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Cited by 183Oral microbiology and periodontitis researchBlood Pressure and Hypertension StudiesPeriodontal Regeneration and Treatments

The DOI matches its Crossref record; 57 of the 58 references it cites were found in a registry or an index.

Association between periodontitis and arterial hypertension: A systematic review and meta-analysis

Martin-Cabezas, Rodrigo, Seelam, Narendra, Petit, Catherine, Agossa, Kévimy, Gaertner, Sébastien, Tenenbaum, Henri, Davideau, Jean-Luc, Huck, Olivier·2016·American Heart Journal
DOI 10.1016/j.ahj.2016.07.018
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Abstract

Background Several studies have shown that periodontal diseases are associated with hypertension (HT). However, heterogeneity among populations, diagnosis criteria, and shared risk factors represent some difficulties in terms of interpretation. Therefore, the aim of this study was to determine the magnitude of the association between periodontal diseases and HT.Methods and results A systematic review and meta-analysis, including studies published up to June 2016, have been performed. Sixteen studies assessing the association between periodontal diseases and HT have been included. The meta-analysis considering all included studies (moderate to severe periodontitis) showed that the presence of HT was associated with the presence of periodontal diseases (OR, 1.50; 95% CI, 1.27-1.78). To reduce potential bias, a stratified analysis has been performed illustrating the impact of inclusion criteria and adjustments on the magnitude of the association. Interestingly, when only studies with secure diagnosis of severe periodontitis and HT were considered, an OR=1.64 (95% CI, 1.23-2.19) has been measured.Conclusions Periodontal diseases are associated with a higher risk of HT especially for severe periodontitis. However, no conclusions could be made regarding the causative involvement of periodontal diseases mainly due to the reduced number of available prospective studies and remaining questions regarding underlying biological mechanisms.

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Crossref · 10.1016/j.ahj.2016.07.018

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1 of the 58 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. Zainoddin, 2013, Systemic conditions in patients with periodontal disease, Int Med J
  2. Shamsuddin, 2015, Hypertension and its association with the severity of chronic periodontitis: a preliminary study, Arch Orofacial Sci, 10, 3

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Metadata

Authors
Martin-Cabezas, R., Seelam, N., Petit, C., Agossa, K., Gaertner, S., Tenenbaum, H., Davideau, J.-L., & Huck, O.
Affiliations
  • Université de Strasbourg (FR)
  • Université de Lille (FR)
  • Hôpitaux Universitaires de Strasbourg (FR)
  • Inserm (FR)
Corresponding author
Huck, Olivier
ORCID
Venue
American Heart Journal
Publisher
Elsevier BV
Published
2016-10
Volume
180
Pages
98-112
ISSN
0002-8703 (ISSN-L)
DOI
10.1016/j.ahj.2016.07.018
OpenAlex
W2487600428
Cited by
183
References
58
Citations by year
2026: 7 · 2025: 6 · 2024: 16 · 2023: 27 · 2022: 25 · 2021: 27 · 2020: 30 · 2019: 18 · 2018: 13 · 2017: 14
FWCI
2.59
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • American Heart Journal (publishedVersion)
  • PubMed (publishedVersion)
  • HAL (submittedVersion)
Topics
  • Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Dentistry › Periodontics › Periodontal Regeneration and Treatments
Keywords
periodontitis, hypertension, periodontal disease, severe periodontitis, cardiovascular risk factors, shared risk factors, associative strength
MeSH terms
Humans, Hypertension, Periodontitis, Risk Factors

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