Schizophrenia and rheumatoid arthritis: a review
Open accessAbstract
Fourteen epidemiologic studies of the relationship of rheumatoid arthritis to schizophrenia have been conducted between 1934 and 1985. Twelve of the studies report a lower-than-expected rate of rheumatoid arthritis in populations of schizophrenics. Methodologic weaknesses in the studies are assessed. Nutritional, hormonal, psychosocial, genetic, and immunologic data and theories are briefly reviewed which might explain the epidemiologic results. There is sufficient evidence for the negative association between the two disorders to justify further research.
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Rheumatoid arthritis has a negative correlation with schizophrenia.
“Rheumatoid arthritis in particular has been shown to have a negative correlation with schizophrenia (Eaton et al. 1992(Eaton et al. , 2006;;Oken & Schulzer 1999).”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Eaton et al. 1992
A consistent finding is a negative relationship between schizophrenia and autoimmune diseases.
“A consistent finding is the negative relationship between schizophrenia and autoimmune diseases.”
From Excess early mortality in schizophrenia. (2014) · cites this paper as Eaton et al. 1992
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- Authors
- Eaton, W. W., Hayward, C., & Ram, R.
- Affiliations
- Johns Hopkins University (US)
- Stanford University (US)
- State University of New York (US)
- Corresponding author
- Eaton, William W
- ORCID
- Eaton, William W
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 1992-03
- Volume
- 6
- Issue
- 3
- Pages
- 181-192
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W1990840023
- Cited by
- 172
- References
- 120
- Citations by year
- 2024: 3 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 5 · 2019: 5 · 2018: 4 · 2017: 6 · 2016: 4 · 2015: 7 · 2014: 5 · 2013: 8 · 2012: 3
- FWCI
- 0.69
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Schizophrenia Research (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (44653, 44801)
- National Institute of Mental Health
- Topics
- Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic Associations and Epidemiology
- Keywords
- schizophrenia, rheumatoid arthritis
- MeSH terms
- Arthritis, Rheumatoid, Cross-Sectional Studies, Humans, Risk Factors, Schizophrenia, Schizophrenic Psychology, United States, Comorbidity, Incidence
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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