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Recent insights into innate and adaptive immune responses to Giardia
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“Reduced regulatory T-cell activity, insufficient Th17-related responses, and altered sIgA production may increase susceptibility to G. intestinalis infection and contribute to persistent gastrointestinal inflammation (Aboulhoda et al. 2024; Singer et al. 2019; Yordanova et al. 2019; Zhao et al. 2023).”
From Parasites and allergies: a complex bidirectional relationship from evolutionary origins to modern therapeutics (2026) · cites this paper as Singer et al. 2019
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Th17: An Effector CD4 T Cell Lineage with Regulatory T Cell Ties
Weaver, C. T., Harrington, L. E., Mangan, P. R., Gavrieli, M., & Murphy, K. M. (2006) · Immunity · doi:10.1016/j.immuni.2006.06.002 · Cited by 1,422 · cited 3×
“Interleukin-6 helps to drive the differentiation of IL-17 producing (Th17) T cells in vitro (Weaver et al., 2006), and as such, mice that lack IL-6 ought to have reduced IL-17 expression.”
BackgroundAdvances in understanding Giardia: Determinants and mechanisms of chronic sequelae
Bartelt, L. A., & Sartor, R. B. (2015) · F1000Prime Reports · doi:10.12703/p7-62 · Cited by 154
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Packi, K., Świerczewski, D., Klimczak, S., Ochab, D., Gałęziewska, J., Gromek, P., Kruczkowska, W., Płuciennik, E., Kałuzińska-Kołat, Ż., & Kołat, D. (2026) · Antonie van Leeuwenhoek · doi:10.1007/s10482-026-02425-4
Metadata
- Venue
- Advances in Parasitology
- Publisher
- Elsevier
- Published
- 2019
- Pages
- 171-208
- ISSN
- 0065-308X
- PMC
- PMC7086480
- Cited by
- 50
- References
- 2
- Language
- en
- Funders
- National Institutes of Health
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