Cited by 413Neuroscience of respiration and sleepSleep and Wakefulness ResearchHeart Rate Variability and Autonomic Control

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The pedunculopontine nucleus

GARCIARILL, E·1991·Progress in Neurobiology

DOI 10.1016/0301-0082(91)90016-t

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Abstract

In an effort to account for a large number of reported functions mediated by a small portion of the midbrain, a hypothesis is advanced as a basis for discussion and not as established fact and is guided by reports from a large number of laboratories working on the same region but using widely disparate preparations. Overall, the hypothesized model suggests an underlying mechanism of action for what is essentially the ascending reticular activating system. The model proposed will hopefully be tested stringently in order to arrive at a better understanding of brain stem mechanisms modulating a host of rhythmic functions.

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Authors: GARCIARILL, E.
Venue: Progress in Neurobiology
Publisher: Elsevier BV
Published: 1991
Volume: 36
Issue: 5
Pages: 363-389
ISSN: 0301-0082 (ISSN-L)
DOI: 10.1016/0301-0082(91)90016-t
OpenAlex: W1992356214
Cited by: 413
References: 259
Citations by year: 2025: 2 · 2024: 7 · 2023: 4 · 2022: 5 · 2021: 5 · 2020: 5 · 2019: 17 · 2018: 13 · 2017: 9 · 2016: 20 · 2015: 16 · 2014: 16 · 2013: 11 · 2012: 5
FWCI: 6.70
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Progress in Neurobiology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Neurological Disorders and Stroke (NS-20246, R01NS020246)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
Keywords: pedunculopontine nucleus, ascending reticular activating system, midbrain, brainstem, arousal, sleep-wake regulation
MeSH terms: Humans, Male, Mesencephalon, Periodicity, Pons

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The pedunculopontine nucleus

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