analysis and Sensing Techniques

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A novel family of genes encoding putative pheromone receptors in mammals

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Dulac, Catherine, Axel, Richard·1995·Cell

DOI 10.1016/0092-8674(95)90161-2

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Abstract

In mammals, olfactory sensory perception is mediated by two anatomically and functionally distinct sensory organs: the main olfactory epithelium (MOE) and the vomeronasal organ (VNO). Pheromones activate the VNO and elicit a characteristic array of innate reproductive and social behaviors, along with dramatic neuroendocrine responses. Differential screening of cDNA libraries constructed from single sensory neurons from the rat VNO has led to the isolation of a family of about 30 putative receptor genes. Sequence analysis indicates that these genes comprise a novel family of seven transmembrane domain proteins unrelated to the receptors expressed in the MOE. Moreover, the expression of each member of the gene family is restricted to a small subpopulation of VNO neurons. These genes are likely to encode mammalian pheromone receptors.

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Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
Buck, L., & Axel, R. (1991) · Cell · doi:10.1016/0092-8674(91)90418-x · Cited by 4,987
Self-citation
Amygdaloid projections to subcortical structures within the basal forebrain and brainstem in the rat and cat
Krettek, J. E., & Price, J. L. (1978) · Journal of Comparative Neurology · doi:10.1002/cne.901780204 · Cited by 1,293
Topographic organization of sensory projections to the olfactory bulb
Vassar, R. J., Chao, S. K., Sitcheran, R., ̃ez, J. M. N., Vosshall, L. B., & Axel, R. (1994) · Cell · doi:10.1016/0092-8674(94)90029-9 · Cited by 1,281
Self-citation
Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb
Ressler, K. J., Sullivan, S. L., & Buck, L. B. (1994) · Cell · doi:10.1016/0092-8674(94)90015-9 · Cited by 1,202
A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes
Schaeren‐Wiemers, N., & Gerfin-Moser, A. (1993) · Histochemistry and Cell Biology · doi:10.1007/bf00267823 · Cited by 1,151
STRUCTURE AND FUNCTION OF G PROTEIN-COUPLED RECEPTORS
Strader, C. D., Fong, T. M., Tota, M. R., Underwood, D. J., & Dixon, R. A. F. (1994) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.63.070194.000533 · Cited by 1,080
Allelic inactivation regulates olfactory receptor gene expression
Chess, A. J., Simon, I., Cedar, H., & Axel, R. (1994) · Cell · doi:10.1016/s0092-8674(94)90562-2 · Cited by 1,066
Self-citation
A zonal organization of odorant receptor gene expression in the olfactory epithelium
Ressler, K. J., Sullivan, S. L., & Buck, L. B. (1993) · Cell · doi:10.1016/0092-8674(93)90145-g · Cited by 1,054
The differential projections of the olfactory bulb and accessory olfactory bulb in mammals
Scalia, F., & Winans, S. S. (1975) · The Journal of Comparative Neurology · doi:10.1002/cne.901610105 · Cited by 978

Show all 62 references

Research works printed but not linked: 2

Jacobson, 1811, Description anatomique d'un organe observe dans les mammiferes, Ann. Mus. Hist. Natl. (Paris), 18, 412
Potiquet, 1891, Le canal de Jacobson, Rev. Laryng., 2, 737

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Microarrays and the Gene Expression Profile of a Single Cell
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Cladistic Analysis of Olfactory and Vomeronasal Systems
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Spatially Restricted Expression of Regulators of G-Protein Signaling in Primary Olfactory Neurons
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Authors: Dulac, C., & Axel, R.
Affiliations: Columbia University (US)
Howard Hughes Medical Institute (US)
ORCID: Dulac, Catherine
Axel, Richard
Venue: Cell
Publisher: Elsevier BV
Published: 1995-10
Volume: 83
Issue: 2
Pages: 195-206
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/0092-8674(95)90161-2
OpenAlex: W2020791858
Cited by: 1,001
References: 62
Citations by year: 2026: 7 · 2025: 16 · 2024: 27 · 2023: 20 · 2022: 18 · 2021: 25 · 2020: 19 · 2019: 31 · 2018: 19 · 2017: 17 · 2016: 30 · 2015: 24 · 2014: 33 · 2013: 30 · 2012: 31
FWCI: 19.89
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor, 3118 d)
Locations: Cell (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
Funders: Howard Hughes Medical Institute
National Institutes of Health (5p01ns029832-10)
National Institute of Neurological Disorders and Stroke (NS 29832-04)
Topics: Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
Life Sciences › Neuroscience › Sensory Systems › Ion Channels and Receptors
Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
Keywords: pheromone receptors, vomeronasal organ, vomeronasal sensory neurons, seven-transmembrane proteins, olfactory sensory neurons, gene family, cDNA cloning, rats, social behavior, reproductive behavior, neuroendocrine response
MeSH terms: Amino Acid Sequence, Animals, Base Sequence, Multigene Family, Membrane Proteins, Molecular Sequence Data, Nasal Septum, Nose, Pheromones, Smell, Blotting, Southern, Gene Library, Sequence Homology, Amino Acid, In Situ Hybridization, Sequence Analysis, DNA, Olfactory Receptor Neurons, DNA, Complementary, Rats

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A novel family of genes encoding putative pheromone receptors in mammals

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