Cited by 2,033Cardiovascular Health and Disease PreventionNitric Oxide and Endothelin EffectsCardiovascular Function and Risk Factors

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Close relation of endothelial function in the human coronary and peripheral circulations

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Anderson, Todd J., Uehata, Akimi, Gerhard, Marie D., Meredith, Ian T., Knab, Sarah, Delagrange, Danielle, Lieberman, Eric H., Ganz, Peter, Creager, Mark A., Yeung, Alan C., Selwyn, Andrew P.·1995·Journal of the American College of Cardiology

DOI 10.1016/0735-1097(95)00327-4

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Abstract

Objectives The relation between endothelium-dependent vasodilator function in the brachial and coronary arteries was determined in the same subjects.Background Coronary artery endothelial dysfunction precedes the development of overt atherosclerosis and is important in its pathogenesis. A noninvasive assessment of endothelial function in a peripheral conduit vessel, the brachial artery, was recently described, but the relation between brachial artery function and coronary artery vasodilator function has not been explored.Methods In 50 patients referred to the catheterization laboratory for the evaluation of coronary artery disease (mean age +/- SD 56 +/- 10 years), the coronary vasomotor response to serial intracoronary infusions of the endothelium-dependent agonist acetylcholine (10(-8) to 10(-6) mol/liter), was studied. Endothelium-dependent vasodilation was also assessed in the brachial artery by measuring the change in brachial artery diameter in response to reactive hyperemia.Results Patients with coronary artery endothelial dysfunction manifested as vasoconstriction in response to acetylcholine had significantly impaired flow-mediated vasodilation in the brachial artery compared with that of patients with normal coronary endothelial function (4.8 +/- 5.5% vs. 10.8 +/- 7.6%, p < 0.01). Patients with coronary artery disease also had an attenuated brachial artery vasodilator response compared with that of patients with angiographically smooth coronary arteries (4.5 +/- 4.6% vs. 9.7 +/- 8.1%, p < 0.02). By multivariate analysis, the strongest predictors of reduced brachial dilator responses to flow were baseline brachial artery diameter (p < 0.001), coronary endothelial dysfunction (p = 0.003), the presence of coronary artery disease (p = 0.007) and cigarette smoking (p = 0.016). The brachial artery vasodilator response to sublingual nitroglycerin was independent of coronary endothelial responses or the presence of coronary artery disease. The positive predictive value of abnormal brachial dilation ( < 3%) in predicting coronary endothelial dysfunction is 95%.Conclusions This study demonstrated a close relation between coronary artery endothelium-dependent vasomotor responses to acetylcholine and flow-mediated vasodilation in the brachial artery. This noninvasive method may become a useful surrogate in assessing the predisposition to atherosclerosis in patients with cardiac risk factors.

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The L-Arginine-Nitric Oxide Pathway
Epstein, F. H., Moncada, S., & Higgs, A. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312303292706 · Cited by 6,678
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Celermajer, D. S., Sorensen, K. E., Gooch, V. M., Spiegelhalter, D. J., Miller, O. I., Sullivan, I. D., Lloyd, J. K., & Deanfield, J. E. (1992) · The Lancet · doi:10.1016/0140-6736(92)93147-f · Cited by 4,742
Paradoxical Vasoconstriction Induced by Acetylcholine in Atherosclerotic Coronary Arteries
Ludmer, P. L., Selwyn, A. P., Shook, T., Wayne, R. R., Mudge, G. H., Alexander, R. W., & Ganz, P. (1986) · New England Journal of Medicine · doi:10.1056/nejm198610233151702 · Cited by 2,422
Abnormal Endothelium-Dependent Vascular Relaxation in Patients with Essential Hypertension
Panza, J. A., Quyyumi, A. A., Brush, J. E., & Epstein, S. E. (1990) · New England Journal of Medicine · doi:10.1056/nejm199007053230105 · Cited by 2,366
Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man
Vallance, P., Collier, J., & Moncada, S. (1989) · The Lancet · doi:10.1016/s0140-6736(89)91013-1 · Cited by 1,590
Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.
Celermajer, D. S., Sørensen, K. E., Georgakopoulos, D., Bull, C., Thomas, O., Robinson, J. T. C., & Deanfield, J. E. (1993) · Circulation · doi:10.1161/01.cir.88.5.2149 · Cited by 1,532
Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.
Vita, J. A., Treasure, C. B., Nabel, E. G., McLenachan, J. M., Fish, R. D., Yeung, A. C., Vekshtein, V. I., Selwyn, A. P., & Ganz, P. (1990) · Circulation · doi:10.1161/01.cir.81.2.491 · Cited by 1,172
Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans.
Creager, M. A., Cooke, J. P., Mendelsohn, M. E., Gallagher, S. J., Coleman, S. M., Loscalzo, J., & Dzau, V. J. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114688 · Cited by 1,017
Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis.
Zeiher, A. M., Drexler, H., Wollschläger, H., & Just, H. (1991) · Circulation · doi:10.1161/01.cir.83.2.391 · Cited by 994
Crucial role of endothelium in the vasodilator response to increased flow in vivo.
Pohl, U., Holtz, J., Busse, R., & Bassenge, E. (1986) · Hypertension · doi:10.1161/01.hyp.8.1.37 · Cited by 984

Show all 24 references

Research works printed but not linked: 6

Meredith, 1993, Role of impaired endotheliumdependent vasodilation in ischemic manifestations of coronary artery disease, Circulation, 87, V
Lefroy, 1993, Effects of nitric oxide in the human coronary circulation, Circulation, 88, I
Dyce, 1993, The relationship between endothelial vasodilator function and LDL particle size, density and number in human coronary atherosclerosis, Circulation, 88, 1
Lieberman, 1993, Flow-mediated vasodilation is impaired in the brachial artery of patients with coronary artery disease or with diabetes mellitus, Clin Res, 41, 217A
Uehata, 1992, Non-invasive assessment of flow-mediated vasodilation in brachial arteries: diminished response in young males compared to females, Circulation, 86, I
Lieberman, 1994, Nitric oxide mediates the vasodilator response to flow in humans, Circulation, 90, I

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Endothelial function, arterial stiffness and lipid lowering drugs
Τζιόμαλος, Κ., Athyros, V. G., Karagiannis, A. I., & Mikhailidis, D. P. (2007) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.11.9.1143 · Cited by 41
“FMD correlates with invasively measured coronary endothelial function [47,48] and was shown to be a sensitive screening test for the presence of CAD [49,50] .”
Background
Retinal microvasculature impairments in patients with coronary artery disease: An optical coherence tomography angiography study
Zhong, P., Li, Z., Lin, Y., Peng, Q., Huang, M., Jiang, L., Li, C., Kuang, Y., Cui, S., Yu, D., et al. (2021) · Acta Ophthalmologica · doi:10.1111/aos.14806 · Cited by 42
“At present, the study to explore the potential relationship between CAD and retinal microvasculature measured by OCTA is of interest but scarce (Arnould et al. 2018; Wang et al. 2019).”
Background
Clinical practice
Cohen, M. S. (2012) · European Journal of Pediatrics · doi:10.1007/s00431-012-1736-2 · Cited by 42
Limitations of non‐invasive endothelial function assessment by brachial artery flow‐mediated dilatation
Šejda, T., Pitha, J. V., Svandova, E., & Poledne, R. (2005) · Clinical Physiology and Functional Imaging · doi:10.1111/j.1475-097x.2004.00590.x · Cited by 42
“Endothelial dysfunction can be considered the first, functionally significant stage of atherosclerosis (Anderson et al., 1995; Šejda et al., 2002).”
Background
Geographic Origin as a Determinant of Carotid Artery Intima-Media Thickness and Brachial Artery Flow-Mediated Dilation
Juonala, M., Viikari, J. S. A., Kähönen, M. A. P., Taittonen, L. M., Rönnemaa, T., Laitinen, T. P., Mäki-Torkko, N., Mikkilä, V., Räsänen, L., Åkerblom, H. K., et al. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000150042.43866.7f · Cited by 42
Pathological Changes in Acute Coronary Syndromes: The Role of Statin Therapy in the Modulation of Inflammation, Endothelial Function and Coagulation
Ray, K., & Cannon, C. (2004) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-004-0205-9 · Cited by 43
“Endothelial dysfunction refers to the diminished vasodilator reserve in the peripheral and coronary circulation in response to acetylcholine or reactive hyperaemia [34].”
Background
N-3 polyunsaturated fatty acids early supplementation improves ultrasound indices of endothelial function, but not through NO inhibitors in patients with acute myocardial infarctionN-3 PUFA supplementation in acute myocardial infarction.
Haberka, M., Mizia‐Stec, K., Mizia, M., Janowska, J., Gieszczyk-Strózik, K., Chmiel, A., Zahorska‐Markiewicz, B., & Gąsior, Z. (2010) · Clinical Nutrition · doi:10.1016/j.clnu.2010.07.011 · Cited by 41
Nitric Oxide Synthase-Dependent Vasodilation of Human Subcutaneous Arterioles Correlates With Noninvasive Measurements of Endothelial Function
Dharmashankar, K., Welsh, A. C., Wang, J., Kizhakekuttu, T. J., Ying, R., Gutterman, D. D., & Widlansky, M. E. (2012) · American Journal of Hypertension · doi:10.1038/ajh.2012.8 · Cited by 41
Divergent Effects of Joyful and Anxiety-Provoking Music on Endothelial Vasoreactivity
Miller, M. J., Mangano, C. C., Beach, V., Kop, W. J., & Vogel, R. A. (2010) · Psychosomatic Medicine · doi:10.1097/psy.0b013e3181da7968 · Cited by 41
“FMD is correlated with the intracoronary vasomotor response post acetylcholine administration (4,5), and reduced endothelial vasoreactivity has been consistently identified in subjects with diabetes mellitus, hyperlipidemia, cigarette smoking, and hypertension (1).”
Background
Improvement of Endothelial Dysfunction with Simvastatin in Patients with Autosomal Dominant Polycystic Kidney Disease
Namli, Ş., Oflaz, H., Turgut, F. H., Alışır, S., Tufan, F., Uçar, A., Mercanoğlu, F., & Ecder, T. (2007) · Renal Failure · doi:10.1080/08860220601038892 · Cited by 41
“Brachial artery ED correlates with coronary ED (20).”
Black Tea Increases Circulating Endothelial Progenitor Cells and Improves Flow Mediated Dilatation Counteracting Deleterious Effects from a Fat Load in Hypertensive Patients: A Randomized Controlled Study
Grassi, D., Draijer, R., Schalkwijk, C. G., Desideri, G., D’Angeli, A., Francavilla, S., MULDER, T. P. J., & Ferri, C. (2016) · Nutrients · doi:10.3390/nu8110727 · Cited by 42
The impact of particulate matter air pollution (PM2.5) on atherosclerosis in modernizing China: a report from the CATHAY study
Woo, K. S., Chook, P., Hu, Y., Lao, X. Q., Lin, C., Lee, P., Kwok, C., Wei, A., Guo, D., Yin, Y., et al. (2020) · International Journal of Epidemiology · doi:10.1093/ije/dyaa235 · Cited by 41
Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Alley, H. F., Owens, C. D., Gasper, W. J., & Grenon, S. M. (2014) · Journal of Visualized Experiments · doi:10.3791/52070 · Cited by 41
Endothelial Dysfunction and Cytomegalovirus Replication in Pediatric Heart Transplantation
Simmonds, J., Fenton, M. J., Dewar, C., Ellins, E. A., Storry, C., Cubitt, D. W., Deanfield, J. E., Klein, N. J., Halcox, J., & Burch, M. (2008) · Circulation · doi:10.1161/circulationaha.107.718874 · Cited by 41
Clinical correlates of endothelial function in chronic heart failure
Ciccone, M. M., Iacoviello, M., Puzzovivo, A., Scicchitano, P., Monitillo, F., Crescenzo, F. D., Caragnano, V., Sassara, M., Quistelli, G., Guida, P., et al. (2011) · Clinical Research in Cardiology · doi:10.1007/s00392-010-0275-y · Cited by 41
“Since it has been shown that peripheral endothelial function is linked with coronary vasodilation [5], the M.”
Background
Association between vascular dysfunction and reduced myocardial flow reserve in patients with hypertension: a LIFE substudy
Olsen, M. H., Wachtell, K., Meyer, C. G., Hove, J. D., Palmieri, V., Dige‐Petersen, H., Rokkedal, J. E., Hesse, B., & Ibsen, H. (2004) · Journal of Human Hypertension · doi:10.1038/sj.jhh.1001716 · Cited by 41
Endothelial function and endothelial nitric oxide synthase intron 4a/b polymorphism in primary hyperparathyroidism
Ekmekçi, A., Abacı, N., Özbey, N., Agayev, A., Aksakal, N., Oflaz, H., Erginel‐Ünaltuna, N., & Erbil, Y. (2009) · Journal of Endocrinological Investigation · doi:10.1007/bf03346518 · Cited by 41
Endothelial dysfunction in type 2 diabetes mellitus subjects with peripheral artery disease
Yu, H.-I., Sheu, W. H., Lai, C.-J., Lee, W.-J., & Chen, Y.-T. (2001) · International Journal of Cardiology · doi:10.1016/s0167-5273(00)00423-x · Cited by 41
Impairment of endothelial function after a high-fat meal in patients with coronary artery disease
Zhao, S., Liu, L., Gao, M., Zhou, Q., Li, Y.-L., & Xia, B. (2001) · Coronary Artery Disease · doi:10.1097/00019501-200111000-00006 · Cited by 41
Relation between endothelial dysfunction and the acute coronary syndrome: implications for therapy
Kinlay, S., & Ganz, P. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)01334-5 · Cited by 41
Need for standardization of noninvasive assessment of vascular endothelial function
Kuvin, J. T., Patel, A. R., & Karas, R. H. (2001) · American Heart Journal · doi:10.1067/mhj.2001.113221 · Cited by 41
Observations of time-based measures of flow-mediated dilation of forearm conduit arteries: implications for the accurate assessment of endothelial function
Liuni, A., Luca, M. C., Lisi, M., Dragoni, S., Stolfo, G. D., Mariani, J. A., Uxa, A., Gori, T., & Parker, J. D. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00271.2010 · Cited by 40
“Measured this way, FMD correlates with coronary endothelial function (1) and is blunted in a number of cardiovascular conditions, including coronary artery disease (CAD), hypertension (HTN), and heart failure (HF), as well as in preclinical subjects with risk factors for atherosclerosis (21, 23, 24).”
Background
Coronary artery endothelial dysfunction is present in HIV-positive individuals without significant coronary artery disease
Iantorno, M., Schär, M., Soleimanifard, S., Brown, T. T., Moore, R., Barditch‐Crovo, P., Stuber, M., Lai, S., Gerstenblith, G., Weiss, R. G., et al. (2017) · AIDS · doi:10.1097/qad.0000000000001469 · Cited by 40
“Although systemic endothelial dysfunction was reported in HIVþ people [7], peripheral artery endothelial function correlates only modestly with CEF [8], and the latter is more closely”
Background
Endothelial Cell Dysfunction
Davidge, S. T., de Groot, C. J. M., & Taylor, R. N. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-407866-6.00009-2 · Cited by 41
Evaluation of the effect of l-thyroxin therapy on endothelial functions in patients with subclinical hypothyroidism
Alıbaz-Öner, F., Yurdakul, S., Öner, E., Üzüm, A. K., & Ergüney, M. (2011) · Endocrine · doi:10.1007/s12020-011-9465-2 · Cited by 39
“Endothelial dysfunction has been reported in patients with overt and subclinical hypothyroidism [ 7 , 8]. As an early stage of atherosclerosis, endothelial dysfunction is associated with increased risk of cardiovascular events [9, 10].”
Background
Reproducibility of the Flow-Mediated Dilation Response to Acute Exercise in Overweight Men
Harris, R. A., Padilla, J., Hanlon, K. P., Rink, L. D., & Wallace, J. P. (2007) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2007.04.014 · Cited by 40
Clinical impact of vasomotor function assessment and the role of ACE-inhibitors and statins
Asselbergs, F. W., van der Harst, P., Jessurun, G. A. J., Tio, R. A., & van Gilst, W. H. (2005) · Vascular Pharmacology · doi:10.1016/j.vph.2005.01.009 · Cited by 40
“…1994) hypercholesterolemia 9 CEDV pravastatin 6 months + Treasure (Treasure et al. 1995) CAD 23 CEDV lovastatin 12 days / 5.5 months - / + Anderson (Anderson et al. 1995a) Cholesterol 49 CEDV lovastatin 1 year + (4.7-7.2 mmol/l) cholestyramide probucol Houghton (Houghton et al. 2000) Normal…”
BackgroundInfluential
Endothelial dysfunction of peripheral arteries in patients with immunohistologically confirmed myocardial inflammation correlates with endothelial expression of human leukocyte antigens and adhesion molecules in myocardial biopsies
Vallbracht, K. B., Schwimmbeck, P. L., Seeberg, B., Kühl, U., & Schultheiß, H. (2002) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(02)01990-3 · Cited by 40
“function has been demonstrated for other diseases (12).”
Background
Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial
Arosio, E., Marchi, S. D., Zannoni, M., Prior, M., & Lechi, A. (2002) · Mayo Clinic Proceedings · doi:10.4065/77.8.754 · Cited by 40
Oestradiol improves arterial endothelial function in healthy men receiving testosterone
Sader, M. A., McCredie, R. J., Griffiths, K. A., Wishart, S. M., Handelsman, D. J., & Celermajer, D. S. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01176.x · Cited by 40
“Although we tested brachial artery responses, brachial FMD measurement reflects predominantly nitric oxide release (Joannides et al., 1995) and correlates significantly with coronary endothelial function (Anderson et al., 1995) and coronary atherosclerosis (Neunteufl et al., 1997).”
BackgroundMethod
Flow-mediated dilatation of the brachial artery and left ventricular geometry in hypertensive patients
Muiesan, M. L., Salvetti, M., Monteduro, C., Corbellini, C., Guelfi, D., Rizzoni, D., Castellano, M., & Agabiti‐Rosei, E. (2001) · Journal of Hypertension · doi:10.1097/00004872-200103001-00018 · Cited by 40
Endothelin receptor blockade improves endothelial function in atherosclerotic patients on angiotensin converting enzyme inhibition
Böhm, F., BELTRAN, E., & Pernow, J. (2005) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2005.01448.x · Cited by 40
Evaluation of Risk Factors That Contribute to High Prevalence of Premature Atherosclerosis in Chinese Premenopausal Systemic Lupus Erythematosus Patients
Zhang, C., Lu, L., Li, F., Li, H., Gu, Y., Chen, S., & Bao, C. (2009) · JCR Journal of Clinical Rheumatology · doi:10.1097/rhu.0b013e31819d8489 · Cited by 38
“There is a significant correlation between FMD in the brachial and coronary circulations.(11) Impaired endothelium-dependent FMD has been associated with adverse cardiovascular outcomes.”
BackgroundInfluential
Endothelial Dysfunction and Brachial Intima-Media Thickness: Long Term Cardiovascular Risk with Claudication Related to Peripheral Arterial Disease: A Prospective Analysis
Hafner, F., Kieninger‐Gräfitsch, A., Meinitzer, A., Gary, T., Froehlich, H., Haas, E., Hackl, G., Eller, P., Brodmann, M., & Seinost, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093357 · Cited by 39
“Brachial flow-mediated dilatation (FMD) is a validated, non-invasive ultrasound technique that measures endothelial dysfunction to predict cardiovascular risk [4,5,6,7].”
Background
Following the Arterial Switch Operation, Obese Children have Risk Factors for Early Cardiovascular Disease
Pasquali, S. K., Marino, B. S., Powell, D. J., McBride, M. G., Paridon, S. M., Meyers, K. E. C., Mohler, E. R., Walker, S. A., Kren, S., & Cohen, M. S. (2010) · Congenital Heart Disease · doi:10.1111/j.1747-0803.2009.00359.x · Cited by 39
Assessment of subclinical atherosclerosis in systemic lupus erythematosus: A systematic review and meta-analysis
Henrot, P., Foret, J., Barnetche, T., Lazaro, E., Duffau, P., Sénéschal, J., Schaeverbeke, T., Truchetet, M., & Richez, C. (2017) · Joint Bone Spine · doi:10.1016/j.jbspin.2017.12.009 · Cited by 39
Nitric oxide contributes to cerebrovascular shear‐mediated dilatation but not steady‐state cerebrovascular reactivity to carbon dioxide
Hoiland, R. L., Caldwell, H. G., Carr, J. M. J. R., Howe, C. A., Stacey, B. S., Dawkins, T. G., Wakeham, D. J., Tremblay, J. C., Tymko, M. M., Patrician, A., et al. (2021) · The Journal of Physiology · doi:10.1113/jp282427 · Cited by 39
“Of these mechanisms, nitric oxide (NO)-mediated signal transduction has been considered a leading candidate mechanism, with NO-dependent function known to be indicative of vascular health (Anderson et al. 1995; Green et al. 2011).”
Background
Restoring the Dysfunctional Endothelium
Osto, E., Coppolino, G., Volpe, M., & Cosentino, F. (2007) · Current Pharmaceutical Design · doi:10.2174/138161207780487566 · Cited by 39
The assessment of endothelial function in humans
Farouque, H. M. O., & Meredith, I. T. (2001) · Coronary Artery Disease · doi:10.1097/00019501-200109000-00003 · Cited by 39
Arterial elasticity identified by pulse wave analysis and its relation to endothelial function in patients with coronary artery disease
Tao, J., Liu, D.-H., Wang, L.-C., Wang, J.-M., Wang, Y., Yang, Z., Lou, Z.-F., & Tang, A.-L. (2006) · Journal of Human Hypertension · doi:10.1038/sj.jhh.1002112 · Cited by 39
Can the measurement of brachial artery flow-mediated dilation be applied to the acute exercise model?
Padilla, J., Harris, R. A., & Wallace, J. P. (2007) · Cardiovascular Ultrasound · doi:10.1186/1476-7120-5-45 · Cited by 38
Improvement of Endothelial Dysfunction in Acromegaly after Transsphenoidal Surgery
Sakai, H., Tsuchiya, K., Nakayama, C., Iwashima, F., Izumiyama, H., Doi, M., Yoshimoto, T., TSUJINO, M., Yamada, S., & Hirata, Y. (2008) · Endocrine Journal · doi:10.1507/endocrj.k07e-125 · Cited by 38
“However, it is controversial whether excessive secretion of GH and IGF-1 and/or multiple risk factors associated with acromegaly contribute to the development of CVD.”
BackgroundInfluential

Authors: Anderson, T. J., Uehata, A., Gerhard, M. D., Meredith, I. T., Knab, S., Delagrange, D., Lieberman, E. H., Ganz, P., Creager, M. A., Yeung, A. C., & Selwyn, A. P.
Affiliations: Brigham and Women's Hospital (US)
ORCID: Anderson, Todd J.
Meredith, Ian T.
Ganz, Peter
Creager, Mark A.
Yeung, Alan C.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 1995-11
Volume: 26
Issue: 5
Pages: 1235-1241
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/0735-1097(95)00327-4
OpenAlex: W1980445357
Cited by: 2,033
References: 24
Citations by year: 2026: 10 · 2025: 18 · 2024: 26 · 2023: 30 · 2022: 25 · 2021: 50 · 2020: 47 · 2019: 42 · 2018: 41 · 2017: 61 · 2016: 67 · 2015: 72 · 2014: 82 · 2013: 75 · 2012: 66
FWCI: 25.71
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 6467 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5k04hl002566-04, 5k08hl002787-05, 5k07hl002663-02)
National Heart, Lung, and Blood Institute (HL02663, 1K04-HL-02566, 1K08 HL-02787)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
Keywords: endothelial dysfunction, coronary artery disease, brachial artery flow-mediated dilation, coronary vasodilation, acetylcholine, reactive hyperemia, cigarette smoking, nitroglycerin, atherosclerosis risk prediction, coronary artery disease screening, brachial artery diameter, vasoconstriction
MeSH terms: Acetylcholine, Adult, Aged, Brachial Artery, Coronary Artery Disease, Coronary Vessels, Endothelium, Vascular, Female, Nitroglycerin, Cardiac Catheterization, Humans, Male, Middle Aged, Predictive Value of Tests, Vasodilation, Vasodilator Agents

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Close relation of endothelial function in the human coronary and peripheral circulations

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