Cited by 448Medication Adherence and CompliancePharmacy and Medical PracticesAtrial Fibrillation Management and Outcomes

The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.

Medication adherence: A call for action

Open access

Bosworth, Hayden B., Granger, Bradi B., Mendys, Phil, Brindis, Ralph, Burkholder, Rebecca, Czajkowski, Susan M., Daniel, Jodi G., Ekman, Inger, Ho, Michael, Johnson, Mimi, Kimmel, Stephen E., Liu, Larry Z., Musaus, John, Shrank, William H., Buono, Elizabeth Whalley, Weiss, Karen, Granger, Christopher B.·2011·American Heart Journal

DOI 10.1016/j.ahj.2011.06.007PMC PMC3947508

Open this paper in CoChat — free account

Abstract

Poor adherence to efficacious cardiovascular-related medications has led to considerable morbidity, mortality, and avoidable health care costs. This article provides results of a recent think-tank meeting in which various stakeholder groups representing key experts from consumers, community health providers, the academic community, decision-making government officials (Food and Drug Administration, National Institutes of Health, etc), and industry scientists met to evaluate the current status of medication adherence and provide recommendations for improving outcomes. Below, we review the magnitude of the problem of medication adherence, prevalence, impact, and cost. We then summarize proven effective approaches and conclude with a discussion of recommendations to address this growing and significant public health issue of medication nonadherence.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1016/j.ahj.2011.06.007

Cites

84 of 84 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

1 retracted

Retracted: Predictive Validity of a Medication Adherence Measure in an Outpatient Setting
Morisky, D. E., Ang, A., Krousel‐Wood, M., & Ward, H. J. (2008) · The Journal of Clinical Hypertension · doi:10.1111/j.1751-7176.2008.07572.x · Cited by 2,877
Retracted
Crossing the Quality Chasm: A New Health System for the 21st Century
Baker, A. (2001) · BMJ · doi:10.1136/bmj.323.7322.1192 · Cited by 10,779
Adherence to medication.
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
Adherence to Long-Term Therapies: Evidence for Action
Geest, S. D., & Sabate, E. J. (2003) · European Journal of Cardiovascular Nursing · doi:10.1016/s1474-5151(03)00091-4 · Cited by 6,310
Concurrent and Predictive Validity of a Self-reported Measure of Medication Adherence
Morisky, D. E., Green, L. W., & Levine, D. M. (1986) · Medical Care · doi:10.1097/00005650-198601000-00007 · Cited by 5,399
Can Treatment Adherence Be Improved by Using Rubin's Four Tendencies Framework to Understand a Patient's Response to Expectations
Kirk, J. M. W., MacDonald, A., Lavender, P., Dean, J. M., & Rubin, G. (2017) · Biomedicine Hub · doi:10.1159/000480347 · Cited by 3,902
Update on Key Emerging Challenges in Cystic Fibrosis
Jennings, M. T., Riekert, K. A., & Boyle, M. (2014) · Medical Principles and Practice · doi:10.1159/000357646 · Cited by 3,671
Health Literacy: A Prescription to End Confusion
Committee on Health Literacy, Board on Neuroscience and Behavioral Health, & Institute of Medicine (2004) · doi:10.17226/10883 · Cited by 3,444
Patient-centredness: a conceptual framework and review of the empirical literature
Mead, N., & Bower, P. (2000) · Social Science & Medicine · doi:10.1016/s0277-9536(00)00098-8 · Cited by 2,993
Interventions for enhancing medication adherence
Nieuwlaat, R., Wilczynski, N., Navarro, T., Hobson, N., Jeffery, R., Keepanasseril, A., Agoritsas, T., Mistry, N., Iorio, A., Jack, S., et al. (2014) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000011.pub4 · Cited by 2,945

Flagged first, then by citations

Show all 83 references

Research works printed but not linked: 1

Flack, 1996, Benefits of adherence to antihypertensive drug therapy, Eur Soc Cardiol, 17, 16

Sorted by citations

Can Treatment Adherence Be Improved by Using Rubin's Four Tendencies Framework to Understand a Patient's Response to Expectations
Kirk, J. M. W., MacDonald, A., Lavender, P., Dean, J. M., & Rubin, G. (2017) · Biomedicine Hub · doi:10.1159/000480347 · Cited by 3,902
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw272 · Cited by 3,162
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I., De Backer, G., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2016.08.018 · Cited by 1,582
Adherence to cardiovascular therapy: a meta-analysis of prevalence and clinical consequences
Chowdhury, R., Khan, H., Heydon, E., Shroufi, A., Fahimi, S., Moore, C., Stricker, B., Mendis, S., Hofman, A., Mant, J., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht295 · Cited by 931
National Lipid Association Recommendations for Patient-Centered Management of Dyslipidemia: Part 2
Jacobson, T. A., Maki, K. C., Orringer, C. E., Jones, P. H., Kris-Etherton, P., Sikand, G., La Forge, R., Daniels, S. R., Wilson, D. P., Morris, P. B., et al. (2015) · Journal of Clinical Lipidology · doi:10.1016/j.jacl.2015.09.002 · Cited by 784
Adherence and health care costs
McGuire, M., & Iuga, A. O. (2014) · Risk Management and Healthcare Policy · doi:10.2147/rmhp.s19801 · Cited by 779
ESC/EAS Guidelines for the management of dyslipidaemias
Catapano, A. L., Reiner, Ž., De Backer, G., Graham, I., Taskinen, M.-R., Wiklund, O., Agewall, S., Alegria, E., Chapman, M. J., Durrington, P., et al. (2011) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2011.06.028 · Cited by 706
Emerging Role of Precision Medicine in Cardiovascular Disease
Leopold, J. A., & Loscalzo, J. (2018) · Circulation Research · doi:10.1161/circresaha.117.310782 · Cited by 380
Doing no harm in mindfulness-based programs: Conceptual issues and empirical findings
Baer, R., Crane, C., Miller, E., & Kuyken, W. (2019) · Clinical Psychology Review · doi:10.1016/j.cpr.2019.01.001 · Cited by 307
The Unmet Challenge of Medication Nonadherence
Kleinsinger, F. (2018) · The Permanente Journal · doi:10.7812/tpp/18-033 · Cited by 274
A text messaging intervention to promote medication adherence for patients with coronary heart disease: A randomized controlled trial
Park, L. G., Howie‐Esquivel, J., Chung, M. L., & Dracup, K. (2013) · Patient Education and Counseling · doi:10.1016/j.pec.2013.10.027 · Cited by 223
Treatment adherence in hemophilia
Thornburg, C. D., & Duncan, N. (2017) · Patient Preference and Adherence · doi:10.2147/ppa.s139851 · Cited by 196
eHealth in the future of medications management: personalisation, monitoring and adherence
Car, J., Tan, W. S., Huang, Z., Sloot, P., & Franklin, B. D. (2017) · BMC Medicine · doi:10.1186/s12916-017-0838-0 · Cited by 179
I Diretriz Brasileira de Prevenção Cardiovascular
Simão, A., Précoma, D., Andrade, J., Filho, H. C., Saraiva, J., Oliveira, G., Murro, A., Campos, A., Alessi, A., Avezum, Á., et al. (2013) · Arquivos Brasileiros de Cardiologia · doi:10.5935/abc.2013s012 · Cited by 186
A quantitative systematic review of the efficacy of mobile phone interventions to improve medication adherence
Park, L. G., Howie‐Esquivel, J., & Dracup, K. (2014) · Journal of Advanced Nursing · doi:10.1111/jan.12400 · Cited by 166
Improving Medication Adherence in Cardiometabolic Disease
Ferdinand, K. C., Senatore, F. F., Clayton‐Jeter, H. D., Cryer, D. R., Lewin, J. C., Nasser, S. A., Fiuzat, M., & Califf, R. M. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.11.034 · Cited by 166
Rethinking adherence: a health literacy—informed model of medication self-management
Bailey, S. C., Oramasionwu, C. U., & Wolf, M. S. (2013) · Journal of Health Communication · doi:10.1080/10810730.2013.825672 · Cited by 160
CDC Grand Rounds: Improving Medication Adherence for Chronic Disease Management — Innovations and Opportunities
Neiman, A. B., Ruppar, T. M., Ho, P. M., Garber, L., Weidle, P. J., Hong, Y., George, M. G., & Thorpe, P. (2017) · MMWR Morbidity and Mortality Weekly Report · doi:10.15585/mmwr.mm6645a2 · Cited by 158
Understanding Medication Nonadherence after Kidney Transplant
Nevins, T. E., Nickerson, P. W., & Dew, M. A. (2017) · Journal of the American Society of Nephrology · doi:10.1681/asn.2017020216 · Cited by 159
A systematic review and meta‐analysis on the effectiveness of education on medication adherence for patients with hypertension, hyperlipidaemia and diabetes
Tan, J. P., Cheng, K. K. F., & Siah, C. J. R. (2019) · Journal of Advanced Nursing · doi:10.1111/jan.14025 · Cited by 158
Relationship between depression and medication adherence in cardiovascular disease: the perfect challenge for the integrated care team
Goldstein, C. M., Gathright, E. C., & Garcia, S. (2017) · Patient Preference and Adherence · doi:10.2147/ppa.s127277 · Cited by 138
2022 Prevention of chronic non-communicable diseases in Of the Russian Federation. National guidelines
Drapkina, O. M., Васильевна, К. А., Калинина, А. М., Avdeev, S. M., Викторович, А. М., Alexandrova, L. M., Анциферова, А. А., Dm, A., Ахмеджанов, Н. М., Balanova, Y. А., et al. (2022) · CARDIOVASCULAR THERAPY AND PREVENTION · doi:10.15829/1728-8800-2022-3235 · Cited by 197
Effect of Electronic Reminders, Financial Incentives, and Social Support on Outcomes After Myocardial Infarction
Volpp, K. G. M., Troxel, A. B., Mehta, S. J., Norton, L. A., Zhu, J., Lim, R., Wang, W., Marcus, N., Terwiesch, C., Caldarella, K. L., et al. (2017) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2017.2449 · Cited by 130
The impact of medication adherence on clinical outcomes of coronary artery disease: A meta-analysis
Du, L., Cheng, Z., Zhang, Y., Li, Y., & Mei, D. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317695628 · Cited by 130
Bimatoprost Sustained-Release Implants for Glaucoma Therapy: 6-Month Results From a Phase I/II Clinical Trial
Lewis, R. A., Christie, W. C., Day, D. G., Craven, E. R., Walters, T., Bejanian, M., Lee, S. S., Goodkin, M. L., Zhang, J., Whitcup, S. M., et al. (2016) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2016.11.020 · Cited by 124
Longitudinal association between medication adherence and glycaemic control in Type 2 diabetes
Aikens, J. E., & Piette, J. D. (2012) · Diabetic Medicine · doi:10.1111/dme.12046 · Cited by 123
US trends in premature heart disease mortality over the past 50 years: Where do we go from here?
Ritchey, M. D., Wall, H. K., George, M. G., & Wright, J. S. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.09.005 · Cited by 119
Adherence to Pharmacological Smoking Cessation Interventions: A Literature Review and Synthesis of Correlates and Barriers
Pacek, L. R., McClernon, F. J., & Bosworth, H. B. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntx210 · Cited by 107
Factors associated with poor adherence to medication among hypertensive patients in twelve low and middle income Sub-Saharan countries
de Terline, D. M., Kane, A. D., Kramoh, K. E., Toure, I. A., Mipinda, J. B., Diop, I. B., Nhavoto, C., Balde, D. M., Ferreira, B., Houénassi, M., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0219266 · Cited by 102
Cardiometabolic Comorbidities in Cancer Survivors
Zullig, L. L., Sung, A. D., Khouri, M. G., Jazowski, S. A., Shah, N. P., Sitlinger, A. P., Blalock, D. V., Whitney, C. A., Kikuchi, R., Bosworth, H. B., et al. (2022) · JACC CardioOncology · doi:10.1016/j.jaccao.2022.03.005 · Cited by 105
Improving adherence to multiple medications in older people in primary care: Selecting intervention components to address patient‐reported barriers and facilitators
Patton, D., Cadogan, C. A., Ryan, C. A., Francis, J., Gormley, G., Passmore, P., Kerse, N. M., & Hughes, C. M. (2017) · Health Expectations · doi:10.1111/hex.12595 · Cited by 96
Combination pharmacotherapy to prevent cardiovascular disease: present status and challenges
Working Group on the Summit on Combination Therapy for CVD (2013) · European Heart Journal · doi:10.1093/eurheartj/eht407 · Cited by 91
Effect of Medication Co-payment Vouchers on P2Y12 Inhibitor Use and Major Adverse Cardiovascular Events Among Patients With Myocardial Infarction
Wang, T. Y., Kaltenbach, L. A., Cannon, C. P., Fonarow, G. C., Choudhry, N. K., Henry, T. D., Cohen, D. J., Bhandary, D., Khan, N. D., Anstrom, K. J., et al. (2019) · JAMA · doi:10.1001/jama.2018.19791 · Cited by 87
Systematic review, meta‐analysis and meta‐regression to determine the effects of patient education on health behaviour change in adults diagnosed with coronary heart disease
Shi, W., Ghisi, G. L. D. M., Zhang, L., Hyun, K. K., Pakosh, M. T., & Gallagher, R. D. (2022) · Journal of Clinical Nursing · doi:10.1111/jocn.16519 · Cited by 98
Medication adherence: Importance, issues and policy: A policy statement from the American Heart Association
Piña, I. L., Palo, K. E. D., Brown, M. T., Choudhry, N. K., Cvengros, J. A., Whalen, D., Whitsel, L. P., & Johnson, J. C. (2020) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2020.08.003 · Cited by 96
How to Screen for Non-Adherence to Antihypertensive Therapy
Gupta, P., Patel, P., Horne, R., Buchanan, H., Williams, B., & Tomaszewski, M. (2016) · Current Hypertension Reports · doi:10.1007/s11906-016-0697-7 · Cited by 84
Effect of Out‐of‐Pocket Cost on Medication Initiation, Adherence, and Persistence among Patients with Type 2 Diabetes: The Diabetes Study of Northern California (DISTANCE)
Karter, A. J., Parker, M. M., Solomon, M. D., Lyles, C. R., Adams, A. S., Moffet, H. H., & Reed, M. (2017) · Health Services Research · doi:10.1111/1475-6773.12700 · Cited by 82
Concordance of Adherence Measurement Using Self-Reported Adherence Questionnaires and Medication Monitoring Devices: An Updated Review
Monnette, A. M., Zhang, Y., Shao, H., & Shi, L. (2017) · PharmacoEconomics · doi:10.1007/s40273-017-0570-9 · Cited by 84
The potential impact of pharmacogenetic testing on medication adherence
Haga, S. B., & LaPointe, N. M. A. (2013) · The Pharmacogenomics Journal · doi:10.1038/tpj.2013.33 · Cited by 77
Use of Medications for Secondary Prevention After Coronary Bypass Surgery Compared With Percutaneous Coronary Intervention
Hlatky, M. A., Solomon, M. D., Shilane, D. A., Leong, T. K., Brindis, R. G., & Go, A. S. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.10.018 · Cited by 76
Recommendations for Providers on Person-Centered Approaches to Assess and Improve Medication Adherence
Bosworth, H. B., Fortmann, S. P., Kuntz, J. L., Zullig, L. L., Mendys, P., Safford, M. M., Phansalkar, S., Wang, T. S., & Rumptz, M. H. (2016) · Journal of General Internal Medicine · doi:10.1007/s11606-016-3851-7 · Cited by 81
Pharmacist-nurse collaborations in medication adherence-enhancing interventions: A review
Dotta-Celio, J., Ninane, F., Bugnon, O., & Schneider, M. P. (2018) · Patient Education and Counseling · doi:10.1016/j.pec.2018.01.022 · Cited by 70
The influence of patients’ knowledge on adherence to their chronic medications: a cross-sectional study in Jordan
Awwad, O., Akour, A. A., AlMuhaissen, S. A., & Morisky, D. E. (2015) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-015-0086-3 · Cited by 70
Understanding Barriers and Design Opportunities to Improve Healthcare and QOL for Older Adults through Voice Assistants
Chen, C., Johnson, J. G., Charles, K., Lee, A., Lifset, E. T., Hogarth, M., Moore, A. A., Farcas, E., & Weibel, N. (2021) · Proceedings of the 23rd International ACM SIGACCESS Conference on Computers and Accessibility · doi:10.1145/3441852.3471218 · Cited by 67
Electronic Measurement of Medication Adherence
Park, L. G., Howie‐Esquivel, J., & Dracup, K. (2014) · Western Journal of Nursing Research · doi:10.1177/0193945914524492 · Cited by 65
A Smartphone-based Medication Self-management System with Real-time Medication Monitoring
Hayakawa, M., Uchimura, Y., Omae, K., Waki, K., Fujita, H., & Ohe, K. (2013) · Applied Clinical Informatics · doi:10.4338/aci-2012-10-ra-0045 · Cited by 67
MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol
Santo, K., Chow, C. K., Thiagalingam, A., Rogers, K. D., Chalmers, J. P., & Redfern, J. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-017540 · Cited by 63
New oral anticoagulants: discussion on monitoring and adherence should start now!
Cate, H. T. (2013) · Thrombosis Journal · doi:10.1186/1477-9560-11-8 · Cited by 61
Adherence with cardiovascular medications and the outcomes in patients with coronary arterial disease: “Real‐world” evidence
Chen, C., Li, X., Su, Y., You, Z., Wan, R., & Hong, K. (2022) · Clinical Cardiology · doi:10.1002/clc.23898 · Cited by 66
Personalized Multimorbidity Management for Patients with Type 2 Diabetes Using Reinforcement Learning of Electronic Health Records
Zheng, H., Ryzhov, I. O., Xie, W., & Zhong, J. (2021) · Drugs · doi:10.1007/s40265-020-01435-4 · Cited by 60
Psychosocial factors and medication adherence among patients with coronary heart disease: A text messaging intervention
Park, L. G., Howie‐Esquivel, J., Whooley, M. A., & Dracup, K. (2014) · European Journal of Cardiovascular Nursing · doi:10.1177/1474515114537024 · Cited by 63
Patient-centered priorities for improving medication management and adherence
McMullen, C. K., Safford, M. M., Bosworth, H. B., Phansalkar, S., Leong, A., Fagan, M. B., Trontell, A., Rumptz, M., Vandermeer, M. L., Brinkman, W. B., et al. (2015) · Patient Education and Counseling · doi:10.1016/j.pec.2014.09.015 · Cited by 58
Quantitative determination of atenolol in dried blood spot samples by LC–HRMS: A potential method for assessing medication adherence
Lawson, G., Cocks, E., & Tanna, S. (2012) · Journal of Chromatography B · doi:10.1016/j.jchromb.2012.04.013 · Cited by 56
Impediments to Adherence to Post Myocardial Infarction Medications
Desai, N. R., & Choudhry, N. K. (2012) · Current Cardiology Reports · doi:10.1007/s11886-012-0322-6 · Cited by 51
CDC Grand Rounds: Improving medication adherence for chronic disease management — Innovations and opportunities
Neiman, A. B., Ruppar, T. M., Ho, P. M., Garber, L., Weidle, P. J., Hong, Y., George, M. G., & Thorpe, P. (2018) · American Journal of Transplantation · doi:10.1111/ajt.14649 · Cited by 52
Medication Adherence Interventions for Cardiovascular Disease in Low- and Middle-Income Countries: A Systematic Review
Ogungbe, O., Byiringiro, S., Adedokun-Afolayan, A., Seal, S. M., Himmelfarb, C. D., Davidson, P. M., & Commodore-Mensah, Y. Y. (2021) · Patient Preference and Adherence · doi:10.2147/ppa.s296280 · Cited by 54
PRescriptiOn PattERns of Oral Anticoagulants in Nonvalvular Atrial Fibrillation (PROPER study)
Başaran, Ö., Başaran, N. F., Çekiç, E. G., Altun, İ., Doğan, V., Mert, G. Ö., Mert, K. U., Akın, F., Soylu, M., Sancar, K. M., et al. (2015) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/1076029615614395 · Cited by 51
Motivating Patient Adherence to Allergic Rhinitis Treatments
Bender, B. G. (2015) · Current Allergy and Asthma Reports · doi:10.1007/s11882-014-0507-8 · Cited by 48
Pitfalls of medication adherence approximation through EHR and pharmacy records: Definitions, data and computation
Galozy, A., Nowaczyk, S., Sant’Anna, A., Ohlsson, M., & Lingman, M. (2020) · International Journal of Medical Informatics · doi:10.1016/j.ijmedinf.2020.104092 · Cited by 47
Understanding Medication Nonadherence from Social Media: A Sentiment-Enriched Deep Learning Approach
Xie, J., Liu, X., Zeng, D. D., & Fang, X. (2017) · MIS Quarterly · doi:10.25300/misq/2022/15336 · Cited by 50
Providing patients with pharmacogenetic test results affects adherence to statin therapy: results of the Additional KIF6 Risk Offers Better Adherence to Statins (AKROBATS) trial
Charland, S. L., Agatep, B. C., Herrera, V., Schrader, B. J., Frueh, F. W., Ryvkin, M., Shabbeer, J., Devlin, J. J., Superko, H. R., & Stanek, E. J. (2013) · The Pharmacogenomics Journal · doi:10.1038/tpj.2013.27 · Cited by 47
Feasibility and Preliminary Outcomes of a Web and Smartphone–Based Medication Self-Management Platform for Chronically Ill Patients
Anglada-Martínez, H., Martín-Conde, M., Rovira-Illamola, M., Sotoca-Momblona, J. M., Aymar, E. S., Aragunde, V., Moreno, M. A., Catalán, M., & Codina‐Jané, C. (2016) · Journal of Medical Systems · doi:10.1007/s10916-016-0456-y · Cited by 45
Sleep Quality, Short-Term and Long-Term CPAP Adherence
Somiah, M., Taxin, Z. H., Keating, J. M., Mooney, A. M., Norman, R. G., Rapoport, D. M., & Ayappa, I. A. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2138 · Cited by 46
Understanding the predictors of medication adherence: applying temporal self-regulation theory
Liddelow, C., Mullan, B. A., & Boyes, M. E. (2020) · Psychology and Health · doi:10.1080/08870446.2020.1788715 · Cited by 49
The Special Challenge of Nonadherence With Sublingual Immunotherapy
Bender, B. G., & Oppenheimer, J. J. (2014) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2014.01.003 · Cited by 45
Top 10 cardiovascular therapies and interventions for the next decade
Fuster, V. (2014) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2014.137 · Cited by 45
Improving adherence to medication for secondary cardiovascular disease prevention
Keenan, J. (2017) · European Journal of Preventive Cardiology · doi:10.1177/2047487317708145 · Cited by 43
Quality Assessment of Medical Apps that Target Medication-Related Problems
Loy, J. S., Ali, E. E., & Yap, K. Y. (2016) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2016.22.10.1124 · Cited by 44
2016 ESC/EAS Guidelines for the Management of Dyslipidaemias
Catapano, A. L., Graham, I. M., Backer, G. D., Wiklund, O., Chapman, M. J., Drexel, H., Hoes, A. W., Jennings, C. S., Landmesser, U., Pedersen, T. R., et al. (2016) · Kardiologia Polska · doi:10.5603/kp.2016.0157 · Cited by 48
The effectiveness of therapeutic patient education on adherence to oral anti-cancer medicines in adult cancer patients in ambulatory care settings: a systematic review
Arthurs, G., Simpson, J., Brown, A., Kyaw, O., Shyrier, S., & Concert, C. M. (2015) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2015-2057 · Cited by 41
Bisoprolol, ramipril and simvastatin determination in dried blood spot samples using LC–HRMS for assessing medication adherence
Lawson, G., Cocks, E., & Tanna, S. (2013) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2013.04.002 · Cited by 40
A systematic review of the inclusion of mechanisms of action in NIH-funded intervention trials to improve medication adherence
Edmondson, D., Falzon, L., Sundquist, K. J., Julian, J., Meli, L., Sumner, J. A., & Kronish, I. M. (2018) · Behaviour Research and Therapy · doi:10.1016/j.brat.2017.10.001 · Cited by 39
Cardiac rehabilitation in older adults: Apropos yet significantly underutilized
Lutz, A. H., & Forman, D. E. (2022) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2022.01.001 · Cited by 43
Infographics or video; which one is more effective in asthmatic patients’ health? a randomized clinical trial
Ebrahimabadi, M., Rezaei, K., Moini, A., Fournier, A., & Abedi, A. (2018) · Journal of Asthma · doi:10.1080/02770903.2018.1536143 · Cited by 37
Current prescription of prophylactic factor infusions and perceived adherence for children and adolescents with haemophilia: a survey of haemophilia healthcare professionals in the United States
Thornburg, C. D., Carpenter, S. L., Zappa, S. C., Munn, J. E., & Leissinger, C. (2012) · Haemophilia · doi:10.1111/j.1365-2516.2012.02756.x · Cited by 37
Life-long antimicrobial therapy: where is the evidence?
Lau, J. S. Y., Korman, T. M., & Woolley, I. J. (2018) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dky174 · Cited by 36
Patient-Reported Medication Adherence Barriers Among Patients with Cardiovascular Risk Factors
Zullig, L. L., Stechuchak, K. M., Goldstein, K. M., Olsen, M. K., McCant, F., Danus, S. M., Crowley, M. J., Oddone, E. Ž., & Bosworth, H. B. (2015) · Journal of Managed Care & Specialty Pharmacy · doi:10.18553/jmcp.2015.21.6.479 · Cited by 36
Disparities in Heart Failure and other Cardiovascular Diseases among Women
McSweeney, J. C., Bricker, C., Lefler, L. L., & Heo, S. (2012) · Women s Health · doi:10.2217/whe.12.22 · Cited by 40
Improving Medication Adherence and Health Care Outcomes in a Commercial Population through a Community Pharmacy
Akinbosoye, O. E., Taitel, M. S., Grana, J. R., Hill, J. C., & Wade, R. L. (2016) · Population Health Management · doi:10.1089/pop.2015.0176 · Cited by 39
Smart design of patient-centric long-acting products: from preclinical to marketed pipeline trends and opportunities
Bassand, C., Villois, A., Gianola, L., Laue, G., Ramazani, F., Riebesehl, B. U., Sánchez-Félix, M., Sedo, K., Ullrich, T., & Romić, M. D. (2022) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2022.2106213 · Cited by 35
Randomized Controlled Pilot Trial of a Low-Touch Remotely-Delivered Values Intervention to Promote Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors
Arch, J. J., Crespi, C. M., Levin, M. E., Genung, S. R., Nealis, M., Mitchell, J. L., Bright, E. E., Albright, K., Magidson, J. F., & Stanton, A. L. (2022) · Annals of Behavioral Medicine · doi:10.1093/abm/kaab118 · Cited by 34
Medication adherence part two: Predictors of nonadherence and adherence
Wheeler, K. J., Roberts, M. E., & Neiheisel, M. B. (2014) · Journal of the American Association of Nurse Practitioners · doi:10.1002/2327-6924.12105 · Cited by 39
Reduction in 2-Year Recurrent Risk Score and Improved Behavioral Outcomes After Participation in the “Beating Heart Problems” Self-management Program
Murphy, B. M., Worcester, M. C., Higgins, R. O., Elliott, P. C., Grande, M. R. L., Mitchell, F., Navaratnam, H. S., Turner, A., Grigg, L., Tatoulis, J., et al. (2013) · Journal of Cardiopulmonary Rehabilitation and Prevention · doi:10.1097/hcr.0b013e31828c7812 · Cited by 34
Medication adherence and its predictors among patients with heart failure
Shafipour, V., Amininasab, S. S., Lolaty, H. Â., & Moosazadeh, M. (2018) · Nursing and Midwifery Studies · doi:10.4103/nms.nms_9_17 · Cited by 36
Evaluation of medication adherence in chronic disease at a federally qualified health center
Oung, A. B., Kosirog, E. R., Chavez, B., Brunner, J. M., & Saseen, J. J. (2017) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622317714966 · Cited by 33
PARC report: A Health-Systems Focus on Reimbursement and Patient Access to Pharmacogenomics Testing
Rogers, S. L., Keeling, N. J., Giri, J., Gonzaludo, N., Jones, J. S., Glogowski, E., & Formea, C. M. (2020) · Pharmacogenomics · doi:10.2217/pgs-2019-0192 · Cited by 32
The effect of a decision aid intervention on decision making about coronary heart disease risk reduction: secondary analyses of a randomized trial
Sheridan, S., Draeger, L. B., Pignone, M. P., Rimer, B. K., Bangdiwala, S. I., Cai, J., Gizlice, Z., Keyserling, T. C., & Simpson, R. J. (2014) · BMC Medical Informatics and Decision Making · doi:10.1186/1472-6947-14-14 · Cited by 32
Prediction and pattern analysis of medication refill adherence through electronic health records and dispensation data
Galozy, A., & Nowaczyk, S. (2020) · Journal of Biomedical Informatics · doi:10.1016/j.yjbinx.2020.100075 · Cited by 31
Reinforcing Adherence to Antihypertensive Medications
Petry, N. M., Alessi, S. M., Byrne, S. A., & White, W. B. (2014) · Journal of Clinical Hypertension · doi:10.1111/jch.12441 · Cited by 31
Dose-dispensing service as an intervention to improve adherence to polymedication
Hersberger, K. E., Boeni, F., & Arnet, I. (2013) · Expert Review of Clinical Pharmacology · doi:10.1586/17512433.2013.811829 · Cited by 31
Objective quantification of adherence to prophylaxis in haemophilia patients aged 12 to 25years and its potential association with bleeding episodes
Pérez-Robles, T., Romero-Garrido, J. A., Rodriguez-Merchan, E. C., & Herrero-Ambrosio, A. (2016) · Thrombosis Research · doi:10.1016/j.thromres.2016.04.015 · Cited by 30
Better Medications Adherence Lowers Cardiovascular Events, Stroke, and All-Cause Mortality Risk: A Dose-Response Meta-Analysis
Liu, M., Zheng, G., Cao, X., Chang, X., Zhang, N., Liang, G., Wang, A., Yu, Y. P., Yang, Y., Zhao, Y., et al. (2021) · Journal of Cardiovascular Development and Disease · doi:10.3390/jcdd8110146 · Cited by 30
Clinical trials and systematic reviews addressing similar interventions for the same condition do not consider similar outcomes to be important: a case study in HIV/AIDS
Saldanha, I. J., Li, T., Yang, P., Owczarzak, J., Williamson, P. R., & Dickersin, K. (2017) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2017.02.005 · Cited by 28
Understanding if, how and why non-adherent decisions are made in an Australian community sample: A key to sustaining medication adherence in chronic disease?
Laba, T., Lehnbom, E. C., Brien, J.-A. E., & Jan, S. (2014) · Research in Social and Administrative Pharmacy · doi:10.1016/j.sapharm.2014.06.006 · Cited by 30
The prevalence of medication nonadherence in post-myocardial infarction survivors and its perceived barriers and psychological correlates: a cross-sectional study in a cardiac health facility in Malaysia
Ganasegeran, K., & Rashid, A. (2017) · Patient Preference and Adherence · doi:10.2147/ppa.s151053 · Cited by 28
Psychometric Evaluation of Chinese Version of Adherence to Refills and Medications Scale (ARMS) and Blood-Pressure Control Among Elderly with Hypertension
Chen, Y.-J., Chang, J., & Yang, S.-Y. (2020) · Patient Preference and Adherence · doi:10.2147/ppa.s236268 · Cited by 29
Aiming at strategies for a complex problem of medical nonadherence.
Castellano, J., Copeland-Halperin, R., & Fuster, V. (2013) · Global Heart · doi:10.1016/j.gheart.2013.06.001 · Cited by 36
The effectiveness of a nursing discharge programme to improve medication adherence and patient satisfaction in the psychiatric intensive care unit
Virgolesi, M., Pucciarelli, G., Colantoni, A. M., D'Andrea, F., Donato, B. D., Giorgi, F., Landi, L., Salustri, E., Turci, C., & Proietti, M. G. (2017) · Journal of Clinical Nursing · doi:10.1111/jocn.13776 · Cited by 29
Clinical Effectiveness of Hydralazine–Isosorbide Dinitrate in African-American Patients With Heart Failure
Ziaeian, B., Fonarow, G. C., & Heidenreich, P. A. (2017) · JACC Heart Failure · doi:10.1016/j.jchf.2017.04.008 · Cited by 28
Echocardiographic screening for rheumatic heart disease in 4 515 Sudanese school children: marked disparity between two communities
Ali, S., Domi, S. B., Abbo, B., Abbas, R., Bushari, T. M., Awad, K. A., Elhassan, A. A., & Abdel‐Rahman, M. E. (2018) · Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa · doi:10.5830/cvja-2018-022 · Cited by 28

Authors: Bosworth, H. B., Granger, B. B., Mendys, P., Brindis, R., Burkholder, R., Czajkowski, S. M., Daniel, J. G., Ekman, I., Ho, M., Johnson, M., Kimmel, S. E., Liu, L. Z., Musaus, J., Shrank, W. H., Buono, E. W., Weiss, K., & Granger, C. B.
Affiliations: Duke University (US)
University of North Carolina at Chapel Hill (US)
American College of Cardiology (US)
National Consumers League (US)
National Institutes of Health (US)
United States Department of Health and Human Services (US)
University of Gothenburg (SE)
University of Pennsylvania (US)
Pfizer (United States) (US)
Brigham and Women's Hospital (US)
United States Food and Drug Administration (US)
Corresponding author: Bosworth, Hayden B.
ORCID: Bosworth, Hayden B.
Granger, Bradi B.
Mendys, Phil
Brindis, Ralph
Czajkowski, Susan M.
Ekman, Inger
Kimmel, Stephen E.
Liu, Larry Z.
Granger, Christopher B.
Venue: American Heart Journal
Publisher: Elsevier BV
Published: 2011-09
Volume: 162
Issue: 3
Pages: 412-424
ISSN: 0002-8703 (ISSN-L)
DOI: 10.1016/j.ahj.2011.06.007
PMC: PMC3947508
OpenAlex: W2072773013
Cited by: 448
References: 83
Citations by year: 2026: 20 · 2025: 30 · 2024: 21 · 2023: 18 · 2022: 30 · 2021: 35 · 2020: 25 · 2019: 41 · 2018: 40 · 2017: 46 · 2016: 36 · 2015: 30 · 2014: 29 · 2013: 26 · 2012: 19
FWCI: 21.83
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: American Heart Journal (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
UNC Libraries
Funders: VA HSRD (RCS 08-027)
American Heart Association
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords: medication adherence, medication non-adherence, cardiovascular drugs, health care costs, morbidity and mortality, stakeholder recommendations, public health policy, community health providers
MeSH terms: Cardiovascular Agents, Cardiovascular Diseases, Community Health Services, Community Pharmacy Services, Fees, Pharmaceutical, Humans, Morbidity, United States, Survival Rate, Drug Costs, Drug Monitoring

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Medication adherence: A call for action

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks