Cited by 448Medication Adherence and CompliancePharmacy and Medical PracticesAtrial Fibrillation Management and Outcomes

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Medication adherence: A call for action

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Bosworth, Hayden B., Granger, Bradi B., Mendys, Phil, Brindis, Ralph, Burkholder, Rebecca, Czajkowski, Susan M., Daniel, Jodi G., Ekman, Inger, Ho, Michael, Johnson, Mimi, Kimmel, Stephen E., Liu, Larry Z., Musaus, John, Shrank, William H., Buono, Elizabeth Whalley, Weiss, Karen, Granger, Christopher B.·2011·American Heart Journal

DOI 10.1016/j.ahj.2011.06.007PMC PMC3947508

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Abstract

Poor adherence to efficacious cardiovascular-related medications has led to considerable morbidity, mortality, and avoidable health care costs. This article provides results of a recent think-tank meeting in which various stakeholder groups representing key experts from consumers, community health providers, the academic community, decision-making government officials (Food and Drug Administration, National Institutes of Health, etc), and industry scientists met to evaluate the current status of medication adherence and provide recommendations for improving outcomes. Below, we review the magnitude of the problem of medication adherence, prevalence, impact, and cost. We then summarize proven effective approaches and conclude with a discussion of recommendations to address this growing and significant public health issue of medication nonadherence.

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Authors: Bosworth, H. B., Granger, B. B., Mendys, P., Brindis, R., Burkholder, R., Czajkowski, S. M., Daniel, J. G., Ekman, I., Ho, M., Johnson, M., Kimmel, S. E., Liu, L. Z., Musaus, J., Shrank, W. H., Buono, E. W., Weiss, K., & Granger, C. B.
Affiliations: Duke University (US)
University of North Carolina at Chapel Hill (US)
American College of Cardiology (US)
National Consumers League (US)
National Institutes of Health (US)
United States Department of Health and Human Services (US)
University of Gothenburg (SE)
University of Pennsylvania (US)
Pfizer (United States) (US)
Brigham and Women's Hospital (US)
United States Food and Drug Administration (US)
Corresponding author: Bosworth, Hayden B.
ORCID: Bosworth, Hayden B.
Granger, Bradi B.
Mendys, Phil
Brindis, Ralph
Czajkowski, Susan M.
Ekman, Inger
Kimmel, Stephen E.
Liu, Larry Z.
Granger, Christopher B.
Venue: American Heart Journal
Publisher: Elsevier BV
Published: 2011-09
Volume: 162
Issue: 3
Pages: 412-424
ISSN: 0002-8703 (ISSN-L)
DOI: 10.1016/j.ahj.2011.06.007
PMC: PMC3947508
OpenAlex: W2072773013
Cited by: 448
References: 83
Citations by year: 2026: 20 · 2025: 30 · 2024: 21 · 2023: 18 · 2022: 30 · 2021: 35 · 2020: 25 · 2019: 41 · 2018: 40 · 2017: 46 · 2016: 36 · 2015: 30 · 2014: 29 · 2013: 26 · 2012: 19
FWCI: 21.83
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: American Heart Journal (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
UNC Libraries
Funders: VA HSRD (RCS 08-027)
American Heart Association
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Keywords: medication adherence, medication non-adherence, cardiovascular drugs, health care costs, morbidity and mortality, stakeholder recommendations, public health policy, community health providers
MeSH terms: Cardiovascular Agents, Cardiovascular Diseases, Community Health Services, Community Pharmacy Services, Fees, Pharmaceutical, Humans, Morbidity, United States, Survival Rate, Drug Costs, Drug Monitoring

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Medication adherence: A call for action

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