The DOI matches its Crossref record; 50 of the 53 references it cites were found in a registry or an index.
Hibernation-induced structural changes in synaptic contacts between mossy fibres and hippocampal pyramidal neurons
Abstract
Mossy fibre synapses on the CA3 hippocampal neurons in the brain of ground squirrels repeatedly undergo a striking structural transformation during hibernation. In the middle of hibernation bout the giant complex mossy fibre synapses have a reduced number of dendritic spine infoldings that are smaller and have a decreased number of postsynaptic densities in comparison with mossy fibre synapses of active animals. Two hours after arousal all these parameters of mossy fibre synapses increase and significantly exceed their levels not only in torpid but in active euthermic animals between bouts of torpor. The longer postsynaptic densities and the greater proportion of perforated postsynaptic densities were found soon after arousal. These rapid, reversible and repeated changes indicate a cyclic process of partial denervation/reinnervation of hippocampal neurons by mossy fibres in the course of the innate, stereotyped behaviour.
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“Furthermore, changes in the denervation/reinnervation of CA3 pyramidal neurons by mossy fibres were also found during hibernation/arousal (Popov and Bocharova, 1992) and they were associated with a reversible PHF-like phosphorylation of tau over a similar time course.”
From The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease (2013) · cites this paper as Popov and Bocharova, 1992
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“This implies that reorganization of the cytoskeleton is taking place rapidly and reversibly, and that changes in dendrite length and branching are not “damage,” but a form of structural plasticity.”
From Protective and damaging effects of stress mediators: central role of the brain (2006) · cites this paper as [60]
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Metadata
- Authors
- Popov, V. I., & Bocharova, L. S.
- Affiliations
- Institute of Cell Biophysics (RU)
- Institute of Theoretical and Experimental Biophysics (RU)
- Corresponding author
- Popov, V.I.
- ORCID
- Popov, V.I.
- Venue
- Neuroscience
- Publisher
- Elsevier BV
- Published
- 1992-05
- Volume
- 48
- Issue
- 1
- Pages
- 53-62
- ISSN
- 0306-4522 (ISSN-L)
- OpenAlex
- W2038852586
- Cited by
- 203
- References
- 53
- Citations by year
- 2026: 1 · 2025: 8 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 15 · 2018: 6 · 2017: 12 · 2016: 8 · 2015: 9 · 2014: 8 · 2013: 5 · 2012: 9
- FWCI
- 1.36
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
- Keywords
- hibernation, mossy fiber synapses, CA3 neurons, dendritic spines, postsynaptic density, denervation and reinnervation, arousal, ground squirrels, torpor
- MeSH terms
- Animals, Arousal, Endoplasmic Reticulum, Hibernation, Hippocampus, Microscopy, Electron, Microtubules, Nerve Fibers, Neurons, Pyramidal Tracts, Sciuridae, Synapses
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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