The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity
Open accessAbstract
A novel perspective of the function of carotenoids and carotenoid-derived products - including, but not restricted to, the retinoids - is emerging in recent years which connects these compounds to the control of adipocyte biology and body fat accumulation, with implications for the management of obesity, diabetes and cardiovascular disease. Cell and animal studies indicate that carotenoids and carotenoids derivatives can reduce adiposity and impact key aspects of adipose tissue biology including adipocyte differentiation, hypertrophy, capacity for fatty acid oxidation and thermogenesis (including browning of white adipose tissue) and secretory function. Epidemiological studies in humans associate higher dietary intakes and serum levels of carotenoids with decreased adiposity. Specifically designed human intervention studies, though still sparse, indicate a beneficial effect of carotenoid supplementation in the accrual of abdominal adiposity. The objective of this review is to summarize recent findings in this area, place them in physiological contexts, and provide likely regulatory schemes whenever possible. The focus will be on the effects of carotenoids as nutritional regulators of adipose tissue biology and both animal and human studies, which support a role of carotenoids and retinoids in the prevention of abdominal adiposity.
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Cites
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Cited by
Bohn, T., Desmarchelier, C., El, S. N., Keijer, J., van Schothorst, E., Rühl, R., & Borel, P. (2019) · Proceedings of the Nutrition Society · doi:10.1017/s0029665118002641 · Cited by 156
Metadata
- Authors
- Luisa Bonet, M., Canas, J. A., Ribot, J., & Palou, A.
- Venue
- Archives of Biochemistry and Biophysics
- Publisher
- Elsevier BV
- Published
- 2015-04
- Volume
- 572
- Pages
- 112-125
- ISSN
- 0003-9861 (ISSN-L)
- OpenAlex
- W2013651825
- Cited by
- 221
- References
- 19
- FWCI
- 11.62
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Luisa Bonet, M., Canas, J. A., Ribot, J., & Palou, A. (2015). Carotenoids and their conversion products in the control of adipocyte function, adiposity and obesity. Archives of Biochemistry and Biophysics. https://doi.org/10.1016/j.abb.2015.02.022
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.