Cited by 203Neuroscience and Neuropharmacology ResearchMemory and Neural MechanismsPhysiological and biochemical adaptations

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Hibernation-induced structural changes in synaptic contacts between mossy fibres and hippocampal pyramidal neurons

Popov, V.I., Bocharova, L.S.·1992·Neuroscience

DOI 10.1016/0306-4522(92)90337-2

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Abstract

Mossy fibre synapses on the CA3 hippocampal neurons in the brain of ground squirrels repeatedly undergo a striking structural transformation during hibernation. In the middle of hibernation bout the giant complex mossy fibre synapses have a reduced number of dendritic spine infoldings that are smaller and have a decreased number of postsynaptic densities in comparison with mossy fibre synapses of active animals. Two hours after arousal all these parameters of mossy fibre synapses increase and significantly exceed their levels not only in torpid but in active euthermic animals between bouts of torpor. The longer postsynaptic densities and the greater proportion of perforated postsynaptic densities were found soon after arousal. These rapid, reversible and repeated changes indicate a cyclic process of partial denervation/reinnervation of hippocampal neurons by mossy fibres in the course of the innate, stereotyped behaviour.

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Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks
Changeux, J.-P., & Danchin, A. (1976) · Nature · doi:10.1038/264705a0 · Cited by 1,448
Synapse replacement in the nervous system of adult vertebrates.
Cotman, C. W., Nieto‐Sampedro, M., & Harris, E. W. (1981) · Physiological Reviews · doi:10.1152/physrev.1981.61.3.684 · Cited by 546
Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl d-aspartate antagonists
Harris, E. W., & Cotman, C. W. (1986) · Neuroscience Letters · doi:10.1016/0304-3940(86)90451-9 · Cited by 540
Transient and enduring morphological correlates of synaptic activity and efficacy change in the rat hippocampal slice
Chang, F., & Greenough, W. T. (1984) · Brain Research · doi:10.1016/0006-8993(84)91008-4 · Cited by 523
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. I. Magnitude and time course of degeneration
Matthews, D. A., Cotman, C. W., & LYNCH, G. S. (1976) · Brain Research · doi:10.1016/0006-8993(76)90819-2 · Cited by 460
Differential rearing effects on rat visual cortex synapses: I. Synaptic and neuronal density and synapses per neuron
Turner, A. M., & Greenough, W. T. (1985) · Brain Research · doi:10.1016/0006-8993(85)90525-6 · Cited by 459
An electron microscopic study of lesion-induced synaptogenesis in the dentate gyrus of the adult rat. II. Reappearance of morphologically normal synaptic contacts
Matthews, D. A., Cotman, C. W., & LYNCH, G. S. (1976) · Brain Research · doi:10.1016/0006-8993(76)90820-9 · Cited by 384
Differential rearing effects on rat visual cortex synapses.
Sirevaag, A. M., & Greenough, W. T. (1987) · Brain Research · doi:10.1016/0006-8993(87)91477-6 · Cited by 370
Long-term memory in Aplysia modulates the total number of varicosities of single identified sensory neurons.
Bailey, C. H., & Chen, M. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.7.2373 · Cited by 283
Cell Biology of Synaptic Plasticity
Cotman, C. W., & Nieto‐Sampedro, M. (1984) · Science · doi:10.1126/science.6382610 · Cited by 275

Show all 53 references

Research works printed but not linked: 5

Derji, 1985, Hibernator's protein synthesis in the neocortex and the hippocampus, Comp. Biochem. Physiol., 80B, 927
Gordon, 1989, Alterations in the state of ribosomes in nerve cells revealed with acridine orange, Tzitologia, 31, 73
Jegunov, 1988, Hyperactivation of protein synthesis in tissues of hibernating animals on arousal, Cryo-Letters, 9, 236
Palladin, 1971, Hibernation, Vol. 4, 489
Shtark, 1972, NASA Tech. Transl. TTF-619

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Authors: Popov, V. I., & Bocharova, L. S.
Affiliations: Institute of Cell Biophysics (RU)
Institute of Theoretical and Experimental Biophysics (RU)
Corresponding author: Popov, V.I.
ORCID: Popov, V.I.
Venue: Neuroscience
Publisher: Elsevier BV
Published: 1992-05
Volume: 48
Issue: 1
Pages: 53-62
ISSN: 0306-4522 (ISSN-L)
DOI: 10.1016/0306-4522(92)90337-2
OpenAlex: W2038852586
Cited by: 203
References: 53
Citations by year: 2026: 1 · 2025: 8 · 2024: 2 · 2023: 5 · 2022: 2 · 2021: 4 · 2020: 4 · 2019: 15 · 2018: 6 · 2017: 12 · 2016: 8 · 2015: 9 · 2014: 8 · 2013: 5 · 2012: 9
FWCI: 1.36
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Physical Sciences › Environmental Science › Ecology › Physiological and biochemical adaptations
Keywords: hibernation, mossy fiber synapses, CA3 neurons, dendritic spines, postsynaptic density, denervation and reinnervation, arousal, ground squirrels, torpor
MeSH terms: Animals, Arousal, Endoplasmic Reticulum, Hibernation, Hippocampus, Microscopy, Electron, Microtubules, Nerve Fibers, Neurons, Pyramidal Tracts, Sciuridae, Synapses

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Hibernation-induced structural changes in synaptic contacts between mossy fibres and hippocampal pyramidal neurons

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