The DOI matches its Crossref record; 135 of the 135 references it cites were found in a registry or an index.
PLA micro- and nano-particles
Open accessAbstract
Poly(D,L-lactic acid) (PLA) has been widely used for various biomedical applications for its biodegradable, biocompatible, and nontoxic properties. Various methods, such as emulsion, salting out, and precipitation, have been used to make better PLA micro and nano-particle formulations. They are widely used as controlled drug delivery systems of therapeutic molecules, including proteins, genes, vaccines, and anti-cancer drugs. Even though PLA-based particles have challenges to overcome, such as low drug loading capacity, low encapsulation efficiency, and terminal sterilization, continuous innovations in particulate formulations will lead to development of clinically useful formulations.
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Cites
1 retracted
Microencapsulation techniques, factors influencing encapsulation efficiency
Jyothi, N. V. N., Prasanna, P. M., Sakarkar, S. N., Prabha, K. S., Ramaiah, P. S., & Srawan, G. Y. (2010) · Journal of Microencapsulation · doi:10.3109/02652040903131301 · Cited by 731
RetractedPoly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier
Makadia, H. K., & Siegel, S. J. (2011) · Polymers · doi:10.3390/polym3031377 · Cited by 4,816 · cited 2×
“7 There are several techniques useful for the preparation of PLA-based micro and nanoparticles [21-28].”
PLGA-based nanoparticles: An overview of biomedical applications
Danhier, F., Ansorena, E., Silva, J. M., Coco, R., Le Breton, A., & Préat, V. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2012.01.043 · Cited by 3,806
Biodegradable polymeric nanoparticles as drug delivery devices
Soppimath, K. S., Aminabhavi, T. M., Kulkarni, A. R., & Rudzinski, W. E. (2001) · Journal of Controlled Release · doi:10.1016/s0168-3659(00)00339-4 · Cited by 3,549
Biodegradation and biocompatibility of PLA and PLGA microspheres
Anderson, J. M., & Shive, M. S. (1997) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(97)00048-3 · Cited by 2,617
An overview of the recent developments in polylactide (PLA) research
Madhavan Nampoothiri, K., Nair, N. R., & John, R. P. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.05.092 · Cited by 2,448
Jain, R. A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00115-0 · Cited by 2,214
Targeted polymeric therapeutic nanoparticles: design, development and clinical translation
Kamaly, N., Xiao, Z., Valencia, P. M., Radovic-Moreno, A. F., & Farokhzad, O. C. (2012) · Chemical Society Reviews · doi:10.1039/c2cs15344k · Cited by 1,730
Polymer nanoparticles: Preparation techniques and size-control parameters
Rao, J. P., & Geckeler, K. E. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.01.001 · Cited by 1,725
Overcoming the challenges in administering biopharmaceuticals: Formulation and delivery strategies
Mitragotri, S., Burke, P. A., & Langer, R. (2014) · Nature Reviews Drug Discovery · doi:10.1038/nrd4363 · Cited by 1,702
Cited by
Elmowafy, E. M., Tiboni, M., & Soliman, M. E. (2019) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-019-00439-x · Cited by 621
A Perspective on Polylactic Acid-Based Polymers Use for Nanoparticles Synthesis and Applications
Casalini, T., Rossi, F., Castrovinci, A., & Perale, G. (2019) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2019.00259 · Cited by 500
Systemic Review of Biodegradable Nanomaterials in Nanomedicine
Su, S., & Kang, P. M. (2020) · Nanomaterials · doi:10.3390/nano10040656 · Cited by 312
Star-shaped and branched polylactides: Synthesis, characterization, and properties
Michalski, A., Brzezinski, M., Lapienis, G., & Biela, T. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2018.10.004 · Cited by 158
Aliphatic Polyester-Based Biodegradable Microbeads for Sustainable Cosmetics
Nam, H. C., & Park, W. H. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.0c00017 · Cited by 29
Metadata
- Authors
- Lee, B. K., Yun, Y., & Park, K.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2016-12
- Volume
- 107
- Pages
- 176-191
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W2414230095
- Cited by
- 340
- References
- 135
- FWCI
- 1.66
- Type
- journal article
- Language
- en
- Open access
- green
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- Lee, B. K., Yun, Y., & Park, K. (2016). PLA micro- and nano-particles. Advanced Drug Delivery Reviews. https://doi.org/10.1016/j.addr.2016.05.020
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
