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Cited by 173Bone Metabolism and DiseasesBone health and osteoporosis researchThyroid Disorders and Treatments

The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.

Trabecular bone remodeling and bone balance in hyperthyroidism

Eriksen, E.F., Mosekilde, L., Melsen, F.·1985·Bone
DOI 10.1016/8756-3282(85)90218-2
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Abstract

In vivo tetracycline double-labeled iliac crest bone biopsies from 15 hyperthyroid patients were used for the reconstruction of curves describing the variation of resorption depth and formation thickness with time. The curves emerging were compared to curves reconstructed from 13 age- and sex-matched normal individuals (mean age 44 years). The median function period for resorptive cells in hyperthyroid patients (16 days) was about one-third the resorptive period in normals (51 days). No significant difference between the osteoclast-, mononuclear-, or preosteoblast-like cell resorption depths could be demonstrated between the two groups. Consequently, the median resorption rate in hyperthyroid patients (3.8 microns/day) was more than 3 times higher than the value in the control group (1.1 micron/day). Median Sigma, was shorter in the hyperthyroid group (109 days) than in the control group (151 days, P less than 0.05), as was the median initial mineralization lag time (5 and 16 days, respectively, P less than 0.01). No significant difference between the measured mean completed wall thickness (mcwT) values in the hyperthyroid groups and the control group could be demonstrated (58.1 and 60.5 micron respectively). Median initial mineralization rate in the hyperthyroid group (1.2 micron3/micron2 per day) was not significantly higher than the value calculated in the control group (0.9 micron3/micron2 per day), but median initial matrix appositional rate in hyperthyroid (4.8 microns3/micron2 per day) was 3 times higher than the value calculated for normals (1.6 micron3/micron2 per day) (P less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Overview

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Registry

Crossref · 10.1016/8756-3282(85)90218-2

Cites

17 of 17 references verified0 citation errors · 0 not checkable

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Citations

Cites

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Research works printed but not linked: 1

  1. Parfitt, 1980, Kinetics of matrix and mineral apposition in osteoporosis and renal osteodystrophy. Relationship to rate of turnover and cell morphology, Metab. Bone Dis. Rel. Res., 2S, 213

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Metadata

Authors
Eriksen, E. F., Mosekilde, L., & Melsen, F.
Corresponding author
Eriksen, E.F.
ORCID
Venue
Bone
Publisher
Elsevier BV
Published
1985-01
Volume
6
Issue
6
Pages
421-428
ISSN
  • 1873-2763 (ISSN-L)
  • 8756-3282
DOI
10.1016/8756-3282(85)90218-2
OpenAlex
W2051022943
Cited by
172
References
17
Citations by year
2026: 2 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 2 · 2020: 6 · 2019: 2 · 2018: 6 · 2017: 3 · 2016: 5 · 2015: 4 · 2014: 4 · 2013: 2 · 2012: 3
FWCI
1.18
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Bone (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Keywords
hyperthyroidism, trabecular bone remodeling, bone balance, tetracycline double labeling, iliac crest bone biopsy, bone resorption rate, bone formation rate, formation thickness, mineralization lag time, osteoclasts, bone turnover markers
MeSH terms
Adult, Aged, Bone Matrix, Bone Resorption, Female, Humans, Hyperthyroidism, Male, Middle Aged, Minerals, Osteogenesis, Regression Analysis, Time Factors

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