The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.
An overview of the relationship between oxidative stress and chemical carcinogenesis
Open accessAbstract
Substantial experimental evidence exists which implicates both oxygen- and organic-free radical intermediates in the multiple stages of chemical carcinogenesis. This overview summarizes some of the biochemical and molecular interactions which could result from a state of oxidative stress following the generation of free radical intermediates from chemical carcinogens in target cells. Evidence for a relationship between carcinogenesis and inflammation as a mediator of oxidative stress is also discussed. Understanding the interactions of radical intermediates with target biomolecules should lead to the development of relevant biomarkers of these interactions as well as rational chemoprotective strategies with antioxidants or other radical detoxifiers for the prevention of neoplasia.
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Citations
Cites
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Sies, H. (1997) · Experimental Physiology · doi:10.1113/expphysiol.1997.sp004024 · Cited by 4,566
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Cited by
Free radicals, metals and antioxidants in oxidative stress-induced cancer
Valko, M., Rhodes, C. J., Moncol, J., Izakovic, M., & Mazur, M. (2006) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2005.12.009 · Cited by 6,680
Oxidative stress, inflammation, and cancer: How are they linked?
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.09.006 · Cited by 5,441
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The Role of Oxidative Stress in Carcinogenesis
Klaunig, J. E., & Kamendulis, L. M. (2004) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.44.101802.121851 · Cited by 1,533
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Metadata
- Authors
- Trush, M. A., & Kensler, T. W.
- Venue
- Free Radical Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 1991
- Volume
- 10
- Issue
- 3-4
- Pages
- 201-209
- ISSN
- 0891-5849 (ISSN-L)
- OpenAlex
- W1985394365
- Cited by
- 372
- References
- 58
- FWCI
- 5.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Trush, M. A., & Kensler, T. W. (1991). An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Radical Biology and Medicine. https://doi.org/10.1016/0891-5849(91)90077-g
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
