The Metabolic Influence of Progestins
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Progesterone exerts influence over protein metabolism, specifically during the luteal phase, corresponding with increases in protein oxidation at rest and during exercise at this time in the menstrual cycle.
“Progesterone also exerts influence over protein metabolism, specifically during the luteal phase, which corresponds with the previously observed increases in protein oxidation at rest and during exercise at this time in the menstrual cycle [81,164].”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [164]
In eumenorrheic women, protein catabolism is higher at rest and following aerobic endurance exercise in the luteal phase, when estrogen and progesterone are elevated, compared to the early follicular phase when estrogen and progesterone concentrations are low.
“In eumenorrheic women, evidence suggests protein catabolism is higher at rest and following aerobic endurance exercise in the luteal phase, when estrogen and progesterone are elevated, compared to the early follicular phase when estrogen and progesterone concentrations are low [81,164,223,224].”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [164]
Protein oxidation during exercise appears to be greater during the mid-luteal phase.
“protein oxidation during exercise appears to be greater during the mid-luteal phase [164,223]”
From International society of sports nutrition position stand: nutritional concerns of the female athlete (2023) · cites this paper as [164]
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Metabolic effects of progesterone
Kalkhoff, R. K. (1982) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(16)32480-2 · Cited by 153 · see citing works
Effect of oral contraceptives on the renin angiotensin system and renal function
Kang, A. K., Duncan, J. A., Cattran, D. C., Floras, J. S., Lai, V., Scholey, J. W., & Miller, J. A. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.3.r807 · Cited by 103 · see citing works
International society of sports nutrition position stand: nutritional concerns of the female athlete
Sims, S. T., Kerksick, C. M., Smith-Ryan, A. E., Janse de Jonge, X. A. K., Hirsch, K. R., Arent, S. M., Hewlings, S. J., Kleiner, S. M., Bustillo, E., Tartar, J. L., et al. (2023) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2023.2204066 · Cited by 91 · see citing works
“amino acid concentrations and increasing total urinary nitrogen excretion (without aminoaciduria) [157,165] due to increased protein biosynthesis of the endometrial lining.”
Background
- Authors
- Landau, R. L., & Poulos, J. T.
- Affiliations
- University of Chicago (US)
- Venue
- Advances in Metabolic Disorders
- Publisher
- Elsevier
- Published
- 1971
- Volume
- 5
- Pages
- 119-147
- ISSN
- 0065-2903 (ISSN-L)
- OpenAlex
- W1859520468
- Cited by
- 21
- References
- 107
- Citations by year
- 2025: 1 · 2023: 2 · 2021: 1 · 2019: 1 · 2014: 1 · 2012: 1
- FWCI
- 0.00
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Advances in metabolic disorders (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal Regulation and Hypertension
- Keywords
- progesterone, synthetic progestins, protein metabolism, electrolyte metabolism, carbohydrate metabolism, fat metabolism, glucocorticoid biosynthesis, androgen production, estrogen synthesis, cholesterol, sodium excretion, oral contraceptives, adverse effects, growth-promoting effect, estrogen priming
- MeSH terms
- Aldosterone, Amino Acids, Carbon Dioxide, Clinical Trials as Topic, Contraceptives, Oral, Coronary Disease, Diabetes Mellitus, Electrolytes, Female, Glucose Tolerance Test, Humans, Hydroxyprogesterones, Male, Medroxyprogesterone, Mineralocorticoids, Natriuresis, Nitrogen, Potassium, Pregnancy, Pregnanediol, Progestins, Proteins, Respiration, Respiratory Center, Growth Hormone, Anabolic Agents, Lipid Metabolism
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