Somatic and psychological symptoms during isoproterenol-induced panic attacks
Abstract
To determine which symptoms characterized isoproterenol-induced panic attacks, we analyzed the presence of panic attacks in 54 panic disorder patients who panicked, 24 patients who did not panic, and 37 controls who did not panic during isoproterenol infusions. The increases over the baseline of the symptoms shortness of breath and fear of going crazy were highly associated with panicking patients when compared to nonpanicking patients and nonpanicking controls. The increases of the symptoms trembling and shaking, generally nervous, and fear of going crazy were highly associated with patients when compared to controls. The possibility of a cognitive theory of panic attacks is discussed.
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Older evidence shows that isoproterenol can trigger panic and anxiety in experimental settings.
“older evidence that isoproterenol can provoke panic and anxiety in experimental settings (Rainey et al., 1984; Balon et al., 1990; Pohl et al., 1988; Pohl et al., 1990).”
From Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome (2018) · cites this paper as Balon et al., 1990
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- Authors
- Balon, R., Yeragani, V. K., Pohl, R., Muench, J., & Berchou, R.
- Affiliations
- Wayne State University (US)
- Corresponding author
- Balon, Richard
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 1990-05
- Volume
- 32
- Issue
- 2
- Pages
- 103-112
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W2165371993
- Cited by
- 16
- References
- 10
- Citations by year
- 2026: 1 · 2018: 1 · 2017: 2 · 2016: 2 · 2015: 2 · 2014: 1
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Keywords
- panic attacks, panic disorder, isoproterenol challenge, somatic symptoms, psychological symptoms, dyspnea, fear of losing control, trembling, autonomic arousal
- MeSH terms
- Adolescent, Adult, Anxiety Disorders, Arousal, Double-Blind Method, Fear, Female, Humans, Infusions, Intravenous, Isoproterenol, Lactates, Male, Middle Aged, Panic, Personality Tests, Somatoform Disorders, Randomized Controlled Trials as Topic, Lactic Acid
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