The DOI matches its Crossref record; 117 of the 120 references it cites were found in a registry or an index.
Polysaccharide-based antibiofilm surfaces
Abstract
Surface treatment by natural or modified polysaccharide polymers is a promising means to fight against implant-associated biofilm infections. The present review focuses on polysaccharide-based coatings that have been proposed over the last ten years to impede biofilm formation on material surfaces exposed to bacterial contamination. Anti-adhesive and bactericidal coatings are considered. Besides classical hydrophilic coatings based on hyaluronic acid and heparin, the promising anti-adhesive properties of the algal polysaccharide ulvan are underlined. Surface functionalization by antimicrobial chitosan and derivatives is extensively surveyed, in particular chitosan association with other polysaccharides in layer-by-layer assemblies to form both anti-adhesive and bactericidal coatings.Statement of significance Bacterial contamination of surfaces, leading to biofilm formation, is a major problem in fields as diverse as medicine, first, but also food and cosmetics. Many prophylactic strategies have emerged to try to eliminate or reduce bacterial adhesion and biofilm formation on surfaces of materials exposed to bacterial contamination, in particular implant materials. Polysaccharides are widely distributed in nature. A number of these natural polymers display antibiofilm properties. Hence, surface treatment by natural or modified polysaccharides is a promising means to fight against implant-associated biofilm infections. The present manuscript is an in-depth look at polysaccharide-based antibiofilm surfaces that have been proposed over the last ten years. This review, which is a novelty compared to published literature, will bring well documented and updated information to readers of Acta Biomaterialia.
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“As such, this EPS may have acted as an anionic surfactant and reduced the binding affinity of the tested bacteria to hydrocarbons [53].”
From Analysis of Chemical Structure and Antibiofilm Properties of Exopolysaccharides from Lactiplantibacillus plantarum EIR/IF-1 Postbiotics (2022) · cites this paper as [53]
Citations
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3 of the 120 references couldn’t be matched to a known paper.
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Targeting microbial biofilms: current and prospective therapeutic strategies
Koo, H., Allan, R. N., Howlin, R. P., Stoodley, P., & Hall‐Stoodley, L. (2017) · Nature Reviews Microbiology · doi:10.1038/nrmicro.2017.99 · Cited by 1,861
Natural Anti-biofilm Agents: Strategies to Control Biofilm-Forming Pathogens
Mishra, R., Panda, A. K., Mandal, S. D., Shakeel, M., Bisht, S. S., & Khan, J. A. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.566325 · Cited by 492
Wei, T., Yu, Q., & Chen, H. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201801381 · Cited by 462
The application of hyaluronic acid in bone regeneration
Zhai, P., Peng, X., Li, B., Liu, Y., Sun, H., & Li, X. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.10.169 · Cited by 438
Antibacterial hydrogel coating: Strategies in surface chemistry
Zhao, C., Zhou, L., Chiao, M., & Yang, W. (2020) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2020.102280 · Cited by 249
Metadata
- Authors
- Junter, G.-A., Thébault, P., & Lebrun, L.
- Affiliations
- Centre National de la Recherche Scientifique (FR)
- Corresponding author
- Junter, Guy-Alain
- Venue
- Acta Biomaterialia
- Publisher
- Elsevier BV
- Published
- 2016-01
- Volume
- 30
- Pages
- 13-25
- ISSN
- 1742-7061 (ISSN-L)
- OpenAlex
- W2153189401
- Cited by
- 215
- References
- 120
- Citations by year
- 2026: 12 · 2025: 14 · 2024: 17 · 2023: 8 · 2022: 26 · 2021: 27 · 2020: 24 · 2019: 27 · 2018: 27 · 2017: 22 · 2016: 11
- FWCI
- 1.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Biomaterialia (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Physical Sciences › Materials Science › Surfaces, Coatings and Films › Polymer Surface Interaction Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
- Keywords
- antibiofilm surfaces, polysaccharide coatings, bacterial adhesion, anti-adhesive coatings, bactericidal coatings, ulvan, chitosan, layer-by-layer assembly, hyaluronic acid, heparin, algal polysaccharides, surface functionalization
- MeSH terms
- Animals, Anti-Bacterial Agents, Humans, Bacterial Physiological Phenomena, Biofilms, Coated Materials, Biocompatible, Chitosan
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