Cited by 437Circadian rhythm and melatoninSleep and Work-Related FatigueSleep and related disorders

The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.

Association of sleep-wake habits in older people with changes in output of circadian pacemaker

Czeisler, C.A, Dumont, M, Duffy, J.F, Steinberg, J.D, Richardson, G.S, Brown, E.N, Sánchez, R, Ríos, C.D, Ronda, J.M·1992·The Lancet

DOI 10.1016/0140-6736(92)92817-y

Open this paper in CoChat — free account

Abstract

Many elderly people complain of disturbed sleep patterns but there is not evidence that the need to sleep decreases with age; it seems rather that the timing and consolidation of sleep change. We tried to find out whether there is a concurrent change in the output of the circadian pacemaker with age. The phase and amplitude of the pacemaker's output were assessed by continuous measurement of the core body temperature during 40 h of sustained wakefulness under constant behavioural and environmental conditions. 27 young men (18-31 years) were compared with 21 older people (65-85 years; 11 men, 10 women); all were healthy and without sleep complaints. The mean amplitude of the endogenous circadian temperature oscillation (ECA) was 40% greater in young men than in the older group. Older men had a lower mean temperature ECA than older women. The minimum of the endogenous phase of the circadian temperature oscillation (ECP) occurred 1 h 52 min earlier in the older than in the young group. Customary bedtimes and waketimes were also earlier in the older group, as was their daily alertness peak. There was a close correlation between habitual waketime and temperature ECP in young men, which may lose precision with age, especially among women. These findings provide evidence for systematic age-related changes in the output of the human circadian pacemaker. We suggest that these changes may underlie the common complaints of sleep disturbance among elderly people. These changes could reflect the observed age-related deterioration of the hypothalamic nuclei that drive mammalian circadian rhythms.

Integrity signals

Registry

Crossref · 10.1016/0140-6736(92)92817-y

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

A self-assessment questionnaire to determine morningness- eveningness in human circadian rhythms
Home, J. K. (1976) · Medical Entomology and Zoology · Cited by 4,783
Untitled work
(1976) · PubMed · Cited by 3,979
Bright Light Induction of Strong (Type 0) Resetting of the Human Circadian Pacemaker
Czeisler, C. A., Kronauer, R. E., Allan, J. S., Duffy, J. F., Jewett, M. E., Brown, E. N., & Ronda, J. M. (1989) · Science · doi:10.1126/science.2734611 · Cited by 946
Self-citation
Human Sleep: Its Duration and Organization Depend on Its Circadian Phase
Czeisler, C. A., Weitzman, E. D., Moore-Ede, M. C., Zimmerman, J. C., & Knauer, R. S. (1980) · Science · doi:10.1126/science.7434029 · Cited by 903
Self-citation
The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
Swaab, D. F., Fliers, E., & Partiman, T. S. (1985) · Brain Research · doi:10.1016/0006-8993(85)91350-2 · Cited by 847
Bright light resets the human circadian pacemaker independent of the timing of the sleep-wake cycle
Czeisler, C. A., Allan, J. S., Strogatz, S. H., Ronda, J. M., Sánchez, R., Ríos, C. D., Freitag, W. O., Richardson, G. S., & Kronauer, R. E. (1986) · Science · doi:10.1126/science.3726555 · Cited by 770
Self-citation
Exposure to Bright Light and Darkness to Treat Physiologic Maladaptation to Night Work
Czeisler, C. A., Johnson, M. P., Duffy, J. F., Brown, E. N., Ronda, J. M., & Kronauer, R. E. (1990) · New England Journal of Medicine · doi:10.1056/nejm199005033221801 · Cited by 580
Self-citation
The circadian system of man—Results of experiments under temporal isolation
(1980) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/s0300-9629(80)80040-5 · Cited by 515
Chronobiology of aging: Temperature, sleep-wake rhythms and entrainment
Weitzman, E. D., Moline, M. L., Czeisler, C. A., & Zimmerman, J. C. (1982) · Neurobiology of Aging · doi:10.1016/0197-4580(82)90018-5 · Cited by 367
Self-citation
Presenile Dementia
Coblentz, J. M. (1973) · Archives of Neurology · doi:10.1001/archneur.1973.00490290039003 · Cited by 317

Show all 25 references

Research works printed but not linked: 2

Dumont, 1990, Endogenous circadian phase and amplitude in elderly patients with a complaint of insomnia, Sleep Res, 19, 217
Campbell, 1991, Bright light treatment of sleep disturbance in older subjects, Sleep Res, 20, 448

Sorted by citations

Items 301–400 of 436

The complexity and commonness of the two-process model of sleep regulation from a mathematical perspective
Skeldon, A. C., & Dijk, D. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-025-00039-z · Cited by 10
Bifurcations of Sleep Patterns due to Homeostatic and Circadian Variation in a Sleep-Wake Flip-Flop Model
Athanasouli, C., Piltz, S. H., Behn, C. D., & Booth, V. (2022) · SIAM Journal on Applied Dynamical Systems · doi:10.1137/21m1446149 · Cited by 10
Objectively measured habitual physical activity and sleep-related phenomena in 1645 people aged 1–91 years: The Nakanojo Community Study
Aoyagi, Y., Park, S. J., Cho, S., & Shephard, R. J. (2018) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2018.06.013 · Cited by 10
Circadian Rhythms in Older Adults
Tranah, G. J., Stone, K. L., & Ancoli‐Israel, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-323-24288-2.00154-9 · Cited by 10
Preventive Effects of Ramelteon, Suvorexant, and Lemborexant on Delirium in Hospitalized Patients With Physical Disease
Henmi, R., Nakamura, T., Mashimoto, M., Takase, F., & Ozone, M. (2024) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001876 · Cited by 9
Timing, Duration and Quality of Sleep, and Level of Daytime Sleepiness in 1166 Retired Seniors
Monk, T. H., Buysse, D. J., Schlarb, J. E., & Beach, S. R. (2012) · Healthy Aging & Clinical Care in the Elderly · doi:10.4137/hacce.s10596 · Cited by 9
Age-related changes in neurochemical components and retinal projections of rat intergeniculate leaflet
Fiuza, F. P., Silva, K. D. A., Pessoa, R. A., de Pontes, A. L. B., Cavalcanti, R. L. P., Pires, R. S., Soares, J. G., do Nascimento, E. S., Costa, M. S. M. O., Engelberth, R. C. G. J., et al. (2015) · AGE · doi:10.1007/s11357-015-9867-9 · Cited by 9
Sleep quality in older adults: effects of exercise training and influence of sunlight exposure
O’Connor, P. J. (1997) · JAMA · doi:10.1001/jama.277.13.1034 · Cited by 9
Promoting health and survival through lowered body temperature
Conti, B., & de Cabo, R. (2025) · Nature Aging · doi:10.1038/s43587-025-00850-0 · Cited by 8
Volitional lifestyle and nocturnal sleep in the healthy elderly
Shirota, A., Tamaki, M., Nittono, H., Hayashi, M., & Hori, T. (2001) · Cited by 8
Circadian Rhythm of Distal Skin Temperature in Healthy Older and Young Women and Its Relationship with Sleep–Wake Rhythm and Environmental Factors under Natural Living Conditions
Dittmar, M., Stark, T., & Wedell, S. (2024) · Geriatrics · doi:10.3390/geriatrics9040102 · Cited by 7
Attenuated melanopsin-mediated post-illumination pupillary response is associated with reduced actigraphic amplitude and mesor in older adults
Chan, J. W. Y., Li, C.-T., Chau, S. W. H., Chan, N. Y., Li, T. M. H., Huang, B., Tsoh, J., Li, S. X., Chong, K. K. L., Roecklein, K. A., et al. (2024) · SLEEP · doi:10.1093/sleep/zsae239 · Cited by 8
The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
Huang, P., Wu, J., Liu, T., Tsai, Y., Chen, P.-T., Liao, C., & Toh, H. S. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1171294 · Cited by 7
Relationship between Sleep and Quality of Life in Elderly Community Residents
SHIRAIWA, K., MURATA, S., 堀江, 淳., Hiroshi, O. T. A. O., Murata, J., & 純弥, 宮. (2013) · Japanese Journal of Health Promotion and Physical Therapy · doi:10.9759/hppt.3.103 · Cited by 7
Observations of age-related differences in neurobehavioral performance in a 12-hour shift system
Kandelaars, K. J., Baulk, S. D., Fletcher, A., Eitzen, G. E., Roach, G. D., & Dawson, D. E. (2006) · Sleep and Biological Rhythms · doi:10.1111/j.1479-8425.2006.00196.x · Cited by 7
Sleep Management Promotes Healthy Lifestyle, Mental Health, QOL, and a Healthy Brain
Tanaka, H., & Furutani, M. (2012) · Advances in bioinformatics and biomedical engineering book series · doi:10.4018/978-1-4666-2113-8.ch022 · Cited by 7
Les facteurs d’accidents de la route par somnolence chez les conducteurs âgésPrévention par l’activité physiqueSleepiness-related road traffic accidents among elderly drivers: an analysis of the contributory factorsThe preventive role of physical activity
Gruau, S., Pottier, A., Davenne, D., & Denise, P. (2003) · Recherche Transports Sécurité · doi:10.1016/s0761-8980(03)00011-6 · Cited by 7
Sleep disorders in neurodegenerative diseases other than Parkinson's disease
Auger, R. R., & Boeve, B. F. (2010) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52007-4.00020-5 · Cited by 7
The forbidden zone for sleep is more robust in adolescents compared to adults
Monterastelli, A. J., Adams, J. E., Eastman, C. I., & Crowley, S. J. (2024) · Frontiers in Sleep · doi:10.3389/frsle.2023.1304647 · Cited by 6
A review of symptom, pathogenesis and treatment characteristics of the elderly with chronic insomnia
Xia, L., Liu, H., & Ren, J. (2025) · Medicine · doi:10.1097/md.0000000000041346 · Cited by 6
The Biological Clock and Sleep in the Elderly
Juda, M., Münch, M. Y., Wirz‐Justice, A., Merrow, M. W., & Roenneberg, T. (2006) · Zeitschrift für Gerontopsychologie & -psychiatrie · doi:10.1024/1011-6877.19.1.45 · Cited by 6
Sleep and Temperature
Kim, H.-G., & Seo, W. S. (2016) · Sleep Medicine and Psychophysiology · doi:10.14401/kasmed.2016.23.2.47 · Cited by 6
Multi-day Longitudinal Assessment of Physical Activity and Sleep Behavior Among Healthy Young and Older Adults Using Wearable Sensors
Soangra, R. (2019) · IRBM · doi:10.1016/j.irbm.2019.10.002 · Cited by 6
Sleep associated endocrine and immune changes in the elderly
Perras, B., & Jan Born, A. (2005) · Advances in cell aging and gerontology · doi:10.1016/s1566-3124(04)17005-3 · Cited by 6
Daily rhythms of native Brazilians in summer and winter
Wey, D., Böhn, A., & Menna-Barreto, L. S. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.10.006 · Cited by 6
Effects of Activity of Daily Living and Gender on Circadian Rhythms of the Elderly in a Nursing Home.
Okamoto-Mizuno, K., Yokoya, T., & Kudoh, Y. (2000) · Journal of PHYSIOLOGICAL ANTHROPOLOGY and Applied Human Science · doi:10.2114/jpa.19.53 · Cited by 6
Sleep Disturbances in Late Life
Morin, C. M., Blais, F. C., & Mimeault, V. (1998) · Springer eBooks · doi:10.1007/978-1-4899-0130-9_13 · Cited by 6
The circadian rhythm of human body temperature – Clinical implications and review of the literature
Geneva, I. I. (2025) · Chronobiology International · doi:10.1080/07420528.2025.2511268 · Cited by 5
Spatiotemporal light exposure modeling for environmental circadian misalignment and solar jetlag
VoPham, T., Ton, M., & Weaver, M. D. (2024) · Environmental Epidemiology · doi:10.1097/ee9.0000000000000301 · Cited by 5
Sleep and Aging: Endocrine and Epigenetic Aspects
Bulgakova, S. V., & Romanchuk, N. (2020) · Bulletin of Science and Practice · doi:10.33619/2414-2948/57/08 · Cited by 5
Proof of concept for the role of glycemic control in the early detection of infections in diabetics
Botsis, T., Lai, A. M., Palmas, W., Starren, J. B., Hartvigsen, G., & Hripcsak, G. M. (2012) · Health Informatics Journal · doi:10.1177/1460458211428427 · Cited by 5
Circadian Rhythm Alterations with Aging
Naylor, E., & Zee, P. C. (2006) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2006.04.006 · Cited by 5
Circadian Rhythms during Aging
Gore, A. C. (1998) · KARGER eBooks · doi:10.1159/000061417 · Cited by 5
Why do circadian biorhythms age?
Berger, J. (2003) · Journal of Applied Biomedicine · doi:10.32725/jab.2003.012 · Cited by 5
Long-Term Study of Physical, Haematological, and Biochemical Parameters in Cattle with Different Embryo Origins
Albal, M. S., Romero‐Aguirregomezcorta, J., Cánovas, S., Heras, S., Gadea, J., Coy, P., & Romar, R. (2025) · Animals · doi:10.3390/ani15121763 · Cited by 4
Sleep–wake modulation and pathogenesis of Alzheimer disease: Suggestions for postponement and treatment
Liu, Y.-J., Swaab, D. F., & Zhou, J.-N. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-323-90918-1.00001-0 · Cited by 4
Comparative Study of Circadian Oscillatory Network Models of Drosophila
Ogawa, Y., Arakawa, K., Kaizu, K., Miyoshi, F., Nakayama, Y., & Tomita, M. (2008) · Artificial Life · doi:10.1162/artl.2008.14.1.29 · Cited by 4
Premature Coronary Artery Disease Is More Prevalent in People Who Go to Bed Late
Masoudkabir, F., Mohammadi, Z., Alirezaei, M., Cheraghian, B., Rahimi, Z., Roayaei, P., Naderian, M. R., Danehchin, L., Paridar, Y., Abolnezhadian, F., et al. (2021) · Archives of Iranian Medicine · doi:10.34172/aim.2021.131 · Cited by 4
Association Between Mild Cognitive Impairment and Seasonal Rest-Activity Patterns of Older Adults
Reynolds, C. L., Mattek, N., Lim, M. M., Beattie, Z., Dodge, H. H., & Kaye, J. A. (2022) · Frontiers in Digital Health · doi:10.3389/fdgth.2022.809370 · Cited by 4
Insomnia in the Elderly
Gehrman, P., & Ancoli‐Israel, S. (2010) · Medical psychiatry · doi:10.3109/9781420080803.020 · Cited by 4
Sunlight levels and behavioural disturbance in dementia
Sheehan, B., & Keene, J. (2002) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.690 · Cited by 4
Circadian regulation of sleep propensity, sleep structure and alertness: A symphony of paradoxes
Dijk, D. (1995) · Acta Neuropsychiatrica · doi:10.1017/s0924270800037467 · Cited by 4
The Circadian Clock and the Homeostatic Hourglass: Two Timepieces Controlling Sleep and Wakefulness
Chellappa, S. L., & Cajochen, C. (2009) · Springer eBooks · doi:10.1007/978-1-4419-1262-6_9 · Cited by 5
Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases
Lyashenko, E. A., Poluektov, M. G., Levin, O. S., & Pchelina, P. V. (2015) · Current Aging Science · doi:10.2174/1874609809666151130220219 · Cited by 3
Relationship between chronobiology and aging: adjustments facing the technological world
Federal University of Paraná, Pinto, L. S. D. C., Vincenzi, R. A., Federal University of Paraná, Schaedler, T., Federal University of Paraná, Perrut, G., Federal University of Paraná, Louzada, F. M., & Federal University of Paraná (2017) · Geriatrics Gerontology and Aging · doi:10.5327/z2447-211520162016029 · Cited by 3
Effect of a home-based videoconferencing exercise training program on circadian rhythms and sleep quality in healthy older adults
Milot, E., Langeard, A., Rehel, S., Bigot, L., Gauthier, A., Bessot, N., & Quarck, G. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106746 · Cited by 3
Sleep: Approaching the Fundamental Questions
Baumann, C. R. (2008) · Current Biology · doi:10.1016/j.cub.2008.06.022 · Cited by 3
Circadian clock speed increases during aging in the male Syrian hamster: A large-scale study
Gannon, R. L. (2015) · Chronobiology International · doi:10.3109/07420528.2015.1064938 · Cited by 3
Effect of Yokukansan, a Traditional Herbal Prescription, on Sle ep Disturbances in Patients with Alzheimer's Disease
Shinno, H., & Ishikawa, I. (2016) · Journal of Alzheimer’s Disease & Parkinsonism · doi:10.4172/2161-0460.1000215 · Cited by 3
CHANGES OF SLEEP OR WAKING HABITS BY AGE AND SEX IN JAPANESE
Park, Y. M. (2002) · Perceptual and Motor Skills · doi:10.2466/pms.94.2.1199-1213 · Cited by 3
CHANGES OF SLEEP OR WAKING HABITS BY AGE AND SEX IN JAPANESE
Park, Y. M. (2002) · Perceptual and Motor Skills · doi:10.2466/pms.94.3.1199-1213 · Cited by 3
Nocturnal sleep latencies among alert, alert-deprived and sleepy subjects
Helmus, T. C., Rosenthal, L. D., Bishop, C., Roehrs, T., Krsevska, S., & Roth, T. G. (1996) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0921-884x(96)95197-8 · Cited by 3
Diagnosis and Treatment of Insomnia
Uchiyama, M., & Ozaki, S. (1997) · Springer eBooks · doi:10.1007/978-1-4899-0245-0_8 · Cited by 3
Physiology of Sleep Homeostasis and Its Circadian Regulation
Dijk, D. (1997) · KARGER eBooks · doi:10.1159/000061562 · Cited by 3
Sleep and Hormonal Rhythms in Humans
Copinschi, G., Leproult, R., & Cauter, E. V. (2001) · Elsevier eBooks · doi:10.1016/b978-012351830-9/50062-7 · Cited by 3
DIURNAL VARIATION IN LANGUAGE TESTS AND RELEVANCE TO EARLY DETECTION OF DEMENTIA: DISRUPTION OF TIME DEPENDENCY IN DEMENTING SUBJECTS
Arzi, A. Y. T., & Ashkenazi, I. E. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb03756.x · Cited by 3
EFFECTS OF AGING AND INFLAMMATORY MOLECULES ON THE SUPRACHIASMATIC CIRCADIAN CLOCK
Nygård, M. (2007) · Figshare · Cited by 3
Circadian rhythms and aging
Waterhouse, J. M., & Minors, D. S. (1996) · Reviews in Clinical Gerontology · doi:10.1017/s0959259800004457 · Cited by 3
The health cost of irregular sleep timing: age differences in social jet lag and health outcomes among middle-aged and older adults
Tracy, E. L., Kim, E., Meinertz, N., & Nyang'Au, G. (2025) · The Journals of Gerontology Series A · doi:10.1093/gerona/glaf216 · Cited by 2
Circadian Regulation of Neuronal Membrane Capacitance—Mechanisms and Implications for Neural Computation and Behavior
Nowacka, A., Śniegocki, M., Bożiłow, D., & Ziółkowska, E. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110766 · Cited by 2
Circadian rest-activity rhythms and physical function in community-dwelling older men: The MrOS sleep study
Qiao, Y., Blackwell, T., Chen, D. M., Zeitzer, J. M., Ancoli‐Israel, S., Posner, A. B., Redline, S. S., Tranah, G. J., Yaffe, K. S., & Stone, K. L. (2025) · Sleep Health · doi:10.1016/j.sleh.2025.10.005 · Cited by 3
Assessment and treatment of insomnia (including a case control study of patients with Primary Insomnia)
Sharpley, A. L., Attenburrow, M. E. J., & Cowen, P. J. (1997) · International Journal of Psychiatry in Clinical Practice · doi:10.3109/13651509709024712 · Cited by 2
Sleep Needs a MOP, or Two MOPs!
Partonen, T. (2013) · SLEEP · doi:10.5665/sleep.2438 · Cited by 2
Assessment of sleep quality in severe covid-19 hospitalized patients
Abbasi, N. Z., Baig, K., Hassan, M., Syed, F., Jami, M. A. W., & Usman, M. (2024) · Journal of the Pakistan Medical Association · doi:10.47391/jpma.7704 · Cited by 2
Devenir des rythmes avec l’âge
Benoît, M. (2006) · L Encéphale · doi:10.1016/s0013-7006(06)76241-8 · Cited by 2
Relationships between Age, Morning-Type and Rigidity Sleeping Habits with Shiftwork Tolerance
Pordanjani, T. R., Ali, M. E., & Kazem, N. (2013) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2
Sleep Among Older Adults
Stone, K. L., & Li, V. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780190930448.003.0006 · Cited by 2
Insomnia
Yang, C., Spielman, A. J., & Huang, Y. (2005) · Current Treatment Options in Neurology · doi:10.1007/s11940-005-0030-2 · Cited by 2
Reversing Disability in Old Age
Levy, B. R., & Langer, E. J. (2007) · Springer eBooks · doi:10.1007/978-0-585-27572-7_8 · Cited by 2
Shift Work: An Occupational Health and Safety Hazard
Buxton, S. M. (2003) · Murdoch University Research Portal · Cited by 2
Melatonin deficiency and its implications for the treatment of insomnia in elderly subjects
Laudon, M., & Zisapel, N. (1998) · The Aging Male · doi:10.3109/13685539809148437 · Cited by 2
Sleepiness in advanced and delayed sleep phase disorders
Campbell, S. S., & Murphy, P. (2011) · Cambridge University Press eBooks · doi:10.1017/cbo9780511762697.019 · Cited by 1
Vieillissement cognitif et effets de l'exercice
Bertsch, J., Lobjois, R., Maquestiaux, F., & Benguigui, N. (2005) · Bulletin de psychologie · doi:10.3917/bupsy.475.0039 · Cited by 1
Determining the relationship between sleep and social activity in community-dwelling older people
Behan, J., Pendergast, D., Quigley, B., & Walsh, L. C. (2008) · Gerontechnology · doi:10.4017/gt.2008.07.02.007.00 · Cited by 1
Circadian rhythm dysregulation in the elderly: shift work
Monk, T. H. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511770661.016 · Cited by 1
The Role of Environmental Context in Modulating Subjective Sleepiness and Sleep Quality in the Elderly: A Comparison Between Home-Dwelling Subjects and Nursing Home Residents
Conte, F., Malloggi, S., Albinni, B., Cerasuolo, M., Ficca, G., & Giganti, F. (2019) · Home Health Care Management & Practice · doi:10.1177/1084822319883824 · Cited by 1
Understanding Skin Chronobiology to Unveil and Transform Dermal Chronotherapeutics: Paving the Way for the Future
Thoke, J., Patel, S., & Majumdar, A. S. (2021) · Chronobiology in Medicine · doi:10.33069/cim.2020.0032 · Cited by 1
Sleep health and aging
Shochat, T. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-815501-1.00009-0 · Cited by 1
Investigation of the aging clock's intermittent-light responses uncovers selective deficits to green millisecond flashes
Kaladchibachi, S., Negelspach, D., Zeitzer, J. M., & Fernandez, F. (2022) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2022.112389 · Cited by 1
Melatonin
Kunz, D., & Mahlberg, R. (2006) · Springer eBooks · doi:10.1007/0-387-27682-3_9 · Cited by 1
Circadian Rhythm Disorders in Children and Adults
Velamuri, K., Singh, S., Agrawal, R., Moghtader, S., & Sharafkhaneh, A. (2023) · Springer eBooks · doi:10.1007/978-3-031-30010-3_12 · Cited by 2
Human Body Temperature Circadian Rhythm in Health and Disease
Geneva, I. I. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1003852 · Cited by 1
Studies on Sleep-wake Patterns of the Frail Elderly
Tsutsumi, M. (2008) · Yamaguchi Medical Journal · doi:10.2342/ymj.57.91 · Cited by 1
Developing Circadian Therapeutics Against Age-Related Metabolic Decline
Nohara, K., Yoo, S. H., & Chen, Z. (2017) · Healthy ageing and longevity · doi:10.1007/978-3-319-64543-8_11 · Cited by 1
Circadian Sleep-Wake Activity Patterns During Aging
Stone, K. L., & Tranah, G. J. (2017) · Healthy ageing and longevity · doi:10.1007/978-3-319-64543-8_13 · Cited by 1
Subjective sleep quality in the elderly: relationship to anxiety, depressed mood, sleep beliefs, quality of life, and hypnotic use
Galea, M. (2008) · Victoria University Research Repository (Victoria University) · Cited by 1
Sleep wakefulness cycle
Hume, K. I., Van, F., & Watson, A. (1993) · Journal of Interdisiplinary Cycle Research · doi:10.1080/09291019309360236 · Cited by 1
Sleep and Circadian Rhythms in Dementia
Harper, D. G. (2011) · Wiley eBooks · doi:10.1002/9781444344110.ch16 · Cited by 1
Social Rhythms and Nocturnal Routines in Community Dwelling Older Adults
Behan, J., Prendergast, D. K., Walsh, L. C., & Quigley, B. (2008) · Lecture notes in computer science · doi:10.1007/978-3-540-69916-3_9 · Cited by 1
How to Measure Circadian Rhythmicity in Humans
Hofstra, W. A., & de Weerd, A. (2011) · Epilepsy · doi:10.1201/b10866-45 · Cited by 1
Circadian Rhythms, Aging and Dementia
Monk, H. T., & Zee, C. P. (2001) · Handbook of behavioral neurobiology · doi:10.1007/978-1-4615-1201-1_23 · Cited by 1
Circadian rhythm sleep disorders related to an abnormal escape of the sleep-wake cycle
Boivin, D. B., & Santo, J. B. (2003) · Springer eBooks · doi:10.1007/978-1-4615-0217-3_40
The Effects of Evening Bright-Light on Human Body Temperature and Sleep Architecture
Croft, T. D. (1996) · UTAS Research Repository · doi:10.25959/23222717
要介護高齢者の興昧・関心を考慮したアクティビティケアの効果 : 音楽・運動・趣味プログラム参加による睡眠・覚醒パターンヘの影響
堤, 雅., 涌井, 忠., 小林, 敏., & 田中, マ. (2007) · 老年看護学 : 日本老年看護学会誌 : journal of Japan Academy of Gerontological Nursing · doi:10.20696/jagn.12.1_101
Cambios fisiológicos durante el sueño
Chokroverty, S. (2011) · Elsevier eBooks · doi:10.1016/b978-84-8086-733-7.00007-3
THE PUZZLE OF DECREASED HOMEOSTATIC SLOW WAVE SLEEP IN AGING
Rytkönen, K.-M. (2012) · Työväentutkimus Vuosikirja
Les troubles du sommeil et leurs répercussions chez les sujets âgés, en bonne santé, dépendants et fragiles
Cock, V. C. D., Arbus, C., Soto, M., Debs, R., Villars, H., Tiberge, M., Montemayor, T., Hein, C., Veccherini, M. F., Onen, S. ‐., et al. (2009) · Les cahiers de l année gérontologique · doi:10.1007/s12612-009-0020-1
Padrão temporal de exposição ao ciclo claro/escuro natural e expressão dos cronotipos em uma região rural.
Back, F. A. (2008) · doi:10.11606/d.42.2008.tde-15092008-124927
Quazepam Improves Health-related Quality of Life and Nocturia in Elderly Japanese Patients with Chronic Insomnia
Ohbayashi, H. (2009) · Journal of Rural Medicine · doi:10.2185/jrm.4.1
Circadian Rhythms of Activity and Rectal Temperature at Home and in a Hospital: Effects of Lifestyle
Minors, D. S., Pirmohamed, J., Williams, G., Edwards, R. H. T., Healy, D., & Waterhouse, J. M. (1995) · Chronobiology International · doi:10.3109/07420529509057266

Authors: Czeisler, C. A., Dumont, M., Duffy, J. F., Steinberg, J. D., Richardson, G. S., Brown, E. N., Sánchez, R., Ríos, C. D., & Ronda, J. M.
Affiliations: Brigham and Women's Hospital (US)
Corresponding author: Czeisler, C.A
ORCID: Czeisler, C.A
Dumont, M
Duffy, J.F
Brown, E.N
Ronda, J.M
Venue: The Lancet
Publisher: Elsevier BV
Published: 1992-10
Volume: 340
Issue: 8825
Pages: 933-936
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/0140-6736(92)92817-y
OpenAlex: W2052495561
Cited by: 437
References: 25
Citations by year: 2026: 3 · 2025: 17 · 2024: 9 · 2023: 13 · 2022: 12 · 2021: 13 · 2020: 8 · 2019: 10 · 2018: 12 · 2017: 16 · 2016: 11 · 2015: 10 · 2014: 9 · 2013: 11 · 2012: 9
FWCI: 8.02
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (R01AG006072, 1-RO1-AG06072, 1-P01-AG-09975, P01AG009975)
National Institute of Mental Health (H5-ROI-MH45130)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Keywords: circadian pacemaker, aging, core body temperature, circadian rhythm, alertness, hypothalamic nuclei, sex differences
MeSH terms: Adult, Aged, Aged, 80 and over, Aging, Body Temperature, Circadian Rhythm, Female, Humans, Male, Sex Factors, Sleep Deprivation, Time Factors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Association of sleep-wake habits in older people with changes in output of circadian pacemaker

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks