Substance Use Disorders in a Primary Care Sample Receiving Daily Opioid Therapy

Fleming, Michael F.; Balousek, Stacey L.; Klessig, Cynthia L.; Mundt, Marlon P.; Brown, David D.

doi:10.1016/j.jpain.2007.02.432

Cited by 274Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesPain Management and Opioid Use

Substance Use Disorders in a Primary Care Sample Receiving Daily Opioid Therapy

Open access

Fleming, Michael F., Balousek, Stacey L., Klessig, Cynthia L., Mundt, Marlon P., Brown, David D.·2007·The Journal of Pain

DOI 10.1016/j.jpain.2007.02.432PMC PMC1959336

Open this paper in CoChat — free account

Abstract

Unlabelled The primary goal of this paper was to present a comprehensive picture of substance use disorders in a sample of patients receiving opioid therapy from their primary care physician. A second goal was to determine the relation of positive urine screens and aberrant drug behaviors to opioid use disorders. The study recruited 801 adults receiving daily opioid therapy from the primary care practices of 235 family physicians and internists in 6 health care systems in Wisconsin. The 6 most common pain diagnoses were degenerative arthritis, low back pain, migraine headaches, neuropathy, and fibromyalgia. The point prevalence of current (DSM-IV criteria in the past 30 days) substance abuse and/or dependence was 9.7% (n=78) and 3.8% (30) for an opioid use disorder. A logistic regression model found that current substance use disorders were associated with age between 18 and 30 (OR=6.17: 1.99 to 19.12), severity of lifetime psychiatric disorders (OR=6.17; 1.99 to 19.12), a positive toxicology test for cocaine (OR=5.92; 2.60 to 13.50) or marijuana (OR=3.52; 1.85 to 6.73), and 4 aberrant drug behaviors (OR=11.48; 6.13 to 21.48). The final model for opioid use disorders was limited to aberrant behaviors (OR=48.27; 13.63 to 171.04) as the other variables dropped out of the model. Perspective This study found that the frequency of opioid use disorders was 4 times higher in patients receiving opioid therapy compared with general population samples (3.8% vs 0.9%). The study also pro…

Integrity signals

Registry

Crossref · 10.1016/j.jpain.2007.02.432

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Approximately 10% of individuals with chronic pain have active substance abuse and/or dependence.
“It has been estimated that approximately 10% of individuals with chronic pain have active substance abuse and/or dependence18”
From Telehealth Versus In-Person Acceptance and Commitment Therapy for Chronic Pain: A Randomized Noninferiority Trial. (2017) · cites this paper as [18]

The Fifth Edition of the Addiction Severity Index.
Mclellan, A., Kushner, H., Metzger, D., Peters, R., Smith, I. E., Grissom, G. R., Pettinati, H., & Argeriou, M. (1992) · Journal of Substance Abuse Treatment · doi:10.1016/0740-5472(92)90062-s · Cited by 4,279 · see citing works
Lost productive time and cost due to common pain conditions in the US workforce
Stewart, W. F. (2003) · JAMA · doi:10.1001/jama.290.18.2443 · Cited by 1,570 · see citing works
Persistent Pain and Well-being: A World Health Organization Study in Primary Care
Gureje, O., Von Korff, M., Simon, G. E., & Gater, R. (1998) · JAMA · doi:10.1001/jama.280.2.147 · Cited by 1,496 · see citing works
Results From the 2008 National Survey on Drug Use and Health: National Findings
(2009) · PsycEXTRA Dataset · doi:10.1037/e592592009-001 · Cited by 1,178 · see citing works
Addiction Rare in Patients Treated with Narcotics
(1980) · New England Journal of Medicine · doi:10.1056/nejm198001103020221 · Cited by 1,106 · see citing works
Predicting aberrant behaviors in opioid-treated patients: preliminary validation of the Opioid Risk Tool
Webster, L. R., & Webster, R. M. (2005) · Pain Medicine · doi:10.1111/j.1526-4637.2005.00072.x · Cited by 1,096 · see citing works
Variations in population health status: results from a United Kingdom national questionnaire survey
Kind, P., Dolan, P., Gudex, C., & Williams, A. (1998) · BMJ · doi:10.1136/bmj.316.7133.736 · Cited by 1,059 · see citing works
Opioid Therapy for Chronic Pain
Ballantyne, J. C., & Mao, J. (2003) · New England Journal of Medicine · doi:10.1056/nejmra025411 · Cited by 960 · see citing works
Major increases in opioid analgesic abuse in the United States: Concerns and strategies
Compton, W. M., & Volkow, N. D. (2005) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2005.05.009 · Cited by 831 · see citing works
Systematic Review: Opioid Treatment for Chronic Back Pain: Prevalence, Efficacy, and Association with Addiction
Martell, B. A., O’Connor, P. G., Kerns, R. D., Becker, W. C., Morales, K. H., Kosten, T. R., & Fiellin, D. A. (2007) · Annals of Internal Medicine · doi:10.7326/0003-4819-146-2-200701160-00006 · Cited by 767 · see citing works
Opioid pseudoaddiction — an iatrogenic syndrome
Weissman, D. E., & Haddox, J. D. (1989) · Pain · doi:10.1016/0304-3959(89)90097-3 · Cited by 644 · see citing works
Opioids in pain management
McQuay, H. (1999) · The Lancet · doi:10.1016/s0140-6736(99)03528-x · Cited by 413 · see citing works
Drug Abuse, Dependence, and Addiction in Chronic Pain Patients
Fishbain, D. A., Rosomoff, H. L., & Rosomoff, R. S. (1992) · Clinical Journal of Pain · doi:10.1097/00002508-199206000-00003 · Cited by 359 · see citing works
Use of opioid medications for chronic noncancer pain syndromes in primary care
Reid, M. C., Engles-Horton, L., Weber, M. B., Kerns, R. D., Rogers, E., & O’Connor, P. G. (2002) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2002.10435.x · Cited by 338 · see citing works
Management of pain during debridement: a survey of U.S. burn units
Perry, S. W., & Heidrich, G. (1982) · Pain · doi:10.1016/0304-3959(82)90016-1 · Cited by 329 · see citing works
Opioid Guidelines in the Management of Chronic Non-Cancer Pain
Manchikanti, L. (2006) · Pain Physician · doi:10.36076/ppj.2006/9/2 · Cited by 277 · see citing works
Screening for Addiction in Patients with Chronic Pain and “Problematic” Substance Use
Compton, P. A., Darakjian, J., & Miotto, K. A. (1998) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(98)00110-9 · Cited by 266 · see citing works
Chronic pain: treatment barriers and strategies for clinical practice.
Glajchen, M. (2001) · PubMed · Cited by 224 · see citing works
Primary care provider concerns about management of chronic pain in community clinic populations
Upshur, C., Luckmann, R., & Savageau, J. A. (2006) · Journal of general internal medicine · doi:10.1111/j.1525-1497.2006.00412.x · Cited by 210 · see citing works
Physicians' attitudes and practices regarding the long-term prescribing of opioids for non-cancer pain
Turk, D. C., Brody, M. C., & Okifuji, A. (1994) · Pain · doi:10.1016/0304-3959(94)90072-8 · Cited by 184 · see citing works
Long-term opioid therapy: Assessment of consequences and risks
Savage, S. R. (1996) · Journal of Pain and Symptom Management · doi:10.1016/0885-3924(95)00202-2 · Cited by 176 · see citing works
Attitudes Toward Opioid Use for Chronic Pain: A Canadian Physician Survey
Morley-Forster, P., Clark, A. J., Speechley, M. R., & Moulin, D. E. (2003) · Pain Research and Management · doi:10.1155/2003/184247 · Cited by 154 · see citing works
Does random urine drug testing reduce illicit drug use in chronic pain patients receiving opioids?
Manchikanti, L., Manchukonda, R., Pampati, V., Damron, K. S., Brandon, D. E., Cash, K. A., & McManus, C. D. (2006) · PubMed · Cited by 148 · see citing works
Opioids for chronic nonmalignant pain. Attitudes and practices of primary care physicians in the UCSF/Stanford Collaborative Research Network. University of California, San Francisco.
Potter, M. B., Schafer, S. R., Gonzalez-Mendez, E., Gjeltema, K., Lopez, A., Wu, J., Pedrin, R., Cozen, M., Wilson, R., Thom, D. H., et al. (2001) · PubMed · Cited by 137 · see citing works
A primary care, multi-disciplinary disease management program for opioid-treated patients with chronic non-cancer pain and a high burden of psychiatric comorbidity
Chelminski, P. R., Ives, T. J., Felix, K., Prakken, S., Miller, T. M., Perhac, J. S., Malone, R. M., Bryant, M. E., DeWalt, D. A., & Pignone, M. P. (2005) · BMC Health Services Research · doi:10.1186/1472-6963-5-3 · Cited by 131 · see citing works
A Survey of Chronic Noncancer Pain Patients Prescribed Opioid Analgesics
Cowan, D. T., Wilson‐Barnett, J., Griffiths, P., & Allan, L. G. (2003) · Pain Medicine · doi:10.1111/j.1526-4637.2003.03038.x · Cited by 110 · see citing works
A Pilot Survey of Aberrant Drug-Taking Attitudes and Behaviors in Samples of Cancer and AIDS Patients
Passik, S. D., Kirsh, K. L., McDonald, M. V., Ahn, S. S., Russak, S. M., Martin, L. J., Rosenfeld, B. D., BREITBART, W. S., & Portenoy, R. K. (2000) · Journal of Pain and Symptom Management · doi:10.1016/s0885-3924(00)00119-6 · Cited by 105 · see citing works
What are the qualities of dilemmas experienced when prescribing opioids in general practice?
Bendtsen, P., Hensing, G. K. E., Ebeling, C., & Schedin, A. (1999) · Pain · doi:10.1016/s0304-3959(99)00036-6 · Cited by 89 · see citing works
Concurrent and predictive validity of the Substance Dependence Severity Scale (SDSS)
Miele, G. M., Carpenter, K. M., Cockerham, M. S., Trautman, K. D., BLAINE, J. D., & Hasin, D. S. (2000) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(99)00110-6 · Cited by 88 · see citing works
Comparison of patient self-reports and urinalysis results obtained under naturalistic methadone treatment conditions
Chermack, S. T., Roll, J. M., Reilly, M. P., Davis, L., Kilaru, U., & Grabowski, J. G. (2000) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(99)00106-4 · Cited by 83 · see citing works
Trends in Medical Use and Abuse of Sustained-Release Opioid Analgesics: A Revisit
Novak, S., Nemeth, W. C., & Lawson, K. A. (2004) · Pain Medicine · doi:10.1111/j.1526-4637.2004.04001.x · Cited by 83 · see citing works
Attitudes and knowledge about pain: an assessment of West Virginia family physicians.
Ponte, C. D., & Johnson-Tribino, J. (2005) · PubMed · Cited by 74 · see citing works
Chronic Pain: 1. A New Disease?
Brookoff, D. (2000) · Hospital Practice · doi:10.1080/21548331.2000.11444031 · Cited by 64 · see citing works
Chronic pain management -can we do better? An interview-based survey in primary care
Stannard, C., & Johnson, M. E. (2003) · Current Medical Research and Opinion · doi:10.1185/030079903125002478 · Cited by 62 · see citing works
A Survey of Cancer Pain Management Knowledge and Attitudes of British Columbian Physicians
Gallagher, R. E., Hawley, P. H., & Yeomans, W. (2004) · Pain Research and Management · doi:10.1155/2004/748685 · Cited by 62 · see citing works
Practice guidelines for chronic pain management. A report by the American Society of Anesthesiologists Task Force on Pain Management, Chronic Pain Section.
(1997) · PubMed · Cited by 58 · see citing works
Body image evaluations in women smokers
King, T. K., Matacin, M. L., Marcus, B. H., Bock, B. C., & Tripolone, J. (2000) · Addictive Behaviors · doi:10.1016/s0306-4603(99)00039-8 · Cited by 57 · see citing works
Concordance between verbal report and urine screen of recent marijuana use in adolescents
Akinci, I. H., Tarter, R. E., & Kirisci, L. (2001) · Addictive Behaviors · doi:10.1016/s0306-4603(00)00146-5 · Cited by 57 · see citing works
Assessing aberrant drug-taking behaviors in the patient with chronic pain
Passik, S. D., & Kirsh, K. L. (2004) · Current Pain and Headache Reports · doi:10.1007/s11916-004-0010-3 · Cited by 55 · see citing works
Addiction and Pain
Schnoll, S. H., & Weaver, M. F. (2003) · American Journal on Addictions · doi:10.1080/10550490390210218 · Cited by 47 · see citing works
Are postal questionnaire surveys of reported activity valid? An exploration using general practitioner management of hypertension in older people
Eccles, M., Ford, G. A., Duggan, S., & Steen, N. (1999) · Europe PMC (PubMed Central) · doi:10.25405/ncl.34593567 · Cited by 43 · see citing works
Principles of opioid use in chronic noncancer pain.
Gardner‐Nix, J. (2003) · Europe PMC (PubMed Central) · Cited by 41 · see citing works
Exploring Physicians′ Comfort Level with Opioids for Chronic Noncancer Pain
Scanlon, M. N., & Chugh, U. (2004) · Pain Research and Management · doi:10.1155/2004/290250 · Cited by 40 · see citing works
Pain Clinicians' Rankings of Aberrant Drug-Taking Behaviors
Passik, S. D., Kirsh, K. L., Whitcomb, L., Dickerson, P. K., & Theobald, D. (2002) · Journal of Pain & Palliative Care Pharmacotherapy · doi:10.1080/j354v16n04_04 · Cited by 40 · see citing works
Disease Management for Chronic Pain: Barriers of Program Implementation With Primary Care Physicians
Jamison, R. N., Gintner, L., Rogers, J. F., & Fairchild, D. G. (2002) · Pain Medicine · doi:10.1046/j.1526-4637.2002.02022.x · Cited by 36 · see citing works
Detection of Illicit Opioid and Cocaine Use in Methadone Maintenance Treatment
Wasserman, D. A., Korcha, R. A., Havassy, B. E., & Hall, S. M. (1999) · The American Journal of Drug and Alcohol Abuse · doi:10.1081/ada-100101879 · Cited by 27 · see citing works
Opioids for persistent non-cancer pain: recommendations for clinical practice
Simpson, K. H. (2004) · British Journal of Anaesthesia · doi:10.1093/bja/aeh059 · Cited by 23 · see citing works
Migraine headache
Diamond, S., Freitag, F. G., Solomon, G. D., & Millstein, E. (1987) · Postgraduate Medicine · doi:10.1080/00325481.1987.11699870 · Cited by 12 · see citing works
State Medical Society of Wisconsin statement on the use of opioids for the treatment of chronic pain.
(2001) · PubMed · Cited by 4 · see citing works

Flagged first, then by citations

1 of the 50 references couldn’t be matched to a known paper.

Sorted by citations

CDC Guideline for Prescribing Opioids for Chronic Pain—United States, 2016
Dowell, D., Haegerich, T. M., & Chou, R. (2016) · JAMA · doi:10.1001/jama.2016.1464 · Cited by 5,161 · see citing works
CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016
Dowell, D., Haegerich, T. M., & Chou, R. (2016) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr6501e1 · Cited by 2,697 · see citing works
Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain
Chou, R., Fanciullo, G. J., Fine, P. G., Adler, J. A., Ballantyne, J. C., Davies, P., Donovan, M. I., Fishbain, D. A., Foley, K. M., Fudin, J., et al. (2009) · The Journal of Pain · doi:10.1016/j.jpain.2008.10.008 · Cited by 2,192 · see citing works
The Effectiveness and Risks of Long-Term Opioid Therapy for Chronic Pain: A Systematic Review for a National Institutes of Health Pathways to Prevention Workshop
Chou, R., Turner, J. A., Devine, E. B., Hansen, R. N., Sullivan, S. D., Blazina, I., Dana, T., Bougatsos, C., & Deyo, R. A. (2015) · Annals of Internal Medicine · doi:10.7326/m14-2559 · Cited by 1,606 · see citing works
Opioid Epidemic in the United States
Manchikanti, L. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/es9 · Cited by 1,180 · see citing works
Rates of opioid misuse, abuse, and addiction in chronic pain
Vowles, K. E., McEntee, M. L., Julnes, P. S., Frohe, T. M., Ney, J. P., & van der Goes, D. N. (2015) · Pain · doi:10.1097/01.j.pain.0000460357.01998.f1 · Cited by 1,178 · see citing works
Causes and Consequences of Inadequate Management of Acute Pain
Sinatra, R. S. (2010) · Pain Medicine · doi:10.1111/j.1526-4637.2010.00983.x · Cited by 601 · see citing works
Therapeutic Use, Abuse, and Nonmedical Use of Opioids: A Ten-Year Perspective
Manchikanti, L. (2010) · Pain Physician · doi:10.36076/ppj.2010/13/401 · Cited by 535 · see citing works
CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016
Dowell, D., Haegerich, T. M., & Chou, R. (2016) · MMWR Recommendations and Reports · doi:10.15585/mmwr.rr6501e1er · Cited by 540 · see citing works
Opioids for low back pain
Deyo, R. A., Korff, M. V., & Duhrkoop, D. (2015) · BMJ · doi:10.1136/bmj.g6380 · Cited by 515 · see citing works
Risk Factors for Opioid-Use Disorder and Overdose
Webster, L. R. (2017) · Anesthesia & Analgesia · doi:10.1213/ane.0000000000002496 · Cited by 498 · see citing works
Opioids in the Management of Chronic Non-Cancer Pain: An Update of American Society of the Interventional Pain Physicians’ (ASIPP) Guidelines
Manchikanti, L. (2008) · Pain Physician · doi:10.36076/ppj.2008/11/s5 · Cited by 430 · see citing works
American Society of Interventional Pain Physicians (ASIPP) Guidelines for Responsible Opioid Prescribing in Chronic Non-Cancer Pain: Part 2 - Guidance
ASIPP, A. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/s67 · Cited by 426 · see citing works
Opioids for Chronic Noncancer Pain: Prediction and Identification of Aberrant Drug-Related Behaviors: A Review of the Evidence for an American Pain Society and American Academy of Pain Medicine Clinical Practice Guideline
Chou, R., Fanciullo, G. J., Fine, P. G., Miaskowski, C. A., Passik, S. D., & Portenoy, R. K. (2009) · Journal of Pain · doi:10.1016/j.jpain.2008.10.009 · Cited by 365 · see citing works
Defining racial and ethnic disparities in pain management
Mossey, J. M. (2011) · Clinical Orthopaedics & Related Research · doi:10.1007/s11999-011-1770-9 · Cited by 353 · see citing works
Association between initial opioid prescribing patterns and subsequent long-term use among opioid-naïve patients: a statewide retrospective cohort study
Deyo, R. A., Hallvik, S. E., Hildebran, C., Marino, M., Dexter, E., Irvine, J. M., O’Kane, N., Van Otterloo, J., Wright, D. A., Leichtling, G., et al. (2017) · Journal of General Internal Medicine · doi:10.1007/s11606-016-3810-3 · Cited by 332 · see citing works
Prescription Opioid Abuse in Chronic Pain: A Review of Opioid Abuse Predictors and Strategies to Curb Opioid Abuse
Sehgal, N. (2012) · Pain Physician · doi:10.36076/ppj.2012/15/es67 · Cited by 320 · see citing works
Prescription Opioid Abuse in Chronic Pain: An Updated Review of Opioid Abuse Predictors and Strategies to Curb Opioid Abuse: Part 1
Kaye, A. D. (2017) · Pain Physician · doi:10.36076/ppj.2017.s109 · Cited by 320 · see citing works
Systematic Review: Treatment Agreements and Urine Drug Testing to Reduce Opioid Misuse in Patients With Chronic Pain
Starrels, J. L., Becker, W. C., Alford, D. P., Kapoor, A., Williams, A. R., & Turner, B. J. (2010) · Annals of Internal Medicine · doi:10.7326/0003-4819-152-11-201006010-00004 · Cited by 305 · see citing works
Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews
Els, C., Jackson, T., Kunyk, D., Lappi, V. G., Sonnenberg, B., Hagtvedt, R., Sharma, S., Kolahdooz, F., & Straube, S. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012509.pub2 · Cited by 304 · see citing works
The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review
Nugent, S. M., Morasco, B. J., O'Neil, M. E., Freeman, M., Low, A., Kondo, K., Elven, C., Zakher, B., Motu'apuaka, M., Paynter, R., et al. (2017) · Annals of Internal Medicine · doi:10.7326/m17-0155 · Cited by 301 · see citing works
Long-Term Opioid Therapy Reconsidered
Korff, M. V., Kolodny, A., Deyo, R. A., & Chou, R. (2011) · Annals of Internal Medicine · doi:10.7326/0003-4819-155-5-201109060-00011 · Cited by 261 · see citing works
A Review of Potential Adverse Effects of Long-Term Opioid Therapy
Baldini, A., Korff, M. V., & Lin, E. H. B. (2012) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.11m01326 · Cited by 259 · see citing works
Efficacy of Dronabinol as an Adjuvant Treatment for Chronic Pain Patients on Opioid Therapy
Narang, S., Gibson, D., Wasan, A. D., Ross, E. L., Michna, E., Nedeljkovic, S. S., & Jamison, R. N. (2008) · The Journal of Pain · doi:10.1016/j.jpain.2007.10.018 · Cited by 257 · see citing works
Risks, Management, and Monitoring of Combination Opioid, Benzodiazepines, and/or Alcohol Use
Gudin, J. A., Mogali, S., Jones, J. D., & Comer, S. D. (2013) · Postgraduate Medicine · doi:10.3810/pgm.2013.07.2684 · Cited by 252 · see citing works
American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: Part 2--guidance.
Manchikanti, L., Abdi, S., Atluri, S. L., Balog, C. C., Benyamin, R. M., Boswell, M. V., Brown, K. R., Bruel, B. M., Bryce, D. A., Burks, P. A., et al. (2012) · PubMed · Cited by 243 · see citing works
Risk Factors for Serious Prescription Opioid-Related Toxicity or Overdose among Veterans Health Administration Patients
Zedler, B. K., Xie, L., Wang, L., Joyce, A., Vick, C. C., Kariburyo, F., Rajan, P. K., Başer, O., & Murrelle, L. (2014) · Pain Medicine · doi:10.1111/pme.12480 · Cited by 229 · see citing works
Self-Report of Alcohol Use for Pain in a Multi-Ethnic Community Sample
Riley, J. L., & King, C. (2009) · Journal of Pain · doi:10.1016/j.jpain.2009.03.005 · Cited by 213 · see citing works
Systematic review of prevalence, correlates, and treatment outcomes for chronic non-cancer pain in patients with comorbid substance use disorder
Morasco, B. J., Gritzner, S., Lewis, L., Oldham, R. L., Turk, D. C., & Dobscha, S. K. (2010) · Pain · doi:10.1016/j.pain.2010.10.009 · Cited by 188 · see citing works
The Effectiveness and Risks of Long-Term Opioid Treatment of Chronic Pain
Chou, R., Deyo, R. A., Devine, B., Hansen, R. N., Sullivan, S., Jarvik, J. G., Blazina, I., Dana, T., Bougatsos, C., & Turner, J. E. (2014) · doi:10.23970/ahrqepcerta218 · Cited by 186 · see citing works
Opioid Pharmacotherapy for Chronic Non-Cancer Pain in the United States: A Research Guideline for Developing an Evidence-Base
Chapman, C. R., Lipschitz, D. L., Angst, M. S., Chou, R., Denisco, R. C., Donaldson, G. W., Fine, P. G., Foley, K. M., Gallagher, R. M., Gilson, A. M., et al. (2010) · Journal of Pain · doi:10.1016/j.jpain.2010.02.019 · Cited by 172 · see citing works
Beliefs and attitudes about opioid prescribing and chronic pain management: Survey of primary care providers
Jamison, R. N., Sheehan, K. A., Scanlan, E., Matthews, M. L., & Ross, E. L. (2014) · Journal of Opioid Management · doi:10.5055/jom.2014.0234 · Cited by 172 · see citing works
Time trends and prescribing patterns of opioid drugs in UK primary care patients with non-cancer pain: A retrospective cohort study
Jani, M., Yimer, B. B., Sheppard, T., Lunt, M., & Dixon, W. G. (2020) · PLoS Medicine · doi:10.1371/journal.pmed.1003270 · Cited by 162 · see citing works
Telehealth Versus In-Person Acceptance and Commitment Therapy for Chronic Pain: A Randomized Noninferiority Trial.
Herbert, M. S., Afari, N., Liu, L., Heppner, P., Rutledge, T., Williams, K., Eraly, S., VanBuskirk, K., Nguyen, C., Bondi, M., et al. (2017) · The Journal of Pain · doi:10.1016/j.jpain.2016.10.014 · Cited by 137 · see citing works
Development of a Risk Index for Serious Prescription Opioid-Induced Respiratory Depression or Overdose in Veterans' Health Administration Patients
Zedler, B., Xie, L., Wang, L., Joyce, A., Vick, C., Brigham, J., Kariburyo, F., Baser, O., & Murrelle, L. (2015) · Pain Medicine · doi:10.1111/pme.12777 · Cited by 138 · see citing works
Improving Adherence to Long-term Opioid Therapy Guidelines to Reduce Opioid Misuse in Primary Care
Liebschutz, J. M., Xuan, Z., Shanahan, C. W., Larochelle, M. R., Keosaian, J. E., Beers, D., Guara, G., O’Connor, K., Alford, D. P., Parker, V. A., et al. (2017) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2017.2468 · Cited by 138 · see citing works
Opioid use behaviors, mental health and pain—Development of a typology of chronic pain patients
Banta‐Green, C. J., Merrill, J. O., Doyle, S. R., Boudreau, D. M., & Calsyn, D. A. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.03.021 · Cited by 137 · see citing works
Trends in prescribed opioid therapy for non-cancer pain for individuals with prior substance use disorders
Weisner, C. M., Campbell, C. I., Ray, T. G., Saunders, K. W., Merrill, J. O., Banta‐Green, C. J., Sullivan, M. D., Silverberg, M. J., Mertens, J. R., Boudreau, D. M., et al. (2009) · Pain · doi:10.1016/j.pain.2009.05.006 · Cited by 137 · see citing works
Gender Differences in Risk Factors for Aberrant Prescription Opioid Use
Jamison, R. N., Butler, S. F., Budman, S. H., Edwards, R. R., & Wasan, A. D. (2009) · Journal of Pain · doi:10.1016/j.jpain.2009.07.016 · Cited by 132 · see citing works
American Society of Interventional Pain Physicians (ASIPP) guidelines for responsible opioid prescribing in chronic non-cancer pain: Part I--evidence assessment.
Manchikanti, L., Abdi, S., Atluri, S. L., Balog, C. C., Benyamin, R. M., Boswell, M. V., Brown, K. R., Bruel, B. M., Bryce, D. A., Burks, P. A., et al. (2012) · PubMed · Cited by 129 · see citing works
Racial Differences in Primary Care Opioid Risk Reduction Strategies
Becker, W. C., Starrels, J. L., Heo, M., Li, X., Weiner, M. G., & Turner, B. J. (2011) · The Annals of Family Medicine · doi:10.1370/afm.1242 · Cited by 125 · see citing works
Low Use of Opioid Risk Reduction Strategies in Primary Care Even for High Risk Patients with Chronic Pain
Starrels, J. L., Becker, W. C., Weiner, M. G., Li, X., Heo, M., & Turner, B. J. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1648-2 · Cited by 123 · see citing works
Opioids, Chronic Pain, and Addiction in Primary Care
Barry, D. T., Irwin, K. S., Jones, E. S., Becker, W. C., Tetrault, J. M., Sullivan, L. E., Hansen, H., O’Connor, P. G., Schottenfeld, R. S., & Fiellin, D. A. (2010) · Journal of Pain · doi:10.1016/j.jpain.2010.04.002 · Cited by 122 · see citing works
Opioid misuse in gastroenterology and non-opioid management of abdominal pain
Szigethy, E., Knisely, M., & Drossman, D. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2017.141 · Cited by 117 · see citing works
Long-term opioid treatment of chronic nonmalignant pain: unproven efficacy and neglected safety?
Kissin, I. (2013) · Journal of Pain Research · doi:10.2147/jpr.s47182 · Cited by 117 · see citing works
Concurrent Use of Alcohol and Sedatives Among Persons Prescribed Chronic Opioid Therapy: Prevalence and Risk Factors
Saunders, K. W., Korff, M. V., Campbell, C. I., Banta‐Green, C. J., Sullivan, M. D., Merrill, J. O., & Weisner, C. M. (2012) · Journal of Pain · doi:10.1016/j.jpain.2011.11.004 · Cited by 114 · see citing works
Prescription medication misuse and substance use disorder in VA primary care patients with chronic pain
Morasco, B. J., & Dobscha, S. K. (2008) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2007.12.004 · Cited by 116 · see citing works
Biopsychosocial Approach to Assessing and Managing Patients with Chronic Pain
Cheatle, M. D. (2015) · Medical Clinics of North America · doi:10.1016/j.mcna.2015.08.007 · Cited by 115 · see citing works
Using natural language processing to identify problem usage of prescription opioids
Carrell, D., Cronkite, D., Palmer, R. E., Saunders, K. W., Gross, D. E., Masters, E. T., Hylan, T. R., & Korff, M. V. (2015) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2015.09.002 · Cited by 114 · see citing works
Prescription Opioids, Overdose Deaths, and Physician Responsibility
McLellan, A. T. (2008) · JAMA · doi:10.1001/jama.2008.793 · Cited by 112 · see citing works
Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients
Wasan, A. D., Butler, S. F., Budman, S. H., Fernandez, K., Weiss, R. D., Greenfield, S. F., & Jamison, R. N. (2009) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e318193a6c4 · Cited by 109 · see citing works
Clinical Factors Associated With Prescription Drug Use Disorder in Urban Primary Care Patients with Chronic Pain
Liebschutz, J. M., Saitz, R., Weiss, R. D., Averbuch, T., Schwartz, S., Meltzer, E. C., Claggett-Borne, E., Cabral, H., & Samet, J. H. (2010) · Journal of Pain · doi:10.1016/j.jpain.2009.10.012 · Cited by 109 · see citing works
Prevalence and treatment of opioid use disorders among primary care patients in six health systems
Lapham, G. T., Boudreau, D. M., Johnson, E. A., Bobb, J. F., Matthews, A. G., McCormack, J., Liu, D., Samet, J. H., Saxon, A. J., Campbell, C. I., et al. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107732 · Cited by 106 · see citing works
Opioid use disorder and treatment: challenges and opportunities
Hoffman, K. A., Terashima, J. P., & McCarty, D. W. (2019) · BMC Health Services Research · doi:10.1186/s12913-019-4751-4 · Cited by 104 · see citing works
Pain, physical dependence and pseudoaddiction: Redefining addiction for ‘nice’ people?
Bell, K., & Salmon, A. (2008) · International Journal of Drug Policy · doi:10.1016/j.drugpo.2008.06.002 · Cited by 104 · see citing works
Prescribed Opioid Difficulties, Depression, and Opioid Dose Among Chronic Opioid Therapy Patients
Merrill, J., Korff, M. V., Banta-Green, C. J., Sullivan, M., Saunders, K. W., Campbell, C. I., & Weisner, C. (2012) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2012.06.018 · Cited by 103 · see citing works
Advanced Urine Toxicology Testing
Tenore, P. L. (2010) · Journal of Addictive Diseases · doi:10.1080/10550887.2010.509277 · Cited by 101 · see citing works
Brief Alcohol Intervention in the Emergency Department: Moderators of Effectiveness
Walton, M. A., Goldstein, A. L., Chermack, S. T., McCammon, R. J., Cunningham, R. M., Barry, K. L., & Blow, F. C. (2008) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2008.69.550 · Cited by 96 · see citing works
2017 HIVMA of IDSA Clinical Practice Guideline for the Management of Chronic Pain in Patients Living With HIV
Bruce, R. D., Merlin, J. S., Lum, P. J., Ahmed, E., Alexander, C. S., Corbett, A., Foley, K. M., Leonard, K., Treisman, G. J., & Selwyn, P. A. (2017) · Clinical Infectious Diseases · doi:10.1093/cid/cix636 · Cited by 93 · see citing works
Obstructive Sleep Apnea and Chronic Opioid Use
Guilleminault, C., Cao, M. T., Yue, H. J., & Chawla, P. (2010) · Lung · doi:10.1007/s00408-010-9254-3 · Cited by 93 · see citing works
Chronic Pain and Risk Factors for Opioid Misuse in a Palliative Care Clinic
Childers, J. W., King, L. A., & Arnold, R. M. (2014) · American Journal of Hospice and Palliative Medicine® · doi:10.1177/1049909114531445 · Cited by 92 · see citing works
The Burden of the Nonmedical Use of Prescription Opioid Analgesics
Gilson, A. M., & Kreis, P. G. (2009) · Pain Medicine · doi:10.1111/j.1526-4637.2009.00668.x · Cited by 84 · see citing works
Nonmedical Prescription Opioid Use and Mental Health and Pain Comorbidities: A Narrative Review
Amari, E., Rehm, J. T., Goldner, E. M., & Fischer, B. (2011) · The Canadian Journal of Psychiatry · doi:10.1177/070674371105600808 · Cited by 82 · see citing works
The Prescribed Opioids Difficulties Scale
Banta-Green, C. J., Korff, M. V., Sullivan, M. D., Merrill, J., Doyle, S. R., & Saunders, K. W. (2010) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e3181e103d9 · Cited by 71 · see citing works
Medical Misuse of Controlled Medications Among Adolescents
McCabe, S. E. (2011) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpediatrics.2011.114 · Cited by 80 · see citing works
Chronic pain treatment with opioid analgesics: benefits versus harms of long-term therapy
Sehgal, N., Colson, J., & Smith, H. S. (2013) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2013.846517 · Cited by 79 · see citing works
Adherence to Clinical Guidelines for Opioid Therapy for Chronic Pain in Patients with Substance Use Disorder
Morasco, B. J., Duckart, J. P., & Dobscha, S. K. (2011) · Journal of General Internal Medicine · doi:10.1007/s11606-011-1734-5 · Cited by 79 · see citing works
Recommendations for Urine Drug Monitoring as a Component of Opioid Therapy in the Treatment of Chronic Pain
Peppin, J. F., Passik, S. D., Couto, J. E., Fine, P. G., Christo, P. J., Argoff, C. E., Aronoff, G. M., Bennett, D. S., Cheatle, M. D., Slevin, K. A., et al. (2012) · Pain Medicine · doi:10.1111/j.1526-4637.2012.01414.x · Cited by 74 · see citing works
Predictors of Long-Term Opioid Use Among Patients With Painful Lumbar Spine Conditions
Krebs, E. E., Lurie, J. D., Fanciullo, G. J., Tosteson, T. D., Blood, E., Carey, T. S., & Weinstein, J. N. (2009) · Journal of Pain · doi:10.1016/j.jpain.2009.05.007 · Cited by 70 · see citing works
Moving opioid misuse prevention upstream: A pilot study of community pharmacists screening for opioid misuse risk
Strand, M. A., Eukel, H. N., & Burck, S. (2018) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2018.07.011 · Cited by 68 · see citing works
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients
Fleming, M., Davis, J., & Passik, S. (2008) · Pain medicine (Malden, Mass.) · doi:10.1111/j.1526-4637.2008.00491.x · Cited by 79 · see citing works
Self-citation
The Prevalence and Significance of Cannabis Use in Patients Prescribed Chronic Opioid Therapy: A Review of the Extant Literature
Reisfield, G. M., Wasan, A. D., & Jamison, R. N. (2009) · Pain Medicine · doi:10.1111/j.1526-4637.2009.00726.x · Cited by 67 · see citing works
High Rates of Inappropriate Drug Use in the Chronic Pain Population
Couto, J. E., Romney, M., Leider, H. L., Sharma, S., & Goldfarb, N. I. (2009) · Population Health Management · doi:10.1089/pop.2009.0015 · Cited by 66 · see citing works
Nonmedical Use of Prescription Opioids: Motive and Ubiquity Issues
Zacny, J. P., & Lichtor, S. A. (2008) · Journal of Pain · doi:10.1016/j.jpain.2007.12.008 · Cited by 63 · see citing works
The prevalence of problem opioid use in patients receiving chronic opioid therapy
Palmer, R. E., Carrell, D., Cronkite, D., Saunders, K. W., Gross, D. E., Masters, E. T., Donevan, S. D., Hylan, T. R., & Kroff, M. V. (2015) · Pain · doi:10.1097/j.pain.0000000000000145 · Cited by 62 · see citing works
Interpretation of Urine Drug Testing in Pain Patients
Pesce, A. J., West, C., City, K. E., & Strickland, J. (2012) · Pain Medicine · doi:10.1111/j.1526-4637.2012.01350.x · Cited by 62 · see citing works
Long-term use of opioids for complex chronic pain
Korff, M. R. V. (2013) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2013.09.011 · Cited by 62 · see citing works
Documented opioid use disorder and its treatment in primary care patients across six U.S. health systems
Boudreau, D. M., Lapham, G. T., Johnson, E. A., Bobb, J. F., Matthews, A. G., McCormack, J., Liu, D. S., Campbell, C. I., Rossom, R. C., Binswanger, I. A., et al. (2020) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2020.02.001 · Cited by 61 · see citing works
Simultaneous Quantitation of 78 Drugs and Metabolites in Urine with a Dilute-And-Shoot LC–MS-MS Assay
Cao, Z., Kaleta, E. J., & Wang, P. (2015) · Journal of Analytical Toxicology · doi:10.1093/jat/bkv024 · Cited by 60 · see citing works
The Role of Urine Drug Testing for Patients on Opioid Therapy
Pergolizzi, J. V., Pappagallo, M., Stauffer, J. W., Gharibo, C. G., Fortner, N. A., Jesus, M. N. D., Brennan, M. J., Richmond, C., Hussey, D., & The Integrated Drug Compliance Study Group (IDCSG) (2010) · Pain Practice · doi:10.1111/j.1533-2500.2010.00375.x · Cited by 59 · see citing works
Attitudes of Primary Care Practitioners in Managing Chronic Pain Patients Prescribed Opioids for Pain: A Prospective Longitudinal Controlled Trial.
Jamison, R., Scanlan, E., Matthews, M. L., Jurcik, D., & Ross, E. (2015) · Pain medicine (Malden, Mass.) · doi:10.1111/pme.12871 · Cited by 58 · see citing works
Chronic Non-Cancer Pain: A Siren for Primary Care - A Report From the PRImary care MultiEthnic Network (PRIME Net)
Leverence, R. R., Williams, R. L., Potter, M. B., Fernald, D. H., Unverzagt, M., Pace, W. D., Parnes, B. L., Daniels, E., SKIPPER, B. J., Volk, R. J., et al. (2011) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2011.05.110030 · Cited by 57 · see citing works
Prescription opioid abuse: challenges and opportunities for payers.
Katz, N. P., Birnbaum, H. G., Brennan, M. J., Freedman, J. D., Gilmore, G. P., Jay, D. W., Kenna, G. A., Madras, B. K., McElhaney, L., Weiss, R. D., et al. (2013) · PubMed · Cited by 57 · see citing works
Self-reports of medication side effects and pain-related activity interference in patients with chronic pain
Martel, M. O., Finan, P. H., Dolman, A. J., Subramanian, S. V., Edwards, R. R., Wasan, A. D., & Jamison, R. N. (2015) · Pain · doi:10.1097/j.pain.0000000000000154 · Cited by 55 · see citing works
Racial disparities in pain management in primary care
Ezenwa, M. O., & Fleming, M. (2012) · Journal of Pain · doi:10.1016/j.jpain.2012.01.088 · Cited by 55 · see citing works
Self-citation
A Conceptual Framework for Understanding Unintended Prolonged Opioid Use
Hooten, W. M., Brummett, C. M., Sullivan, M. D., Goesling, J., Tilburt, J. C., Merlin, J. S., Sauver, J. L. S., Wasan, A. D., Clauw, D. J., & Warner, D. O. (2017) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2017.10.010 · Cited by 55 · see citing works
The Risks of Opioid Treatment: Perspectives of Primary Care Practitioners and Patients from Safety-Net Clinics
Hurstak, E., Kushel, M., Chang, J. S., Ceasar, R. C., Zamora, K. A., Miaskowski, C. A., & Knight, K. R. (2017) · Substance Abuse · doi:10.1080/08897077.2017.1296524 · Cited by 54 · see citing works
Association Between Substance Use Disorder Status and Pain-Related Function Following 12 Months of Treatment in Primary Care Patients With Musculoskeletal Pain
Morasco, B. J., Corson, K., Turk, D. C., & Dobscha, S. K. (2010) · Journal of Pain · doi:10.1016/j.jpain.2010.07.010 · Cited by 53 · see citing works
Opioids in chronic noncancer pain
Manchikanti, L., Benyamin, R. M., Datta, S., Vallejo, R., & Smith, H. S. (2010) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.37 · Cited by 53 · see citing works
Understanding Fibromyalgia and Its Related Disorders
(2008) · The Primary Care Companion to The Journal of Clinical Psychiatry · doi:10.4088/pcc.v10n0208 · Cited by 50 · see citing works
Preliminary evaluation of the efficacy, safety, and costs associated with the treatment of chronic pain with medical cannabis
Bellnier, T., Brown, G. W., & Ortega, T. R. (2018) · Mental Health Clinician · doi:10.9740/mhc.2018.05.110 · Cited by 48 · see citing works
Measures Such As Interstate Cooperation Would Improve The Efficacy Of Programs To Track Controlled Drug Prescriptions
Deyo, R. A., Irvine, J. M., Millet, L. M., Beran, T., O’Kane, N., Wright, D. A., & McCarty, D. W. (2013) · Health Affairs · doi:10.1377/hlthaff.2012.0945 · Cited by 48 · see citing works
Narcotic Bowel Syndrome and Opioid-Induced Constipation
Szigethy, E., Schwartz, M. B., & Drossman, D. A. (2014) · Current Gastroenterology Reports · doi:10.1007/s11894-014-0410-4 · Cited by 45 · see citing works
To what extent does a cohort of new users of weak opioids develop persistent or probable problematic opioid use?
Skurtveit, S. O., Furu, K., Borchgrevink, P. C., Handal, M., & Fredheim, O. M. S. (2011) · Pain · doi:10.1016/j.pain.2011.02.045 · Cited by 45 · see citing works
Alcohol and Opioid Use in Chronic Pain: A Cross-Sectional Examination of Differences in Functioning Based on Misuse Status
Vowles, K. E., Witkiewitz, K. A., Pielech, M., Edwards, K. A., McEntee, M. L., Bailey, R. W., Bolling, L. A., & Sullivan, M. D. (2018) · Journal of Pain · doi:10.1016/j.jpain.2018.04.013 · Cited by 43 · see citing works
Prevalence and Trends of Concurrent Opioid Analgesic and Benzodiazepine Use Among Veterans Affairs Patients with Post-traumatic Stress Disorder, 2003–2011
Hawkins, E. J., Malte, C. A., Grossbard, J. R., & Saxon, A. J. (2015) · Pain Medicine · doi:10.1111/pme.12787 · Cited by 43 · see citing works
Substance-related disorders: A review of prevalence and correlates among patients with chronic pain
Martel, M. O., Shir, Y., & Ware, M. A. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.032 · Cited by 41 · see citing works
Increasing Frequency of Opioid Prescriptions for Chronic Abdominal Pain in US Outpatient Clinics
Dorn, S. D., Meek, P. D., & Shah, N. D. (2011) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2011.08.008 · Cited by 42 · see citing works
Measurement of opioid problems among chronic pain patients in a general medical population
Banta‐Green, C. J., Merrill, J. O., Doyle, S. R., Boudreau, D. M., & Calsyn, D. A. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.03.022 · Cited by 40 · see citing works
Does Opioid Pain Medication Use Affect the Outcome of Patients With Lumbar Disc Herniation?
Radcliff, K. E., Freedman, M. K., Hilibrand, A. S., Isaac, R., Lurie, J. D., Zhao, W., Vaccaro, A. R., Albert, T. J., & Weinstein, J. N. (2013) · Spine · doi:10.1097/brs.0b013e3182959e4e · Cited by 40 · see citing works

Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients
Fleming, M., Davis, J., & Passik, S. (2008) · Pain medicine (Malden, Mass.) · doi:10.1111/j.1526-4637.2008.00491.x · Cited by 79 · see citing works
Self-citation
The Prevalence and Significance of Cannabis Use in Patients Prescribed Chronic Opioid Therapy: A Review of the Extant Literature
Reisfield, G. M., Wasan, A. D., & Jamison, R. N. (2009) · Pain Medicine · doi:10.1111/j.1526-4637.2009.00726.x · Cited by 67 · see citing works
Aberrant behaviors in a primary care-based cohort of patients with chronic pain identified as misusing prescription opioids
Cheatle, M. D., O’Brien, C. P., Mathai, K. M., Matthew Hansen, M., Grasso, M., & Yi, P. (2013) · Journal of Opioid Management · doi:10.5055/jom.2013.0174 · Cited by 22 · see citing works
Prescription opioid abuse, addiction and psychopathology in a pain clinic
López-Lazcano, A., Ortega, L., Faulí, A., Busquets, C., & Lligoña, A. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2017.01.1744 · Cited by 1 · see citing works
(445) Chronic opioid therapy urine drug testing in primary care: rates and predictors of aberrant results
Turner, J., Saunders, K. W., Shortreed, S. M., LeResche, L., & Korff, M. V. (2014) · Journal of Pain · doi:10.1016/j.jpain.2014.01.356

Authors: Fleming, M. F., Balousek, S. L., Klessig, C. L., Mundt, M. P., & Brown, D. D.
Affiliations: University of Wisconsin–Madison (US)
University of British Columbia (CA)
Corresponding author: Fleming, Michael F.
ORCID: Fleming, Michael F.
Mundt, Marlon P.
Venue: The Journal of Pain
Publisher: Elsevier BV
Published: 2007-07
Volume: 8
Issue: 7
Pages: 573-582
ISSN: 1526-5900 (ISSN-L)
DOI: 10.1016/j.jpain.2007.02.432
PMC: PMC1959336
OpenAlex: W2010125810
Cited by: 274
References: 50
Citations by year: 2026: 1 · 2025: 1 · 2024: 3 · 2023: 8 · 2022: 8 · 2021: 10 · 2020: 13 · 2019: 16 · 2018: 14 · 2017: 22 · 2016: 15 · 2015: 17 · 2014: 19 · 2013: 19 · 2012: 20
FWCI: 22.05
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5916 d)
Locations: Journal of Pain (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: National Institute on Alcohol Abuse and Alcoholism (T32AA014845)
National Institute on Drug Abuse (R01DA013686)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords: opioid use disorder, substance use disorders, primary care, cocaine use, cannabis use, psychiatric comorbidity, chronic pain
MeSH terms: Adolescent, Adult, Aged, Aged, 80 and over, Analgesics, Opioid, Marijuana Abuse, Chronic Disease, Drug Administration Schedule, Humans, Mass Screening, Middle Aged, Opioid-Related Disorders, Pain, Intractable, Intractable Pain, Physicians, Family, Risk Factors, Comorbidity, Causality, Prevalence, Logistic Models, Urinalysis, Substance-Related Disorders, Cocaine-Related Disorders

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Substance Use Disorders in a Primary Care Sample Receiving Daily Opioid Therapy

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks