The DOI matches its Crossref record; 264 of the 266 references it cites were found in a registry or an index.
Optical biosensors: a decade in review
Open accessAbstract
Miniaturized, specific, rapid response and economical biosensors are finding applications in biotechnology, environmental studies, agriculture, food inspection and safety, disease diagnosis and medical utilities. Of the many categories of biosensors, optical biosensors have brought about an extra edge in sensing applications due to their selective, rapid and extremely sensitive measurements. Biosensors are analytical tools used to detect specific analytes such as cholesterol, urea, etc. having biomolecules such as nucleic acids, proteins, carbohydrates as key element for detecting these analytes along with a transducer and a data analysis and visualization tool. In case of optical biosensors the analyte is detected using light with either label based or label free techniques. In this paper some of the marked advances in the last decade in the field of optical biosensors have been reviewed with an emphasis on their fabrication approaches and growing application areas. Along with some of the carefully selected article on new developments in optical biosensors through the last decade, a brief historical review of optical biosensors since the breakthrough in optical biosensors in 1970s has also been presented. Another focus of the current review is the classification of biosensors, typical structures along with emerging developments in optical biosensing that are likely to impact the current decade. Major application areas and emerging applications through the last decade have been outlined to present a clear picture on the versatility of optical biosensors. Finally, the review also considers the challenges and future of emerging optical biosensing technologies in the current decade.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Label-based optical techniques are colorimetric or fluorometric methods [172] which have demonstrated great promise for monitoring of metabolites, glucose, and other biomarkers in sweat, tears, or interstitial fluid, providing valuable insights for disease management and preventive healthcare [173,174].”
From The emergence of AI-based wearable sensors for digital health technology: a review (2023) · cites this paper as [172]
In the citing paper
“Integration of these materials into flexible substrates and microfluidic devices has facilitated the development of wearable devices that are lightweight, conformable, and comfortable for long-term use [172].”
From The emergence of AI-based wearable sensors for digital health technology: a review (2023) · cites this paper as [172]
Citations
Cites
1 retracted
Bulbul, A. A.-M., Rahaman, H., & Podder, E. (2022) · Optical and Quantum Electronics · doi:10.1007/s11082-022-03513-1 · Cited by 15
RetractedSurface plasmon resonance for gas detection and biosensing
Liedberg, B., Nylander, C. I., & Lunström, I. (1983) · Sensors and Actuators · doi:10.1016/0250-6874(83)85036-7 · Cited by 2,545
Li, Z., Yi, Y., Luo, X., Xiong, N., Liu, Y., Li, S., Sun, R., Wang, Y., Hu, B., Chen, W., et al. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25727 · Cited by 1,823
Die Bestimmung optischer Konstanten von Metallen durch Anregung von Oberflächenplasmaschwingungen
Kretschmann, E. (1971) · Zeitschrift für Physik A Hadrons and Nuclei · doi:10.1007/bf01395428 · Cited by 1,697
Bhalla, N., Jolly, P., Formisano, N., & Estrela, P. (2016) · Essays in Biochemistry · doi:10.1042/ebc20150001 · Cited by 1,484
Surface Plasmon Resonance: A Versatile Technique for Biosensor Applications
Nguyen, H. H., Park, J., Kang, S., & Kim, M. (2015) · Sensors · doi:10.3390/s150510481 · Cited by 1,372
Damborský, P., Švitel, J., & Katrlı́k, J. (2016) · Essays in Biochemistry · doi:10.1042/ebc20150010 · Cited by 1,221
Handbook of Surface Plasmon Resonance
Kooyman, R. P. H., Corn, R. M., Wark, A. W., Lee, H. J., Gedig, E. T., Engbers, G. H. M., Walstrom, L., de Mol, N. J., Hall, D. R., Yager, P., et al. (2008) · Royal Society of Chemistry eBooks · doi:10.1039/9781847558220 · Cited by 856
Fiber-Optic Chemical Sensors and Biosensors (2015–2019)
Wang, X., & Wolfbeis, O. S. (2019) · Analytical Chemistry · doi:10.1021/acs.analchem.9b04708 · Cited by 836
Optical biosensors: an exhaustive and comprehensive review
Chen, C., & Wang, J. (2020) · The Analyst · doi:10.1039/c9an01998g · Cited by 791
Flagged first, then by citations
2 of the 266 references couldn’t be matched to a known paper.
Research works printed but not linked: 6
- Bansi Dhar Malhotra, 2018, Nanomaterials in biosensors: Fundamentals and applications, Nanomaterials for Biosensors, 1
- Singh, 2017, Surface plasmon resonance: a boon for viral diagnostics. Reference Module, Life Sci.
- Yogesh B. Gianchandani, Osamu Tabata, Hans P. Zappe, Comprehensive microsystems, volume 1. Elsevier Amsterdam, 2008.
- Kulkarni, 2020, Fabrication of enzyme-based optical biosensor for estimation of inorganic phosphate in a urine sample. SN, Applied Sciences, 2, 1
- Yinghui Chen. Upconversion nanoparticle based optical biosensor for the detection of molecular biomarkers. PhD thesis, School of Mathematical and Physical Sciences,Faculty of Science, University of Technology Sydney, 2019.
- Yaneva, 2019, Determination of n-methyl carbamates in a liver sample using an optical biosensor, Journal of Chemical Technology & Metallurgy, 54
Cited by
Sorted by citations
Items 101–200 of 292
Uniyal, A., Ansari, G., Kumba, K., Karki, B., & Pal, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-29162-3.00017-4 · Cited by 16
Vijayakumar, K., Subha, S., Anushkannan, N. K., Kaliaperumal, K., & Kumar, U. A. (2025) · Sensors International · doi:10.1016/j.sintl.2025.100351 · Cited by 15
Kalaipoonguzhali, V., Vijayakumar, R., Madhukumar, A. S., & Kumar, U. A. (2025) · Sensing and Imaging · doi:10.1007/s11220-025-00675-6 · Cited by 14
“These limitations are especially objectionable in distant or resource-poor environments as well as in circumstances where constant or recurrent water quality [17 , 18 ] evaluation is needed.”
Functionalized Antifouling Polymer Brushes for Biospecific Surfaces
Postma, E. J., Scheres, L., de Beer, S., Kuzmyn, A. R., & Zuilhof, H. T. (2025) · Advanced Materials Interfaces · doi:10.1002/admi.202400955 · Cited by 15
Solid-Phase Optical Sensing Techniques for Sensitive Virus Detection
Seymour, E. Ç., Kanık, F. E., Gür, S. D., Bakhshpour, M., Araz, A., Ünlü, N. L., & Ünlü, M. S. (2023) · Sensors · doi:10.3390/s23115018 · Cited by 13
Vidhya, S., Wekalao, J., & Reddy, G. R. (2025) · Plasmonics · doi:10.1007/s11468-025-03105-1 · Cited by 13
“Optical biosensors have emerged as promising candidates for non-invasive glucose monitoring due to their contact-less operational capability [13].”
Graphene-based biosensors in milk analysis: A review of recent developments
Bayrak, S., & Gergeroglu, H. (2023) · Food Chemistry · doi:10.1016/j.foodchem.2023.138257 · Cited by 12
Cañas, R. Z., Jaramillo-Flores, M., Vallejo-Ruíz, V., Macuil, R. D. D., & Gayou, V. L. (2024) · Biosensors · doi:10.3390/bios14010034 · Cited by 9
“Biosensors can be classified according to the transducer (optical, electrochemical, piezoelectric, etc.) or the BRE molecules (nucleic acids, proteins, enzymes, antibodies, cells, or biological tissues) [16,17].”
BackgroundUltra-sensitive graphene micro-ribbon integrated THz biosensor for breast cancer cell detection
Selvaraj, M., & Sreeja, B. S. (2025) · Methods · doi:10.1016/j.ymeth.2025.04.014 · Cited by 12
Taymour, N., Hassan, M. G., AlGhamdi, M. A., & Omara, W. S. (2025) · Prosthesis · doi:10.3390/prosthesis7030051 · Cited by 12
“A biosensor is an analytical device that is able to capture or entrap analyte in a certain medium and express the result of this process either optically [7], electrochemically [8], or physically [9,10].”
A Novel SPR Sensor Response for Chemical Sensing of Organic Solvents: A Computational Approach
Uniyal, A., Trabelsi, Y., Pal, A., Debnath, A., Vora, M. A., Ganesan, S., VERMA, V. K., Jayabalan, K., & Sharma, S. (2026) · Advanced Theory and Simulations · doi:10.1002/adts.202502113 · Cited by 11
Moreira, M. J., Pintado, M., & de Almeida, J. M. M. M. (2024) · Biosensors · doi:10.3390/bios14090423 · Cited by 11
Rodriguez-Nieves, A. L., Shah, S., Taylor, M. L., Alle, M., & Huang, X. (2025) · Nanomaterials · doi:10.3390/nano15040264 · Cited by 13
“These techniques depend on changes in the intensity, phase, wavelength shift, and angle of reflection [263,264].”
Bioconvergence: advancing biosensors with nanotechnology for real-time health monitoring
Mishra, R., Minocha, S., Goel, R., Gaur, P. K., Lata, K., & Singh, R. R. (2025) · Bulletin of the National Research Centre/Bulletin of the National Research Center · doi:10.1186/s42269-025-01308-4 · Cited by 11
“A gadget monitors the change in interactions after the sensor sends electromagnetic waves, where a region senses the light-matter interactions (Singh et al. 2023).”
Matar, Z. S., Noor, Z. Z., Alhindi, A., & Yuliarto, B. (2025) · Chemistry & Biodiversity · doi:10.1002/cbdv.202403451 · Cited by 11
“Optical biosensors are very effective tools used for the detection and analysis of various analytes, with extensive applications in biological research, healthcare, pharmaceuticals, agriculture, military and environmental monitoring [82].”
Nautiyal, D., & Jain, U. (2025) · Talanta Open · doi:10.1016/j.talo.2025.100430 · Cited by 11
Advances in Diagnostic Techniques for Influenza Virus Infection: A Comprehensive Review
Qian, Q., Fan, G., Yang, W., Shen, C., Yang, Y., Liu, Y., & Xiao, W. (2025) · Tropical Medicine and Infectious Disease · doi:10.3390/tropicalmed10060152 · Cited by 10
“Despite these technological advancements, practical implementation faces persistent challenges, including device stability optimization, cost-effective manufacturing processes, and the requirement for enhanced user interface design with improved mobile data integration capabilities [110].”
A Novel Approach to Realize Plasmonic Sensors via Multimode Optical Waveguides: A Review
Arcadio, F., Prete, D. D., Zeni, L., & Cennamo, N. (2023) · Sensors · doi:10.3390/s23125662 · Cited by 10
Geetha, B. T., Kumar, J. A., Arthy, M., Krithiga, T., Senthilkumar, G., Roomi, A. B., Shather, A. H., & Sillanpää, M. E. T. (2024) · Chemical Papers · doi:10.1007/s11696-024-03501-7 · Cited by 11
“…size range, responsivity, excellent sensitivity along with cost-effectiveness, thereby contributing its advancements in environmental application, food testing, agriculture, biotechnology, safety disease detection, as well as medical conservatives (Singh et al. 2023b; Singh et al. 2023a).”
Firouzi, F., Vahedi, A., & Haghipour, S. (2024) · Physica B Condensed Matter · doi:10.1016/j.physb.2024.416766 · Cited by 10
Ultrasensitive Terahertz Biodetection Using Metasensors Based on Parity-Time Symmetry
Liu, H., Ke, X., Shen, L., Zhang, Y., Cao, Y., Tian, L., Hou, D., & Zhang, G. (2024) · IEEE Transactions on Terahertz Science and Technology · doi:10.1109/tthz.2024.3496560 · Cited by 9
Paper-based biosensors—from fabrication to applications: a review
Thakur, A., Malik, V., & Gupta, D. (2024) · Chemical Papers · doi:10.1007/s11696-024-03804-9 · Cited by 9
Enhancing Evanescent Wave Coupling of Near-Surface Waveguides with Plasmonic Nanoparticles
Lapointe, J., Grégoire, A., Bérubé, J.-P., & Vallée, R. (2023) · Sensors · doi:10.3390/s23083945 · Cited by 9
“This is of great interest for robust and compact three-dimensional integrated photonic circuits for sensing applications such as greenhouse gases detection [26], water pollutants detection [27] and biosensors [28,29].”
BackgroundLi, R., Yu, L., Li, J., Li, W. W., Yang, F., Wang, J., & Xu, X. (2024) · Optics Express · doi:10.1364/oe.519015 · Cited by 8
Recent Trends in Hydrogel-Based Biosensor Technology for the Diagnosis of Neurodegenerative Diseases
Ayçiçek, S., Cevher, Ş. C., & Acar, S. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c00420 · Cited by 9
Plasmonic SPR biosensor with bayesian regression for non-invasive protein biomarker detection
Ahmed, A. M., Wekalao, J., Aljaafreh, M. J., Zoubi, W. A., Elsayed, H. A., Mehaney, A., & Rajakannu, A. (2025) · Scientific Reports · doi:10.1038/s41598-025-22949-5 · Cited by 8
Thakur, S., Kumari, M., Kumar, N., Kumar, S., Gandhi, S., Bhaduri, G. A., & Arun, R. K. (2024) · Springer eBooks · doi:10.1007/978-981-97-5473-1_4 · Cited by 8
Optical fibre long-period grating sensors modified with antifouling bio-functional nano-brushes
Vrabcová, M., Spasovová, M., Forinová, M., Giannetti, A. E., Houška, M., Lynn, N. S., Jr., Baldini, F., Kopeček, J., Chiavaioli, F. E., & Vaisocherová‐Lísalová, H. (2024) · Biomaterials Science · doi:10.1039/d4bm01447b · Cited by 7
Optical biosensors utilising viral receptors ACE2 and ACE2 mimics
Ow, S. Y., Sutarlie, L., Lim, S. W. Y., Salleh, N. A. B. M., Tanaka, Y., Tan, C. K. I., & Su, X. (2024) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2024.117630 · Cited by 7
Muslihati, A., Septiani, N. L. W., Gumilar, G., Nugraha, N., Wasisto, H. S., & Yuliarto, B. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c01965 · Cited by 7
Phage Biosensor for the Classification of Metastatic Urological Cancers from Urine
Juusti, V., Rannikko, A. S., Laurila, A., Sundvall, M., Hanninen, P. E., & Kulpakko, J. (2024) · Life · doi:10.3390/life14050600 · Cited by 7
“In recent years, biosensors with various biorecognition elements have garnered attention [16–18].”
BackgroundÇelik, H., Caf, B. B., & Çebi, G. (2024) · Indian Journal of Microbiology · doi:10.1007/s12088-024-01359-7 · Cited by 6
Vidya, C., Arun, A. P., Patra, S. M., Moses, V., Prashantha, K., & Mudhulu, S. (2025) · Ionics · doi:10.1007/s11581-025-06412-z · Cited by 7
“A study by Singh et al. (2023) emphasizes the synthesis and optimization of CNT-based sensors for a range of applications, outlining the benefits of using CNTs for biomolecule immobilization [265].”
Aliqab, K., Wekalao, J., Armghan, A., Alsharari, M., & Patel, S. K. (2025) · Ain Shams Engineering Journal · doi:10.1016/j.asej.2025.103749 · Cited by 6
Optical biosensors for detection of exosomes
Vafadar, A., Maleki, M., Ehtiati, S., Moghadam, H. Z., & Savardashtaki, A. (2025) · Clinica Chimica Acta · doi:10.1016/j.cca.2025.120704 · Cited by 7
Vijayakumar, K., Karthikeyan, S., Anandaram, H., Soumya, K. V., & Muheki, J. (2026) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2026.100968 · Cited by 6
Shati, A. A., Al-dolaimy, F., Alfaifi, M. Y., Sayyed, R. Z., Mansouri, S., Aminov, Z., Alubady, R., Gandla, K., Alawady, A. H. R., & Alsaalamy, A. H. (2023) · Microchemical Journal · doi:10.1016/j.microc.2023.109500 · Cited by 6
Forty years of advances in optical biosensors—are “autonomous” biosensors in our future?
Ligler, F. S., & Ligler, G. T. (2024) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-024-05338-1 · Cited by 6
Xiao, L., Singh, R., Nedoma, J., Wang, Q., Liu, F., Tosi, D., Marques, C., Zhang, B., & Kumar, S. (2024) · APL Photonics · doi:10.1063/5.0223660 · Cited by 6
Photonic silver iodide nanostructures for optical biosensors
Aslam, H., Nusrat, N., Mansour, M., Umar, A., Ullah, A., Honey, S., Sohail, M. J., Abbas, M., Aslam, M. W., & Khan, M. U. (2024) · Exploration of BioMat-X · doi:10.37349/ebmx.2024.00025 · Cited by 6
Wekalao, J., Al‐Rawi, M. B. A., Elhendi, A. Z., Mehaney, A., Elsayed, H. A. E. A., Abukhadra, M. R., Alqhtani, H. A., & Rajakannu, A. (2025) · Physica E Low-dimensional Systems and Nanostructures · doi:10.1016/j.physe.2025.116357 · Cited by 6
Lab-On-Chip for Liquid Biopsy: A New Approach for the Detection of Biochemical Targets
Ciminelli, C., Colapietro, P., Brunetti, G., & Armenise, M. N. (2023) · International Conference on Transparent Optical Networks · doi:10.1109/icton59386.2023.10207546 · Cited by 6
Introduction to nanotechnology
Sarwar, S., Raja, D. A., Hussain, D., Shah, M. R., & Malik, M. I. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95511-9.00012-3 · Cited by 6
Controllable and Flexible 4D Fabrication Strategy for Expandable Micro-Sensor Elements on the Fiber
Li, C.-X., Chen, Q., Li, X.-L., Qu, J., Liu, Y., & Qu, S.-L. (2025) · Journal of Lightwave Technology · doi:10.1109/jlt.2025.3543899 · Cited by 5
la Grasta, A., Gómez-Gómez, M., Griol, A., Gómez, E., Martı́nez, A., & Dell’Olio, F. (2025) · IEEE Sensors Journal · doi:10.1109/jsen.2025.3604239 · Cited by 5
“Sincethese interactions often involve proteins, nucleic acids, or disease-specific biomarkers, their precise characterization serves as a cornerstone for early diagnosis and the development of targeted therapies [1], [2], [3].”
Role of surface engineering in advancement of optoelectrochemical sensing platforms
divya, D. D., Singh, A., & Chandra, P. (2025) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2025.09.043 · Cited by 5
Wekalao, J., Mehaney, A., Salah, B., Abukhadra, M. R., Stefano Bellucci, A., Elsayed, H. A. E. A., & Rajakannu, A. (2025) · Frontiers in Physics · doi:10.3389/fphy.2025.1659054 · Cited by 5
Insulin Quantification Through Electrochemical and Optical Aptasensors: A Review
Chong, J. Q., Shakhih, M. F. M., Vijayam, B., Citartan, M., Ching, C. T., & Wahab, A. A. (2025) · Annals of Biomedical Engineering · doi:10.1007/s10439-025-03881-1 · Cited by 6
“SYBR green is an example of a fluorescence tag [99, 100].”
Biosensor-Based Platforms for the Detection and Screening of Mycobacterium leprae Infection
de Jesus, A. C. P., de Oliveira, A. L. G., Scala, F. D., Menezes, C. A. D. S., Bueno, L. L., van Grinsven, B., Arreguin-Campos, R., Fujiwara, R. T., & Cleij, T. J. (2026) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00851 · Cited by 5
Graphene-based nanomaterials-driven innovations in biosensors for cancer diagnosis
Zazoum, B., Panda, S., Wekalao, J., & Prakash, J. (2026) · Journal of Materials Science · doi:10.1007/s10853-026-12209-w · Cited by 5
“Biosensors have emerged as tools in addressing the shortcomings of conventional diagnostic approaches [6].”
Butt, M. A. (2026) · Materials Today · doi:10.1016/j.mattod.2026.103226 · Cited by 5
Su, Y., Zhang, Y., Zhao, Z., Du, Z., Lei, C., Yang, Q., Liu, N., Bai, R., Zhu, L., & Xu, W. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217831 · Cited by 5
Panciera, C., Brunetti, G., & Ciminelli, C. (2026) · Nanotechnology Reviews · doi:10.1515/ntrev-2025-0284 · Cited by 5
Research Trends in the Development of Block Copolymer-Based Biosensing Platforms
Chung, Y.-H., & Oh, J. K. (2024) · Biosensors · doi:10.3390/bios14110542 · Cited by 7
“…of the DNA detection was much higher within the porous structure of BPCs. Optical biosensors have the characteristic of using an optical converter in the signal measurement step and can perform highly selective, sensitive, and rapid measurements compared to other biosensing platforms [69,128].”
Recent advances of optical and electrochemical (bio)sensors for doping agents detection in sport
Hsu, C.-Y., Kadheem, M., Kanjariya, P., Rajiv, A., Karim, M. M., Shankhyan, A., Albert, H. M., Jain, B., & Dehghanipour, M. (2025) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2025.03.009 · Cited by 5
Mahajan, P., & Khanna, V. (2025) · Journal of environmental chemical engineering · doi:10.1016/j.jece.2025.117388 · Cited by 5
Makarov, R., Qaid, M. R. T. M., Alhussein, A. N. D., Valeev, B. I., Agliullin, T. A., Anfinogentov, V., & Sakhabutdinov, A. (2024) · Optics · doi:10.3390/opt5020016 · Cited by 6
“The development of fiber-optic sensing technologies opens up new opportunities to improve patient care, health status and quality of life [17], in particular in the field of new more sensitive and accurate fiber-optic temperature sensors.”
BackgroundDaneshgar, H., Fatahi, Y., Salehi, G., Bagherzadeh, M., & Rabiee, N. (2024) · Analytica Chimica Acta · doi:10.1016/j.aca.2024.343534 · Cited by 5
Optical Fiber Mediated Biosensors for Multiplex and Onsite Food Safety Analysis: A Review
Hameed, S., Naz, I., Badea, M., Bano, N., Andreescu, S., Hayat, A., & Jubeen, F. (2025) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/ada97b · Cited by 5
Shen, Y., Shi, Y., & Wang, J. (2025) · Lab on a Chip · doi:10.1039/d5lc00450k · Cited by 6
Shatar, L., Pillai, N., Chee, H., Mustafa, F. H., Nasir, M. N. M., Zakaria, R. B., Mustafa, M. K., Zain, M. N. M., & Suhailin, F. H. (2025) · Applied Spectroscopy Reviews · doi:10.1080/05704928.2025.2530703 · Cited by 6
Shaver, A., Mallires, K. R., Harris, J., Kavner, J., Wang, B., Gottlieb, R., Lión‐Villar, J., Herranz, M. Á., Martı́n, N., & Arroyo‐Currás, N. (2023) · ACS Applied Polymer Materials · doi:10.1021/acsapm.3c02206 · Cited by 5
Monfared, Y. E., & Qasymeh, M. (2024) · Plasmonics · doi:10.1007/s11468-024-02402-5 · Cited by 5
“Noninvasive and in situ detection and monitoring of biological analytes in real time and with a high accuracy is a trending research area and important subject matter which attracted a lot of attention from both academia and industry in recent years [1, 2].”
Kaura, R., Dhillon, H. S., Thakur, N., Singla, M., Goraya, R. K., & Sinha, C. (2025) · Methods and protocols in food science · doi:10.1007/978-1-0716-4787-5_7 · Cited by 4
Photonic Crystal Fiber-Based Chemical and Bacterial Sensors for Healthcare Applications: A Review
Patel, P., Kumar, D., Chaudhary, V. S., Kumari, S., Tiwari, R. K., & Kumar, S. (2025) · IEEE Sensors Journal · doi:10.1109/jsen.2025.3624370 · Cited by 4
“One of the newest developments is computationally generated peptides, which are particularly helpful for wearable sensors that can detect analytes like cortisol [74], [75], [76].”
Othman, S. I., Mehaney, A., Ahmed, A. M., Elsayed, H. A., Rajakannu, A., Wekalao, J., Vijayalakshmi, K., & Stefano Bellucci, A. (2025) · AIP Advances · doi:10.1063/5.0294011 · Cited by 4
Wekalao, J., Elsayed, H. A., Mehaney, A., Alfassam, H. E., Abukhadra, M. R., Zoubi, W. A., Rajakannu, A., & Hajjiah, A. (2025) · AIP Advances · doi:10.1063/5.0284585 · Cited by 4
Wang, B., Tian, Y., Zhang, Z., Kai, T., Xiang, J., Wu, P., & Ding, P. (2025) · The Analyst · doi:10.1039/d5an00910c · Cited by 4
Ghosh, S., Sahoo, J., & Singh, K. (2026) · Experimental Eye Research · doi:10.1016/j.exer.2026.111004 · Cited by 4
Rishi, P., Kuzhaloli, S., Manimegalai, R., Ram, C. S., & Anushkannan, N. K. (2026) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2026.101020 · Cited by 5
Enhanced urine refractive index sensing using a defect-engineered one-dimensional photonic crystal
Aly, A. H. (2026) · Scientific Reports · doi:10.1038/s41598-026-58385-2 · Cited by 4
“In parallel, recent progress in photonic biosensing, including integrated photonic systems and data-assisted sensing strategies, has further expanded the possibilities for improving device performance and supporting real-time biomedical diagnostics 22–25 .”
Fire up Biosensor Technology to Assess the Vitality of Trees after Wildfires
Touloupakis, E., Moia, I. C., Zampieri, R. M., Cocozza, C., Frassinelli, N., Marchi, E., Foderi, C., Lorenzo, T. D., Rezaie, N., Muzzini, V. G., et al. (2024) · Biosensors · doi:10.3390/bios14080373 · Cited by 4
Seliem, Y., & Abdellatif, S. O. (2024) · Applied Optics · doi:10.1364/ao.533267 · Cited by 4
Chugh, P., Soni, S., Chahar, M., Ghanghas, N., & Mohan, H. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-21658-9.02004-0 · Cited by 3
Shalileh, F., Hosseini, M., Golbashy, M., Dadmehr, M., Sabahi, H., Xu, C., Fu, L., & Karimi‐Maleh, H. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.115628 · Cited by 3
Feng, Y., Sun, L., Wang, Z., Sun, J., Zhang, J., & Zhao, Y. (2025) · Allergy medicine. · doi:10.1016/j.allmed.2025.100079 · Cited by 3
Micro‐ and Nano‐Scaled Microbial Electrochemical Biosensing
Wu, X., Zhang, J., Hu, M., Wei, W., Wei, T., & Gao, T. (2025) · Small Methods · doi:10.1002/smtd.202501370 · Cited by 4
“An optical signal is a widely employed signal output method in microbial biosensors [ 27 ].”
Kamani, T., Patel, S. K., Baz, A., & Kumar, O. P. (2026) · IEEE photonics journal · doi:10.1109/jphot.2026.3657765 · Cited by 3
“It’s attributed to the reason that one sensor may simultaneously recognize signals from several kinds of sensors [4].”
Akimsha, R., Basuru, P., Sharmilan, T., & Wanniarachchi, D. C. (2026) · Food Control · doi:10.1016/j.foodcont.2026.112093 · Cited by 3
Sen, L., & Mukhopadhyay, B. (2024) · Plasmonics · doi:10.1007/s11468-024-02494-z · Cited by 3
“At present, optical-based biosensors are widely used in bioanalytical research [10, 11], drug discovery, and medical diagnostics [12, 13], due to the multiple characteristics of absorption, transmittance, and reflectance of light waves for the change in the surrounding medium [14–16].”
Mehandiratta, G., & Kaler, R. S. (2024) · Journal of Modern Optics · doi:10.1080/09500340.2024.2439379 · Cited by 3
“These sensors exhibit high sensitivity and efficiency in terms of time, cost and accuracy [ 5 , 6 ].”
Shibina, T., Sreejith, T., Nithyaja, B., & Pramod, K. S. (2025) · Optik · doi:10.1016/j.ijleo.2025.172508 · Cited by 3
Selvi, R. S., Murugesan, R. R., Wekalao, J., & Rajakannu, A. (2025) · Plasmonics · doi:10.1007/s11468-025-03178-y · Cited by 3
Modeling and Simulation of a High-Performance Magnetic Biosensor for Biomedical Sensing
Husseini, A. A., Yahya, K., & Di̇ri̇can, O. (2024) · Ergonomics International Journal · doi:10.23880/eoij-16000322 · Cited by 3
Biosensors for amplification-free viral RNA detection
Parassol, B. G., Takeuti, N. N. K., Faria, H. A. M., Jorge, K. C., Sampaio, I., Zucolotto, V., & Vieira, N. C. S. (2024) · Biosensors and Bioelectronics X · doi:10.1016/j.biosx.2024.100478 · Cited by 3
Ultrasensitive detection of interleukin-6 enabled by three-dimensional spatial amplification
Yamaguchi, M., & Shetty, V. (2024) · Sensors and Actuators Reports · doi:10.1016/j.snr.2024.100213 · Cited by 3
Development of an Ultra-Sensitive Magnetic-Based Biosensor; a Simulation Study
Yahya, K. A., Husseini, A. A., Di̇ri̇can, O., Attar, H. H., Aldababsa, M., & Hafez, M. M. (2023) · International Engineering Conference on Electrical, Energy, and Artificial Intelligence (EICEEAI) · doi:10.1109/eiceeai60672.2023.10590267 · Cited by 3
“On the other hand, optical biosensors offer high selectivity and low background signals, but they require sophisticated equipment and are often expensive [6], [7].”
BackgroundBrief Overview of Different Biosensors: Properties, Applications, and Their Role in Chemistry
Suma, B. P., & Adarakatti, P. S. (2024) · Royal Society of Chemistry eBooks · doi:10.1039/9781837676323-00001 · Cited by 3
Future electrodes for sepsis detection: digital microfluidic biosensors from plant waste
Prathaban, S. N., Zambry, N. S., Ibrahim, F., Ahmad, M. Y., Jamaluddin, N. F., & Tee, T. S. (2024) · Microfluidics and Nanofluidics · doi:10.1007/s10404-024-02771-7 · Cited by 2
Sustainability of Biosensors Over Conventional Methods
Erkmen, C., Taghvimi, A., Javadzadeh, Y., & Kurbanoğlu, S. (2024) · Royal Society of Chemistry eBooks · doi:10.1039/9781837676323-00420 · Cited by 2
Smartphone‐Powered Pdot Biosensors for Quantitative Phenylketonuria Screening at the Point of Care
Zeng, Z., Dai, Y., Deng, S., Liu, Z.-H., Feng, R., Shi, X., Zhan, Z., Tian, B., Dong, Z., Men, X., et al. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202502040 · Cited by 2
Highly sensitive bi-layer interferometer on an optical fiber tip for label-free biosensing purposes
Martychowiec, A., Kwietniewski, N., Janik, M., Szostak, S., Koba, M., & Smietana, M. J. (2025) · Measurement · doi:10.1016/j.measurement.2025.119391 · Cited by 2
Nano-engineered biomimetic materials: toward point-of-care diagnosis of infectious diseases
Baharlouei, Z., Aminjavaheri, S., Vajhadin, F., Nejatbakhsh, M. M., Sarshar, F. Z., Vali, H., Karimzadeh, F., Sanati, A., & Presley, J. F. (2025) · Microchimica Acta · doi:10.1007/s00604-025-07637-5 · Cited by 2
“Optical biosensors are currently being explored for the development of diagnostic tests, including colorimetric, fluorescence, SPR, and photoelectrochemical (PEC) techniques [87, 96, 102–108].”
Recent advances in nucleic acid-based biosensors for bacterial pathogen detection
Singh, R. R., Tigga, J. G., Kosma, S., & Patel, M. K. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.116435 · Cited by 2
Deepak, J., Nadar, N. R., Sharma, S., Krushna, B. R. R., Kumar, S., Kumari, B. N., Mishra, S., Sargunam, B., Pruthviraj, I. S., Nagabhushana, H., et al. (2025) · Materials Science and Engineering B · doi:10.1016/j.mseb.2025.119133 · Cited by 2
Yang, J., Bai, Y., Yang, J., Yang, C., Ye, P., Gao, S., Shi, J., & Guan, C. (2026) · Optics & Laser Technology · doi:10.1016/j.optlastec.2026.114754 · Cited by 2
Hamzah, A. E., Sapiee, N. M., Hamzah, M. E., Fadhel, M. M., Huddin, A. B., Al-Shareeda, M. A., Mohamad, H., Abushagur, A. A. G., Arsad, N., Ali, S. H. M., et al. (2026) · Optical Fiber Technology · doi:10.1016/j.yofte.2026.104580 · Cited by 2
Karadurmuş, L., Çetinkaya, A., Kocabay, P., Jaballah, M. B., Baldrich, E., & Özkan, S. A. (2026) · Microchimica Acta · doi:10.1007/s00604-026-08026-2 · Cited by 2
“Optical biosensors detect variations in specific optical char - acteristics, such as absorption, fluorescence, or refractive index at the transducer’s surface, produced when a target analyte comes in contact with a respective bioreceptor [19, 79–81].”
System architecture control design and clinical translation in closed-loop drug delivery
Qin, W., Cui, Y., Wang, H., Zhang, Y., & Cheng, Z. (2026) · Materials Today Chemistry · doi:10.1016/j.mtchem.2026.103601 · Cited by 2
Influence of Ion Exchange Process Parameters on Broadband Differential Interference
Gut, K., & Błahut, M. (2023) · Sensors · doi:10.3390/s23136092 · Cited by 2
Metadata
- Authors
- Singh, A. K., Mittal, S., Das, M., Saharia, A., & Tiwari, M.
- Affiliations
- Manipal University Jaipur (IN)
- Vellore Institute of Technology University (IN)
- Corresponding author
- Tiwari, Manish
- Venue
- Alexandria Engineering Journal
- Publisher
- Elsevier BV
- Published
- 2023-03
- Volume
- 67
- Pages
- 673-691
- ISSN
- 1110-0168 (ISSN-L)
- OpenAlex
- W4320474624
- Cited by
- 292
- References
- 266
- Citations by year
- 2026: 64 · 2025: 108 · 2024: 87 · 2023: 33
- FWCI
- 26.02
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Alexandria Engineering Journal (publishedVersion, cc-by-nc-nd)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical Chemistry and Sensors
- Keywords
- optical biosensors, biosensor fabrication, label-free detection, biosensor classification, biosensor applications, biosensor miniaturization, disease diagnosis, food safety, environmental monitoring
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
