Results of an international round robin for the quantification of serum non-transferrin-bound iron: Need for defining standardization and a clinically relevant isoform

Measuring agreement in method comparison studies

Bland, J. M., & Altman, D. G. (1999) · Statistical Methods in Medical Research · doi:10.1177/096228029900800204 · Cited by 9,619 · see citing works

Measuring agreement in method comparison studies

Bland, J. M., & Altman, D. G. (1999) · Statistical Methods in Medical Research · doi:10.1191/096228099673819272 · Cited by 9,619 · see citing works

The roles of iron in health and disease

Lieu, P. T., Heiskala, M. K., Peterson, P. A., & Yang, Y. M. (2001) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(00)00006-6 · Cited by 813 · see citing works

Labile plasma iron in iron overload: redox activity and susceptibility to chelation

Esposito, B. P., Breuer, W., Sirankapracha, P., Pootrakul, P., Hershko, C., & Cabantchik, Z. I. (2003) · Blood · doi:10.1182/blood-2003-03-0807 · Cited by 475 · see citing works

Non-transferrin-bound iron in plasma or serum from patients with idiopathic hemochromatosis

Grootveld, M. C., Bell, J. D., Halliwell, B. B., Aruoma, O. I., Bomford, A. B., & Sadler, P. J. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)83758-9 · Cited by 404 · see citing works

The importance of non-transferrin bound iron in disorders of iron metabolism

Breuer, W., Hershko, C., & Cabantchik, Z. I. (2000) · Transfusion Science · doi:10.1016/s0955-3886(00)00087-4 · Cited by 268 · see citing works

Iron, Atherosclerosis, and Ischemic Heart Disease

de Valk, B., & Marx, J. J. M. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.14.1542 · Cited by 250 · see citing works

Pathophysiology of Iron Overloada

Hershko, C., Link, G., & Cabantchik, I. Z. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb10475.x · Cited by 246 · see citing works

Quantification of Non-Transferrin-Bound Iron in the Presence of Unsaturated Transferrin

Gosriwatana, I., Loréal, O., Lu, S., Brissot, P., Porter, J. B., & Hider, R. C. (1999) · Analytical Biochemistry · doi:10.1006/abio.1999.4216 · Cited by 167 · see citing works

Nature of nontransferrin‐bound iron

Hider, R. C. (2002) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2002.0320s1050.x · Cited by 139 · see citing works

Labile plasma iron (LPI) as an indicator of chelatable plasma redox activity in iron-overloaded β-thalassemia/HbE patients treated with an oral chelator

Pootrakul, P., Breuer, W. V., Sametband, M., Sirankapracha, P., Hershko, C., & Cabantchik, Z. I. (2004) · Blood · doi:10.1182/blood-2004-02-0630 · Cited by 134 · see citing works

The assessment of serum nontransferrin-bound iron in chelation therapy and iron supplementation

Breuer, W. V., Ronson, A., Slotki, I. N., Abramov, A., Hershko, C., & Cabantchik, Z. I. (2000) · Blood · doi:10.1182/blood.v95.9.2975.009k03_2975_2982 · Cited by 132 · see citing works

Determination of non-transferrin-bound iron in genetic hemochromatosis using a new HPLC-based method

Loréal, O., Gosriwatana, I., Guyader, D., Porter, J. B., Brissot, P., & Hider, R. C. (2000) · Journal of Hepatology · doi:10.1016/s0168-8278(00)80240-8 · Cited by 118 · see citing works

Non‐transferrin‐bound iron is present in serum of hereditary haemochromatosis heterozygotes

Valk, D., Addicks, Gosriwatana, Lü, Hider, & Marx, M. (2000) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2000.00628.x · Cited by 114 · see citing works

Nontransferrin-bound iron in plasma from hemochromatosis patients: effect of phlebotomy therapy

Aruoma, O., Bomford, A. B., Polson, R., & Halliwell, B. B. (1988) · Blood · doi:10.1182/blood.v72.4.1416.1416 · Cited by 110 · see citing works

A Fluorescence-Based One-Step Assay for Serum Non-Transferrin-Bound Iron

Breuer, W. V., & Cabantchik, Z. I. (2001) · Analytical Biochemistry · doi:10.1006/abio.2001.5378 · Cited by 102 · see citing works

Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis

Chua, A. C. G., Olynyk, J. K., Leedman, P. J., & Trinder, D. (2004) · Blood · doi:10.1182/blood-2003-11-3872 · Cited by 94 · see citing works

Nontransferrin‐bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion

Kooistra, M. P., Kersting, S., Gosriwatana, I., Lu, S. L., Nijhoff‐Schutte, J., Hider, R. C., & Marx, J. J. M. (2002) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2002.0320s1036.x · Cited by 84 · see citing works

Nontransferrin-bound Iron in Serum of Patients Receiving Bone Marrow Transplants

Dürken, M., Nielsen, P., Knobel, S., Finckh, B., Herrnring, C., Dresow, B., Kohlschütter, B., Stockschläder, M., Krüger, W., Kohlschütter, A., et al. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00497-2 · Cited by 75 · see citing works

Non‐transferrin‐bound iron and cellular toxicity

Anderson, G. J. (1999) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.1999.01828.x · Cited by 66 · see citing works

Bleomycin-detectable Iron Assay for Non-Transferrin-bound Iron in Hematologic Malignancies

von Bonsdorff, L., Lindeberg, E., Sahlstedt, L., Lehto, J., & Parkkinen, J. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.2.307 · Cited by 54 · see citing works

Non-transferrin-bound iron in long-term transfusion in children with congenital anemias

Wang, W. C., Ahmed, N. K., & Hanna, M. (1986) · The Journal of Pediatrics · doi:10.1016/s0022-3476(86)80832-0 · Cited by 53 · see citing works

Effective binding of free iron by a single intravenous dose of human apotransferrin in haematological stem cell transplant patients

Sahlstedt, L., von Bonsdorff, L., Ebeling, F. T., Ruutu, T., & Parkkinen, J. (2002) · British Journal of Haematology · doi:10.1046/j.1365-2141.2002.03836.x · Cited by 43 · see citing works

Non‐transferrin‐bound iron and hepatic dysfunction in African dietary iron overload

McNamara, L., MacPhail, A. P., Mandishona, E., Bloom, P. D., Paterson, A. C., Rouault, T. A., & Gordeuk, V. R. (1999) · Journal of Gastroenterology and Hepatology · doi:10.1046/j.1440-1746.1999.01830.x · Cited by 39 · see citing works

Red blood cell antioxidant and iron status in alcoholic and nonalcoholic cirrhosis

Fiorelli, G., Feo, T. M. D., Duca, L., Tavazzi, D., Nava, I., Fargion, S. R., & Cappellini, M. D. (2002) · European Journal of Clinical Investigation · doi:10.1046/j.1365-2362.2002.0320s1021.x · Cited by 19 · see citing works

The intracellular iron sensor calcein is catalytically oxidatively degraded by iron(II) in a hydrogen peroxide-dependent reaction

Hasinoff, B. B. (2003) · Journal of Inorganic Biochemistry · doi:10.1016/s0162-0134(03)00099-0 · Cited by 18 · see citing works

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

Lichten, L. A., & Cousins, R. J. (2009) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-033009-083312 · Cited by 732 · see citing works

Non-transferrin bound iron: a key role in iron overload and iron toxicity

Brissot, P., Ropert, M., Le Lan, C., & Loréal, O. (2012) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2011.07.014 · Cited by 654 · see citing works

Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells

Liuzzi, J. P., Aydemir, F., Nam, H., Knutson, M. D., & Cousins, R. J. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606424103 · Cited by 577 · see citing works

Intracellular iron transport and storage: from molecular mechanisms to health implications

Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526 · see citing works

The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: insights into the potential of various iron therapies to induce oxidative and nitrosative stress

Koskenkorva-Frank, T. S., Weiss, G., Koppenol, W. H., & Burckhardt, S. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.09.001 · Cited by 406 · see citing works

Labile iron in cells and body fluids: Physiology, pathology, and pharmacology

Cabantchik, Z. I. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00045 · Cited by 306 · see citing works

Oxidative stress and inflammation in iron‐overloaded patients with β‐thalassaemia or sickle cell disease

Walter, P. B., Fung, E. B., Killilea, D. W., Jiang, Q., Hudes, M. L., Madden, J., Porter, J. B., Evans, P., Vichinsky, E. P., & Harmatz, P. (2006) · British Journal of Haematology · doi:10.1111/j.1365-2141.2006.06277.x · Cited by 288 · see citing works

The multifaceted role of iron in renal health and disease

van Swelm, R. P. L., Wetzels, J. F. M., & Swinkels, D. W. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0197-5 · Cited by 279 · see citing works

Laboratory methodologies for indicators of iron status: strengths, limitations, and analytical challenges

Pfeiffer, C. M., & Looker, A. C. (2017) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.117.155887 · Cited by 260 · see citing works

Iron overload and toxicity: the hidden risk of multiple blood transfusions

Shander, A., Cappellini, M. D., & Goodnough, L. T. (2009) · Vox Sanguinis · doi:10.1111/j.1423-0410.2009.01207.x · Cited by 236 · see citing works

Advances in Quantitative Hepcidin Measurements by Time-of-Flight Mass Spectrometry

Swinkels, D. W., Girelli, D., Laarakkers, C. M., Kroot, J. J., Campostrini, N., Kemna, E., & Tjalsma, H. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002706 · Cited by 202 · see citing works

On risks and benefits of iron supplementation recommendations for iron intake revisited

Schümann, K., Ettle, T., Szegner, B., Elsenhans, B., & Solomons, N. W. (2007) · Journal of Trace Elements in Medicine and Biology · doi:10.1016/j.jtemb.2007.06.002 · Cited by 189 · see citing works

Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization

Kroot, J. J., Kemna, E., Bansal, S. S., Busbridge, M., Campostrini, N., Girelli, D., Hider, R. C., Koliaraki, V., Mamalaki, A., Olbina, G., et al. (2009) · Haematologica · doi:10.3324/haematol.2009.010322 · Cited by 177 · see citing works

Iron homeostasis and organismal aging

Zeidan, R. S., Han, S. M., Leeuwenburgh, C., & Xiao, R. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101510 · Cited by 150 · see citing works

High nontransferrin bound iron levels and heart disease in thalassemia major

Piga, A. G., Longo, F., Duca, L., Roggero, S., Vinciguerra, T., Calabrese, R., Hershko, C., & Cappellini, M. D. (2008) · American Journal of Hematology · doi:10.1002/ajh.21317 · Cited by 144 · see citing works

Guidelines for quantifying iron overload

Wood, J. C. (2014) · Hematology · doi:10.1182/asheducation-2014.1.210 · Cited by 140 · see citing works

Improvement in oxidative stress and antioxidant parameters in β-thalassemia/Hb E patients treated with curcuminoids

Kalpravidh, R. W., Siritanaratkul, N., Insain, P., Charoensakdi, R., Panichkul, N., Hatairaktham, S., Srichairatanakool, S., Phisalaphong, C., Rachmilewitz, E. A., & Fucharoen, S. (2009) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2009.10.057 · Cited by 136 · see citing works

Estimating tissue iron burden: current status and future prospects

Wood, J. C. (2015) · British Journal of Haematology · doi:10.1111/bjh.13374 · Cited by 130 · see citing works

Common Presence of Non–Transferrin-Bound Iron Among Patients With Type 2 Diabetes

Lee, D.-H., Liu, D. Y., Jacobs, D. R., Shin, H.-R., Song, K., Lee, I.-K., Kim, B., & Hider, R. C. (2006) · Diabetes Care · doi:10.2337/dc05-2471 · Cited by 128 · see citing works

Regulation of hepcidin: Insights from biochemical analyses on human serum samples

Kemna, E., Kartikasari, A. E. R., van Tits, L. J. H., Pickkers, P., Tjalsma, H., & Swinkels, D. W. (2007) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2007.10.002 · Cited by 116 · see citing works

Hereditary Hemochromatosis: Genetic Complexity and New Diagnostic Approaches

Swinkels, D. W., Janssen, M. C. H., Bergmans, J., & Marx, J. J. M. (2006) · Clinical Chemistry · doi:10.1373/clinchem.2006.068684 · Cited by 116 · see citing works

Regulation of iron pathways in response to hypoxia

Chepelev, N. L., & Willmore, W. G. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.12.023 · Cited by 102 · see citing works

Diagnosis and management of transfusion iron overload: The role of imaging

Wood, J. C. (2007) · American Journal of Hematology · doi:10.1002/ajh.21099 · Cited by 102 · see citing works

Serum hepcidin levels are innately low in HFE‐related haemochromatosis but differ between C282Y‐homozygotes with elevated and normal ferritin levels

van Dijk, B. A. C., Laarakkers, C. M., Klaver, S. M., Jacobs, E. M. G., van Tits, L. J. H., Janssen, M. C. H., & Swinkels, D. W. (2008) · British Journal of Haematology · doi:10.1111/j.1365-2141.2008.07273.x · Cited by 95 · see citing works

Non Transferrin Bound Iron: Nature, Manifestations and Analytical Approaches for Estimation

Patel, M., & Ramavataram, D. (2012) · Indian Journal of Clinical Biochemistry · doi:10.1007/s12291-012-0250-7 · Cited by 94 · see citing works

Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders

de Swart, L., Hendriks, J. C. M., van der Vorm, L. N., Cabantchik, Z. I., Evans, P., Hod, E. A., Brittenham, G. M., Furman, Y., Wójczyk, B. S., Janssen, M. C. H., et al. (2015) · Haematologica · doi:10.3324/haematol.2015.133983 · Cited by 92 · see citing works

Neonatal iron overload and tissue siderosis due to gestational alloimmune liver disease

Bonilla, S., Prozialeck, J. D., Malladi, P., Pan, X., Yu, S., Melín‐Aldana, H., & Whitington, P. F. (2012) · Journal of Hepatology · doi:10.1016/j.jhep.2012.01.010 · Cited by 79 · see citing works

Clinical consequences of iron overload from chronic red blood cell transfusions, its diagnosis, and its management by chelation therapy

Shander, A., & Sazama, K. J. (2010) · Transfusion · doi:10.1111/j.1537-2995.2009.02551.x · Cited by 74 · see citing works

Influence of non-enzymatic post-translation modifications on the ability of human serum albumin to bind iron

Silva, A. M. N., & Hider, R. C. (2009) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2009.06.003 · Cited by 72 · see citing works

Endothelial activation and induction of monocyte adhesion by nontransferrin‐bound iron present in human sera

Kartikasari, A. E. R., Georgiou, N., Visseren, F. L. J., Kats-Renaud, H. J. V., van Asbeck, B. S., & Marx, J. J. M. (2005) · The FASEB Journal · doi:10.1096/fj.05-4700fje · Cited by 69 · see citing works

The (Bio)Chemistry of Non-Transferrin-Bound Iron

Silva, A. M. N., & Rangel, M. (2022) · Molecules · doi:10.3390/molecules27061784 · Cited by 65 · see citing works

Iron Overload in Thalassemia and Related Conditions: Therapeutic Goals and Assessment of Response to Chelation Therapies

Porter, J. B., & Shah, F. (2010) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2010.08.015 · Cited by 63 · see citing works

Non–Transferrin-Bound Iron and Risk of Coronary Heart Disease in Postmenopausal Women

van der A, D. L., Marx, J. J. M., Grobbee, D. E., Kamphuis, M. H., Georgiou, N., van Kats-Renaud, J. H., Breuer, W. V., Cabantchik, Z. I., Roest, M., Voorbij, H. A. M., et al. (2006) · Circulation · doi:10.1161/circulationaha.105.545350 · Cited by 60 · see citing works

Iron-binding antioxidant capacity is impaired in diabetes mellitus

Campenhout, A. V., Campenhout, C. V., Lagrou, A., Moorkens, G. H., Block, C. E. M. D., & Manuel‐y‐Keenoy, B. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.01.010 · Cited by 51 · see citing works

Scientific and Regulatory Considerations for Generic Complex Drug Products Containing Nanomaterials

Zheng, N., Sun, D. D., Zou, P., & Jiang, W. (2017) · The AAPS Journal · doi:10.1208/s12248-017-0044-1 · Cited by 50 · see citing works

Does non-transferrin bound iron contribute to transfusion related immune-modulation in preterms?

Stark, M. J., Keir, A., & Andersen, C. C. (2013) · Archives of Disease in Childhood Fetal & Neonatal · doi:10.1136/archdischild-2012-303353 · Cited by 45 · see citing works

Non-transferrin bound iron

Angoro, B., Motshakeri, M., Hemmaway, C. J., Svirskis, D. M., & Sharma, M. (2022) · Clinica Chimica Acta · doi:10.1016/j.cca.2022.04.004 · Cited by 45 · see citing works

Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial

Wood, J. C., Glynos, T., Thompson, A. A., Giardina, P. J., Harmatz, P., Kang, B. P. S., Paley, C. S., & Coates, T. D. (2011) · Haematologica · doi:10.3324/haematol.2010.032862 · Cited by 44 · see citing works

Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin‐bound iron

Hider, R. C., Silva, A. M. N., Podinovskaia, M., & Ma, Y. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05573.x · Cited by 43 · see citing works

Excessive Body Iron Stores Are Not Associated with Risk of Coronary Heart Disease in Women

Sun, Q., Ma, J., Rifai, N., Franco, O. H., Rexrode, K. M., & Hu, F. B. (2008) · Journal of Nutrition · doi:10.3945/jn.108.097766 · Cited by 41 · see citing works

Controversies on the Consequences of Iron Overload and Chelation in MDS

Vinchi, F., Hell, S., & Platzbecker, U. (2020) · HemaSphere · doi:10.1097/hs9.0000000000000357 · Cited by 42 · see citing works

Non‐transferrin bound iron in Thalassemia: Differential detection of redox active forms in children and older patients

Breuer, W. V., Ghoti, H., Shattat, A., Goldfarb, A. W., Koren, A., Levin, C., Rachmilewitz, E. A., & Cabantchik, Z. I. (2011) · American Journal of Hematology · doi:10.1002/ajh.22203 · Cited by 41 · see citing works

Management of the ThalassemiasPreprint

Olivieri, N. F., & Brittenham, G. (2013) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a011767 · Cited by 40 · see citing works

Non-Transferrin-Bound Iron Is Associated with Enhanced Staphylococcus aureus Growth in Hemodialysis Patients Receiving Intravenous Iron Sucrose

Pai, A. B., Pai, M. P., Depczynski, J., McQuade, C. R., & Mercier, R.-C. (2006) · American Journal of Nephrology · doi:10.1159/000094343 · Cited by 39 · see citing works

Mammalian Iron Metabolism

Valerio, L. G. (2007) · Toxicology Mechanisms and Methods · doi:10.1080/15376510701556690 · Cited by 37 · see citing works

A novel method for non-transferrin-bound iron quantification by chelatable fluorescent beads based on flow cytometry

Ma, Y., Podinovskaia, M., Evans, P., Emma, G., Schaible, U. E., Porter, J. B., & Hider, R. C. (2014) · Biochemical Journal · doi:10.1042/bj20140795 · Cited by 31 · see citing works

Pathogenesis, Diagnosis, and Clinical Implications of Hereditary Hemochromatosis—The Cardiological Point of View

Daniłowicz‐Szymanowicz, L., Świątczak, M., Sikorska, K., Starzyński, R. R., Raczak, A., & Lipiński, P. (2021) · Diagnostics · doi:10.3390/diagnostics11071279 · Cited by 29 · see citing works

Blood donation, body iron status and carotid intima-media thickness

Engberink, M. F., Geleijnse, J. M., Durga, J., Swinkels, D. W., de Kort, W. L. A. M., Schouten, E. G., & Verhoef, P. (2007) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2007.01.031 · Cited by 30 · see citing works

Improved quantification for non-transferrin-bound iron measurement using high-performance liquid chromatography by reducing iron contamination

Ikuta, K. (2011) · Molecular Medicine Reports · doi:10.3892/mmr.2011.518 · Cited by 30 · see citing works

Fortification Iron as Ferrous Sulfate Plus Ascorbic Acid Is More Rapidly Absorbed Than as Sodium Iron EDTA but Neither Increases Serum Nontransferrin-Bound Iron in Women1–3

Troesch, B., Egli, I. M., Zeder, C., Hurrell, R. F., & Zimmermann, M. B. (2011) · Journal of Nutrition · doi:10.3945/jn.110.136127 · Cited by 28 · see citing works

Iron overload and toxicity: implications for anesthesiologists

Shander, A., Berth, U., Betta, J., & Javidroozi, M. (2012) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2011.12.005 · Cited by 26 · see citing works

Non-transferrin bound iron measurement is influenced by chelator concentration

Kolb, A. M., Smit, N. P. M., Lentz-Ljuboje, R., Osanto, S., & PELT, J. V. (2008) · Analytical Biochemistry · doi:10.1016/j.ab.2008.11.003 · Cited by 25 · see citing works

Non-transferrin-bound iron is associated with plasma level of soluble intercellular adhesion molecule-1 but not with in vivo low-density lipoprotein oxidation

van Tits, L. J. H., Jacobs, E. M. G., Swinkels, D. W., Lemmers, H., van der Vleuten, G. M., Graaf, J. D., & Stalenhoef, A. F. H. (2006) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2006.08.012 · Cited by 24 · see citing works

Early detection of cardiac involvement in thalassemia: From bench to bedside perspective

Koonrungsesomboon, N. (2013) · World Journal of Cardiology · doi:10.4330/wjc.v5.i8.270 · Cited by 23 · see citing works

Impact of Oral Iron Challenges on Circulating Non-Transferrin-Bound Iron in Healthy Guatemalan Males

Schümann, K., Kroll, S., Romero‐Abal, M., Georgiou, N., Marx, J. J. M., Weiß, G., & Solomons, N. W. (2012) · Annals of Nutrition and Metabolism · doi:10.1159/000336177 · Cited by 23 · see citing works

Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron

Messner, D. J., & Kowdley, K. (2008) · BMC Gastroenterology · doi:10.1186/1471-230x-8-2 · Cited by 22 · see citing works

Timed non-transferrin bound iron determinations probe the origin of chelatable iron pools during deferiprone regimens and predict chelation response

Aydınok, Y., Evans, P., Manz, C. Y., & Porter, J. B. (2011) · Haematologica · doi:10.3324/haematol.2011.056317 · Cited by 22 · see citing works

Diagnosis and treatment of cardiac iron overload in transfusion-dependent thalassemia patients

Siri‐Angkul, N., Chattipakorn, S. C., & Chattipakorn, N. (2018) · Expert Review of Hematology · doi:10.1080/17474086.2018.1476134 · Cited by 22 · see citing works

Flow cytometric estimation of ‘labile iron pool’ in human white blood cells reveals a positive association with ageing

Doulias, P.-T., Vlachou, C., Boudouri, C., Kanavaros, P., Siamopoulos, K. C., & Galaris, D. (2008) · Free Radical Research · doi:10.1080/10715760801911649 · Cited by 21 · see citing works

Role of Non-Transferrin-Bound Iron in the pathogenesis of cardiotoxicity in patients with ST-elevation myocardial infarction assessed by Cardiac Magnetic Resonance Imaging.

Roghi, A., Poggiali, E., Duca, L., Mafrici, A., Pedrotti, P., Paccagnini, S., Brenna, S., Galli, A., Consonni, D., & Cappellini, M. (2015) · International Journal of Cardiology · doi:10.1016/j.ijcard.2015.07.056 · Cited by 20 · see citing works

The Essential Role of Iron in Biology

Crichton, R. R. (2016) · doi:10.1002/9781118925645.ch2 · Cited by 20 · see citing works

The selective quantification of iron by hexadentate fluorescent probes

Ma, Y. M., & Hider, R. C. (2009) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2009.09.052 · Cited by 19 · see citing works

The Molecular and Cellular Basis of Iron Toxicity in Iron Overload (IO) Disorders. Diagnostic and Therapeutic Approaches

Cabantchik, Z. I., Sohn, Y., Breuer, W. V., & Espósito, B. P. (2013) · Thalassemia Reports · doi:10.4081/thal.2013.s1.e3 · Cited by 19 · see citing works

Snapshots of Iron Speciation: Tracking the Fate of Iron Nanoparticle Drugs via a Liquid Chromatography–Inductively Coupled Plasma–Mass Spectrometric Approach

Neu, H. M., Alexishin, S. A., Brandis, J. E. P., Williams, A. M., Li, W., Sun, D. D., Zheng, N., Jiang, W., Zimrin, A. B., Fink, J. C., et al. (2019) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.8b01215 · Cited by 19 · see citing works

Erythroferrone, the new iron regulator: evaluation of its levels in Egyptian patients with beta thalassemia

El‐Gamal, R. A. E., Abdel-Messih, I. Y., Habashy, D. M., Zaiema, S. E. G. E., & Pessar, S. A. (2019) · Annals of Hematology · doi:10.1007/s00277-019-03882-w · Cited by 18 · see citing works

Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

Brewer, C., Otto‐Duessel, M., Lykkesfeldt, J., Nick, H., & Wood, J. C. (2012) · Experimental Hematology · doi:10.1016/j.exphem.2012.06.005 · Cited by 14 · see citing works

The clinical relevance of detectable plasma iron species in iron overload states and subsequent to intravenous iron‐carbohydrate administration

Garbowski, M., Cabantchik, I. Z., Hershko, C., Hider, R. C., & Porter, J. B. (2022) · American Journal of Hematology · doi:10.1002/ajh.26819 · Cited by 14 · see citing works

Genetic screens reveal CCDC115 as a modulator of erythroid iron and heme trafficking

Sobh, A., Loguinov, A. V., Zhou, J., Jenkitkasemwong, S., Zeidan, R. S., Ahmadie, N. E., Tagmount, A., Knutson, M. D., Fraenkel, P. G., & Vulpe, C. D. (2020) · American Journal of Hematology · doi:10.1002/ajh.25899 · Cited by 12 · see citing works

Iron and malaria: a dangerous liaison?

Moya‐Alvarez, V., Bodeau‐Livinec, F., & Cot, M. (2016) · Nutrition Reviews · doi:10.1093/nutrit/nuw021 · Cited by 13 · see citing works

Therapeutic potential of synthetic and natural iron chelators against ferroptosis

Prabhune, N. M., Ameen, B., & Prabhu, S. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03640-4 · Cited by 12 · see citing works

Automated assay for non-transferrin-bound iron in serum samples

Prezelj, M., & Knap, B. (2010) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2010.287 · Cited by 12 · see citing works

Kinetics of Iron Import into Developing Mouse Organs Determined by a Pup-swapping Method

Chakrabarti, M., Barlas, M. N., McCormick, S. P., Lindahl, L. S., & Lindahl, P. A. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.606731 · Cited by 12 · see citing works

β-Thalassemia: Genotypes and Phenotypes

Hassan, T., Badr, M. A., Elsafy, U. R., Hesham, M., Sherief, L. M., & Zakaria, M. M. (2016) · InTech eBooks · doi:10.5772/64644 · Cited by 9 · see citing works

Serum non-transferrin-bound iron and low-density lipoprotein oxidation in heterozygous hemochromatosis

van Tits, L. J. H., Jacobs, E. M. G., Swinkels, D. W., Lemmers, H., van der Vleuten, G. M., Graaf, J. D., & Stalenhoef, A. F. H. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.04.100 · Cited by 9 · see citing works

Non-transferrin-bound iron determination in blood serum using microsequential injection solid phase spectrometry– proof of concept

Miranda, J. L. A., Mesquita, R. B. R., Leite, A., Silva, A. M. N., Rangel, M., & Rangel, A. O. S. S. (2023) · Talanta · doi:10.1016/j.talanta.2023.124345 · Cited by 8 · see citing works

Correlates of Hepcidin and NTBI according to HFE Status in Patients Referred to a Liver Centre

Ryan, E. M., Ryan, J. D., Russell, J. L., Coughlan, B., Tjalsma, H., Swinkels, D. W., Stewart, S. F., & Crowe, J. (2014) · Acta Haematologica · doi:10.1159/000363490 · Cited by 8 · see citing works

Estimation of Body Iron Stores

Worwood, M. (2011) · Humana Press eBooks · doi:10.1007/978-1-60327-485-2_25 · Cited by 7 · see citing works

Diagnostics: Markers of Body Iron Status

Girelli, D., Marchi, G., Busti, F., Chesini, F., & Castagna, A. (2025) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-92033-2_25 · Cited by 6 · see citing works

Quantification of non-transferrin bound iron (NTBI) in human serum by isotope dilution mass spectrometry (IDMS)

Yang, D., Ng, X. Q., & Walczyk, T. (2019) · Journal of Analytical Atomic Spectrometry · doi:10.1039/c9ja00142e · Cited by 6 · see citing works

Plasma Iron and Iron Delivery to the Tissues

Graham, R. M., Chua, A. C. G., & Trinder, D. (2011) · Humana Press eBooks · doi:10.1007/978-1-60327-485-2_7 · Cited by 6 · see citing works

Potential problems in the determination of serum non-transferrin-bound iron using nitrilotriacetic acid and ultrafiltration

Makino, T., Nakamura, K., & Takahara, K. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2013.10.006 · Cited by 5 · see citing works

Transfusion and Iron Chelation Therapy in Thalassemia and Sickle Cell Disease

Kwiatkowski, J. L., & Porter, J. B. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511596582.040 · Cited by 4 · see citing works

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Schümann, K., Ettle, T., Szegner, B., Elsenhans, B., & Solomons, N. W. (2013) · Perspectives in Medicine · doi:10.1016/j.permed.2013.09.003 · Cited by 4 · see citing works

The Effect of Daily Iron Supplementation with 60 mg Ferrous Sulfate for 12 Weeks on Non-Transferrin Bound Iron Concentrations in Women with a High Prevalence of Hemoglobinopathies

Steele, S. L., Kroeun, H., & Karakochuk, C. D. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020180 · Cited by 4 · see citing works

Clinical Use of Iron Chelators

Porter, J. B., & Hershko, C. (2011) · Humana Press eBooks · doi:10.1007/978-1-60327-485-2_28 · Cited by 4 · see citing works

Comparison of Bleomycin-Detectable Iron and Labile Plasma Iron Assays

Itkonen, O., Vaahtera, L., & Parkkinen, J. (2013) · Clinical Chemistry · doi:10.1373/clinchem.2013.205302 · Cited by 4 · see citing works

Considerations for the safe and effective use of iron interventions in areas of malaria burden

Namaste, S. M. L., & Raiten, D. J. (2009) · The FASEB Journal · doi:10.1096/fasebj.23.1_supplement.lb445 · Cited by 4 · see citing works

Indices of iron homeostasis in asymptomatic subjects with HFE mutations and moderate ferritin elevation during iron removal treatment

Infanti, L., Leitner, G. C., Moe, M. K., Pehlic, V., Benkert, P., Cattaneo, M., Holbro, A., Passweg, J. R., Worel, N., & Buser, A. S. (2022) · Blood Cells Molecules and Diseases · doi:10.1016/j.bcmd.2022.102689 · Cited by 2 · see citing works

Quantifying non-transferrin-bound iron (NTBI) in human plasma: incorporating BODIPY-pyridylhydrazone (BODIPY-PH) within a thin green film linked to a portable fluorescence-based device

Naksen, P., Chansaenpak, K., Jungsuttiwong, S., Intayot, R., Jakmunee, J., Pencharee, S., Lieberzeit, P. A., & Jarujamrus, P. (2024) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-024-05441-3 · Cited by 2 · see citing works

NTBI unveiled by chelatable fluorescent beads

Sebastiani, G., & Pantopoulos, K. (2014) · Biochemical Journal · doi:10.1042/bj20141083 · Cited by 2 · see citing works

"Aluminium Induces Iron-Mediated Oxidative Stress in Brain Tissue"

Vieželienė, D. (2022) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2022.42.006771 · Cited by 2 · see citing works

The role of free iron in cardiovascular diseases. Part II

Izzo, M., Gasbarro, V., & Coscia, V. (2017) · Journal of Theoretical and Applied Vascular Research · doi:10.24019/jtavr.35 · Cited by 2 · see citing works

Treatment of Systemic Iron Overload

Porter, J. B. (2016) · Royal Society of Chemistry eBooks · doi:10.1039/9781782623892-00106 · Cited by 1 · see citing works

Safety and efficacy of iron supplementation in pregnant Kenyan women

Mwangi, M. N. (2014) · doi:10.18174/304172 · Cited by 1 · see citing works

Intravenous iron therapy with ferric carboxymaltose results in a rapid and sustained rise in myocardial iron content through a non-canonical pathway: a translational studyPreprint

Vera‐Aviles, M., Kabir, S., Shah, A., Polzella, P., Lim, Y., Buckley, P., Ball, C., Swinkels, D. W., Matlung, H. L., Blans, C., et al. (2024) · medRxiv · doi:10.1101/2024.01.18.24301496 · Cited by 1 · see citing works

Studies on treatment of renal anemia in patients on chronic hemodialysis

Stefánsson, B. V. (2011) · Skemman

Relationships between iron, oxidative stress, glycated proteins and the development of atherosclerosis in Type 2 diabetes

Aljwaid, H. (2015) · PEARL (University of Plymouth) · doi:10.24382/2587

NEW APPROACHES TO THE TREATMENT OF HEMOGLOBINOPATHIES AND THALASSEMIA

Steinberg, M. H., Forget, B. G., Higgs, D. R., & Weatherall, D. J. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511596582.039

Pathogenesis and Management of Iron Overload in MDS

Hershko, C. (2011) · Springer eBooks · doi:10.1007/978-94-007-0440-4_12

Non-transferrin-bound iron assay system utilizing a conventional automated analyzer

Ito, S., Ikuta, K., Kato, D., Shibusa, K., Niizeki, N., Tanaka, H., Addo, L., Toki, Y., Hatayama, M., Inamura, J., et al. (2014) · Clinica Chimica Acta · doi:10.1016/j.cca.2014.07.013 · Cited by 18 · see citing works

Second international round robin for the quantification of serum non-transferrin-bound iron and labile plasma iron in patients with iron-overload disorders

de Swart, L., Hendriks, J. C. M., van der Vorm, L. N., Cabantchik, Z. I., Evans, P., Hod, E. A., Brittenham, G. M., Furman, Y., Wójczyk, B. S., Janssen, M. C. H., et al. (2015) · Haematologica · doi:10.3324/haematol.2015.133983 · Cited by 92 · see citing works

Quantification of Non-Transferrin-Bound Iron in the Presence of Unsaturated Transferrin

Gosriwatana, I., Loréal, O., Lu, S., Brissot, P., Porter, J. B., & Hider, R. C. (1999) · Analytical Biochemistry · doi:10.1006/abio.1999.4216 · Cited by 167 · see citing works

International Comparison Study of Toxic Iron Assays in Patients with Iron Overload Disorders

de Swart, L., Hendriks, J. C. M., van der Vorm, L. N., Cabantchik, I. Z., Evans, P., Hod, E. A., Brittenham, G. M., Furman, Y., Janssen, M. C. H., Biemond, B. J., et al. (2014) · Blood · doi:10.1182/blood.v124.21.4033.4033

Clinical and methodological factors affecting non-transferrin-bound iron values using a novel fluorescent bead assay

Garbowski, M., Ma, Y., Fucharoen, S., Srichairatanakool, S., Hider, R. C., & Porter, J. B. (2016) · Translational research · doi:10.1016/j.trsl.2016.05.005 · Cited by 18 · see citing works