The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Medication adherence: A call for action
Open accessAbstract
Poor adherence to efficacious cardiovascular-related medications has led to considerable morbidity, mortality, and avoidable health care costs. This article provides results of a recent think-tank meeting in which various stakeholder groups representing key experts from consumers, community health providers, the academic community, decision-making government officials (Food and Drug Administration, National Institutes of Health, etc), and industry scientists met to evaluate the current status of medication adherence and provide recommendations for improving outcomes. Below, we review the magnitude of the problem of medication adherence, prevalence, impact, and cost. We then summarize proven effective approaches and conclude with a discussion of recommendations to address this growing and significant public health issue of medication nonadherence.
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“Adherence is better in patients recruited to clinical trials compared with those treated in the real world.455,456”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [455]
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Citations
Cites
1 retracted
Retracted: Predictive Validity of a Medication Adherence Measure in an Outpatient Setting
Morisky, D. E., Ang, A., Krousel‐Wood, M., & Ward, H. J. (2008) · The Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2008.07572.x · Cited by 2,877
RetractedCrossing the Quality Chasm: A New Health System for the 21st Century
Baker, A. (2001) · BMJ · doi:10.1136/bmj.323.7322.1192 · Cited by 10,779
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
Adherence to Long-Term Therapies: Evidence for Action
Geest, S. D., & Sabate, E. J. (2003) · European Journal of Cardiovascular Nursing · doi:10.1016/s1474-5151(03)00091-4 · Cited by 6,310
Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence
Morisky, D. E., Green, L. W., & Levine, D. M. (1986) · Medical Care · doi:10.1097/00005650-198601000-00007 · Cited by 5,399
Kirk, J. M. W., MacDonald, A., Lavender, P., Dean, J. M., & Rubin, G. (2017) · Biomedicine Hub · doi:10.1159/000480347 · Cited by 3,902
Update on Key Emerging Challenges in Cystic Fibrosis
Jennings, M. T., Riekert, K. A., & Boyle, M. (2014) · Medical Principles and Practice · doi:10.1159/000357646 · Cited by 3,671
Health Literacy: A Prescription to End Confusion
Committee on Health Literacy, Board on Neuroscience and Behavioral Health, & Institute of Medicine (2004) · doi:10.17226/10883 · Cited by 3,444
Patient-centredness: a conceptual framework and review of the empirical literature
Mead, N., & Bower, P. (2000) · Social Science & Medicine · doi:10.1016/s0277-9536(00)00098-8 · Cited by 2,993
Interventions for enhancing medication adherence
Nieuwlaat, R., Wilczynski, N., Navarro, T., Hobson, N., Jeffery, R., Keepanasseril, A., Agoritsas, T., Mistry, N., Iorio, A., Jack, S., et al. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000011.pub4 · Cited by 2,945
Research works printed but not linked: 1
- Flack, 1996, Benefits of adherence to antihypertensive drug therapy, Eur Soc Cardiol, 17, 16
Cited by
Sorted by citations
Kirk, J. M. W., MacDonald, A., Lavender, P., Dean, J. M., & Rubin, G. (2017) · Biomedicine Hub · doi:10.1159/000480347 · Cited by 3,902
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.018 · Cited by 1,582
Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences
Chowdhury, R., Khan, H., Heydon, E., Shroufi, A., Fahimi, S., Moore, C., Stricker, B., Mendis, S., Hofman, A., Mant, J., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht295 · Cited by 931
National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
Jacobson, T. A., Maki, K. C., Orringer, C. E., Jones, P. H., Kris-Etherton, P., Sikand, G., La Forge, R., Daniels, S. R., Wilson, D. P., Morris, P. B., et al. (2015) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.09.002 · Cited by 784
Metadata
- Authors
- Bosworth, H. B., Granger, B. B., Mendys, P., Brindis, R., Burkholder, R., Czajkowski, S. M., Daniel, J. G., Ekman, I., Ho, M., Johnson, M., Kimmel, S. E., Liu, L. Z., Musaus, J., Shrank, W. H., Buono, E. W., Weiss, K., & Granger, C. B.
- Affiliations
- Duke University (US)
- University of North Carolina at Chapel Hill (US)
- American College of Cardiology (US)
- National Consumers League (US)
- National Institutes of Health (US)
- United States Department of Health and Human Services (US)
- University of Gothenburg (SE)
- University of Pennsylvania (US)
- Pfizer (United States) (US)
- Brigham and Women's Hospital (US)
- United States Food and Drug Administration (US)
- Corresponding author
- Bosworth, Hayden B.
- ORCID
- Venue
- American Heart Journal
- Publisher
- Elsevier BV
- Published
- 2011-09
- Volume
- 162
- Issue
- 3
- Pages
- 412-424
- ISSN
- 0002-8703 (ISSN-L)
- PMC
- PMC3947508
- OpenAlex
- W2072773013
- Cited by
- 448
- References
- 83
- Citations by year
- 2026: 20 · 2025: 30 · 2024: 21 · 2023: 18 · 2022: 30 · 2021: 35 · 2020: 25 · 2019: 41 · 2018: 40 · 2017: 46 · 2016: 36 · 2015: 30 · 2014: 29 · 2013: 26 · 2012: 19
- FWCI
- 21.83
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- VA HSRD (RCS 08-027)
- American Heart Association
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
- Keywords
- medication adherence, medication non-adherence, cardiovascular drugs, health care costs, morbidity and mortality, stakeholder recommendations, public health policy, community health providers
- MeSH terms
- Cardiovascular Agents, Cardiovascular Diseases, Community Health Services, Community Pharmacy Services, Fees, Pharmaceutical, Humans, Morbidity, United States, Survival Rate, Drug Costs, Drug Monitoring
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