CoChat
Sign Up
Cited by 24Zebrafish Biomedical Research ApplicationsNeural dynamics and brain functionNeurogenesis and neuroplasticity mechanisms

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

Development of motor rhythms in zebrafish embryos

Saint-Amant, Louis·2010·Progress in Brain Research
DOI 10.1016/b978-0-444-53613-6.00004-6
Open this paper in CoChat — free account

Abstract

The nervous system can generate rhythms of various frequencies; on the low-frequency side, we have the circuits regulating circadian rhythms with a 24-h period, while on the high-frequency side we have the motor circuits that underlie flight in a hummingbird. Given the ubiquitous nature of rhythms, it is surprising that we know very little of the cellular and molecular mechanisms that produce them in the embryos and of their potential role during the development of neuronal circuits. Recently, zebrafish has been developed as a vertebrate model to study the genetics of neural development. Zebrafish offer several advantages to the study of nervous system development including optical and electrophysiological analysis of neuronal activity even at the earliest embryonic stages. This unique combination of physiology and genetics in the same animal model has led to insights into the development of neuronal networks. This chapter reviews work on the development of zebrafish motor rhythms and speculates on birth and maturation of the circuits that produce them.

Overview

Integrity signals

Registry

Crossref · 10.1016/b978-0-444-53613-6.00004-6

Cites

6 of 6 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 6 references

Research works printed but not linked: 111

  1. Balciunas, 2004, Enhancer trapping in zebrafish using the Sleeping Beauty transposon, BMC Genomics, 5, 62, 10.1186/1471-2164-5-62 · DOI
  2. Bate, 1999, Development of motor behaviour, Current Opinion in Neurobiology, 9, 670, 10.1016/S0959-4388(99)00031-8 · DOI
  3. Behra, 2002, Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo, Nature Neuroscience, 5, 111, 10.1038/nn788 · DOI
  4. Bernhardt, 1990, Identification of spinal neurons in the embryonic and larval zebrafish, The Journal of Comparative Neurology, 302, 603, 10.1002/cne.903020315 · DOI · Paper page
  5. Birely, 2005, Genetic screens for genes controlling motor nerve-muscle development and interactions, Developmental Biology, 280, 162, 10.1016/j.ydbio.2005.01.012 · DOI
  6. Brustein, 2003, Steps during the development of the zebrafish locomotor network, Journal of Physiology, Paris, 97, 77, 10.1016/j.jphysparis.2003.10.009 · DOI
  7. Burgess, 2009, Unidirectional startle responses and disrupted left-right co-ordination of motor behaviors in robo3 mutant zebrafish, Genes, Brain, and Behavior, 8, 500, 10.1111/j.1601-183X.2009.00499.x · DOI
  8. Buss, 2003, Membrane properties related to the firing behavior of zebrafish motoneurons, Journal of Neurophysiology, 89, 657, 10.1152/jn.00324.2002 · DOI
  9. Buss, 2001, Synaptic drive to motoneurons during fictive swimming in the developing zebrafish, Journal of Neurophysiology, 86, 197, 10.1152/jn.2001.86.1.197 · DOI · Paper page
  10. Buss, 2002, Activation of embryonic red and white muscle fibers during fictive swimming in the developing zebrafish, Journal of Neurophysiology, 87, 1244, 10.1152/jn.00659.2001 · DOI
  11. Chong, 2007, Interaction between hindbrain and spinal networks during the development of locomotion in zebrafish, Developmental Neurobiology, 67, 933, 10.1002/dneu.20398 · DOI
  12. Corner, 1978, Spontaneous motor rhythms in early life—phenomenological and neurophysiological aspects, Progress in Brain Research, 48, 349, 10.1016/S0079-6123(08)61034-1 · DOI
  13. Crill, 1996, Persistent sodium current in mammalian central neurons, Annual Review of Physiology, 58, 349, 10.1146/annurev.ph.58.030196.002025 · DOI
  14. Cui, 2005, The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS, The Journal of Neuroscience, 25, 6610, 10.1523/JNEUROSCI.5009-04.2005 · DOI
  15. Cui, 2004, shocked Gene is required for the function of a premotor network in the zebrafish CNS, Journal of Neurophysiology, 92, 2898, 10.1152/jn.00419.2004 · DOI
  16. Douglass, 2008, Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons, Current Biology, 18, 1133, 10.1016/j.cub.2008.06.077 · DOI
  17. Down, 2005, Cloning and expression of the large zebrafish protocadherin gene, Fat, Gene Expression Patterns, 5, 483, 10.1016/j.modgep.2004.12.005 · DOI
  18. Downes, 2004, Acetylcholinesterase function is dispensable for sensory neurite growth but is critical for neuromuscular synapse stability, Developmental Biology, 270, 232, 10.1016/j.ydbio.2004.02.027 · DOI
  19. Downes, 2006, Supraspinal input is dispensable to generate glycine-mediated locomotive behaviors in the zebrafish embryo, Journal of Neurobiology, 66, 437, 10.1002/neu.20226 · DOI
  20. Drapeau, 1999, In vivo recording from identifiable neurons of the locomotor network in the developing zebrafish, Journal of Neuroscience Methods, 88, 1, 10.1016/S0165-0270(99)00008-4 · DOI
  21. Drapeau, 2002, Development of the locomotor network in zebrafish, Progress in Neurobiology, 68, 85, 10.1016/S0301-0082(02)00075-8 · DOI · Paper page
  22. Eisen, 1986, Pathway selection by growth cones of identified motoneurones in live zebra fish embryos, Nature, 320, 269, 10.1038/320269a0 · DOI
  23. Ellingsen, 2005, Large-scale enhancer detection in the zebrafish genome, Development, 132, 3799, 10.1242/dev.01951 · DOI
  24. Fetcho, 2008, Zebrafish and motor control over the last decade, Brain Research Reviews, 57, 86, 10.1016/j.brainresrev.2007.06.018 · DOI
  25. Fetcho, 1998, Zebrafish as a model system for studying neuronal circuits and behavior, Annals of the New York Academy of Sciences, 860, 333, 10.1111/j.1749-6632.1998.tb09060.x · DOI
  26. Fetcho, 1997, Imaging neuronal networks in behaving animals, Current Opinion in Neurobiology, 7, 832, 10.1016/S0959-4388(97)80143-2 · DOI
  27. Gleason, 2004, A mutation in serca underlies motility dysfunction in accordion zebrafish, Developmental Biology, 276, 441, 10.1016/j.ydbio.2004.09.008 · DOI
  28. Granato, 1996, Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva, Development, 123, 399, 10.1242/dev.123.1.399 · DOI
  29. Gray, 2001, Zebrafish deadly seven functions in neurogenesis, Developmental Biology, 237, 306, 10.1006/dbio.2001.0381 · DOI
  30. Grillner, 2003, The motor infrastructure: From ion channels to neuronal networks, Nature Reviews Neuroscience, 4, 573, 10.1038/nrn1137 · DOI
  31. Grillner, 2006, Biological pattern generation: The cellular and computational logic of networks in motion, Neuron, 52, 751, 10.1016/j.neuron.2006.11.008 · DOI
  32. Grillner, 2005, Integrative neuroscience: Linking levels of analyses, Current Opinion in Neurobiology, 15, 614, 10.1016/j.conb.2005.08.017 · DOI
  33. Grillner, 1991, Neuronal network generating locomotor behavior in lamprey: Circuitry, transmitters, membrane properties, and simulation, Annual Review of Neuroscience, 14, 169, 10.1146/annurev.ne.14.030191.001125 · DOI
  34. Grunwald, 1988, A neural degeneration mutation that spares primary neurons in the zebrafish, Developmental Biology, 126, 115, 10.1016/0012-1606(88)90245-X · DOI
  35. Hamburger, 1963, Some aspects of the embryology of behavior, The Quarterly Review of Biology, 38, 342, 10.1086/403941 · DOI
  36. Hanson, 2004, Normal patterns of spontaneous activity are required for correct motor axon guidance and the expression of specific guidance molecules, Neuron, 43, 687, 10.1016/j.neuron.2004.08.018 · DOI · Paper page
  37. Higashijima, 2004, Distribution of prospective glutamatergic, glycinergic, and GABAergic neurons in embryonic and larval zebrafish, The Journal of Comparative Neurology, 480, 1, 10.1002/cne.20278 · DOI
  38. Higashijima, 2003, Imaging neuronal activity during zebrafish behavior with a genetically encoded calcium indicator, Journal of Neurophysiology, 90, 3986, 10.1152/jn.00576.2003 · DOI
  39. Higashijima, 2004, Neurotransmitter properties of spinal interneurons in embryonic and larval zebrafish, The Journal of Comparative Neurology, 480, 19, 10.1002/cne.20279 · DOI
  40. Hirata, 2005, Zebrafish bandoneon mutants display behavioral defects due to a mutation in the glycine receptor beta-subunit, Proceedings of the National Academy of Sciences of the United States of America, 102, 8345, 10.1073/pnas.0500862102 · DOI
  41. Hirata, 2004, Accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1, Development, 131, 5457, 10.1242/dev.01410 · DOI
  42. Hirata, 2007, Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore disease, Development, 134, 2771, 10.1242/dev.004531 · DOI
  43. Jontes, 2004, In vivo trafficking and targeting of N-cadherin to nascent presynaptic terminals, The Journal of Neuroscience, 24, 9027, 10.1523/JNEUROSCI.5399-04.2004 · DOI
  44. Kawakami, 2005, Transposon tools and methods in zebrafish, Dev Dyn, 234, 244, 10.1002/dvdy.20516 · DOI
  45. Kimmel, 1974, The development and behavioral characteristics of the startle response in the zebra fish, Developmental Psychobiology, 7, 47, 10.1002/dev.420070109 · DOI
  46. Kudo, 1998, Reorganization of locomotor activity during development in the prenatal rat, Annals of the New York Academy of Sciences, 860, 306, 10.1111/j.1749-6632.1998.tb09058.x · DOI
  47. Kullander, 2005, Genetics moving to neuronal networks, Trends in Neurosciences, 28, 239, 10.1016/j.tins.2005.03.001 · DOI
  48. Kuwada, 1995, Development of the zebrafish nervous system: genetic analysis and manipulation, Curr Opin Neurobiol, 5, 50, 10.1016/0959-4388(95)80086-7 · DOI
  49. Kuwada, 1990, Axonal outgrowth by identified neurons in the spinal cord of zebrafish embryos, Experimental Neurology, 109, 29, 10.1016/S0014-4886(05)80006-8 · DOI
  50. Kuwada, 1990, Development of spinal neurons and tracts in the zebrafish embryo, The Journal of Comparative Neurology, 302, 617, 10.1002/cne.903020316 · DOI
  51. Lefebvre, 2004, Increased neuromuscular activity causes axonal defects and muscular degeneration, Development, 131, 2605, 10.1242/dev.01123 · DOI
  52. Li, 2001, Defining classes of spinal interneuron and their axonal projections in hatchling Xenopus laevis tadpoles, The Journal of Comparative Neurology, 441, 248, 10.1002/cne.1410 · DOI
  53. Li, 2003, The spinal interneurons and properties of glutamatergic synapses in a primitive vertebrate cutaneous flexion reflex, The Journal of Neuroscience, 23, 9068, 10.1523/JNEUROSCI.23-27-09068.2003 · DOI
  54. Liao, 2008, Shared versus specialized glycinergic spinal interneurons in axial motor circuits of larval zebrafish, The Journal of Neuroscience, 28, 12982, 10.1523/JNEUROSCI.3330-08.2008 · DOI · Paper page
  55. Lorent, 2001, The zebrafish space cadet gene controls axonal pathfinding of neurons that modulate fast turning movements, Development, 128, 2131, 10.1242/dev.128.11.2131 · DOI
  56. Low, 2010, touché is required for touch evoked generator potentials within vertebrate sensory neurons, Journal of Neuroscience, 30, 9359, 10.1523/JNEUROSCI.1639-10.2010 · DOI
  57. Low, 2010, Na(V)1.6a is required for normal activation of motor circuits normally excited by tactile stimulation, Developmental Neurobiology, 70, 508, 10.1002/dneu.20791 · DOI
  58. Marder, 1984, Roles for electrical coupling in neural circuits as revealed by selective neuronal deletions, The Journal of Experimental Biology, 112, 147, 10.1242/jeb.112.1.147 · DOI
  59. Masino, 2005, Fictive swimming motor patterns in wild type and mutant larval zebrafish, Journal of Neurophysiology, 93, 3177, 10.1152/jn.01248.2004 · DOI
  60. Mcdearmid, 2006, Rhythmic motor activity evoked by NMDA in the spinal zebrafish larva, Journal of Neurophysiology, 95, 401, 10.1152/jn.00844.2005 · DOI · Paper page
  61. Mcelligott, 2005, Prey tracking by larval zebrafish: Axial kinematics and visual control, Brain, Behavior and Evolution, 66, 177, 10.1159/000087158 · DOI
  62. Mclean, 2007, A topographic map of recruitment in spinal cord, Nature, 446, 71, 10.1038/nature05588 · DOI · Paper page
  63. Mclean, 2008, Using imaging and genetics in zebrafish to study developing spinal circuits in vivo, Developmental Neurobiology, 68, 817, 10.1002/dneu.20617 · DOI
  64. Mclean, 2008, Continuous shifts in the active set of spinal interneurons during changes in locomotor speed, Nature Neuroscience, 11, 1419, 10.1038/nn.2225 · DOI · Paper page
  65. Mendelson, 1986, Development of reticulospinal neurons of the zebrafish I. Time of origin, The Journal of Comparative Neurology, 251, 160, 10.1002/cne.902510203 · DOI
  66. Mendelson, 1986, Development of reticulospinal neurons of the zebrafish II. Early axonal outgrowth and cell body position, The Journal of Comparative Neurology, 251, 172, 10.1002/cne.902510204 · DOI
  67. Menelaou, 2008, Embryonic motor activity and implications for regulating motoneuron axonal pathfinding in zebrafish, The European Journal of Neuroscience, 28, 1080, 10.1111/j.1460-9568.2008.06418.x · DOI
  68. Mongeon, 2008, Synaptic homeostasis in a zebrafish glial glycine transporter mutant, Journal of Neurophysiology, 100, 1716, 10.1152/jn.90596.2008 · DOI
  69. Muller, 2004, Swimming of larval zebrafish: Ontogeny of body waves and implications for locomotory development, The Journal of Experimental Biology, 207, 853, 10.1242/jeb.00821 · DOI
  70. Myers, 1985, Spinal motoneurons of the larval zebrafish, The Journal of Comparative Neurology, 236, 555, 10.1002/cne.902360411 · DOI
  71. Myers, 2005, Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits, Neuron, 46, 37, 10.1016/j.neuron.2005.02.022 · DOI
  72. Nakano, 2010, Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation, Development, 137, 1689, 10.1242/dev.047464 · DOI
  73. Narayanan, 1971, Prenatal development of spontaneous and evoked activity in the rat (Rattus norvegicus albinus), Behaviour, 40, 100, 10.1163/156853971X00357 · DOI
  74. Nasevicius, 2000, Effective targeted gene ‘knockdown’ in zebrafish, Nature Genetics, 26, 216, 10.1038/79951 · DOI
  75. O'donovan, 2005, Calcium imaging of network function in the developing spinal cord, Cell Calcium, 37, 443, 10.1016/j.ceca.2005.01.012 · DOI
  76. O'donovan, 1998, Mechanisms of spontaneous activity in the developing spinal cord and their relevance to locomotion, Annals of the New York Academy of Sciences, 860, 130, 10.1111/j.1749-6632.1998.tb09044.x · DOI
  77. O'malley, 2003, Probing neural circuits in the zebrafish: A suite of optical techniques, Methods, 30, 49, 10.1016/S1046-2023(03)00007-0 · DOI
  78. Ono, 2001, Paralytic zebrafish lacking acetylcholine receptors fail to localize rapsyn clusters to the synapse, The Journal of Neuroscience, 21, 5439, 10.1523/JNEUROSCI.21-15-05439.2001 · DOI
  79. Ono, 2002, The Zebrafish motility mutant twitch once reveals new roles for rapsyn in synaptic function, The Journal of Neuroscience, 22, 6491, 10.1523/JNEUROSCI.22-15-06491.2002 · DOI
  80. Palaisa, 2007, Analysis of zebrafish sidetracked mutants reveals a novel role for Plexin A3 in intraspinal motor axon guidance, Development, 134, 3251, 10.1242/dev.007112 · DOI
  81. Panzer, 2005, Neuromuscular synaptogenesis in wild-type and mutant zebrafish, Developmental Biology, 285, 340, 10.1016/j.ydbio.2005.06.027 · DOI
  82. Parinov, 2004, Tol2 transposon-mediated enhancer trap to identify developmentally regulated zebrafish genes in vivo, Developmental Dynamics, 231, 449, 10.1002/dvdy.20157 · DOI
  83. Pietri, 2009, Glutamate drives the touch response through a rostral loop in the spinal cord of zebrafish embryos, Developmental Neurobiology, 69, 780, 10.1002/dneu.20741 · DOI
  84. Ren, 2003, Ontogeny of rhythmic motor patterns generated in the embryonic rat spinal cord, Journal of Neurophysiology, 89, 1187, 10.1152/jn.00539.2002 · DOI
  85. Ribera, 1998, Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current, The Journal of Neuroscience, 18, 9181, 10.1523/JNEUROSCI.18-22-09181.1998 · DOI
  86. Roberts, 1990, How does a nervous system produce behaviour? A case study in neurobiology, Science Progress, 74, 31
  87. Roberts, 2000, Early functional organization of spinal neurons in developing lower vertebrates, Brain Research Bulletin, 53, 585, 10.1016/S0361-9230(00)00392-0 · DOI
  88. Roberts, 1998, Central circuits controlling locomotion in young frog tadpoles, Annals of the New York Academy of Sciences, 860, 19, 10.1111/j.1749-6632.1998.tb09036.x · DOI
  89. Rodino-Klapac, 2004, Zebrafish topped is required for ventral motor axon guidance, Developmental Biology, 273, 308, 10.1016/j.ydbio.2004.06.007 · DOI
  90. Saint-Amant, 2006, Development of motor networks in zebrafish embryos, Zebrafish, 3, 173, 10.1089/zeb.2006.3.173 · DOI
  91. Saint-Amant, 1998, Time course of the development of motor behaviors in the zebrafish embryo, Journal of Neurobiology, 37, 622, 10.1002/(SICI)1097-4695(199812)37:4<622::AID-NEU10>3.0.CO;2-S · DOI
  92. Saint-Amant, 2001, Synchronization of an embryonic network of identified spinal interneurons solely by electrical coupling, Neuron, 31, 1035, 10.1016/S0896-6273(01)00416-0 · DOI · Paper page
  93. Saint-Amant, 2003, Whole-cell patch-clamp recordings from identified spinal neurons in the zebrafish embryo, Methods in Cell Science, 25, 59, 10.1023/B:MICS.0000006896.02938.49 · DOI
  94. Saint-Amant, 2008, The zebrafish ennui behavioral mutation disrupts acetylcholine receptor localization and motor axon stability, Developmental Neurobiology, 68, 45, 10.1002/dneu.20569 · DOI
  95. Schredelseker, 2005, The beta 1a subunit is essential for the assembly of dihydropyridine-receptor arrays in skeletal muscle, Proceedings of the National Academy of Sciences of the United States of America, 102, 17219, 10.1073/pnas.0508710102 · DOI
  96. Scott, 2009, The Gal4/UAS toolbox in zebrafish: New approaches for defining behavioral circuits, Journal of Neurochemistry, 110, 441, 10.1111/j.1471-4159.2009.06161.x · DOI
  97. Scott, 2007, Targeting neural circuitry in zebrafish using GAL4 enhancer trapping, Nature Methods, 4, 323, 10.1038/nmeth1033 · DOI
  98. Selverston, 2005, A neural infrastructure for rhythmic motor patterns, Cellular and Molecular Neurobiology, 25, 223, 10.1007/s10571-005-3154-8 · DOI
  99. Soffe, 1984, Activity of commissural interneurons in spinal cord of Xenopus embryos, Journal of Neurophysiology, 51, 1257, 10.1152/jn.1984.51.6.1257 · DOI
  100. Szobota, 2007, Remote control of neuronal activity with a light-gated glutamate receptor, Neuron, 54, 535, 10.1016/j.neuron.2007.05.010 · DOI
  101. Takahashi, 2002, In vivo imaging of functional inhibitory networks on the mauthner cell of larval zebrafish, The Journal of Neuroscience, 22, 3929, 10.1523/JNEUROSCI.22-10-03929.2002 · DOI
  102. Tazerart, 2007, Contribution of persistent sodium current to locomotor pattern generation in neonatal rats, Journal of Neurophysiology, 98, 613, 10.1152/jn.00316.2007 · DOI
  103. Tazerart, 2008, The persistent sodium current generates pacemaker activities in the central pattern generator for locomotion and regulates the locomotor rhythm, The Journal of Neuroscience, 28, 8577, 10.1523/JNEUROSCI.1437-08.2008 · DOI
  104. Van Eeden, 1996, Mutations affecting somite formation and patterning in the zebrafish, Danio rerio, Development, 123, 153, 10.1242/dev.123.1.153 · DOI
  105. Westerfield, 1990, Pathfinding and synapse formation in a zebrafish mutant lacking functional acetylcholine receptors, Neuron, 4, 867, 10.1016/0896-6273(90)90139-7 · DOI
  106. Westerfield, 1986, Identified motoneurons and their innervation of axial muscles in the zebrafish, The Journal of Neuroscience, 6, 2267, 10.1523/JNEUROSCI.06-08-02267.1986 · DOI
  107. Yvert, 2004, Multiple spontaneous rhythmic activity patterns generated by the embryonic mouse spinal cord occur within a specific developmental time window, Journal of Neurophysiology, 91, 2101, 10.1152/jn.01095.2003 · DOI
  108. Zeller, 1999, The zebrafish diwanka gene controls an early step of motor growth cone migration, Development, 126, 3461, 10.1242/dev.126.15.3461 · DOI
  109. Zhang, 2004, Zebrafish unplugged reveals a role for muscle-specific kinase homologs in axonal pathway choice, Nature Neuroscience, 7, 1303, 10.1038/nn1350 · DOI
  110. Zhong, 2007, Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord, The Journal of Neuroscience, 27, 4507, 10.1523/JNEUROSCI.0124-07.2007 · DOI
  111. Zhou, 2006, Non-sense mutations in the dihydropyridine receptor beta1 gene, CACNB1, paralyze zebrafish relaxed mutants, Cell Calcium, 39, 227, 10.1016/j.ceca.2005.10.015 · DOI

Cited by

Sorted by citations

Metadata

Authors
Saint-Amant, L.
Venue
Progress in Brain Research
Publisher
Elsevier
Published
2010
Volume
187
Pages
47-61
ISSN
0079-6123 (ISSN-L)
DOI
10.1016/b978-0-444-53613-6.00004-6
OpenAlex
W198540525
Cited by
24
References
6
Citations by year
2026: 1 · 2025: 2 · 2024: 2 · 2023: 2 · 2021: 4 · 2020: 2 · 2019: 1 · 2017: 2 · 2015: 1 · 2014: 2 · 2013: 1 · 2012: 2
FWCI
2.56
Type
book chapter
Language
en
Open access
closed
Locations
  • Progress in brain research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Zebrafish Biomedical Research Applications
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords
motor rhythm, zebrafish embryos, neural circuit development, neural oscillations, neuronal network maturation, embryonic nervous system development, neuronal activity
MeSH terms
Animals, Embryo, Nonmammalian, Motor Activity, Mutation, Periodicity, Spinal Cord, Zebrafish

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review