The β-Receptor: Isoproterenol Anxiety States
Abstract
To learn the effect of isoproterenol on patients meeting Research Diagnostic Criteria (RDC) for panic disorder, we administered isoproterenol, racemic sodium lactate, and glucose to them and to nonpsychiatric control subjects. Each subject received all 3 infusions, double-blind in random order. A 21-item self-rating panic scale was constructed from the RDC for panic disorder and was used to identify RDC panic attacks. The results of this study and the preliminary results from the infusions after treatment with imipramine are discussed in the text, and the results from the first patient to be reinfused after treatment are presented graphically.
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Older evidence shows that isoproterenol can trigger panic and anxiety in experimental settings.
“older evidence that isoproterenol can provoke panic and anxiety in experimental settings (Rainey et al., 1984; Balon et al., 1990; Pohl et al., 1988; Pohl et al., 1990).”
From Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome (2018) · cites this paper as Rainey et al., 1984
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- Authors
- Rainey, Jr., Ettedgui, E., Pohl, B., Balon, R., Weinberg, P., Yelonek, S., & Berchou, R.
- Affiliations
- Wayne State University (US)
- ORCID
- Balon, R.
- Venue
- Psychopathology
- Publisher
- S. Karger AG
- Published
- 2010-02-05
- Volume
- 17 Suppl 3
- Pages
- 40-51
- ISSN
- 0254-4962 (ISSN-L)
- 1423-033X
- OpenAlex
- W1993792509
- Cited by
- 33
- References
- 0
- Citations by year
- 2018: 1
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychopathology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- isoproterenol, beta-adrenergic receptors, panic disorder, panic attacks, Research Diagnostic Criteria, imipramine, sodium lactate, glucose
- MeSH terms
- Adolescent, Adult, Anxiety, Female, Glucose, Humans, Imipramine, Isoproterenol, Lactates, Male, Middle Aged, Receptors, Adrenergic, beta
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