CoChat
Sign Up
Cited by 252

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey

Steriade, M., Paré, D., Parent, A., Smith, Y.·1988·Neuroscience
DOI 10.1016/0306-4522(88)90006-1
Open this paper in CoChat — free account

Abstract

The projections of brainstem core neurons to relay and associational thalamic nuclei were studied in the cat and macaque monkey by combining the retrograde transport of wheat germ agglutinin conjugated with horseradish peroxidase with choline acetyltransferase immunohistochemistry. All major sensory (medial geniculate, lateral geniculate, ventrobasal), motor (ventroanterior, ventrolateral, ventromedial), associational (mediodorsal, pulvinar, lateral posterior) and limbic (anteromedial, anteroventral) thalamic nuclei of the cat were found to receive projections from cholinergic neurons located in the peribrachial area of the pedunculopontine nucleus and in the laterodorsal tegmental nucleus as well as from non-cholinergic neurons in the rostral (perirubral) part of the central tegmental mesencephalic field. Specific relay nuclei receive less than 10% of their brainstem afferents from non-cholinergic neurons located at rostral midbrain levels and receive 85-96% of their brainstem innervation from a region at midbrain-pontine junction where the cholinergic peribrachial area and laterodorsal tegmental nucleus are maximally developed. Of the total number of horseradish peroxidase-positive brainstem neurons seen after injections in various specific relay nuclei, the double-labeled (horseradish peroxidase + choline acetyltransferase) neurons represent approximately 70-85%. Three to eight times more numerous horseradish peroxidase-labeled brainstem cells were found after injections i…

Overview

Integrity signals

Registry

Crossref · 10.1016/0306-4522(88)90006-1

Cites

3 of 3 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 3 references

Research works printed but not linked: 69

  1. Aggleton, 1983, Memory impairments following restricted medial thalamic lesions in monkeys, Expl Brain Res., 52, 199, 10.1007/BF00236628 · DOI
  2. Benevento, 1975, The ascending projections of the superior colliculus in the rhesus monkey Macaco mulatto, J. comp. Neurol., 160, 339, 10.1002/cne.901600306 · DOI
  3. Bizzi, 1963, Functional connections between pontine reticular formation and lateral geniculate nucleus during deep sleep, Archs ital. Biol., 101, 666
  4. Consolazione, 1984, Serotonin-containing projections to the thalamus in the rat revealed by a horseradish peroxidase and peroxidase antiperoxidase double-staining technique, Brain Res., 322, 233, 10.1016/0006-8993(84)90113-6 · DOI
  5. De Lima, 1987, The brainstem projection to the lateral geniculate nucleus in the cat: identification of cholinergic and monoaminergic elements, J. comp. Neurol., 259, 92, 10.1002/cne.902590107 · DOI
  6. Descheˆnes, 1986, The effect of mesencephalic reticular stimulation on relay neurons of the dorsal lateral geniculate nucleus, Soc. Neurosci. Abstr., 12, 854
  7. Edwards, 1976, Autoradiographic studies of the projections of the midbrain reticular formation: ascending projections of nucleus cuneiformis, J. comp. Neurol., 165, 417, 10.1002/cne.901650403 · DOI
  8. Filion, 1971, Neuronal discharges of the ventrolateral nucleus of the thalamus during sleep and wakefulness. II. Evoked activity, Expl Brain Res., 12, 499, 10.1007/BF00234245 · DOI
  9. Glenn, 1982, Anterogradc tracer and held potential analysis of the neocortical layer I projection from nucleus ventralis medialis of the thalamus in cat, Neuroscience, 7, 1861, 10.1016/0306-4522(82)90003-3 · DOI
  10. Graybiel, 1977, Direct and indirect preoculomotor pathways of the brainstem: an autoradiographic study of the pontine reticular formation in the cat, J. comp. Neurol., 175, 37, 10.1002/cne.901750105 · DOI
  11. Graybiel, 1980, Histochemical identification and afferent connections of subdivisions in the lateralis posterior pulvinar complex and related thalamic nuclei in the cat, Neuroscience, 5, 1175, 10.1016/0306-4522(80)90196-7 · DOI
  12. Hsu, 1981, Use of avidin biotin peroxidase complex (ABC) in immunoperoxidase technique. A comparison between ABC and unlabeled (PAP) procedure, J. Histochem. Cytochem., 29, 577, 10.1177/29.4.6166661 · DOI
  13. Hu, 1986, The effect of mesencephalic reticular stimulation on thalamic reticularis neurons, Soc. Neurosci. Abstr., 12, 854
  14. Isseroff, 1982, Spatial memory impairments following damage to the medio-dorsal nucleus of the thalamus in rhesus monkeys, Brain Res., 232, 97, 10.1016/0006-8993(82)90613-8 · DOI
  15. Jeannerod, 1970, Occipital and geniculate potentials related to eve movements in the unanesthetized cat, Brain Res., 19, 361, 10.1016/0006-8993(70)90380-X · DOI
  16. Jones, 1987, Retrograde labeling of neurons in the brain stem following injections of[3H]choline into tlie forebrain of the rat, Expl Brain Res., 65, 437, 10.1007/BF00236317 · DOI
  17. Jones, 1987, Distribution of acetylcholinc and catecholamine neurons in the cat brain stem studied by choline acetyltransferasc and tyrosine hydroxylase immunohistochemislry, J. comp. Neurol., 261, 15, 10.1002/cne.902610103 · DOI
  18. Kimura, 1981, The central cholinergic system studied by choline acetyllransferase immunohistochemistry in the cat, J. comp. Neurol., 200, 151, 10.1002/cne.902000202 · DOI
  19. Krettek, 1977, The cortical projections of the mediodorsal nucleus and adjacent thalamc nuclei in the rat, J. comp. Neurol., 171, 157, 10.1002/cne.901710204 · DOI
  20. Lavail, 1973, A method based on retrograde intra-axonal transport of protein lor identification of cell bodies of origin of axons terminating in the CNS, Brain Res., 58, 470, 10.1016/0006-8993(73)90016-4 · DOI
  21. Le Gros Clark, 1933, On the connections of the medial cell groups of the thalamus, Brain, 56, 83, 10.1093/brain/56.1.83 · DOI
  22. Levey, 1987, Choline acetyltransferase-immunoreactivity in the rat thalamus, J. comp. Neurol., 257, 317, 10.1002/cne.902570302 · DOI
  23. Levey, 1983, o-localization of acelylcholinesterase and choline acetyllransferase in the rat cerebrum, Neuroscience, 9, 9, 10.1016/0306-4522(83)90042-8 · DOI
  24. MacLeod, 1984, Regulation of cerebello-cortical transmission in the rat venlromedial thalamic nucleus, Expl Brain Res., 55, 535, 10.1007/BF00235285 · DOI
  25. Marshall, 1972, The synaptic activation of neurones of the feline venlrolateral thalamic nucleus, possible eholinergic mechanism, Expl Brain Res., 15, 472, 10.1007/BF00236403 · DOI
  26. Mesulam, 1986, Brain Res., 367, 301, 10.1016/0006-8993(86)91607-0 · DOI
  27. Mesulam, 1983, Central cholinergic pathways in the rat an overview based on an alternative nomenclature (Ch1 Ch6), Neurscience, 10, 1185, 10.1016/0306-4522(83)90108-2 · DOI
  28. Minciacchi, 1986, Multiple conical targels of one thalamic nucleus; the projections of the ventral medial nucleus in the cat studied with retrograde tracers, J. comp. Neurol., 252, 106, 10.1002/cne.902520107 · DOI
  29. Moon-Edley, 1983, The afferent and efferent connections of the feline nucleus tegmenti pedunculopontinus. pars compacta, J. comp. Neurol., 217, 187, 10.1002/cne.902170207 · DOI
  30. Morrison, 1978, The distribution and orientation of noradrenergic libers in neocortcx of the rat: an immunofluoresccnce study, J. comp. Neurol., 181, 17, 10.1002/cne.901810103 · DOI
  31. Moruzzi, 1949, Brain stem reticular formation and activation of the EEG, Electroenceph. clin Neurophysiol., 1, 455, 10.1016/0013-4694(49)90219-9 · DOI · Paper page
  32. Myers, 1970, The spontaneous release of 5-hydroxytriptamine and acctylcholine within the diencephalon ol the unanesthetized rhesus monkey, Expl Brain Res., 11, 539, 10.1007/BF00233974 · DOI
  33. Niimi, 1978, Cortical projections of the anterior thalamic nuclei in the cat, Expl Brain Res., 31, 403, 10.1007/BF00237298 · DOI
  34. Olivier, 1970, Identification of the thalamic nuclei on the basis of their cholinesterase content in the monkey, J. Anat., 106, 37
  35. Ottersen, 1983, Retrograde transport ofd-[3H] aspartate in thalamocortical neurones, Neurosci. Lett., 42, 19, 10.1016/0304-3940(83)90415-9 · DOI
  36. Paré, 1988, Projections of upper brainstem cholinergic and non-cholinergic neurons of cat to intralaminar and reticular thalamic nuclei, Neuroscience, 25, 69, 10.1016/0306-4522(88)90007-3 · DOI
  37. Paré, 1987, Physiological properties of anterior thalamic nuclei, a group devoid of inputs from reticular thalamic nucleus, J. Neurophysiol., 57, 1669, 10.1152/jn.1987.57.6.1669 · DOI
  38. Parent, 1981, Organization of ascending serotonin systems in the adult rat brain. A radiographic study after intraventricular administration of3H-5-hydroxytryptamine, Neuroscience, 6, 115, 10.1016/0306-4522(81)90050-6 · DOI
  39. Partlow, 1977, Thalamic projections of the superior colliculus in the rhesus monkey. Macaca mulatto: a light and electron microscopic study, J. comp. Neurol., 171, 285, 10.1002/cne.901710302 · DOI
  40. Phyllis, 1968, Acetylcholine release from the feline thalamus, J. Pharmac., 20, 477
  41. Robertson, 1981, Thalamic connections with limbic cortex. I. Thalamocortical projections, J. comp. Neurol., 195, 501, 10.1002/cne.901950308 · DOI
  42. Rodrigo-Angulo, 1982, Topographical organization of the brainstem afferents to the lateral posterior-pulvinar thalamic complex in the cat, Neuroscience, 7, 1495, 10.1016/0306-4522(82)90260-3 · DOI
  43. Ropert, 1981, Input-output organization of the midbrain reticular core, J. Neurophysiol., 46, 1731, 10.1152/jn.1981.46.1.17 · DOI
  44. Rotter, 1981, Neurochemical identification of cholinergic forebrain projection sites of the nucleus tegmentalis dorsalis lateralis, Bain Res. Bull., 6, 525, 10.1016/S0361-9230(81)80027-5 · DOI
  45. Rye, 1984, Stabilization of the tetramethylbenzidine (TMB) reaction product, J. Histochem. Cytochem., 32, 1145, 10.1177/32.11.6548485 · DOI
  46. Satoh, 1985, Distribution of central cholinergic neurons in the baboon (Papio pupio). II. A topographical atlas correlated with catecholamine neurons, J. comp. Neurol., 236, 215, 10.1002/cne.902360206 · DOI
  47. Satoh, 1986, Cholinergic neurons of the laterodorsal tegmental nucleus: efferent and afferent connections, J. comp. Neurol., 253, 277, 10.1002/cne.902530302 · DOI
  48. Shute, 1967, The ascending cholinergic ascending reticular system: neocortical, of factory and subcortical projections, Brain, 90, 497, 10.1093/brain/90.3.497 · DOI
  49. Simon, 1973, The role of the raphe nuclei in the regulation of ponto-geniculooccipital wave activity, Brain Res., 58, 313, 10.1016/0006-8993(73)90004-8 · DOI
  50. Singer, 1977, Control of thalamic transmission by corticofugal and ascending reticular pathways, Physiol. Rev., 57, 386, 10.1152/physrev.1977.57.3.386 · DOI
  51. Sofroniew, 1985, Cholinergic projections from the midbrain and pons to the thalamus in rat, identified by combined retrograde tracing and choline acetyltransferase imunohistochemistry, Brain Res., 329, 213, 10.1016/0006-8993(85)90527-X · DOI
  52. Steriade, 1970, Ascending control of thalamic and cortical responsiveness, Int. Rev. Neurobiol., 12, 87, 10.1016/S0074-7742(08)60059-8 · DOI
  53. Steriade, 1971, Control of unitary activities in cerebellothalamic pathway during wakefulness and synchronized sleep, J. Neurophysiol., 34, 384, 10.1152/jn.1971.34.3.389 · DOI
  54. Steriade, 1984, The thalamus as a neuronal oscillator, Brain Res. Rev., 8, 1, 10.1016/0165-0173(84)90017-1 · DOI · Paper page
  55. Steriade, 1977, Some synaptic inputs and ascending projections of lateralis posterior thalamic neurons, Brain Res., 131, 39, 10.1016/0006-8993(77)90027-0 · DOI
  56. Steriade, 1982, The neocortical and caudate projections of intralaminar thalamic neurons and their synaptic excitation from the midbrain core, J. Neurophysiol., 48, 352, 10.1152/jn.1982.48.2.352 · DOI
  57. Steriade, 1976, Neuronal activity during the sleep-waking cycle, Prog. Neurobiol., 6, 155, 10.1016/0301-0082(76)90013-7 · DOI
  58. Steriade, 1982, Firing rates and patterns of midbrain reticular neurons during steady and transitional states of the sleep-waking cycle, Expl Brain Res., 46, 37, 10.1007/BF00238096 · DOI
  59. Steriade, 1984, Thalamic projections of nucleus reticularis thalami of cat: a study using retrograde transport of horseradish peroxidase and double fluorescent tracers, J. comp. Neurol., 229, 531, 10.1002/cne.902290407 · DOI
  60. Steriade, 1987, Cholinergic and non-cholinergic of cat basal forebrain project to reticular and mediodorsal thalamic nuclei, Brain Res., 408, 372, 10.1016/0006-8993(87)90408-2 · DOI
  61. Szerb, 1967, Cortical acetylcholine release and electroencephalographic arousal, J. Physiol., 192, 329, 10.1113/jphysiol.1967.sp008303 · DOI
  62. Tigges, 1985, Subcortical sources of direct projections to visual cortex, Vol. 3, 351
  63. Velayos, 1982, Topographic organization of the brainstem afferents to the mediodorsal thalamic nucleus, J. comp. Neurol., 206, 17, 10.1002/cne.902060104 · DOI
  64. Vincent, 1983, Substance P in the ascending cholinergic system, Nature, 306, 688, 10.1038/306688a0 · DOI
  65. Vincent, 1986, Neuropeptides and NADPH-diaphorase activity in the ascending cholinergic reticular system of the rat, Neuroscience, 17, 167, 10.1016/0306-4522(86)90234-4 · DOI
  66. Wilson, 1985, A photographic perspective on the origin, form, course and relations of the acetylcholinesterase-containing fibers of the dorsal tegmental pathway in the rat brain, Brain Res. Rev., 10, 85, 10.1016/0165-0173(85)90001-3 · DOI
  67. Walker, 1940, The medial thalamic nucleus: a comparative anatomical, physiological and clinical study of the nucleus medialis dorsalis thalami, J. comp. Neurol., 73, 87, 10.1002/cne.900730107 · DOI
  68. Woolf, 1986, Cholinergic systems in the rat brain. III. Projections from the pontomesencephalic tegmentum to the thalamus, tectum. basal ganglia and basal forebrain, Brain Res. Bull., 16, 603, 10.1016/0361-9230(86)90134-6 · DOI
  69. Yarita, 1980, A transthalamic olfactory pathway to orbitofrontal cortex in the monkey, J. Neurophysiol., 43, 69, 10.1152/jn.1980.43.1.69 · DOI

Cited by

Sorted by citations

See all 252

Metadata

Authors
Steriade, M., Paré, D., Parent, A., & Smith, Y.
Venue
Neuroscience
Publisher
Elsevier BV
Published
1988-04
Volume
25
Issue
1
Pages
47-67
ISSN
0306-4522
DOI
10.1016/0306-4522(88)90006-1
Cited by
252
References
3
Language
en
Licence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey. https://app.cochat.ai/papers/10.1016/0306-4522(88)90006-1
The paper
Steriade, M., Paré, D., Parent, A., & Smith, Y. (1988). Projections of cholinergic and non-cholinergic neurons of the brainstem core to relay and associational thalamic nuclei in the cat and macaque monkey. Neuroscience. https://doi.org/10.1016/0306-4522(88)90006-1