The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Matrix Metalloproteinases in Myocardial Infarction and Heart Failure
Open accessAbstract
Cardiovascular disease (CVD) is the leading cause of death, accounting for 600,000 deaths each year in the U.S. In addition, heart failure accounts for 37% of healthcare spending. Matrix metalloproteinases (MMPs) increase after myocardial infarction (MI) and correlate with left ventricular dysfunction in heart failure patients. MMPs regulate the remodeling process by facilitating extracellular matrix (ECM) turnover and inflammatory signaling. Due to the critical role MMPs play during cardiac remodeling, there is a need to better understand the pathophysiological mechanism of MMPs, including the biological function of the downstream products of MMP proteolysis. Future studies developing new therapeutic targets that inhibit specific MMP actions to limit the development of heart failure post-MI are warranted. This book chapter focuses on the role of MMPs post-MI, the efficiency of MMPs as biomarkers for MI or heart failure, and the future of MMPs and their cleavage products as targets for prevention of post-MI heart failure.
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Heart Disease and Stroke Statistics—2012 Update: A Report From the American Heart Association
Writing Group Members, Roger, V. L., Go, A. S., Lloyd-Jones, D. M., Benjamin, E. J., Berry, J. D., Borden, W. B., Bravata, D. M., Dai, S., Ford, E. S., et al. (2012) · Circulation · doi:10.1161/cir.0b013e31823ac046 · Cited by 7,333
Visse, R., & Nagase, H. (2003) · Circulation Research · doi:10.1161/01.res.0000070112.80711.3d · Cited by 4,575
Cohn, J. N., Ferrari, R., & Sharpe, N. (2000) · Journal of the American College of Cardiology · doi:10.1016/s0735-1097(99)00630-0 · Cited by 2,161
Cardiac fibroblasts: At the heart of myocardial remodeling
Porter, K. E., & Turner, N. A. (2009) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2009.05.002 · Cited by 1,010
Heymans, S., Luttun, A., Nuyens, D., Theilmeier, G., Creemers, E., Moons, L., Dyspersin, G. D., Cleutjens, J. P. M., Shipley, M., Angellilo, A., et al. (1999) · Nature Medicine · doi:10.1038/13459 · Cited by 794
Blankenberg, S., Rupprecht, H. J., Poirier, O., Bickel, C., Smieja, M., Hafner, G., Meyer, J., Cambien, F., & Tiret, L. (2003) · Circulation · doi:10.1161/01.cir.0000058700.41738.12 · Cited by 755
Cellular Mechanisms for Human Procollagenase-3 (MMP-13) Activation
Knäuper, V., Will, H., López-Otin, C., Smith, B., Atkinson, S. J., Stanton, H., Hembry, R. M., & Murphy, G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.29.17124 · Cited by 747
The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1
Mu, D., Cambier, S., Fjellbirkeland, L., Baron, J. L., Munger, J. S., Kawakatsu, H., Sheppard, D., Broaddus, V. C., & Nishimura, S. L. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200109100 · Cited by 729
Awtry, E. H., & Loscalzo, J. (2000) · Circulation · doi:10.1161/01.cir.101.10.1206 · Cited by 690
Shubeita, H. E., McDonough, P. M., Harris, A. N., Knowlton, K. U., Glembotski, C. C., Brown, J. H., & Chien, K. R. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30538-0 · Cited by 645
Cited by
Extracellular matrix remodeling and cardiac fibrosis
Li, L., Zhao, Q., & Kong, W. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.01.013 · Cited by 419
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Mishra, S., & Kass, D. A. (2021) · Nature Reviews Cardiology · doi:10.1038/s41569-020-00480-6 · Cited by 417
Role of Cardiac Macrophages on Cardiac Inflammation, Fibrosis and Tissue Repair
Lafuse, W. P., Wozniak, D. J., & Rajaram, M. V. S. (2020) · Cells · doi:10.3390/cells10010051 · Cited by 401
Multifunctional intracellular matrix metalloproteinases: implications in disease
Bassiouni, W., Ali, M. A. M., & Schulz, R. (2021) · The FEBS Journal · doi:10.1111/febs.15701 · Cited by 377
Plasma biomarkers associated with adverse outcomes in patients with calcific aortic stenosis
Vidula, M. K., Orlenko, A., Zhao, L., Salvador, L., Small, A. M., Horton, E., Cohen, J. B., Adusumalli, S., Denduluri, S., Kobayashi, T., et al. (2021) · European Journal of Heart Failure · doi:10.1002/ejhf.2361 · Cited by 38
Metadata
- Authors
- DeLeon-Pennell, K. Y., Meschiari, C. A., Jung, M., & Lindsey, M. L.
- Venue
- Progress in Molecular Biology and Translational Science
- Publisher
- Elsevier
- Published
- 2017
- Volume
- 147
- Pages
- 75-100
- ISSN
- 1877-1173 (ISSN-L)
- OpenAlex
- W2596947530
- Cited by
- 287
- References
- 114
- FWCI
- 123.30
- Type
- book chapter
- Language
- en
- Open access
- green
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