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Lipid composition and metabolism in normal and diseased epidermis
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“The main constituents of lipid lamellae are ceramides, cholesterol, and FFAs, of which ceramides account for 50% by weight (4).”
From Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC/MS/MS (2020) · cites this paper as [4]
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Essential Fatty Acids And Polyunsaturated Fatty Acids: Significance In Cutaneous Biology
Ziboh, V. A., & Miller, C. C. (1990) · Annual Review of Nutrition · doi:10.1146/annurev.nu.10.070190.002245 · Cited by 49
A hypothesis on the cause of chronic epidermal hyperproliferation in asebia mice
Brown, W. R., & Hardy, M. H. (1988) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.1988.tb00661.x · Cited by 49
Metadata
- Authors
- Yardley, H. J., & Summerly, R.
- Affiliations
- Keele University (GB)
- Royal Stoke University Hospital (GB)
- Venue
- Pharmacology & Therapeutics
- Publisher
- Elsevier BV
- Published
- 1981-01
- Volume
- 13
- Issue
- 2
- Pages
- 357-383
- ISSN
- 0163-7258 (ISSN-L)
- OpenAlex
- W2005090658
- Cited by
- 267
- References
- 209
- Citations by year
- 2026: 1 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 2 · 2021: 8 · 2020: 2 · 2019: 1 · 2017: 4 · 2016: 2 · 2015: 2 · 2014: 1 · 2013: 11 · 2012: 4
- FWCI
- 4.14
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Pharmacology & Therapeutics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- epidermis, skin lipids, lipid metabolism, lipid composition, skin diseases, stratum corneum
- MeSH terms
- Fatty Acids, Fatty Acids, Essential, Humans, Hydrocarbons, Ichthyosis, Keratins, Lipids, Phospholipids, Psoriasis, Skin, Skin Diseases, Skin Physiological Phenomena, Sphingolipids, Sterols, Subcellular Fractions, Waxes, Lipid Metabolism
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