The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Motor/vocal tics and compulsive behaviors on stimulant drugs: Is there a common vulnerability?
Abstract
The occurrence of abnormal movements or perserverative/compulsive behaviors was noted in 34 (76%) of a group of 45 hyperactive boys during a double-blind crossover treatment trial of methylphenidate and dextroamphetamine given in a wide range of doses. These adverse effects were often subtle and transient, and they usually occurred only on one drug. There was only one case where treatment was discontinued due to the severity of the tic the subject developed during his initial treatment phase. Dextroamphetamine tended to produce more compulsive behaviors, which were also more likely to resemble clinical obsessive-compulsive disorder (OCD), than did methylphenidate. Abnormal movements and compulsive behaviors tended to co-occur on methylphenidate only; no general "Tourette-OCD diathesis" was found for this population.
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“dopamine agonists acting on the basal ganglia can generate OCD‐like behaviors in both animals (Szechtman et al., 1998), and humans (Borcherding et al., 1990)”
From Obsessive-compulsive disorder: Etiology, neuropathology, and cognitive dysfunction (2023) · cites this paper as Borcherding et al., 1990
Citations
Cites
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Obsessive-Compulsive Disorder in Children and Adolescents
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Gilles de la Tourette's Syndrome and Obsessive-Compulsive Disorder
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Stimulant Medications Precipitate Tourette's Syndrome
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Self-citationGilles de la Tourette's Syndrome following Methylphenidate Administration
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SPENCER, T., BIEDERMAN, J., WILENS, T., HARDING, M., O'DONNELL, D., & GRIFFIN, S. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199604000-00008 · Cited by 830
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European clinical guidelines for hyperkinetic disorder ? first upgrade
Taylor, E., D�pfner, M., Sergeant, J., Asherson, P., Banaschewski, T., Buitelaar, J., Coghill, D., Danckaerts, M., Rothenberger, A., Sonuga-Barke, E., et al. (2004) · European Child & Adolescent Psychiatry · doi:10.1007/s00787-004-1002-x · Cited by 682
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Scahill, L., Chappell, P. B., Kim, Y. S., Schultz, R. T., Katsovich, L., Shepherd, E., Arnsten, A. F. T., Cohen, D. J., & Leckman, J. F. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.7.1067 · Cited by 588
Metadata
- Authors
- Borcherding, B. G., Keysor, C. S., Rapoport, J. L., Elia, J., & Amass, J.
- Affiliations
- National Institute of Mental Health (US)
- National Institutes of Health (US)
- Corresponding author
- Rapoport, Judith L.
- ORCID
- Elia, Josephine
- Venue
- Psychiatry Research
- Publisher
- Elsevier BV
- Published
- 1990-07
- Volume
- 33
- Issue
- 1
- Pages
- 83-94
- ISSN
- 0165-1781 (ISSN-L)
- OpenAlex
- W1978755811
- Cited by
- 150
- References
- 27
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 5 · 2022: 6 · 2020: 3 · 2019: 4 · 2018: 3 · 2017: 1 · 2016: 8 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 4.19
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychiatry Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- motor tics, vocal tics, compulsive behavior, stimulant side effects, methylphenidate, d-amphetamine, hyperactive children, Tourette syndrome, obsessive-compulsive disorder, perseveration
- MeSH terms
- Attention Deficit Disorder with Hyperactivity, Child, Compulsive Behavior, Dextroamphetamine, Double-Blind Method, Tourette Syndrome, Humans, Male, Methylphenidate, Motor Activity, Neurologic Examination, Obsessive-Compulsive Disorder, Risk Factors, Stereotyped Behavior, Tic Disorders
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