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Ethiopian Genetic Diversity Reveals Linguistic Stratification and Complex Influences on the Ethiopian Gene Pool
Open accessAbstract
Humans and their ancestors have traversed the Ethiopian landscape for millions of years, and present-day Ethiopians show great cultural, linguistic, and historical diversity, which makes them essential for understanding African variability and human origins. We genotyped 235 individuals from ten Ethiopian and two neighboring (South Sudanese and Somali) populations on an Illumina Omni 1M chip. Genotypes were compared with published data from several African and non-African populations. Principal-component and STRUCTURE-like analyses confirmed substantial genetic diversity both within and between populations, and revealed a match between genetic data and linguistic affiliation. Using comparisons with African and non-African reference samples in 40-SNP genomic windows, we identified "African" and "non-African" haplotypic components for each Ethiopian individual. The non-African component, which includes the SLC24A5 allele associated with light skin pigmentation in Europeans, may represent gene flow into Africa, which we estimate to have occurred ~3 thousand years ago (kya). The non-African component was found to be more similar to populations inhabiting the Levant rather than the Arabian Peninsula, but the principal route for the expansion out of Africa ~60 kya remains unresolved. Linkage-disequilibrium decay with genomic distance was less rapid in both the whole genome and the African component than in southern African samples, suggesting a less ancient history for Ethiopian populations.
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“(b) Levantine ancestry in different Eastern African population in the dataset of Pagani et al. (2012); the remainder of the ancestry is a clade with Mota, a ~4,500 year old sample from Ethiopia50.”
From Genomic insights into the origin of farming in the ancient Near East (2016) · cites this paper as Pagani et al. (2012)
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“We can rule out the hypothesis that European farmers stem directly from a population related to the ancient farmers of the southern Levant29,30, however, since they share more allele with Anatolian Neolithic farmers than with Levantine farmers as attested by the positive statistic f4(Europe_EN, Chimp; Anatolia_N, Levant_N) (Z=15).”
From Genomic insights into the origin of farming in the ancient Near East (2016) · cites this paper as [30]
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PLINK: a tool set for whole-genome association and population-based linkage analyses.
Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M. A. R., Bender, D., Maller, J., Sklar, P., de Bakker, P. I. W., Daly, M. J., et al. (2007) · The American Journal of Human Genetics · doi:10.1086/519795 · Cited by 34,089
Principal components analysis corrects for stratification in genome-wide association studies
Price, A. L., Patterson, N. J., Plenge, R. M., Weinblatt, M. E., Shadick, N. A., & Reich, D. (2006) · Nature Genetics · doi:10.1038/ng1847 · Cited by 10,248
Fast model-based estimation of ancestry in unrelated individuals
Alexander, D. H., Novembre, J., & Lange, K. (2009) · Genome Research · doi:10.1101/gr.094052.109 · Cited by 9,898
A map of human genome variation from population-scale sequencing.
The 1000 Genomes Project Consortium (2010) · Nature · doi:10.1038/nature09534 · Cited by 7,877
A New Statistical Method for Haplotype Reconstruction from Population Data
Stephens, M., Smith, N. J. C., & Donnelly, P. (2001) · The American Journal of Human Genetics · doi:10.1086/319501 · Cited by 7,512
Integrating common and rare genetic variation in diverse human populations
The International HapMap 3 Consortium (2010) · Nature · doi:10.1038/nature09298 · Cited by 3,026
A Map of Recent Positive Selection in the Human Genome
Voight, B. F., Kudaravalli, S., Wen, X., & Pritchard, J. K. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040072 · Cited by 2,925
Inference of human population history from individual whole-genome sequences
Li, H., & Durbin, R. (2011) · Nature · doi:10.1038/nature10231 · Cited by 2,590
Genome-wide detection and characterization of positive selection in human populations
The International HapMap Consortium, Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X., Byrne, E. H., McCarroll, S. A., et al. (2007) · Nature · doi:10.1038/nature06250 · Cited by 2,131
Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation
Li, J. Z., Absher, D. M., Tang, H., Southwick, A. M., Casto, A. M., Ramachandran, S., Cann, H. M., Barsh, G. S., Feldman, M. W., Cavalli-Sforza, L. L., et al. (2008) · Science · doi:10.1126/science.1153717 · Cited by 1,915
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Lazaridis, I., Nadel, D., Rollefson, G., Merrett, D. C., Rohland, N., Mallick, S., Fernandes, D., Novak, M., Gamarra, B., Sirak, K., et al. (2016) · Nature · doi:10.1038/nature19310 · Cited by 955
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Gurdasani, D., Carstensen, T., Ayele, F. T., Pagani, L., Tachmazidou, I., Hatzikotoulas, K., Karthikeyan, S., Iles, L., Pollard, M., Choudhury, A., et al. (2014) · Nature · doi:10.1038/nature13997 · Cited by 659
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Lawson, D. J., van Dorp, L., & Falush, D. (2018) · Nature Communications · doi:10.1038/s41467-018-05257-7 · Cited by 560
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Kreplak, J., Madoui, M., Cápal, P., Novák, P., Labadie, K., Aubert, G., Bayer, P. E., Gali, K. K., Syme, R. A., Main, D., et al. (2019) · Nature Genetics · doi:10.1038/s41588-019-0480-1 · Cited by 573
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Schlebusch, C. M., Malmström, H., Günther, T., Sjödin, P., Coutinho, A., Edlund, H., Munters, A. R., Vicente, M., Steyn, M., Soodyall, H., et al. (2017) · Science · doi:10.1126/science.aao6266 · Cited by 519
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Scerri, E. M. L., Thomas, M., Manica, A., Gunz, P., Stock, J. T., Stringer, C. B., Grove, M. L., Groucutt, H. S., Timmermann, A., Rightmire, G. P., et al. (2018) · Trends in Ecology & Evolution · doi:10.1016/j.tree.2018.05.005 · Cited by 514
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Skoglund, P., Thompson, J. C., Prendergast, M. E., Mittnik, A., Sirak, K. A., Hajdinjak, M., Salie, T., Rohland, N., Mallick, S., Peltzer, A., et al. (2017) · Cell · doi:10.1016/j.cell.2017.08.049 · Cited by 422
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Pagani, L., Schiffels, S., Gurdasani, D., Danecek, P., Scally, A., Chen, Y., Xue, Y., Haber, M., Ekong, R., Oljira, T., et al. (2015) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2015.04.019 · Cited by 216
Self-citationvan Dorp, L., Balding, D. J., Myers, S., Pagani, L., Tyler‐Smith, C., Bekele, E., Tarekegn, A., Thomas, M., Bradman, N., & Hellenthal, G. (2015) · PLoS Genetics · doi:10.1371/journal.pgen.1005397 · Cited by 254
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Huerta‐Sánchez, E., DeGiorgio, M., Pagani, L., Tarekegn, A., Ekong, R., Antão, T., Cardona, A., Montgomery, H., Cavalleri, G. L., Robbins, P. A., et al. (2013) · Molecular Biology and Evolution · doi:10.1093/molbev/mst089 · Cited by 223
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Prendergast, M. E., Lipson, M., Sawchuk, E., Olalde, Í., Ogola, C. A., Rohland, N., Sirak, K. A., Adamski, N., Bernardos, R. L., Broomandkhoshbacht, N., et al. (2019) · Science · doi:10.1126/science.aaw6275 · Cited by 204
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Ongaro, L., Scliar, M. O., Flores, R., Raveane, A., Marnetto, D., Sarno, S., Gnecchi-Ruscone, G. A., Alarcón-Riquelme, M. E., Patin, E., Wangkumhang, P., et al. (2019) · Current Biology · doi:10.1016/j.cub.2019.09.076 · Cited by 114
Self-citationComas, I., Hailu, E., Kiros, T., Bekele, S., Mekonnen, W., Gumi, B., Tschopp, R., Ameni, G., Hewinson, R. G., Robertson, B. D., et al. (2015) · Current Biology · doi:10.1016/j.cub.2015.10.061 · Cited by 102
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Podgorná, E., Diallo, I., Vangenot, C., Sanchez‐Mazas, A., Sabbagh, A., Černý, V., & Poloni, E. S. (2015) · BMC Evolutionary Biology · doi:10.1186/s12862-015-0543-6 · Cited by 38
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Ramsay, M. (2012) · FEBS Letters · doi:10.1016/j.febslet.2012.07.061 · Cited by 38
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López, S., Tarekegn, A., Band, G., van Dorp, L., Bird, N., Morris, S., Oljira, T., Mekonnen, E., Bekele, E., Blench, R. M., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23712-w · Cited by 43
Self-citationLucock, M. D. (2023) · American Journal of Biological Anthropology · doi:10.1002/ajpa.24564 · Cited by 35
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Aklillu, E., Habtewold, A., Ngaimisi, E., Yimer, G., Mugusi, S. F., Amogne, W., Reuter, T., Meid, A. D., Hoffmann, M. M., & Weiß, J. (2016) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2016.0119 · Cited by 26
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Sertse, D., You, F. M., Ravichandran, S., & Cloutier, S. (2019) · Molecular Phylogenetics and Evolution · doi:10.1016/j.ympev.2019.04.010 · Cited by 26
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Priehodová, E., Austerlitz, F., Čížková, M., Mokhtar, M. G., Poloni, E. S., & Černý, V. (2017) · American Journal of Human Biology · doi:10.1002/ajhb.22950 · Cited by 23
Vyas, D. N., Al‐Meeri, A., & Mulligan, C. J. (2017) · American Journal of Physical Anthropology · doi:10.1002/ajpa.23312 · Cited by 21
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Ali, A. A., Aalto, M., Jonasson, J., & Osman, A. (2020) · Scientific Reports · doi:10.1038/s41598-020-62645-0 · Cited by 22
Tarekegn, G. M., Khayatzadeh, N., Liu, B., Osama, S. K., Haile, A., Rischkowsky, B., Zhang, W., Tesfaye, K., Dessie, T., Mwai, O. A., et al. (2020) · Evolutionary Applications · doi:10.1111/eva.13118 · Cited by 22
Yelmen, B., Mondal, M., Marnetto, D., Pathak, A. K., Montinaro, F., Romero, I. G., Kivisild, T., Metspalu, M., & Pagani, L. (2019) · Molecular Biology and Evolution · doi:10.1093/molbev/msz037 · Cited by 23
Self-citationMosaic maternal ancestry in the Great Lakes region of East Africa
Gomes, V., Pala, M., Salas, A., Álvarez‐Iglesias, V., Amorim, A., Gómez‐Carballa, A., Carracedo, Á., Clarke, D. J., Hill, C., Mormina, M., et al. (2015) · Human Genetics · doi:10.1007/s00439-015-1583-0 · Cited by 22
Fleskes, R. E., Cabana, G. S., Gilmore, J. K., Juarez, C. A., Karcher, E., Oubré, L., Mishoe, G., Ofunniyin, A. A., & Schurr, T. G. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2201620120 · Cited by 22
Metadata
- Authors
- Pagani, L., Kivisild, T., Tarekegn, A., Ekong, R., Plaster, C., Gallego Romero, I., Ayub, Q., Mehdi, S. Q., Thomas, M. G., Luiselli, D., Bekele, E., Bradman, N., Balding, D. J., & Tyler-Smith, C.
- Affiliations
- University of Cambridge (GB)
- Addis Ababa University (ET)
- University College London (GB)
- Wellcome Sanger Institute (GB)
- Sindh Institute of Urology and Transplantation (PK)
- University of Bologna (IT)
- Corresponding author
- Pagani, Luca
- ORCID
- Venue
- The American Journal of Human Genetics
- Publisher
- Elsevier BV
- Published
- 2012-07
- Volume
- 91
- Issue
- 1
- Pages
- 83-96
- ISSN
- 0002-9297 (ISSN-L)
- PMC
- PMC3397267
- OpenAlex
- W2089722101
- Cited by
- 230
- References
- 55
- Citations by year
- 2026: 7 · 2025: 49 · 2024: 1 · 2023: 17 · 2022: 16 · 2021: 11 · 2020: 14 · 2019: 20 · 2018: 18 · 2017: 12 · 2016: 14 · 2015: 23 · 2014: 19 · 2013: 6 · 2012: 3
- FWCI
- 9.83
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- The American Journal of Human Genetics (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Archivio istituzionale della ricerca (Alma Mater Studiorum Università di Bologna) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Padua Research Archive (University of Padova) (submittedVersion)
- Funders
- Wellcome Trust (098051)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Forensic and Genetic Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic diversity and population structure
- Social Sciences › Anthropology › Race, Genetics, and Society
- Keywords
- Ethiopian population, genetic diversity, linguistic stratification, SLC24A5, out-of-Africa migration, Levant, linkage disequilibrium decay, human origins, Somali
- MeSH terms
- Emigration and Immigration, Ethiopia, Gene Pool, Genotype, Haplotypes, Humans, Language, Phylogeny, Genetic Variation, Linkage Disequilibrium, Black People, Phylogeography
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