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Cited by 935

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Plastics additives handbook

·1991·Additives for Polymers

Abstract

Ion mobility spectrometry in conjunction with liquid chromatography separations and mass spectrometry offers a range of new possibilities for analyzing complex biological samples. To fully utilize the information obtained from these three measurement dimensions, informatics tools based on the accurate mass and time tag methodology were modified to incorporate ion mobility spectrometry drift times for peptides observed in human serum. In this work a reference human serum database was created for 12,139 peptides and populated with the monoisotopic mass, liquid chromatography normalized elution time, and ion mobility spectrometry drift time(s) for each. We demonstrate that the use of three dimensions for peak matching during the peptide identification process resulted in an increased numbers of identifications and a lower false discovery rate relative to only using the mass and normalized elution time dimensions.

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Metadata

Venue
Additives for Polymers
Published
1991-05
Volume
1991
Issue
5
Pages
15
ISSN
0306-3747 (ISSN-L)
OpenAlex
W565168849
Cited by
935
References
0
FWCI
10.18
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Plastics additives handbook. https://app.cochat.ai/papers/10.1016/0306-3747(91)90486-6
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Plastics additives handbook. (1991). Additives for Polymers. https://doi.org/10.1016/0306-3747(91)90486-6

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Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.