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Chromosomal and gonadal factors regulate microglial sex effects in the aging brain

Ocañas, S. R., Ansere, V. A., Kellogg, C. M., Isola, J. V. V., Chucair‐Elliott, A. J., & Freeman, W. M. (2023) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2023.02.008 · Cited by 25

Investigation of chromosome Y loss in men with schizophrenia

Hirata, T., Hishimoto, A., Otsuka, I., Okazaki, S., Boku, S., Kimura, A., Horai, T., & Sora, I. (2018) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s172886 · Cited by 24

TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice

Matatall, K. A., Wathan, T. K., Nguyen, M., Chen, H., McDonald, A., Qi, G., Belk, J. A., Florez, M. A., Le, D. T., Olarinde, T., et al. (2025) · Cell Stem Cell · doi:10.1016/j.stem.2025.06.006 · Cited by 23

Loss of Y in regulatory T lymphocytes in the tumor micro-environment of primary colorectal cancers and liver metastases

Wójcik, M., Juhas, U., Mohammadi, E., Mattisson, J., Drężek-Chyła, K., Rychlicka-Buniowska, E., Bruhn‐Olszewska, B., Davies, H., Chojnowska, K., Olszewski, P., et al. (2024) · Scientific Reports · doi:10.1038/s41598-024-60049-y · Cited by 23

Illegitimate and Repeated Genomic Integration of Cell-Free Chromatin in the Aetiology of Somatic Mosaicism, Ageing, Chronic Diseases and Cancer

Raghuram, G. V., Chaudhary, S., Johari, S. D., & Mittra, I. (2019) · Genes · doi:10.3390/genes10060407 · Cited by 22

Genetic association of mosaic loss of chromosome Y with prostate cancer in men of European and East Asian ancestries: a Mendelian randomization study

Kobayashi, T., Hachiya, T., Ikehata, Y., & Horie, S. (2023) · Frontiers in Aging · doi:10.3389/fragi.2023.1176451 · Cited by 23

Somatic Mosaicism in Biology and Disease

Ogawa, H., Horitani, K., Izumiya, Y., & Sano, S. (2021) · Annual Review of Physiology · doi:10.1146/annurev-physiol-061121-040048 · Cited by 22

The role of genetics and epigenetics in sex differences in human survival

Iannuzzi, V., Bacalini, M. G., Franceschi, C., & Giuliani, C. (2023) · Genus · doi:10.1186/s41118-023-00181-1 · Cited by 20

Why Y matters? The implication of loss of Y chromosome in blood and cancer

Wang, Y., & Sano, S. (2024) · Cancer Science · doi:10.1111/cas.16072 · Cited by 21

Y Chromosome Loss and Implications for Oncology

Dirican, C. D., & Nelson, P. S. (2024) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-24-0105 · Cited by 22

Exploring the role of sex differences in Alzheimer's disease pathogenesis in Down syndrome

Andrews, E. J., Martini, A. C., & Head, E. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.954999 · Cited by 21

The Y chromosome: male reproduction and beyond

Krausz, C. G., & Abrardo, C. (2025) · Fertility and Sterility · doi:10.1016/j.fertnstert.2025.03.006 · Cited by 21

Y Chromosome Loss Is a Frequent Event in Barrett’s Adenocarcinoma and Associated with Poor Outcome

Loeser, H., Wölwer, C. B., Alakus, H., Chon, S., Zander, T., Buettner, R., Hillmer, A. M., Bruns, C. J., Schroeder, W., Gebauer, F., et al. (2020) · Cancers · doi:10.3390/cancers12071743 · Cited by 19

Mosaic Loss of Chromosome Y Is Associated With Functional Outcome After Ischemic Stroke

Dorvall, M., Pedersén, A., Dumanski, J. P., Söderholm, M., Lindgren, A. G., Stanne, T. M., & Jern, C. (2023) · Stroke · doi:10.1161/strokeaha.123.043551 · Cited by 19

Loss of Chromosome Y and Its Potential Applications as Biomarker in Health and Forensic Sciences

Barros, B., Morais, M., Teixeira, A. L., & Medeiros, R. (2020) · Cytogenetic and Genome Research · doi:10.1159/000508564 · Cited by 19

MADloy: robust detection of mosaic loss of chromosome Y from genotype-array-intensity data

González, J. R., López‐Sánchez, M., Cáceres, A., Puig, P., Esko, T., & Jurado, L. A. P. (2020) · BMC Bioinformatics · doi:10.1186/s12859-020-03768-z · Cited by 18

Sex-based differences in effector cells of the adaptive immune system during Alzheimer's disease and related dementias

Lutshumba, J., Wilcock, D. M., Monson, N. L., & Stowe, A. M. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106202 · Cited by 20

Glyphosate Use and Mosaic Loss of Chromosome Y among Male Farmers in the Agricultural Health Study

Chang, V. C., Zhou, W., Berndt, S. I., Andreotti, G., Yeager, M., Parks, C. G., Sandler, D. P., Rothman, N., Freeman, L. E. B., Machiela, M. J., et al. (2023) · Environmental Health Perspectives · doi:10.1289/ehp12834 · Cited by 18

Minding the Gap: Exploring Neuroinflammatory and Microglial Sex Differences in Alzheimer’s Disease

Reed-Geaghan, E. G., & Keller-Norrell, P. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417377 · Cited by 19

Tissue mosaicism following stem cell aging: blood as an exemplar

Kapadia, C. D., & Goodell, M. A. (2024) · Nature Aging · doi:10.1038/s43587-024-00589-0 · Cited by 18

Inflammatory cytokine storms severity may be fueled by interactions of micronuclei and RNA viruses such as COVID-19 virus SARS-CoV-2. A hypothesis

Kirsch‐Volders, M., & Fenech, M. F. (2021) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2021.108395 · Cited by 20

Why Y? Downregulation of Chromosome Y Genes Potentially Contributes to Elevated Cancer Risk

Brown, D. W., & Machiela, M. J. (2019) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djz236 · Cited by 18

Somatic Loss of the Y Chromosome and Alzheimer’s Disease Risk

Cukier, H. N., Palmer, E. L., Benchek, P. H., Wheeler, N. R., Smeisek, S., Naj, A. C., Haines, J. L., Pericak‐Vance, M. A., Forsberg, L. A., Song, Y. E., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.090093 · Cited by 2

P3‐129: SOMATIC LOSS OF Y CHROMOSOME IN THE ADGC COHORTS

Bush, W. S., Smieszek, S. P., Song, Y. E., Naj, A. C., Forsberg, L. A., & Haines, J. L. (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2019.06.3157

Mendelian randomization confirms the role of Y-chromosome loss in Alzheimer’s Disease etiopathogenesis in malesPreprint

García‐González, P., de Rojas, I., Moreno–Grau, S., Montrreal, L., Puerta, R., Alarcón‐Martín, E., Quintela, I., Orellana, A., Andrade, V., Adami, P. V. M., et al. (2022) · medRxiv · doi:10.1101/2022.07.20.22277657 · Cited by 3

Mosaic Loss of Chromosome Y in Peripheral Blood Cells from Whole‐Genome Sequencing and Alzheimer’s Disease in the Amish

Song, Y. E., Laux, R. A., Fuzzell, S. L., Hochstetler, S. D., Miskimen, K. L. S., Lynn, A., Wang, W., Main, L. R., Wang, P., Liu, Y., et al. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.089681

Automatic determination of blood cholesterol

Boy, J. (1963) · Journal of Clinical Pathology · doi:10.1136/jcp.16.2.178 · Cited by 7