The DOI matches its Crossref record; 57 of the 58 references it cites were found in a registry or an index.
Association between periodontitis and arterial hypertension: A systematic review and meta-analysis
Abstract
Background Several studies have shown that periodontal diseases are associated with hypertension (HT). However, heterogeneity among populations, diagnosis criteria, and shared risk factors represent some difficulties in terms of interpretation. Therefore, the aim of this study was to determine the magnitude of the association between periodontal diseases and HT.Methods and results A systematic review and meta-analysis, including studies published up to June 2016, have been performed. Sixteen studies assessing the association between periodontal diseases and HT have been included. The meta-analysis considering all included studies (moderate to severe periodontitis) showed that the presence of HT was associated with the presence of periodontal diseases (OR, 1.50; 95% CI, 1.27-1.78). To reduce potential bias, a stratified analysis has been performed illustrating the impact of inclusion criteria and adjustments on the magnitude of the association. Interestingly, when only studies with secure diagnosis of severe periodontitis and HT were considered, an OR=1.64 (95% CI, 1.23-2.19) has been measured.Conclusions Periodontal diseases are associated with a higher risk of HT especially for severe periodontitis. However, no conclusions could be made regarding the causative involvement of periodontal diseases mainly due to the reduced number of available prospective studies and remaining questions regarding underlying biological mechanisms.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The magnitude of association between periodontitis and hypertension reported in this review (OR 1.22-1.53) is in agreement with that recently reported.27”
From Periodontitis is associated with hypertension: a systematic review and meta-analysis (2020) · cites this paper as [27]
Citations
Cites
Chobanian, A. V. (2003) · JAMA · doi:10.1001/jama.289.19.2560 · Cited by 25,386
2013 ESH/ESC Guidelines for the management of arterial hypertension
Authors Task Force Members, Mancia, G., Fagard, R., Narkiewicz, K., Redon, J., Zanchetti, A., Böhm, M., Christiaens, T., Cífková, R., Backer, G. D., et al. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht151 · Cited by 13,739
Chobanian, A. V., Bakris, G. L., Black, H. R., Cushman, W. C., Green, L. A., Izzo, J. L., Jones, D. W., Materson, B. J., Oparil, S., Wright, J. T., et al. (2003) · Hypertension · doi:10.1161/01.hyp.0000107251.49515.c2 · Cited by 13,271
Global burden of hypertension: analysis of worldwide data
Kearney, P. M., Whelton, M., Reynolds, K., Muntner, P., Whelton, P. K., & He, J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)17741-1 · Cited by 8,698
Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655
Development of a Classification System for Periodontal Diseases and Conditions
Armitage, G. C. (1999) · Annals of Periodontology · doi:10.1902/annals.1999.4.1.1 · Cited by 5,110
Pihlstrom, B. L., Michalowicz, B. S., & Johnson, N. W. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67728-8 · Cited by 3,718
Petersen, P. E. (2003) · Community Dentistry And Oral Epidemiology · doi:10.1046/j..2003.com122.x · Cited by 3,179
Global burden of blood-pressure-related disease, 2001
Lawes, C. M. M., Hoorn, S. V., & Rodgers, A. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60655-8 · Cited by 2,314
Research works printed but not linked: 2
- Zainoddin, 2013, Systemic conditions in patients with periodontal disease, Int Med J
- Shamsuddin, 2015, Hypertension and its association with the severity of chronic periodontitis: a preliminary study, Arch Orofacial Sci, 10, 3
Cited by
Sorted by citations
Periodontitis is associated with hypertension: a systematic review and meta-analysis
Muñoz Aguilera, E., Suvan, J., Buti, J., Czesnikiewicz-Guzik, M., Barbosa Ribeiro, A., Orlandi, M., Guzik, T. J., Hingorani, A. D., Nart, J., & D’Aiuto, F. (2020) · Cardiovascular Research · doi:10.1093/cvr/cvz201 · Cited by 394
Sideri, S., Papageorgiou, S. N., & Eliades, T. (2018) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2018.01.003 · Cited by 388
The association of periodontal diseases with metabolic syndrome and obesity
Jepsen, S. V., Suvan, J. E., & Deschner, J. (2020) · Periodontology 2000 · doi:10.1111/prd.12326 · Cited by 325
Evaluating All Potential Oral Complications of Diabetes Mellitus
Verhulst, M. J. L., Loos, B. G., Gerdes, V. E. A., & Teeuw, W. J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00056 · Cited by 294
Periodontitis and implant complications in diabetes
Nibali, L., Gkranias, N., Mainas, G., & Pino, A. D. (2022) · Periodontology 2000 · doi:10.1111/prd.12451 · Cited by 187
Metadata
- Authors
- Martin-Cabezas, R., Seelam, N., Petit, C., Agossa, K., Gaertner, S., Tenenbaum, H., Davideau, J.-L., & Huck, O.
- Affiliations
- Université de Strasbourg (FR)
- Université de Lille (FR)
- Hôpitaux Universitaires de Strasbourg (FR)
- Inserm (FR)
- Corresponding author
- Huck, Olivier
- Venue
- American Heart Journal
- Publisher
- Elsevier BV
- Published
- 2016-10
- Volume
- 180
- Pages
- 98-112
- ISSN
- 0002-8703 (ISSN-L)
- OpenAlex
- W2487600428
- Cited by
- 183
- References
- 58
- Citations by year
- 2026: 7 · 2025: 6 · 2024: 16 · 2023: 27 · 2022: 25 · 2021: 27 · 2020: 30 · 2019: 18 · 2018: 13 · 2017: 14
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Heart Journal (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
- Keywords
- periodontitis, hypertension, periodontal disease, severe periodontitis, cardiovascular risk factors, shared risk factors, associative strength
- MeSH terms
- Humans, Hypertension, Periodontitis, Risk Factors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
